Abstract：
OBJECTIVE:To study the etiological profile and patterns of clinical presentation of nephrocalcinosis. METHODS:In this observational study, patients 18 years or younger, referred to the pediatric nephrology clinic with nephrocalcinosis were evaluated for etiology. Symptoms/signs at presentation, estimated glomerular filtration rate (eGFR) at presentation and follow-up, and growth parameters were recorded. RESULTS:The etiology of nephrocalcinosis (n=54) included distal renal tubular acidosis (n=18; 33.3%), primary hyperoxaluria (n=9; 16.7%), Bartter syndrome (n=7; 13%), Dent disease (n=4; 7.4%), cystinosis, familial hypomagnesemia with hypercalciuria and idiopathic hypercalcemia of infancy (2 each). Idiopathic nephrocalcinosis was seen in 5 (9.3%) children. Clinical features included failure to thrive (53.7%), polyuria (44.4%), bony deformities (31.5%) and hypokalemic paralysis (11.1%). At a median (IQR) follow-up of 24 (8, 56) months, the mean (SD) eGFR had improved from 59 (25.5) to 77 (31.48) mL/min/1.73m2 (P<0.01). Consanguinity was present in 50% (27/54). Genetic analysis in 5 primary hyperoxaluria cases confirmed AGXT mutations in 4; and GRHPR mutation in 1 child. CONCLUSIONS:Distal RTA, primary hyperoxaluria and Bartter syndrome were the common etiologies of nephrocalcinosis in our patient population.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Ramya K,Krishnamurthy S,Sivamurukan Psubject
Has Abstractpub_date
2020-05-15 00:00:00pages
415-419issue
5eissn
0019-6061issn
0974-7559pii
S097475591600144journal_volume
57pub_type
杂志文章abstract：:Hepatitis is a known manifestation of congenital syphilis, however hepatitis developing during penicillin therapy is unknown. Ten patients of congenital syphilis were studied and serial liver enzymes were done before and after starting penicillin therapy. Eight of the ten patients developed hepatitis after initiating ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1991-02-01 00:00:00
abstract：OBJECTIVE:To assess the efficacy of nasal intermittent positive pressure ventilation with heliox in preterm infants with respiratory distress syndrome. METHODS:Premature infants with mild respiratory distress syndrome requiring non-invasive respiratory support were eligible. Infants were randomly assigned to heliox or...
journal_title：Indian pediatrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s13312-014-0524-7
更新日期：2014-11-01 00:00:00
abstract：NEED AND PURPOSE OF REVIEW:A number of newer anti-epileptic drugs have been developed in the last few years to improve the treatment outcomes in epilepsy. In this review, we discuss the use of newer anti-epileptic drugs in children. METHODS USED FOR LOCATING, SELECTING, EXTRACTING AND SYNTHESIZING DATA:MEDLINE search ...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s13312-013-0284-9
更新日期：2013-11-08 00:00:00
abstract：CONTEXT:Increased prevalence of obesity in childhood and adolescence, defined by the use of body mass index (BMI), has drawn attention towards direct measurement of body fat. OBJECTIVE:To develop age-and sex-specific reference distribution of body fat in apparently healthy North-Indian children in the age group of 7-1...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0237-3
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:To assess the safety and immunogenicity of a quadrivalent meningococcal (groups A,C,Y,W) polysaccharide diphtheria toxoid conjugate vaccine (MenACYW-DT) in India. DESIGN:Open-label, descriptive, non-randomized study. SETTING:Three medical college hospitals, one each in New Delhi, Bengaluru and Mumbai, India...
journal_title：Indian pediatrics
pub_type： 杂志文章,多中心研究
doi：10.1007/s13312-014-0435-7
更新日期：2014-06-01 00:00:00
abstract：OBJECTIVE:To determine the extent, epidemiological and clinical features of an epidemic of non-inflammatory encephalopathy in northern region of India. DESIGN:Surveillance of referred cases having unconsciousness after a short bout of fever during October and November 1997. Case control study in 7 most affected villag...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1999-11-01 00:00:00
abstract：BACKGROUND:Lysinuric protein intolerance is an inherited disorder of transport of cationic amino acids, causing amino aciduria. CASE CHARACTERISTICS:A 3-year-old boy with 12 month history of episodic change in behavior (decreased sleep, poor interaction), stunted growth and hyperammonemia. OUTCOME:Genetic analysis re...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-016-0920-2
更新日期：2016-08-08 00:00:00
abstract：:We performed a retrospective study of hospital records of children younger than 14 years with ocular trauma seen at our center in Sao Paulo, Brazil, between 2011 and 2012. From the total number of cases, 224 (89.2%) could be easily avoided. Accidents occurred with 5 children under 1 year of age; with one baby as young...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-12-26 00:00:00
abstract：OBJECTIVE:To determine the survival of children =18 y, treated with immunosuppressive therapy (IST) using equine antithymocyte globulin (e-ATG) and cyclosporine (CsA). DESIGN:Prospective data entry as per a specified format. SETTING:Tertiary care hospital. PATIENTS:From January 1998 to December 2009, 40 children wer...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-012-0086-5
更新日期：2012-05-01 00:00:00
abstract：:A 12-year-old male child reported with history of fever for last seven years. Hepatosplenomegaly, hepatic and bone marrow granulomas were the main features. Idiopathic Granulomatous Hepatitis (IGH), a rare syndrome amenable to immunosuppressive therapy was diagnosed. ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2004-06-01 00:00:00
abstract：:We evaluated 50 mothers of children with Down syndrome attending Genetic Clinic of the Institute of Child Health and Hospital for Children, Madras, with special reference to their knowledge, belief and attitudes in the care of these children. After evaluation, they were educated individually and in groups with demonst...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1991-09-01 00:00:00
