Congenital factor XIII deficiency.

Abstract:

:Clinical and hematological data of 9 cases with factor XIII deficiency is highlighted. The age at first bleed ranged from 3 days of life to 1 year. Seven of these 9 cases had bleeding from the umbilicus, 3 had recurrent subcutaneous and muscle hematomas, while 4 cases had CNS bleeds of which 3 expired. Routine coagulogram was normal, while clot solubility in 5 molar urea solution was abnormal in all cases. Factor XIII assay was not done in any. Patients were treated with plasma transfusion during episodes of bleeding. No patient received plasma transfusion as prophylactic therapy. The cumulative Indian data so far documented, inclusive of this series, shows a very high incidence of CNS bleeds (33%) in patients with this inherited coagulation disorder.

journal_name

Indian Pediatr

journal_title

Indian pediatrics

authors

Merchant RH,Agarwal BR,Currimbhoy Z,Pherwani A,Avasthi B

keywords:

subject

Has Abstract

pub_date

1992-07-01 00:00:00

pages

831-6

issue

7

eissn

0019-6061

issn

0974-7559

journal_volume

29

pub_type

杂志文章,评审
  • Maternal Overt Hypothyroidism and Neurobehavioral Outcome of Neonates: A Cohort Study from an Iodine-deficient Area of Northern India.

    abstract:OBJECTIVE:To study the relation between maternal overt hypothyroidism and neurodevelopmental outcome of neonates in iodine-deficient region of Northern India (Kashmir Valley). DESIGN:Prospective cohort study. SETTING:Endocrinology department of a tertiary-care hospital. PARTICIPANTS:82 hypothyroid pregnant women wer...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-015-0733-8

    authors: Ganaie MA,Charoo BA,Sofi RA,Ahmed A,Bhat JI

    更新日期:2015-10-01 00:00:00

  • Attention deficit hyperactivity disorder in adolescent school children.

    abstract::The prevalence of Attention deficit hyperactivity disorder was estimated in 500 adolescents using Conners' parents and teachers rating scales. Thirty six (7.2%) adolescents had positive scores on both the scales. The parents and teachers also completed a Diagnostic and Statistical Manual-IV based questionnaire which s...

    journal_title:Indian pediatrics

    pub_type: 信件

    doi:10.1007/s13312-014-0350-y

    authors: Juneja M,Sairam S,Jain R

    更新日期:2014-02-01 00:00:00

  • Antimicrobial Stewardship in Pediatrics: An Indian Perspective.

    abstract::Antimicrobial resistance has become a global menace. As the resistance patterns and numbers are progressively increasing, it has become a major cause of morbidity and mortality in hospitalized patients, especially children. Efforts are being put world-over to curb the rising resistance by various means, especially by ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-016-0839-7

    authors: Bedi N,Gupta P

    更新日期:2016-04-01 00:00:00

  • Detection of cryptosporidium oocysts in acute diarrheal stools.

    abstract::Three hundred and fifty stool samples from patients with acute diarrhea and 30 samples from normal healthy controls were examined for the presence of various parasitic and bacterial enteropathogens by conventional techniques. Cryptosporidium oocysts were detected in 15 out of 350 (4.3%) fecal samples. In 10 cases (2.9...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Uppal B,Natarajan R

    更新日期:1991-08-01 00:00:00

  • Idiopathic hypereosinophilic syndrome--unusual presentation.

    abstract::A case of idiopathic hypereosinophilic syndrome who had an unusual presentation in the form of pericardial effusion is being presented here. The child initially responded to corticosteroids but could not maintain normal eosinophil counts on tapering of steroids. Therefore he was put on hydroxyurea and low dose of ster...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Jain AK,Dubey AP,Sudha S

    更新日期:2004-01-01 00:00:00

  • A New Combined Vaccine Against Measles, Mumps, Rubella and Varicella in India.

