A New Combined Vaccine Against Measles, Mumps, Rubella and Varicella in India.

Abstract:

:A quadrivalent MMRV (measles-mumps-rubella-varicella) combination vaccine has recently been launched in India. This vaccine is highly immunogenic, with seroconversion rates against all antigens reaching 96.6-100% at 42 to 56 days after the second vaccine dose in unvaccinated children or in those previously vaccinated with MMR+/-V. Two doses efficacy, against all varicella is 94.1% and effectiveness reaches 91%. The most frequent solicited local adverse event after MMRV vaccine is redness, and fever is the most common solicited general symptom. Higher rates of fever and febrile convulsions compared to MMR+/-V have been reported when used as first dose but not when used as the second of a measles containing vaccine, irrespective of age of the second dose.

journal_name

Indian Pediatr

journal_title

Indian pediatrics

authors

Shah N,Parikh R,Casabona G,Kolhapure S

doi

10.1007/s13312-017-1209-9

subject

Has Abstract

pub_date

2017-12-15 00:00:00

pages

1041-1046

issue

12

eissn

0019-6061

issn

0974-7559

journal_volume

54

pub_type

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