abstract：OBJECTIVE:To compare the impact of postnatal lactational counseling on the weight gain and frequency of mixed feeding in full term neonates. DESIGN:Observational study. SETTING:Mother-infant pairs were observed in the maternity section of a multispecialty general hospital in Mumbai during two time periods. PARTICIPA...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-015-0678-y
更新日期：2015-07-01 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2009-10-01 00:00:00
abstract：:The prevalence of vitamin A deficiency was estimated in 366 rural children in the age group of 1 to 15 years. In a systematically selected subsample of 90 children, the dietary intake of vitamin A was assessed. The prevalence of vitamin A deficiency signs ranged from 24.1 to 34.8%. The adequacy of dietary intake of vi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1990-05-01 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1993-02-01 00:00:00
abstract：:Delayed diagnosis of undescended testes is a major problem. A retrospective review of 298 testes units was performed to assess the age at referral, age at operation, complications and final outcome. The mean age at referral was 57 months. Only 24% of cases were operated below 2 years. A similar pattern of delayed orch...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2008-06-01 00:00:00
abstract：:Transfusion-related acute lung injury is a rare form of acute respiratory distress syndrome of possible immune etiology that develops immediately after a blood product transfusion. Clinicians need to be aware of this condition as prompt recognition and supportive management can prevent unwanted morbidity and mortality...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2012-02-01 00:00:00
abstract：:The study was undertaken to compare the antibody response of 6-12 weeks old infants after three doses of standard trivalent oral polio vaccine (TOPV) (Groups A; (n = 42) with three doses of double the amount of TOPV (Group B; n = 35). Seroconversions in Group A were 64.2, 80.9% and 57.1% for Types I, II and III poliov...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：BACKGROUND:Fetal growth restriction and abnormal Doppler flow studies are commonly associated. Neonatal outcomes are not well known particularly in developing countries, where the burden of the disease is the highest. OBJECTIVE:To determine outcomes of preterm infants with history of absent/reversed end-diastolic umbi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0235-5
更新日期：2013-09-01 00:00:00
abstract：:We studied the level of food insecurity among households with HIV-infected children and its relationship with childhood nutritional indicators. Among the 147 children assessed, food insecurity was present in 59% of households. Majority of children with stunting belonged to-food insecure families. Stunting and Underwei...
journal_title：Indian pediatrics
pub_type： 信件
doi：
更新日期：2015-03-08 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0034-z
更新日期：2013-01-08 00:00:00
abstract：:One hundred ninety one children below 5 years of age suffering from poliomyelitis were analyzed to find out the immunization status and its correlation with the incidence of poliomyelitis. Effects of age, sex, immunization status and seasonal variation on the morbidity and mortality status were studied. The maximum nu...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1991-06-01 00:00:00
abstract：OBJECTIVES:To generate evidence on the current situation of hospital care (emergency, inpatient and outpatient), for managing children presenting with diarrhea and pneumonia at 13 district hospitals in India. DESIGN:Facility-Based assessment of district hospitals. SETTINGS:13 district hospitals in four states of Biha...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2021-01-02 00:00:00
abstract：OBJECTIVE:To describe the clinical profile of children with bacteriologically confirmed tuberculosis. STUDY DESIGN:A multicentric study was conducted in three hospitals in Chennai city between July 1995 and December 1997. Children aged 6 months to 12 years with signs and symptoms suggestive of tuberculosis were invest...
journal_title：Indian pediatrics
pub_type： 杂志文章,多中心研究
doi：
更新日期：2008-09-01 00:00:00
abstract：:The year 2013 marks 50 years of both newborn screening and the Indian Academy of Pediatrics. India has seen a lot of change in terms of motivation, evolution and implementation of newborn screening as pilot projects for few disorders. Facilities for implementing screening using tandem mass spectrometry or what is term...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0187-9
更新日期：2013-07-01 00:00:00
abstract：:Psychosocial assessment was carried out in 35 children with acute lymphatic leukemic, an equal number with non-leukemic chronic illness and their parents. Psychological dysfunction existed more frequently in parents of leukemic children. Depression as an initial reaction on being conveyed the diagnosis, was seen in 85...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1992-08-01 00:00:00
abstract：:Cord problems at birth were prospectively studied in 12,000 singleton deliveries, of which 258 (2.15%) babies had cord abnormalities. Nearly 32% of these cases had fetal distress and 20.5% had 1 minute Apgar score less than 6. Of the various cord problems nuchal cord was noted in 79.1%, cord prolapse in 12.4% and true...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1992-03-01 00:00:00
abstract：:In this cohort study, neurodevelopmental outcome of 20 of 24 surviving very low birth weight infants with sepsis followed up between 2008 and 2009 was compared with 20 control (uninfected infants). We found that plasma interleukin 6 and C reactive protein values were negatively correlated with mental developmental ind...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0091-3
更新日期：2013-03-01 00:00:00