    abstract::A quadrivalent MMRV (measles-mumps-rubella-varicella) combination vaccine has recently been launched in India. This vaccine is highly immunogenic, with seroconversion rates against all antigens reaching 96.6-100% at 42 to 56 days after the second vaccine dose in unvaccinated children or in those previously vaccinated ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s13312-017-1209-9

    authors: Shah N,Parikh R,Casabona G,Kolhapure S

    更新日期:2017-12-15 00:00:00

  • Randomized comparison of a dry powder inhaler and metered dose inhaler with spacer in management of children with asthma.

    abstract:OBJECTIVE:Comparison of the clinical efficacy of a transparent, DPI (transparent Rotahaler) with MDI and spacers in childhood asthma. DESIGN:Open, randomized, crossover trial. SETTINGS:Out patient clinic of a referral pediatric center. METHODS:Thirty (mean 6.1 +/-2.7 years) children with moderate persistent asthma w...

    journal_title:Indian pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Singh M,Kumar L

    更新日期:2001-01-01 00:00:00

  • Editorial policies of MEDLINE indexed Indian journals on clinical trial registration.

    abstract::30 MEDLINE indexed Indian journals publishing clinical trials were identified and their editorial policies on trial registration were assessed. Trial registration number was required in 9 journals (30%).16 journals (53.33%) encouraged adherence to the CONSORT Statement, while 22 (73.33%) mentioned ICMJE Guidelines. ...

    journal_title:Indian pediatrics

    pub_type: 信件

    doi:10.1007/s13312-013-0092-2

    authors: Bhaumik S,Biswas T

    更新日期:2013-03-01 00:00:00

  • Is C-reactive protein level useful in differentiating infected from uninfected neonates among those at risk of infection?

    abstract:OBJECTIVE:To document effects of intrapartum risk factors for early onset sepsis (EOS) on CRP levels in neonates and to assess the suitability of this test in diagnosing EOS. DESIGN:Cohort study. SETTING:Labour and post natal wards in a tertiary level teaching hospital in India. SUBJECTS:250 neonates at risk of deve...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Mathai E,Christopher U,Mathai M,Jana AK,Rose D,Bergstrom S

    更新日期:2004-09-01 00:00:00

  • Birth asphyxia and neurodevelopmental outcome.

    abstract::Thirty six neonates with severe birth asphyxia (Apgar score less than or equal to 3 at 1 min), 32 with moderate birth asphyxia (Apgar score 4 to 6 at 1 min) and 35 controls (Apgar score greater than or equal to 7 at 1 min) matched for weight and gestation were followed up prospectively for neurodevelopmental outcome. ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Deorari AK,Paul VK,Singh M

    更新日期:1989-08-01 00:00:00

  • Quality of life in symptomatic HIV infected children.

    abstract::We conducted a case control study to compare the quality of life (QOL) in 40 cases of HIV infected children and 40 demographically matched controls with other chronic ailments at a referral hospital in Northern India. Quality of life among HIV infected children was significantly better in psychosocial (P=0.008), emoti...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-013-0300-0

    authors: Gupta M,Nanda S,Kaushik JS

    更新日期:2013-12-01 00:00:00

  • Spectrum of atypical celiac disease in North Indian children.

    abstract::Atypical celiac disease (ACD) presenting in childhood has rarely been documented from India. The present retrospective study analyzed features of atypical celiac disease over a 5-year period. Patients were diagnosed to have Celiac Disease (CD) as per the standard ESPGHAN criteria. The biochemical and hematological par...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Puri AS,Garg S,Monga R,Tyagi P,Saraswat MK

    更新日期:2004-08-01 00:00:00

  • Standing up for Science.

    abstract:: ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Soans ST

    更新日期:2018-12-15 00:00:00

  • Association between Helicobacter pylori Infection and Iron Deficiency Anemia in School-aged Iranian Children.

    abstract:OBJECTIVES:To find the relationship between Helicobacter pylori infection and iron deficiency anemia in school-aged children. METHODS:71 children with dyspepsia, epigastric and vague abdominal pain attending a tertiary medical center in Iran underwent upper gastrointestinal endoscopy and were investigated for H. Pylor...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Zahmatkeshan M,Karimi M,Geramizadeh B,Eslaminasab S,Esmailnejad A,Safarpour AR

