Abstract:
:Sixty children with acute bacterial meningitis (ABM) were prospectively studied for their serum sodium values and cerebrospinal fluid (CSF), serum and urinary osmolality. The results have been compared with 20 age and nutritionally matched controls. Even though mean serum osmolality (283.2 +/- 13.84 mOsm/kg) and serum sodium levels (130.5 +/- 8.15 mEq/L) were significantly lower in ABM in comparison to controls (p < 0.05 and < 0.001, respectively), the overall mean CSF osmolality in patients with ABM (282.5 +/- 12.3 mOsm/kg) was not significantly different as compared to controls (288.2 +/- 7.89 mOsm/kg). As expected, cases of ABM with syndrome of inappropriate secretion of antidiuretic hormone (SIADH) had significantly lower CSF osmolality (272 +/- 9.42 mOsm/kg) as compared to those without SIADH (288.5 +/- 9.34 mOsm/kg) and controls (288.2 +/- 7.89 mOsm/kg). However, our observations indicate that whereas the mean CSF osmolality was lower than the serum osmolality in the control group as well as in ABM without SIADH, it was greater than serum osmolality in ABM with SIADH (p < 0.05). Our results suggest that in the presence of SIADH, hypo-osmolality of serum may eventually result in hypo-osmolality of CSF, but the fall in CSF osmolality is not of the same degree as that of serum. Low CSF osmolality was observed to be associated with an unfavorable prognosis (p < 0.05).
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Singh BS,Patwari AK,Deb Msubject
Has Abstractpub_date
1993-10-01 00:00:00pages
1193-7issue
10eissn
0019-6061issn
0974-7559journal_volume
30pub_type
杂志文章abstract:OBJECTIVE:To describe the utility of flexible fiberoptic bronchoscopy for the diagnosis and management in the neonatal ICU. METHODS:A retrospective, medical chart review was conducted in neonates who underwent flexible fiberoptic bronchoscopy over a period of 7 years. Besides demographic data and diagnostic findings, ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2019-07-15 00:00:00
abstract:OBJECTIVE:To find out the degree of current undernutrition in rural reproductive age women. SETTING:49 villages of two adjoining rural blocks of Varanasi. METHODS:6130 non-pregnant and non-lactating rural women in the age group 18-45 year were studied for sociodemographic characteristics and anthropometry, i.e., weig...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1998-10-01 00:00:00
abstract::Massive open online courses (MOOCs) are currently the buzz word in the field of e-learning. By definition, MOOCs are massive courses considering the number of participants enrolled across the globe per course, are open accessed, and are available online. MOOCs have evolved along the trajectory of correspondence course...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2019-06-15 00:00:00
abstract:OBJECTIVE:To describe the clinical characteristics and outcome of Indian children infected with 2009 H1N1 influenza virus. STUDY DESIGN:Retrospective chart review. SETTING:Outpatient department and hospitalized patients in a tertiary care hospital. METHODS:Clinical details of 85 children (positive for the 2009 H1N1 ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-011-0085-y
更新日期:2011-05-01 00:00:00
abstract::India established the National Tuberculosis Control Project (NTCP) 50 years ago and re-designed it as Revised NTCP (RNTCP) 19 years ago. Tuberculosis (TB) control was beset with obstacles-BCG vaccination was found ineffective in TB control in 1979; human immunodeficiency virus began spreading in India since 1984 with ...
