Abstract：
OBJECTIVE:To study the association between common AIDS restriction genes and slow disease progression among perinatally-infected children in India. METHODS:ART-naïve children were identified and selected host factors including CCR5-∆32, SDF1-3'A, CCR5-59029G, HLA-B*27, B*57 were studied using allele-specific PCR-RFLP and SSPGo HLA typing kits. RESULTS:Among 165 children, 10 (6%) long-term non-progressors and 8 (5%) slow progressors were identified. For comparison, 12 children with normal progression of HIV were included. The frequencies of CCR5-∆32 deletion, SDF1-3'A and CCR5-59029G did not differ significantly. HLA-B*27 and B*57 were observed only in long-term non-progressors or slow progressors, who also harbored either SDF1-3'A and/or CCR5-59029G. CONCLUSIONS:There is an association between host genetic factors and slow disease progression in this population.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Chaudhuri RP,Neogi U,Rao SD,Shet Adoi
10.1007/s13312-014-0505-xsubject
Has Abstractpub_date
2014-10-01 00:00:00pages
801-3issue
10eissn
0019-6061issn
0974-7559journal_volume
51pub_type
杂志文章abstract：:International Union of Immunological Societies working group recently updated the human inborn errors of immunity. This classification includes 65 new disorders that have been added since the last classification in 2018. This article highlights the important aspects of new classification for the benefit of general ped...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-06-15 00:00:00
abstract：OBJECTIVE:To observe the safety and efficacy of Colistimethate sodium in children infected with gram-negative bacteria, susceptible only to colistimethate sodium. METHODS:This prospective observational study done over 2 years observed children who received colistin for >48 h, for renal failure as defined by p-RIFLE cr...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-015-0586-1
更新日期：2015-02-01 00:00:00
abstract：:Jaundice as a presenting feature of pediatric acute myeloid leukemia is rare. We report two cases of AML who presented with obstructive jaundice, one with a malignant stricture at the common bile duct and other with a granulocytic sarcoma obstructing the bile duct. The prognosis is poor in these patients. ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2012-05-01 00:00:00
abstract：OBJECTIVE:To study the relationship of CSF IL-1 beta and TNF-alpha with free radicals in acute bacterial meningitis (ABM) and to evaluate the clinical outcome in relation to the levels of these cytokines and free radicals in CSF. DESIGN:Prospective with controls. SETTING:Referral unit of a teaching hospital. METHODS...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：:The phenotypic description of SHORT syndrome (OMIM- 269880) is expanding since its initial description in 1975. There have been 26 case reports till date but the genetic locus of this syndrome is elusive. Involvement of PITX2 gene initially envisaged is probably is not the only gene involved but has an important role ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0099-8
更新日期：2013-04-01 00:00:00
abstract：:We report a case of primary hyperparathyroidism associated with prolonged hungry syndrome (HBS) after parathyroid adenomectomy in a 10-year-old girl. Bone mineral density (BMD) revealed severe loss of cancellous BMD. Overt bone disease, high alkaline phosphatase, decreased cancellous BMD and a large adenoma can be use...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2009-02-01 00:00:00
abstract：:Trichotillomania, though uncommon, is one of the causes of unexplained hair loss, especially in children. Three girls in the age group of 4-6 years were observed in our pediatric dermatology clinic to have trichotillomania. In one child, there was co-existent alopecia areata. All were referred to the child guidance cl...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:We conducted a case control study to compare the quality of life (QOL) in 40 cases of HIV infected children and 40 demographically matched controls with other chronic ailments at a referral hospital in Northern India. Quality of life among HIV infected children was significantly better in psychosocial (P=0.008), emoti...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0300-0
更新日期：2013-12-01 00:00:00
abstract：:The Retinopathy of Prematurity (ROP) epidemic is no more confined to metro cities and has spread to interior states including Eastern India. There is hardly any published data available on the subject, including the incidence and profile of babies with ROP, screening experience with binocular indirect ophthalmoscope a...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2016-11-07 00:00:00
abstract：NEED AND PURPOSE OF REVIEW:A number of newer anti-epileptic drugs have been developed in the last few years to improve the treatment outcomes in epilepsy. In this review, we discuss the use of newer anti-epileptic drugs in children. METHODS USED FOR LOCATING, SELECTING, EXTRACTING AND SYNTHESIZING DATA:MEDLINE search ...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s13312-013-0284-9
更新日期：2013-11-08 00:00:00
abstract：OBJECTIVE:To assess efficacy and safety of High flow nasal cannula therapy (HFNC) as primary mode of treatment for children with respiratory distress. METHODS:Consecutive patients (1 mo-16 years) with respiratory distress were assessed for respiratory clinical score, COMFORT score and saturation to FiO2 (SF) ratio. R...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2021-01-15 00:00:00
abstract：OBJECTIVES:To evaluate whether zinc supplements prevent mortality and morbidity in breastfed low birth weight infants. METHODS:All randomized or qausi-randomized trials with individual or cluster allocation and using concurrent controls were included. Study population included LBW infants irrespective of gestational s...
journal_title：Indian pediatrics
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s13312-011-0043-8
更新日期：2011-02-01 00:00:00
abstract：: ...
