Abstract:
:In order to evaluate clinical and bacteriological efficacy of Cefpodoxime Proxetil (CP) in typhoid fever in comparison to cefixime (CF), we assessed 140 children with suspected typhoid fever. Fulfilling inclusion criteria finally 40 culture confirmed typhoid fever were allocated in randomized double blind clinical trial (RCT) to receive therapy with either oral CP (16 mg/kg/day, n = 21) or oral CF (20 mg/kg/day, n = 19) for 10 days. The two groups were comparable in their clinical and baseline characteristics. The clinical efficacy was similar in the two groups with only 2 (one in each group) clinical failures and all showing bacteriological eradication on subsequent blood culture. The time of defervescence was comparable in both groups (4.87 Fluconazole Prophylaxis against Fungal Colonization and Invasive Fungal Infection in Very Low Birth Weight Infants 2.33 vs 4.27 +/- 2.28 days, P = 0.308), with no relapse during 3 months follow up and no significant adverse effect. CP reduced the treatment cost by 33% in comparison to cefixime. Our study suggests CP is effective, safe and cheaper oral option for treatment of typhoid fever in children.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Shakur MS,Arzuman SA,Hossain J,Mehdi H,Ahmed Msubject
Has Abstractpub_date
2007-11-01 00:00:00pages
838-41issue
11eissn
0019-6061issn
0974-7559journal_volume
44pub_type
杂志文章,随机对照试验abstract::There is little published literature from the third World countries that described the factors influencing survival of babies with esophageal atresia. We analysed 25 consecutive neonates treated for esophageal atresia. The overall survival rate was 36%. All 4 babies in Waterston Group A, 37.5% in Group B, and 15.4% in...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract:: ...
journal_title:Indian pediatrics
pub_type: 评论,社论
doi:
更新日期:2018-11-15 00:00:00
abstract::A pilot study was undertaken to develop a feasible neonatal screening strategy for hemoglobinopathies. Isoelectric focusing using dried blood spots samples as a primary screening technique was standardized for the first time in India. The screened positives were confirmed by high performance liquid chromatography foll...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2011-02-01 00:00:00
abstract::India established the National Tuberculosis Control Project (NTCP) 50 years ago and re-designed it as Revised NTCP (RNTCP) 19 years ago. Tuberculosis (TB) control was beset with obstacles-BCG vaccination was found ineffective in TB control in 1979; human immunodeficiency virus began spreading in India since 1984 with ...
journal_title:Indian pediatrics
pub_type: 历史文章,杂志文章
doi:10.1007/s13312-013-0021-4
更新日期:2013-01-08 00:00:00
abstract::Two hundred and fifty eight newborn babies were studied for the presence of retinal hemorrhages between 1-3 days of birth. The overall incidence of retinal hemorrhages was found to be 18.9%. It was observed that the incidence of retinal hemorrhages was higher in unassisted vaginal deliveries than in assisted births. A...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-02-01 00:00:00
abstract::One hundred nine patients presenting with ambiguous genitalia over the past 10 years (year 1995 to 2004) to Pediatric Endocrine Service of our hospital were reviewed. On the basis of clinical and investigative evaluation like hormonal and biochemical estimations, imaging studies, karyotype and invasive techniques like...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVE:To compare the performance of respiratory rate and other clinical signs against pulse oximetry for predicting hypoxia in children with Severe pneumonia/Very severe disease as per Integrated Management of Neonatal and Childhood Illness (IMNCI) classification. DESIGN:Cross-sectional study. SETTING:Pediatric e...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-017-1163-6
更新日期:2017-09-15 00:00:00
abstract:OBJECTIVE:To compare lipid parameters between diabetics and controls and to study association between metabolic control and lipid profile. METHODS:Lipid profile and HbA1c were measured (n=80, 39 boys) in diabetic children [age 10.7(3.4) y] and 54 controls, tests repeated after 1 year (in 45 diabetics). RESULTS:Diabet...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-016-0787-2
更新日期:2016-01-01 00:00:00
abstract::Avian flu is affecting the poultry animals world over since first outbreak in 1997 in Hong Kong and has resulted in 92 human deaths and culling of more than 150 million poultry animals in Asia and Europe. The loss to the economy has also been enormous. 13 new countries, including India, reported occurrence of the dise...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2006-04-01 00:00:00
abstract::Current Medical training in India is generally didactic and pedagogical, and often does not systematically prepare newly graduated doctors to be competent, confident and compassionate. After much deliberation, the Medical Council of India (MCI) has recently introduced a new outcome-driven curriculum for undergraduate ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-10-15 00:00:00
abstract::Retinopathy of prematurity (ROP) is a leading cause of potentially avoidable childhood blindness worldwide. With improvement in neonatal care, more preterm infants are surviving with a resultant increase in the number of ROP cases. In low-middle income countries, the disease epidemiology is characterized by the occurr...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2016-11-07 00:00:00
abstract::Streptococcus viridans is usually considered to be nonpathogenic in healthy patients. Some strains become penicillin-resistant and cause life-threatening infections in immuno-compromised patients. We report an immunocompetent boy who had community-acquired S. viridans pneumonia that was resistant to penicillin. Clinic...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2012-04-01 00:00:00
abstract::The prevalence of vitamin A deficiency was estimated in 366 rural children in the age group of 1 to 15 years. In a systematically selected subsample of 90 children, the dietary intake of vitamin A was assessed. The prevalence of vitamin A deficiency signs ranged from 24.1 to 34.8%. The adequacy of dietary intake of vi...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1990-05-01 00:00:00
abstract::Eighty one pregnant women (20 +/- 2 weeks of gestation) were assessed for their nutritional status. They were divided into three groups; Group I women (n = 30) were given 200 mg ferrous sulphate (FeSO4) tablet per day for 15 weeks, Group II women (n = 25) were given FeSO4 tablets along with 2,000,000 IU of vitamin A a...
