Abstract:
:Thirty six neonates with severe birth asphyxia (Apgar score less than or equal to 3 at 1 min), 32 with moderate birth asphyxia (Apgar score 4 to 6 at 1 min) and 35 controls (Apgar score greater than or equal to 7 at 1 min) matched for weight and gestation were followed up prospectively for neurodevelopmental outcome. Fetal distress occurred more frequently in babies with severe birth asphyxia when compared to controls (p less than 0.05). Six neonates with severe birth asphyxia had abnormal neurological signs such as delayed sucking, hypo or hypertonia, apneic spell or seizures. Of these, only two had delayed developmental milestones (Developmental Quotient less than 70) and features of cerebral palsy. Both of these babies developed seizures during first 24 hours, did not suck and required gavage feeding. The study highlights the fact that a vast majority of survivors of birth asphyxia enjoy good quality of life thus emphasizing the need for vigorous management of asphyxiated babies at birth.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Deorari AK,Paul VK,Singh Msubject
Has Abstractpub_date
1989-08-01 00:00:00pages
793-9issue
8eissn
0019-6061issn
0974-7559journal_volume
26pub_type
杂志文章abstract:BACKGROUND:GM1 gangliosidosis is a disorder due to GLB1 gene mutation. CASE CHARACTERISTICS:A 4-yr-old boy with neuroregression and optic atrophy with periventricular hyperintensity on magnetic resonance imaging. OUTCOME:Beta galactosidase enzyme activity was low which was confirmed by GLB1 sequencing. MESSAGE:We hi...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-015-0593-2
更新日期:2015-02-01 00:00:00
abstract::We observed a significant fall in neonatal mortality in babies weighing less than 2 kg during 1986 as compared to 1973 (7.94% vs 12.88%; p less than 0.005), and in preterm babies the mortality fell from 26.88 to 11.5% (p less than 0.001) during 1986. This was achieved despite 2-3 fold increase in the high risk babies ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-03-01 00:00:00
abstract:BACKGROUND:High bilirubin level is toxic to developing brain and auditory system but the current debate surrounds the toxicity of bilirubin in healthy term infants. METHODS:Longitudinal observational study to find BERA abnormalities in term newborns with isolated hyperbilirubinemia of 20 mg/dL and more and to follow u...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-014-0346-7
更新日期:2014-02-01 00:00:00
abstract::The incidence and the factors that influence twinning were studied in six villages of Dholka Taluka, a rural field training centre. The twinning rate was 10.10 per 1000 maternities. The monozygotic and dizygotic twinning rates were 4.53 and 5.56, respectively by applying Weinberg's differential formula. In three fourt...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1990-03-01 00:00:00
abstract::A 12-year-old boy had undergone total gastrectomy for gastric volvulus with subsequent severe weight loss and malnutrition. A Hunt-Lawrence pouch was constructed to provide gastric reservoir capacity and the child at 4-years follow-up has regained near normal weight for his age and is attending to school and other act...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2003-03-01 00:00:00
abstract:OBJECTIVE:To assess the safety and immunogenicity of a quadrivalent meningococcal (groups A,C,Y,W) polysaccharide diphtheria toxoid conjugate vaccine (MenACYW-DT) in India. DESIGN:Open-label, descriptive, non-randomized study. SETTING:Three medical college hospitals, one each in New Delhi, Bengaluru and Mumbai, India...
journal_title:Indian pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1007/s13312-014-0435-7
更新日期:2014-06-01 00:00:00
abstract::We report a case of toxic epidermal necrolysis who was successfully treated with intravenous immunoglobin and granulocyte colony-stimulating factor. He had poor prognostic factors such as extensive epidermal loss, neutropenia, acute respiratory distress syndrome and candida sepsis, but nonetheless made a complete reco...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2004-04-01 00:00:00
abstract::One hundred and four cases of osteoarticular tuberculosis were studied. There were 74 boys (71.2%) and 30 girls (28.8%). The mean age at the onset of symptoms was 7.3 years, ranging from 9 months to 18 years. Seventy four cases (71%) reported 3 months after onset of symptoms. The spine was the commonest site involved ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-09-01 00:00:00
abstract::The Retinopathy of Prematurity (ROP) epidemic is no more confined to metro cities and has spread to interior states including Eastern India. There is hardly any published data available on the subject, including the incidence and profile of babies with ROP, screening experience with binocular indirect ophthalmoscope a...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2016-11-07 00:00:00
abstract:OBJECTIVE:To compare the rate of optimal position of UVC between modified Shukla's formula and JSS formula. METHODS:Babies requiring umbilical vein catheterization were randomized to either Shukla or JSS formula group. Post-procedure X-ray was taken to check the tip position. Tip of the UVC just above the diaphragm (T...
