Abstract：
OBJECTIVES:To evaluate efficacy of polymerase chain reaction (PCR), using the insertion sequence IS6110 as target for DNA, to detect Mycobacterium tuberculosis in body fluids of children with suspected tuberculosis (TB). SETTING:Hospitalized patients. METHODS:A comparison of PCR on body fluids, Acid Fast Bacilli staining (AFB), mycobacterial culture and clinical features, with special emphasis on central nervous system (CNS) TB was done over 18 month period. A total of 80 children were evaluated, 41 with probable TB disease and 39 controls. Cases were defined by specific clinical criteria. Controls included patients free of clinical TB. PCR was done on the clinical specimens and compared with clinical findings, radiological features, Mantoux (Mx) testing, AFB staining and culture on Lowenstein-Jensen (LJ) medium. RESULTS:Sensitivity of PCR in CSF samples was 100%, in gastric aspirate samples was 20% and in pleural fluid samples was 100%. CONCLUSION:PCR technique may become a valuable diagnostic tool for the diagnosis of tuberculosis in children especially in CNS TB.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Jatana SK,Nair MN,Lahiri KK,Sarin NPkeywords:
subject
Has Abstractpub_date
2000-04-01 00:00:00pages
375-82issue
4eissn
0019-6061issn
0974-7559journal_volume
37pub_type
杂志文章abstract：:In order to evaluate clinical and bacteriological efficacy of Cefpodoxime Proxetil (CP) in typhoid fever in comparison to cefixime (CF), we assessed 140 children with suspected typhoid fever. Fulfilling inclusion criteria finally 40 culture confirmed typhoid fever were allocated in randomized double blind clinical tri...
journal_title：Indian pediatrics
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2007-11-01 00:00:00
abstract：:A prospective study was performed on 44 patients (newborn to one year old) with acute bacterial meningitis. Sonograms were obtained within 72 hours of diagnosis, and repeated on 7th, 14th or at an early date, if required. The spectrum of sonographic features of meningitis included normal scan (35.4%), echogenic sulci ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1994-11-01 00:00:00
abstract：:Twenty five asphyxiated neonates had ECG changes consistent with degree of asphyxia. Equivocal changes were found in mild asphyxia and changes suggestive of myocardial infarction were seen with severe asphyxia. In most cases, the changes reverted to normal within two weeks signifying great ability of the neonatal hear...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：OBJECTIVE:To assess the effects of delayed cord clamping (DCC) on hemoglobin (Hb), mean corpuscular volume (MCV) and ferritin level in infants 2 months or older. EVIDENCE ACQUISITION:Meta-analysis of randomized control trials searched systematically from PubMed, Cochrane and Web of science. Trials published from Jan 1...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-09-15 00:00:00
abstract：:Fluconazole has been used as prophylaxis against systemic fungal infections in preterm neonates. We conducted a study to determine whether cessation of a policy of prophylactic fluconazole results in a resurgence of fungal infections in a unit. Neonates born in the 3 epoches: A 36-month pre-Fluconazole prophylaxis epo...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2005-12-01 00:00:00
abstract：:Acute interstitial nephritis (AIN) should be ruled out in children with unexplained acute renal failure. We present a 4 1/2 year old girl who presented with oliguric acute renal failure preceded by a febrile illness. Renal histopathology revealed features of drug induced AIN. She recovered with dialysis, other support...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2003-04-01 00:00:00
abstract：BACKGROUND:Blue rubber bleb nevus syndrome is a rare clinical entity. CASE CHARACTERISTICS:A 13-year-old Indian boy presented with characteristic cutaneous lesions, gastrointestinal malformations, skeletal involvement and pulmonary stenosis. OBSERVATIONS:Diagnosis was confirmed on skin biopsy, radiographic evaluation...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-016-0884-2
更新日期：2016-06-08 00:00:00
abstract：:We studied the actual time taken to document temperature in a stable neonate by an electronic digital skin thermometer with automatic time beeper. We studied 100 neonates after initial stabilization. The mean time required for documenting the temperature by a electronic thermometer in axilla was 56.34+/-1.54 secs for ...
