Abstract:
OBJECTIVE:(i) To assess the severity of Iodine Deficiency Disorders (DD) in Baroda and Dang Districts of Gujarat, using biochemical prevalence indicators of IDD; and (ii) To establish a biochemical baseline, in a sub-sample of the large population of Gujarat, that could be used to monitor the effectiveness of iodine replacement program. METHODS:1,363 children (<1-15 years) were studied and data was collected on dietary habits, anthropometric and biochemical parameters such as height, weight and urinary iodine (UI) and blood TSH respectively. BSA and BMI were calculated. Drinking water and salt were analyzed for iodine content. RESULTS:Median true urinary iodine was 65 microg/I (interquartile-range 38-108). Mean TSH was 2.08 mU/1 (SD +/- 2.06) and 6% of the studied population had whole blood TSH values > 5 mU/1. Females from both districts were affected more by iodine deficiency as evidenced by lower true urinary iodine and higher mean TSH levels. The interfering substances were significantly higher in Baroda boys and Dang girls as compared to their counterparts (< 0.001). Boys were more malnourished than girls as evidenced by lower BMI. Dang district was more severely affected by IDD as compared to Baroda. Drinking water in Dang district was lacking in iodine content. Iodine in salt varied at around 7 to 2000 PPM. CONCLUSIONS:IDD is a public health problem in Gujarat. Baroda district is a new pocket of IDD. Dang district is the worse affected. The expression of IDD in these two districts of Gujarat revealed interplay of multiple factors.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Brahmbhatt SR,Fearnley RA,Brahmbhatt RM,Eastman CJ,Boyages SGkeywords:
subject
Has Abstractpub_date
2001-03-01 00:00:00pages
247-55issue
3eissn
0019-6061issn
0974-7559journal_volume
38pub_type
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:
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pub_type: 杂志文章
doi:
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journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
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pub_type: 杂志文章,评审
doi:
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pub_type: 杂志文章,评审
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doi:
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pub_type: 杂志文章
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journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,随机对照试验
doi:
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pub_type: 杂志文章
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pub_type: 杂志文章,评审
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