    更新日期:2019-05-15 00:00:00

  • Adolescent violence exposure, gender issues and impact.

    abstract::Youth violence is a growing problem worldwide. Research on adolescent violence in India is limited. Fifteen hundred high school students were investigated to study the prevalence and demographic characteristics of witnesses, victims and perpetrators of violence and to see the impact of violence exposure on their psych...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Munni R,Malhi P

    更新日期:2006-07-01 00:00:00

  • Hematopoietic stem cell transplantation in children with genetic defects.

    abstract::Seventeen children (mean age: 7.2 years) with genetic defects involving hematopoietic cell production or function, underwent 19 allogeneic stem cell transplantations from HLA identical siblings. Twelve children were suffering from thalassemia major; 2 from Diamond Blackfan anemia; 2 from Fanconi anemia and 1 from cong...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Nair V,Das S,Sharma A

    更新日期:2009-03-01 00:00:00

  • Retinopathy of Prematurity: AIIMS, New Delhi Experience.

    abstract::Retinopathy of prematurity (ROP) is a leading cause of potentially avoidable childhood blindness worldwide. With improvement in neonatal care, more preterm infants are surviving with a resultant increase in the number of ROP cases. In low-middle income countries, the disease epidemiology is characterized by the occurr...

    journal_title:Indian pediatrics

    pub_type: 杂志文章,评审

    doi:

    authors: Sivanandan S,Chandra P,Deorari AK,Agarwal R

    更新日期:2016-11-07 00:00:00

  • Guillain-Barre syndrome following dengue fever.

    abstract::Guillain-Barre syndrome is a post infectious polyradiculoneuropathy. It is equally prevalent in both the adult and the pediatric populations. Guillain-Barre syndrome following dengue fever is not a classically described entity and has not been reported in children. ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Sulekha C,Kumar S,Philip J

    更新日期:2004-09-01 00:00:00

  • Flexible Fiberoptic Bronchoscopy Directed Interventions in Neonatal Intensive Care Unit.

    abstract:OBJECTIVE:To describe the utility of flexible fiberoptic bronchoscopy for the diagnosis and management in the neonatal ICU. METHODS:A retrospective, medical chart review was conducted in neonates who underwent flexible fiberoptic bronchoscopy over a period of 7 years. Besides demographic data and diagnostic findings, ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Sachdev A,Chhawchharia R,Gupta D,Gupta N

    更新日期:2019-07-15 00:00:00

  • Treatment of nephrotic syndrome.

    abstract::There are well defined therapeutic protocols for childhood nephrotic syndrome. Appropriate therapy helps in minimizing side effects besides decreasing referrals to tertiary care centres. We have analysed the appropriateness of therapy of primary care physicians in 111 children with nephrotic syndrome referred to our I...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Gulati S,Kher V,Elhence R,Kumar P,Sharma RK,Gupta A

    更新日期:1994-02-01 00:00:00

  • Undergraduate Medical Students' Experience with Foundation Course at a Public Medical College in India.

    abstract::The study aimed to explore the perception and knowledge-gain of undergraduate medical students during the Medical Council of India-mandated one month foundation course in August, 2019. A total of 129 consenting students who underwent the foundation course were enrolled and their feedback collected using an email-based...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Dabas A,Verma D,Kumar D,Mishra D

    更新日期:2020-03-15 00:00:00

  • Early Initiation of Steroid-sparing Drugs in Idiopathic Pulmonary Hemosiderosis.

    abstract::Idiopathic pulmonary hemosiderosis is conventionally treated with steroids, prolonged usage of which maybe deleterious and disease often recurs on tapering. We initiated hydroxy-chloroquine and azathioprine early in treatment along with steroids in seven children with idiopathic pulmonary hemosiderosis, and observed t...

    journal_title:Indian pediatrics

    pub_type: 信件

    doi:

    authors: Pal P,De H,Giri PP,Ganguly N,Mandal A

    更新日期:2019-01-15 00:00:00

  • Oscillometric Blood Pressure in Indian School Children: Simplified Percentile Tables and Charts.