journal_title:Indian pediatrics
pub_type: 历史文章,杂志文章
doi:10.1007/s13312-013-0021-4
更新日期:2013-01-08 00:00:00
abstract:OBJECTIVE:To assess the effects of delayed cord clamping (DCC) on hemoglobin (Hb), mean corpuscular volume (MCV) and ferritin level in infants 2 months or older. EVIDENCE ACQUISITION:Meta-analysis of randomized control trials searched systematically from PubMed, Cochrane and Web of science. Trials published from Jan 1...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-09-15 00:00:00
abstract:CONTEXT:Cryptosporidium spp. is a zoonotic infection, now being recognized as a significant cause of diarrhea in both immunocompetent and immunocompromised hosts. However, there still exist significant knowledge gaps in its estimated global burden, epidemiology, diagnosis and management. EVIDENCE ACQUISITION:A semi-sy...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s13312-017-1093-3
更新日期:2017-04-15 00:00:00
abstract::Atypical celiac disease (ACD) presenting in childhood has rarely been documented from India. The present retrospective study analyzed features of atypical celiac disease over a 5-year period. Patients were diagnosed to have Celiac Disease (CD) as per the standard ESPGHAN criteria. The biochemical and hematological par...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2004-08-01 00:00:00
abstract::There is a large child work force in India reported to be about 40 million. Child labor is being regarded as a form of modern slavery, as children are forced to work or have no choice to refuse work. Children are employed in a variety of occupations, many of which are hazardous. Exposure to machinery, pesticides, dust...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2019-08-15 00:00:00
abstract:Context:Infantile colic is self-limiting condition but it can be a cause of anxiety for parents and challenge for doctors. The challenge for the doctors lies in correct identification of the condition and appropriate management. The objective of this review article is to summarize the pathophysiology, treatment options...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2018-11-15 00:00:00
abstract:OBJECTIVE:To determine the clinical utility of serum neutrophil gelatinase-associated lipocalin (NGAL) as an early marker of acute kidney injury in asphyxiated neonates with hypoxic ischemic encephalopathy (HIE). DESIGN:Cohort study. SETTINGS:National Intensive Care Unit of Maternity Hospital, Ain Shams University, C...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-013-0153-6
更新日期:2013-05-08 00:00:00
abstract::Clinical and hematological data of 9 cases with factor XIII deficiency is highlighted. The age at first bleed ranged from 3 days of life to 1 year. Seven of these 9 cases had bleeding from the umbilicus, 3 had recurrent subcutaneous and muscle hematomas, while 4 cases had CNS bleeds of which 3 expired. Routine coagulo...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:1992-07-01 00:00:00
abstract::We report a 71/2-year-boy with disseminated systemic cryptococcosis. Although other species have been incriminated, this appears to be the first report of Cryptococcus humicolus. The child was HIV negative. He was treated with amphotericin B and fluconazole with intensive supportive care. The child responded after 6 w...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVE:To examine the association between hematological indices and serum uric acid in adolescents with hyperuricemia. METHODS:10-year retrospective cohort study of 607 patients with hyperuricemia registered with the Pediatric Nephrology Department. RESULTS:There was a statistically significant positive correlatio...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-014-0547-0
更新日期:2014-12-01 00:00:00
abstract::The objectives of this study were to evaluate whether a newborn or a neonate is capable of responding immunologically after BCG vaccination and to find out if this immunity persists for one year. Normal infants aged between 0 days-3 months brought to immunization centre were included in the study. In vitro leukocyte m...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
abstract::The skinfold thickness (SFT) was measured in 750 Punjabi newborns at triceps and subscapular sites using a Harpenden's Caliper. It was correlated with various maternal and neonatal factors. SFT increased with increasing gestation but showed a decline after 40 weeks. There was a positive correlation of SFT with birth w...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract::Shwachman-Diamond Syndrome (SDS) is a rare inherited disorder characterized by pancreatic insufficiency, bone marrow dysfunction and skeletal abnormalities. It is the most common cause of pancreatic insufficiency in children after cystic fibrosis. We report a child with classical SDS who presented to us predominantly ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-012-0138-x
