Abstract：
:Patent ductus arteriosus (PDA) is a major morbidity in preterm infants, especially in extremely premature infants less than 28 weeks. The clinical signs and symptoms of PDA in preterm infants are non specific and insensitive for making an early diagnosis of significant ductal shunting. Functional echocardiography is emerging as a new valuable bedside tool for early diagnosis of hemodynamically significant ductus, even though there are no universally accepted criteria for grading the hemodynamic significance. Echocardiography has also been used for early targeted treatment of ductus arteriosus, though the long term benefits of such strategy are debatable. The biomarkers like BNP and N terminal pro BNP are currently under research as diagnostic marker of PDA. The primary mode of treatment for PDA is pharmacological closure using cyclo-oxygenase inhibitors with closure rate of 70-80%. Oral ibuprofen is emerging as a better alternative especially in Indian scenario where parenteral preparations of indomethacin are unavailable and side effects are comparatively lesser. Though pharmacological closure of PDA is an established treatment modality, there is still lack of evidence for long term benefits of such therapy as well as there is some evidence for the possible adverse effects like increased ROP and BPD rates, especially if treated prophylactically. Hence, it is prudent to reserve treatment of PDA to infants with clinically significant ductus on the basis of gestation, birth weight, serial echocardiography and clinical status to individualize the decision to treat.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Sasi A,Deorari Adoi
10.1007/s13312-011-0062-5subject
Has Abstractpub_date
2011-04-01 00:00:00pages
301-8issue
4eissn
0019-6061issn
0974-7559journal_volume
48pub_type
杂志文章,评审abstract：OBJECTIVE:To provide tribe- specific child mortality rates and health indicators from selected states in India. METHODS:We used Census 2011 data and Coale Demney methodology to estimate the infant mortality rate (IMR), under-five mortality rate (U5MR) and expectation of life at birth (LEB) for 123 tribes of selected s...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2021-01-15 00:00:00
abstract：:Highly active antiretroviral therapy is beyond reach of most HIV-infected children in developing countries. There is paucity of data on more affordable regimens such as ones based on nevirapine and 2 nucleoside reverse transcriptase inhibitors. We report our experience with the use of antiretroviral therapy in childre...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2005-08-01 00:00:00
abstract：OBJECTIVE:To estimate the prevalence of Iodine Deficiency Disorders, and household consumption of adequately iodized salt in Damoh district, Madhya Pradesh in 2016. METHODS:Cross-sectional study with cluster sampling method was used among school-going children. 30 clusters, each with 90 children were selected to acces...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2018-07-15 00:00:00
abstract：:A cross sectional study was conducted in 260 adolescent schoolchildren (114 males) in the age group of 11-18 years to estimate the prevalence of zinc deficiency in the National Capital Territory of Delhi. Serum zinc was estimated using Inductively coupled plasma mass spectrometer. Overall, 49.4% children (50.8% males,...