journal_title：Indian pediatrics
pub_type： 信件
doi：
更新日期：2009-12-01 00:00:00
abstract：:In Kumbakonam, Tamil Nadu State in India, 384 final-year female students attending the Government College for Women completed a questionnaire so the researcher could assess their knowledge of prenatal and childhood immunizations, breast feeding, weaning, oral rehydration solution (ORS), and feeding during diarrhea. 5...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：OBJECTIVE:To compare the impact of postnatal lactational counseling on the weight gain and frequency of mixed feeding in full term neonates. DESIGN:Observational study. SETTING:Mother-infant pairs were observed in the maternity section of a multispecialty general hospital in Mumbai during two time periods. PARTICIPA...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-015-0678-y
更新日期：2015-07-01 00:00:00
abstract：:Hospital acquired enteric infections were investigated by studying 3138 children under 5 years of age who were admitted without diarrhea in nine medical words of a pediatric hospital, Calcutta during the period between March and September 1987. Three hundred and twenty (10.2%) children developed nosocomial diarrhea du...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1993-02-01 00:00:00
abstract：:A 13-year old girl presented with a decade long anemia, diffuse alveolar hemorrhage and interstistial lung disease; was eventually diagnosed as ANCA associated vasculitis. High index of suspicion is thus warranted for alternative diagnosis in chronic anemia, despite increased prevalence of infectious diseases and nutr...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0042-z
更新日期：2013-02-01 00:00:00
abstract：:The International Classification of Functioning, Disability and Health (ICF) is a framework for describing health status; however, there is a gap in literature for supporting its use as a classification tool. The purpose of this paper is to provide a perspective on its use in describing children with cerebral palsy. T...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-016-0935-8
更新日期：2016-09-08 00:00:00
abstract：OBJECTIVES:To identify important factors (linked to lifestyle, eating and sedentary behaviors) relating to waist circumference among urban South Indian children aged 3 to 16 years. DESIGN:Cross sectional. SETTING:Urban schools of Bangalore, from August 2008 to January 2010. PARTICIPANTS:8444 children; 4707 children ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-012-0027-3
更新日期：2012-02-01 00:00:00
abstract：:We assessed the clinical response and side effects of Ferrous sulfate (FS) and Iron polymaltose complex (IPC) in 118 children with Iron deficiency anemia (IDA). Subjects were randomized to receive therapy with either oral IPC (Group A, n=59) or oral FS (Group B, n=59); all were given elemental iron in three divided do...
journal_title：Indian pediatrics
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2009-10-01 00:00:00
abstract：:Salmonella senftenberg was isolated from the stools of 35 newborns between June, 1987 and September, 1988. Twenty nine (82.8%) babies were preterms and twenty six (74%) babies were less than 2,000 grams in weight. All of them were symptomatic within 6 days of life, 74.3% (26) within 4 days. All of them had loose stool...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1990-02-01 00:00:00
abstract：:This paper explores the relationships between maternal weight, height and poor pregnancy outcome using a data set from a case-control study of low birth weight (LBW) and perinatal mortality in Ahmedabad, India. Maternal height and weights were compared between mothers of 611 perinatal deaths, 644 preterm-LBW, and 1465...