journal_title：Indian pediatrics
pub_type： 信件
doi：
更新日期：2019-02-15 00:00:00
abstract：OBJECTIVE:To study the incidence and risk factors predisposing to retinopathy of prematurity (ROP) and to assess the outcome after laser photocoagulation. DESIGN:Prospective cohort observational study. SETTING:Infants admitted to a neonatal intensive care unit of a referral hospital between 2000-2006 and followed up ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2009-03-01 00:00:00
abstract：Background:We describe the demographic, clinical and labo-ratory findings along with the treatment and outcomes among children meeting the case definition of Pediatric Inflammatory Multisystem Syndrome - Temporally associated with SARS-CoV-2 (PIMS-TS). METHODS:We analyzed the clinical and laboratory findings of childr...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-11-15 00:00:00
abstract：:The study was conducted in an industrial and prosperous city of Punjab to evaluate the biophysical profile of blood pressure (BP) in apparently healthy school children. A total of 2560 children between the ages of 5-15 years were enrolled. Their age, religion, dietary and family history were recorded. Weight and heigh...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1995-07-01 00:00:00
abstract：BACKGROUND:Inflammatory pseudo tumor, a rare non-neoplastic lesion, commonly presents as slow growing solid lesion in the lung, but many extra-pulmonary locations have been described. CASE CHARACTERISTICS:A 4-year-old girl who presented with respiratory distress due to massive pleural effusion. Computed tomography rev...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2018-04-15 00:00:00
abstract：OBJECTIVE:To evaluate serum leptin levels in obese Indian children and its correlation to anthropometric and biochemical parameters. DESIGN:Cohort study. SETTING:Referral tertiary hospital. METHODOLOGY:Leptin levels were measured in 36 children (26 boys, age 1.5 to 15 years) and 37 adults (21 men, age 25 to 69 years...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2007-04-01 00:00:00
abstract：:We present the case of a 3-month-old girl who was admitted with complaints of loose stools and respiratory distress. She also had a history of rash and alopecia. Laboratory investigations revealed lymphopenia with reduced immunoglobulin G and immunoglobulin A. Lymphocyte subset analysis by flow cytometry revealed T-B+...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2018-08-15 00:00:00
abstract：BACKGROUND:Glycogen storage disease type VI (GSD-VI) presents with failure to thrive and also fibrosis in some cases, without cirrhosis. CASE CHARACTERISTICS:2½-year-old girl presented with short stature, transaminase elevation and significant fibrosis, suggesting GSD-III. OBSERVATION:A pathogenic mutation in PYGL ge...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-017-1174-3
更新日期：2017-09-15 00:00:00
abstract：:A 5 year old boy and a 10 year old girl presented with acute onset of psychotic disorder, which occurred one week after an upper respiratory infection. MRI images of brain were consistent with the diagnosis of acute disseminated encephalomyelitis (ADEM) in both cases. ADEM is one of the differential diagnoses to be co...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2008-12-01 00:00:00
abstract：:Cord problems at birth were prospectively studied in 12,000 singleton deliveries, of which 258 (2.15%) babies had cord abnormalities. Nearly 32% of these cases had fetal distress and 20.5% had 1 minute Apgar score less than 6. Of the various cord problems nuchal cord was noted in 79.1%, cord prolapse in 12.4% and true...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1992-03-01 00:00:00
abstract：:We report on 16 children with ingestion of magnetic foreign bodies, who were identified by a medical record review of our hospital data for the time period between January, 2017 and May, 2018. Digestive tract wall was sandwiched in 13 (75%) children and 11 (74%) had gaptic intestinal perforation. ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-06-24 00:00:00
abstract：CONTEXT:Increased prevalence of obesity in childhood and adolescence, defined by the use of body mass index (BMI), has drawn attention towards direct measurement of body fat. OBJECTIVE:To develop age-and sex-specific reference distribution of body fat in apparently healthy North-Indian children in the age group of 7-1...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0237-3
更新日期：2013-09-01 00:00:00
abstract：:Avian flu is affecting the poultry animals world over since first outbreak in 1997 in Hong Kong and has resulted in 92 human deaths and culling of more than 150 million poultry animals in Asia and Europe. The loss to the economy has also been enormous. 13 new countries, including India, reported occurrence of the dise...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：2006-04-01 00:00:00
abstract：OBJECTIVE:To assess the utility of computer-aided facial analysis in identifying dysmorphic syndromes in Indian children. METHODS:Fifty-one patients with a definite molecular or cytogenetic diagnosis and recognizable facial dysmorphism were enrolled in the study and their facial photographs were uploaded in the Face2G...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2019-12-15 00:00:00
abstract：OBJECTIVE:To investigate association between dietary habits and asthma severity in children. DESIGN:Cross-sectional study. SETTING:Two teaching hospitals in Brazil. PARTICIPANTS:Cases (n=268) were children (3-12yr) with persistent asthma and age-matched controls (n=126) were those with intermittent asthma. MAIN OUT...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-015-0561-x
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the profile of children with central diabetes insipidus (DI) and identify factors indicating organic etiology. DESIGN:Retrospective chart review. SETTING:Tertiary referral hospital. SUBJECTS:Fifty-nine children with central DI (40 boys, 19 girls). METHODS:Features of organic and idiopathic cen...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2008-06-01 00:00:00
abstract：:We report on long-term follow-up [mean (SD) duration, 44.7 (4.3) mo] of 48 out of 132 children with recurrent abdominal pain, who were a part of an earlier study at our hospital. 31 (64.5%) children still experienced pain; 26 (54.1%) reported their pain to be better than before, 4 children reported it to be same as be...
journal_title：Indian pediatrics
pub_type： 信件
doi：
更新日期：2020-05-15 00:00:00
abstract：BACKGROUND:E-type prostaglandins (PGE1) can effectively maintain the patency of the ductus arteriosus in neonates. Its use, therefore and be life saving in infants born with ductus dependent congenital heart disease. Although PGE1 is available for over two decade in western world, it has been introduced in India only s...
journal_title：Indian pediatrics
pub_type： 临床试验,杂志文章
doi：
更新日期：1998-11-01 00:00:00