journal_title：Indian pediatrics
pub_type： 信件
doi：
更新日期：2011-12-01 00:00:00
abstract：:In the newborn period, unconjugated hyperbilirubinemia (UHB) is common, multifactoral, and associated with a variety of physiologic and pathologic conditions. The most commonly identified pathologic cause leading to hyperbilirubinemia is hemolytic disease of the newborn. We report a five-days-old female infant with ne...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：:We report a 71/2-year-boy with disseminated systemic cryptococcosis. Although other species have been incriminated, this appears to be the first report of Cryptococcus humicolus. The child was HIV negative. He was treated with amphotericin B and fluconazole with intensive supportive care. The child responded after 6 w...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2004-11-01 00:00:00
abstract：BACKGROUND:Auxiliary partial orthotopic liver transplantation is a technique where part of diseased native liver is removed and replaced with healthy donor liver so that, the left behind native liver could later regenerate. CASE CHARACTERISTICS:2 year 6 month old girl with acute liver failure due to Hepatitis A. She u...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-016-0795-2
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND:Outcome of pseudomonas enteric fever is unpredictable as multiple systemic lethal complications occur abruptly. CASE CHARACTERISTICS:A 9-month-old girl with multiple ileal perforations, leukocoria, ecthyma gangrenosum, hemiplegia and a perforated ulcer in the soft palate. Blood culture suggested Pseudomonas...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-015-0741-8
更新日期：2015-10-01 00:00:00
abstract：:Transfusion-related acute lung injury is a rare form of acute respiratory distress syndrome of possible immune etiology that develops immediately after a blood product transfusion. Clinicians need to be aware of this condition as prompt recognition and supportive management can prevent unwanted morbidity and mortality...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2012-02-01 00:00:00
abstract：OBJECTIVE:To document effects of intrapartum risk factors for early onset sepsis (EOS) on CRP levels in neonates and to assess the suitability of this test in diagnosing EOS. DESIGN:Cohort study. SETTING:Labour and post natal wards in a tertiary level teaching hospital in India. SUBJECTS:250 neonates at risk of deve...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2004-09-01 00:00:00
abstract：:Seventy five mothers with lactation failure were studied, whose less than 4-month-old babies were admitted to the hospital. Partial lactational failure (94.7%) was noted more often than complete lactational failure (5.3%). Initiation of breastfeeding was delayed for 2 to 5 days usually for traditional reasons (77.3%) ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1992-12-01 00:00:00
abstract：OBJECTIVES:To evaluate efficacy of polymerase chain reaction (PCR), using the insertion sequence IS6110 as target for DNA, to detect Mycobacterium tuberculosis in body fluids of children with suspected tuberculosis (TB). SETTING:Hospitalized patients. METHODS:A comparison of PCR on body fluids, Acid Fast Bacilli stai...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2000-04-01 00:00:00
abstract：:Sixty children with acute bacterial meningitis (ABM) were prospectively studied for their serum sodium values and cerebrospinal fluid (CSF), serum and urinary osmolality. The results have been compared with 20 age and nutritionally matched controls. Even though mean serum osmolality (283.2 +/- 13.84 mOsm/kg) and serum...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1993-10-01 00:00:00
abstract：OBJECTIVE:To evaluate the effectiveness of a community oral health awareness program given to mothers through trained community level workers (Junior Public Health Nurses (JPHNs) and Anganwadi workers (AWWs). METHODS:Oral health education materials were prepared based on the findings of a knowledge survey among commun...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:A quadrivalent MMRV (measles-mumps-rubella-varicella) combination vaccine has recently been launched in India. This vaccine is highly immunogenic, with seroconversion rates against all antigens reaching 96.6-100% at 42 to 56 days after the second vaccine dose in unvaccinated children or in those previously vaccinated ...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s13312-017-1209-9
更新日期：2017-12-15 00:00:00
abstract：:Meropenem is a new carbapenem antibacterial agent with wide spectrum of activity against gram-negative, gram-positive and anaerobic organisms. It is stable against most beta-lactamases produced by gram-negative bacteria and has greatest utility in treating severe infections in hospitalized children. It has good CSF pe...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：2005-05-01 00:00:00
abstract：OBJECTIVE:To study the incidence and risk factors predisposing to retinopathy of prematurity (ROP) and to assess the outcome after laser photocoagulation. DESIGN:Prospective cohort observational study. SETTING:Infants admitted to a neonatal intensive care unit of a referral hospital between 2000-2006 and followed up ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2009-03-01 00:00:00