journal_title:Indian pediatrics
pub_type: 临床试验,杂志文章
doi:
更新日期:1995-08-01 00:00:00
abstract:BACKGROUND:Neuroschistosomiasis is an uncommonly reported disease. CASE CHARACTERISTICS:An adolescent Indian boy residing in Kenya presented with headache, visual symptoms and seizures, with MRI showing space-occupying lesions in the occipital lobe and cerebellum. OBSERVATION:Brain biopsy was diagnostic of neuro-schi...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2018-11-15 00:00:00
abstract::Cord problems at birth were prospectively studied in 12,000 singleton deliveries, of which 258 (2.15%) babies had cord abnormalities. Nearly 32% of these cases had fetal distress and 20.5% had 1 minute Apgar score less than 6. Of the various cord problems nuchal cord was noted in 79.1%, cord prolapse in 12.4% and true...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-03-01 00:00:00
abstract::Twenty-six neonates were diagnosed to have acinetobacter sepsis during 1986-90, representing 6.5% of all cases of bacteriologically proven sepsis. Of these 19 neonates were low birth weight (LBW) 12 were small for gestational age (SGA). Nineteen neonates had early-onset sepsis. The male to female ratio was 9:17. The h...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1993-12-01 00:00:00
abstract::The study aimed to explore the perception and knowledge-gain of undergraduate medical students during the Medical Council of India-mandated one month foundation course in August, 2019. A total of 129 consenting students who underwent the foundation course were enrolled and their feedback collected using an email-based...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-03-15 00:00:00
abstract:OBJECTIVE:To assess the epidemiological and clinical characteristics of pediatric inpatients with COVID-19, early in the pandemic. METHODS:Clinical and laboratory profile and outcomes were studied for children (aged 1 month - 18 years) presenting between 1 April, 2020 and 20 May, 2020 with positive nasopharyngeal swab...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-10-15 00:00:00
abstract::Marfan syndrome rarely presents with peripheral artery and pulmonary artery aneurysms. We are presenting a case of a fifteen-year-old boy who presented to us with progressive lower abdominal pulsatile swelling with bruit in the right inguinal region for one month. He had typical marfanoid habitus, though there was no ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2013-05-08 00:00:00
abstract::Two hundred and forty four girls with different hemoglobin levels were selected, of which forty-one were non-anemic. The rest were graded as mildly, moderately or severely anemic and supplemented with 60 mg of iron daily or twice weekly for twelve weeks. There was no significant difference in the increase in hemoglobi...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of vitamin D and calcium supplementation for osteoprotection in thalassemia. METHODS:29 children (age 2-12 y) were supplemented with oral vitamin D (1000 IU/d) and calcium (500 mg/d) for 1 year. The dual energy X-ray absorptiometry (DXA) was done to assess bone mineral content at basel...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2019-04-15 00:00:00
abstract::The morbidity pattern and nutritional profile was evaluated of school children who resided around Mosaboni Copper Mines and in surrounding villages of Ghatsila subdivision in Singhbhum district of Bihar State, India. A total of 1424 school children (816 boys and 608 girls) between 5-17 years old were studied. Children...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-06-01 00:00:00
abstract:OBJECTIVE:To assess yield of MECP2 gene sequence variations analysis and large deletions in suspected cases of Rett syndrome. DESIGN:Descriptive study. SETTING:Tertiary-care medical genetics center. PATIENTS:Girls with neuroregression, postnatal microcephaly and signs and symptoms suggestive of classical and atypica...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2018-06-15 00:00:00
abstract:OBJECTIVE:To provide tribe- specific child mortality rates and health indicators from selected states in India. METHODS:We used Census 2011 data and Coale Demney methodology to estimate the infant mortality rate (IMR), under-five mortality rate (U5MR) and expectation of life at birth (LEB) for 123 tribes of selected s...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2021-01-15 00:00:00
abstract::The prevalence of Attention deficit hyperactivity disorder was estimated in 500 adolescents using Conners' parents and teachers rating scales. Thirty six (7.2%) adolescents had positive scores on both the scales. The parents and teachers also completed a Diagnostic and Statistical Manual-IV based questionnaire which s...
journal_title:Indian pediatrics
pub_type: 信件
doi:10.1007/s13312-014-0350-y
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:Glycogen storage disease type VI (GSD-VI) presents with failure to thrive and also fibrosis in some cases, without cirrhosis. CASE CHARACTERISTICS:2½-year-old girl presented with short stature, transaminase elevation and significant fibrosis, suggesting GSD-III. OBSERVATION:A pathogenic mutation in PYGL ge...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-017-1174-3
更新日期:2017-09-15 00:00:00
abstract::Transfusion-related acute lung injury is a rare form of acute respiratory distress syndrome of possible immune etiology that develops immediately after a blood product transfusion. Clinicians need to be aware of this condition as prompt recognition and supportive management can prevent unwanted morbidity and mortality...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2012-02-01 00:00:00
abstract::Patent ductus arteriosus (PDA) is a major morbidity in preterm infants, especially in extremely premature infants less than 28 weeks. The clinical signs and symptoms of PDA in preterm infants are non specific and insensitive for making an early diagnosis of significant ductal shunting. Functional echocardiography is e...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s13312-011-0062-5
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:(i) To assess the severity of Iodine Deficiency Disorders (DD) in Baroda and Dang Districts of Gujarat, using biochemical prevalence indicators of IDD; and (ii) To establish a biochemical baseline, in a sub-sample of the large population of Gujarat, that could be used to monitor the effectiveness of iodine re...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2001-03-01 00:00:00