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVE:To describe a novel wrist deformity in b-thalassemia major patients, and their radiographic and magnetic resonance imaging findings. METHODS:30 patients with b-thalassemia major who were noticed to have ulnar deviation at wrist joint were evaluated for previous history of medications, serum ferritin levels, ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2019-01-15 00:00:00
abstract:OBJECTIVE:To identify the factors influencing brain injury in infants with congenital heart disease (CHD) after cardiac surgery. METHODS:This retrospective study investigated 103 infants with CHD undergoing cardiac surgery between January 2013 and February 2016. Pre- and postoperative amplitude-integrated electroencep...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-02-15 00:00:00
abstract::Fifty eight (16%) of the 362 patients, who reported to Dermatology and STD Department with symptoms pertaining to their genitourinary system were below 14 years of age. Fifty four (93.1%) of these children belonged to families of lower socio-economic strata. All the children were slum dwellers and none of them had stu...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::This retrospective analysis documents the usefulness of fiberoptic bronchoscopy in finding the etiology of 56 cases of unresolved atelectasis in infancy, over a two year period (June 2005 to May 2007). Fiberoptic bronchoscopy identified the etiology leading to a revised diagnosis and change in management strategy in 3...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-010-0134-y
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:To assess the glycometabolic function in chronically transfused patients of beta- thalassemia major in terms of glucose tolerance, insulin secretion, insulin resistance index, and beta cell function index and to determine their relationship with clinical and biochemical profile. METHODS:30 homozygous thalass...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2006-05-01 00:00:00
abstract::We report a 6 year old female child, who presented with history of right sided recurrent headache for four months. On diagnostic nasal endoscopy, a metallic foreign body was seen impacted between superior turbinate, middle turbinate and nasal septum which was removed using pediatric nasal endoscope. Following removal,...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2011-08-01 00:00:00
abstract::Pulmonary manifestations of sarcoidosis are common and may be initially confused with other common diseases like tuberculosis. We report an 11 yr old girl who presented with chronic cough, low grade fever, recent exposure to tuberculosis and hilar lymphadenopathy. She was provisionally diagnosed as pulmonary tuberculo...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2007-08-01 00:00:00
abstract::The year 2013 marks 50 years of both newborn screening and the Indian Academy of Pediatrics. India has seen a lot of change in terms of motivation, evolution and implementation of newborn screening as pilot projects for few disorders. Facilities for implementing screening using tandem mass spectrometry or what is term...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-013-0187-9
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the short term clinical effects of delayed cord clamping in preterm neonates. DESIGN:Randomized controlled trial. SETTING:A tertiary care neonatal unit from October 2013 to September 2014. PARTICIPANTS:78 mothers with preterm labor between 27 to 316/7 weeks gestation. INTERVENTION:Early cord c...
journal_title:Indian pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s13312-017-1011-8
更新日期:2017-02-15 00:00:00
abstract::Yunis-Varon syndrome is a rare, autosomal recessive syndrome characterized by growth retardation, defective growth of the cranial bones along with complete or partial absence of the clavicles (cleidocranial dysplasia), characteristic facial features, and/or abnormalities of the fingers and/or toes. ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2005-04-01 00:00:00
abstract::The forced vital capacity, forced expiratory volume in one second, peak expiratory flow, mid-expiratory flow and maximum voluntary ventilation was measured in 632 healthy, normal children from Metropolitan city of Bombay using computerized spirometer. The children were between age range 6 years to 15 years and belong ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1995-02-01 00:00:00
abstract:OBJECTIVE:To study the etiological profile and patterns of clinical presentation of nephrocalcinosis. METHODS:In this observational study, patients 18 years or younger, referred to the pediatric nephrology clinic with nephrocalcinosis were evaluated for etiology. Symptoms/signs at presentation, estimated glomerular fi...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-05-15 00:00:00
abstract:OBJECTIVE:We examined associations of different adiposity measures with cortisol responses during the Trier Social Stress Test for children (TSST-C). DESIGN:Descriptive study. SETTING:Holdsworth Memorial Hospital, Mysore, India. PARTICIPANTS:Adolescents aged 13.5y from a birth cohort were recruited (N=269, 133 boys)...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2018-02-15 00:00:00