journal_title：Indian pediatrics
pub_type： 杂志文章,多中心研究
doi：
更新日期：1994-10-01 00:00:00
abstract：:One hundred and four cases of osteoarticular tuberculosis were studied. There were 74 boys (71.2%) and 30 girls (28.8%). The mean age at the onset of symptoms was 7.3 years, ranging from 9 months to 18 years. Seventy four cases (71%) reported 3 months after onset of symptoms. The spine was the commonest site involved ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1992-09-01 00:00:00
abstract：:The objectives of this study were to evaluate whether a newborn or a neonate is capable of responding immunologically after BCG vaccination and to find out if this immunity persists for one year. Normal infants aged between 0 days-3 months brought to immunization centre were included in the study. In vitro leukocyte m...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1994-12-01 00:00:00
abstract：:Ensuring quality in healthcare today has become extremely essential to ensure adequate utilization of healthcare services and improved outcomes. In addition to essential infrastructure in terms of safe and adequate space, knowledgeable and skilled health workers, and essential equipment and supply, the healthcare team...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：2018-09-15 00:00:00
abstract：:In the present study, brainstorm auditory evoked responses (BAER) were recorded in 68 at risk neonates discharged from the neonatal ICU of Safdarjung Hospital. The high risk group of 35 neonates included 13 neonates with multiple (3-4) risk factors and 22 neonates with single risk factors, viz., prematurity (less than...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：:We conducted this study to ascertain whether health workers can routinely administer verbal autopsy (VA) to determine the cause of death in their area. The health workers were trained to administer verbal autopsy tool on the deaths occurring in the population under them. All the verbal autopsies of under-five deaths b...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2003-08-01 00:00:00
abstract：:A 2-yr-old child with early onset diabetes and hypothyroidism, and diagnosed as Wolcott-Rallison Syndrome, developed two episodes of acute liver failure and recovered, but he remains at high risk of developing another episode of acute liver failure. Autoimmune, metabolic or genetic disorders should be evaluated in chi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2019-12-15 00:00:00
abstract：OBJECTIVE:(i) To assess the severity of Iodine Deficiency Disorders (DD) in Baroda and Dang Districts of Gujarat, using biochemical prevalence indicators of IDD; and (ii) To establish a biochemical baseline, in a sub-sample of the large population of Gujarat, that could be used to monitor the effectiveness of iodine re...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2001-03-01 00:00:00
abstract：:Youth violence is a growing problem worldwide. Research on adolescent violence in India is limited. Fifteen hundred high school students were investigated to study the prevalence and demographic characteristics of witnesses, victims and perpetrators of violence and to see the impact of violence exposure on their psych...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2006-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of high dose phenobarbital on lipid peroxidation and antioxidant enzymes in perinatal asphyxia. DESIGN:Open label, Randomized controlled trial. SETTING:Neonatal intensive care unit of a tertiary care teaching hospital. PARTICIPANTS:72 full term inborn neonates with severe birth asphy...
journal_title：Indian pediatrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s13312-011-0106-x
更新日期：2011-08-01 00:00:00
abstract：BACKGROUND:High bilirubin level is toxic to developing brain and auditory system but the current debate surrounds the toxicity of bilirubin in healthy term infants. METHODS:Longitudinal observational study to find BERA abnormalities in term newborns with isolated hyperbilirubinemia of 20 mg/dL and more and to follow u...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-014-0346-7
更新日期：2014-02-01 00:00:00
abstract：OBJECTIVE:To determine the diagnostic accuracy of Indian Scale for Assessment of Autism (ISAA) in children aged between 2-5 years. Design: Setting:. STUDY DESIGN:Study of diagnostic accuracy. PARTICIPANTS:A consecutive sample of 500 children with suspected Autism (delay or regression of developmental milestones, dela...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2019-10-15 00:00:00
abstract：:A 6 month-old infant presenting with severe mitral regurgitation was found to have hepatosplenomegaly, corneal clouding, and Alder-Reilly granules in the leucocytes. Extremely low levels of beta glucuronidase confirmed the diagnosis of Sly disease (Mucopolysaccharidosis VII). This is the first case of MPS VII reported...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2008-10-01 00:00:00
abstract：:Fifty newborns, 25 full term SFDs (small for date) and 25 full term AGAs (appropriate for gestational age) were taken up for comparative study of their behavior using BNBAS (Brazelton's neonatal behavior assessment scale). The study revealed that full term SFDs performed significantly poorly on all items under cluster...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