abstract：:Postictal values of plasma prolactin levels were measured in 15 children with generalized seizures, 8 children with pseudoseizures and 6 control subjects. In patients with generalized seizure, the mean plasma prolactin level was 28.6 +/- 2.3 ng/ml, whereas in patients with pseudoseizures and in controls, its mean valu...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1994-06-01 00:00:00
abstract：OBJECTIVE:To assess the glycometabolic function in chronically transfused patients of beta- thalassemia major in terms of glucose tolerance, insulin secretion, insulin resistance index, and beta cell function index and to determine their relationship with clinical and biochemical profile. METHODS:30 homozygous thalass...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2006-05-01 00:00:00
abstract：:Seven cases of benign form of spinal muscular atrophy were studied to evaluate the importance of detecting hand tremors, muscle fasciculation, evertion of foot and ECG tremors to distinguish these cases from muscular dystrophy. Taken in combination, diagnosis of all the seven cases was possible without the need for ap...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1989-10-01 00:00:00
abstract：OBJECTIVE:To study the clinical profile and outcome of langerhans cell histiocytosis in children upto 2 years of life. DESIGN:Retrospective analysis. METHODS:Medical records of Children upto 2 years of age with a diagnosis of langerhans cell histiocytosis (LCH) were analyzed. Their clinical pattern, treatment modalit...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:The present study was conducted to evaluate and compare the specific cellular responses of children vaccinated with three different strains of BCG. The study comprised of normal children with normal weight and normal general responses (PHA) to in vitro leukocyte migration inhibition test (LMIT). The three strains of B...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1995-09-01 00:00:00
abstract：:A 6 month-old infant presenting with severe mitral regurgitation was found to have hepatosplenomegaly, corneal clouding, and Alder-Reilly granules in the leucocytes. Extremely low levels of beta glucuronidase confirmed the diagnosis of Sly disease (Mucopolysaccharidosis VII). This is the first case of MPS VII reported...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2008-10-01 00:00:00
abstract：:To identify an inexpensive, reliable predictor of low birth weight capable of being utilized by untrained personnel, anthropometric measures were performed on 1600 newborns in Kanpur, India. This analysis indicated that, for a birth weight of 2500 g, the critical limit of calf circumference was 10.8 cm or less. Crit...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1996-02-01 00:00:00
abstract：:An age-independent anthropometric index to identify undernourished children in the age group of 5-10 years is described. Employing a mathematical approach (linear regression analysis) on data from 238 children, the index was derived to be wt/(ht)2. Employing this index, a classification rule for identifying the undern...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1992-06-01 00:00:00
abstract：:We report a case of primary hyperparathyroidism associated with prolonged hungry syndrome (HBS) after parathyroid adenomectomy in a 10-year-old girl. Bone mineral density (BMD) revealed severe loss of cancellous BMD. Overt bone disease, high alkaline phosphatase, decreased cancellous BMD and a large adenoma can be use...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2009-02-01 00:00:00
abstract：:The retrospective study was carried out to examine performance of Pottels height- independent equation compared to Schwartzs height-dependent equation to estimate glomerular filtration rate in 115 children in Indian setting. The Pottels equation performed well compared to updated Schwartz equation (R2=0.94, mean bias ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-017-1001-x
更新日期：2017-01-15 00:00:00
abstract：:A major purpose of the immunization coverage evaluation surveys to document the vaccination status of children aged 1-2 years was to determine the true picture of the immunization status of the target population and to identify areas which need strengthening. Immunization coverage evaluation surveys were carried out f...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：BACKGROUND:Neuroschistosomiasis is an uncommonly reported disease. CASE CHARACTERISTICS:An adolescent Indian boy residing in Kenya presented with headache, visual symptoms and seizures, with MRI showing space-occupying lesions in the occipital lobe and cerebellum. OBSERVATION:Brain biopsy was diagnostic of neuro-schi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2018-11-15 00:00:00
abstract：OBJECTIVE:To evaluate the effect of canakinumab on growth parameters of patients with autoinflammatory diseases. METHODS:This retrospective study included Colchicine resistant familial Mediterranean fever (FMF), Mevalonate kinase deficiency (MKD), Tumor necrosis factor receptor-associated periodic fever syndrome (TRAP...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-07-15 00:00:00
