Peri- and Post-operative Amplitude-integrated Electroencephalography in Infants with Congenital Heart Disease.

Abstract:

OBJECTIVE:To identify the factors influencing brain injury in infants with congenital heart disease (CHD) after cardiac surgery. METHODS:This retrospective study investigated 103 infants with CHD undergoing cardiac surgery between January 2013 and February 2016. Pre- and postoperative amplitude-integrated electroencephalography (aEEG) recordings were assessed for background pattern, sleep-wake cycle pattern and seizure activity. Logistic regression model was used to determine the influencing factors of brain injury. RESULTS:Pre-operatively, most infants in our study exhibited a normal background pattern, with 16.5% showing discontinuous normal voltage, whereas this pattern was observed in only 7.8% of infants postoperatively. The improvement in background pattern after surgery was significant (P<0.05) in infants at no more than 39 weeks of gestational age. Infants with postoperative sepsis or severe postoperative infection were prone to show a worse sleep-wake cycle pattern after heart surgery. CONCLUSIONS:The improvement in brain function of infants with CHD after cardiac surgery was associated with the gestational age and postoperative infection.

journal_name

Indian Pediatr

journal_title

Indian pediatrics

authors

Gui J,He S,Zhuang J,Sun Y,Liu Y,Liang S,Chen C,Ren Y,Wang B,Chen J

subject

Has Abstract

pub_date

2020-02-15 00:00:00

pages

133-137

issue

2

eissn

0019-6061

issn

0974-7559

journal_volume

57

pub_type

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