journal_title:Indian pediatrics
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2019-03-15 00:00:00
abstract::Patent ductus arteriosus (PDA) is a major morbidity in preterm infants, especially in extremely premature infants less than 28 weeks. The clinical signs and symptoms of PDA in preterm infants are non specific and insensitive for making an early diagnosis of significant ductal shunting. Functional echocardiography is e...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s13312-011-0062-5
更新日期:2011-04-01 00:00:00
abstract::Bone mineral content (BMC) was determined at the distal radius in 70 children aged 2-14 years; Group I comprising 34 normal healthy children and Group II 36 malnourished children by the method of single photon absorptiometry. The mean value of BMC in Group I was 0.3 +/- 0.04 g/cm in 2-5 year, 0.52 +/- 0.08 g/cm in 6-1...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
abstract::Two hundred and fifty eight newborn babies were studied for the presence of retinal hemorrhages between 1-3 days of birth. The overall incidence of retinal hemorrhages was found to be 18.9%. It was observed that the incidence of retinal hemorrhages was higher in unassisted vaginal deliveries than in assisted births. A...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-02-01 00:00:00
abstract::Lead levels were measured by atomic absorption spectrophotometry in umbilical cord blood samples of 205 consecutively born neonates and venous blood in 62 of the mothers. The mean (+/- SD) cord blood lead level was 4.7 +/- 12.1 microg/dL. In the sub sample of 62 mother-baby pairs, the mean (+/- SD) cord blood lead lev...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2009-09-01 00:00:00
abstract::Many children report chronic abdominal pain that is severe and disruptive to normal lifestyle and schooling. Assessment and management depends on indentifying those with underlying organic disease, such as chronic infection, celiac disease or inflammatory bowel disease, but avoiding unnecessary invasive investigations...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2009-05-01 00:00:00
abstract::Madhya Pradesh has made remarkable progress in facility based management of severe acute malnutrition, and has developed a model that is being replicated in many states. India has uniquely high prevalence of both stunting and wasting, implying that both severe acute malnutrition and severe chronic malnutrition co-exis...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-014-0341-z
更新日期:2014-02-01 00:00:00
abstract::The phenotypic description of SHORT syndrome (OMIM- 269880) is expanding since its initial description in 1975. There have been 26 case reports till date but the genetic locus of this syndrome is elusive. Involvement of PITX2 gene initially envisaged is probably is not the only gene involved but has an important role ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-013-0099-8
更新日期:2013-04-01 00:00:00
abstract::We present the case of a 3-month-old girl who was admitted with complaints of loose stools and respiratory distress. She also had a history of rash and alopecia. Laboratory investigations revealed lymphopenia with reduced immunoglobulin G and immunoglobulin A. Lymphocyte subset analysis by flow cytometry revealed T-B+...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2018-08-15 00:00:00
abstract::Hepatitis is a known manifestation of congenital syphilis, however hepatitis developing during penicillin therapy is unknown. Ten patients of congenital syphilis were studied and serial liver enzymes were done before and after starting penicillin therapy. Eight of the ten patients developed hepatitis after initiating ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-02-01 00:00:00
abstract::Anthropometric data from our survey of 1,879 children in Madhya Pradesh revealed low sensitivity (17.5%) and positive predictive value (30.4%) of Mid-Upper Arm Circumference (MUAC) at the recommended cut-off of 115 mm for identifying Severe Acute Malnutrition (SAM). This led us to question the reliability of MUAC as a...
journal_title:Indian pediatrics
pub_type: 信件
doi:10.1007/s13312-013-0032-1
更新日期:2013-01-08 00:00:00
abstract::The study was conducted in an industrial and prosperous city of Punjab to evaluate the biophysical profile of blood pressure (BP) in apparently healthy school children. A total of 2560 children between the ages of 5-15 years were enrolled. Their age, religion, dietary and family history were recorded. Weight and heigh...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1995-07-01 00:00:00
abstract::Transfusion-related acute lung injury is a rare form of acute respiratory distress syndrome of possible immune etiology that develops immediately after a blood product transfusion. Clinicians need to be aware of this condition as prompt recognition and supportive management can prevent unwanted morbidity and mortality...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:To assess efficacy and safety of High flow nasal cannula therapy (HFNC) as primary mode of treatment for children with respiratory distress. METHODS:Consecutive patients (1 mo-16 years) with respiratory distress were assessed for respiratory clinical score, COMFORT score and saturation to FiO2 (SF) ratio. R...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2021-01-15 00:00:00
abstract::Association of rotavirus gastroenteritis with histo-blood group antigens in children younger than 5 years admitted with diarrhea (n=389) was studied. Distribution of blood groups in rotavirus positive (n=96) and rotavirus negative (n=51) diarrhea gastroenteritis cases did not show any susceptibility to any blood group...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2016-07-08 00:00:00
abstract::International Union of Immunological Societies working group recently updated the human inborn errors of immunity. This classification includes 65 new disorders that have been added since the last classification in 2018. This article highlights the important aspects of new classification for the benefit of general ped...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-06-15 00:00:00
abstract::Hepatic abscess in a neonate is a rare but serious disorder. Diagnosis of hepatic abscess requires a high index of suspicion in any septic neonate. CT scan and ultrasound of liver are the most sensitive diagnostic tests in detection of hepatic abscess. Portal vein thrombosis and portal cavernoma formation is hitherto ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVE:To evaluate simple clinical signs of illness in young infants (0 to 2 months) and to correlate with WHO IMCI algorithm (7 days-2 months). DESIGN:Prospective observational. Study conducted in the outpatient department and emergency room of a pediatric tertiary level hospital. METHODS:Four hundred and ninety ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2006-12-01 00:00:00
abstract::We prospectively studied the effect of oral paracetamol in closing hemodynamically significant Patent ductus arteriosus in preterm infants (gestational age <32 weeks) where Ibuprofen was contraindicated. 29 of 40 neonates (72.5%) showed successful response while 11 (29.5%) failed to show any response. No major complic...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:Gaucher disease in India has been reported only in a few case reports from India. The aim of the study was to assess the response to enzyme replacement therapy in Indian patients with Gaucher disease. DESIGN:Retrospective analysis of patients receiving CHO-derived recombinant macrophage-targetted glucocorebr...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-011-0128-4
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of high dose phenobarbital on lipid peroxidation and antioxidant enzymes in perinatal asphyxia. DESIGN:Open label, Randomized controlled trial. SETTING:Neonatal intensive care unit of a tertiary care teaching hospital. PARTICIPANTS:72 full term inborn neonates with severe birth asphy...
journal_title:Indian pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s13312-011-0106-x
更新日期:2011-08-01 00:00:00