    abstract:BACKGROUND:Data on blood pressure recorded by oscillometric method is limited. OBJECTIVE:To develop simplified tables and charts of blood pressure recorded by oscillometric method in children. DESIGN:Cross-sectional. SETTING:Ballabhgarh, Haryana. PARTICIPANTS:Healthy school-children. MAIN OUTCOME MEASURES:Blood pr...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-015-0749-0

    authors: Narang R,Saxena A,Ramakrishnan S,Dwivedi SN,Bagga A

    更新日期:2015-11-01 00:00:00

  • Efficacy of twice weekly iron supplementation in anemic adolescent girls.

    abstract::Two hundred and forty four girls with different hemoglobin levels were selected, of which forty-one were non-anemic. The rest were graded as mildly, moderately or severely anemic and supplemented with 60 mg of iron daily or twice weekly for twelve weeks. There was no significant difference in the increase in hemoglobi...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Shobha S,Sharada D

    更新日期:2003-12-01 00:00:00

  • Acute renal failure due to acute tubulointerstitial nephritis.

    abstract::Acute interstitial nephritis (AIN) should be ruled out in children with unexplained acute renal failure. We present a 4 1/2 year old girl who presented with oliguric acute renal failure preceded by a febrile illness. Renal histopathology revealed features of drug induced AIN. She recovered with dialysis, other support...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Premalatha R,Phadke KD,Gag I,Rout P

    更新日期:2003-04-01 00:00:00

  • Epidemiological and Clinical Characteristics of COVID-19 in Indian Children in the Initial Phase of the Pandemic.

    abstract:OBJECTIVE:To assess the epidemiological and clinical characteristics of pediatric inpatients with COVID-19, early in the pandemic. METHODS:Clinical and laboratory profile and outcomes were studied for children (aged 1 month - 18 years) presenting between 1 April, 2020 and 20 May, 2020 with positive nasopharyngeal swab...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Sarangi B,Reddy VS,Oswal JS,Malshe N,Patil A,Chakraborty M,Lalwani S

    更新日期:2020-10-15 00:00:00

  • Age independent anthropometric index for identifying undernourished children in the age group 5-10 years.

    abstract::An age-independent anthropometric index to identify undernourished children in the age group of 5-10 years is described. Employing a mathematical approach (linear regression analysis) on data from 238 children, the index was derived to be wt/(ht)2. Employing this index, a classification rule for identifying the undern...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Ramakrishnan R,Rao TV,Prasad GP

    更新日期:1992-06-01 00:00:00

  • Occupational morbidity among children employed in brassware industry.

    abstract::Fifty seven male children between ages of 10-16 years engaged in the brassware industry at Moradabad in Northern India were studied for occupational morbidity. The finding were compared with those obtained in the children (n = 29) engaged in other ancillary units which did not involve exposure to the metal fumes and d...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Bihari V,Rastogi SK,Gupta BN,Husain T,Mathur N,Mahendra PN,Srivastava S,Garg N

    更新日期:1992-02-01 00:00:00

  • Abdominal tuberculosis in children: experience over a decade.

    abstract::This presentation deals with 110 surgically proven cases of abdominal tuberculosis in the pediatric age group. The protean clinical profiles and complications of the disease entity made the clinical diagnosis difficult; the investigations were also found non-pathognomonic. The most common type of pathology seen was ad...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Sharma AK,Agarwal LD,Sharma CS,Sarin YK

    更新日期:1993-09-01 00:00:00

  • Informed consent in pediatric practice.

    abstract::Informed consent is a communication process of providing the patient/parents/guardians with relevant information regarding the treatment and the diagnosis, so that they can make informed decisions. The process of informed consent in pediatric patients is not well understood. The amount of information to be disclosed i...

    journal_title:Indian pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s13312-010-0173-4

    authors: Kaushik JS,Narang M,Agarwal N

    更新日期:2010-12-01 00:00:00