Abstract：
OBJECTIVE:To evaluate serum leptin levels in obese Indian children and its correlation to anthropometric and biochemical parameters. DESIGN:Cohort study. SETTING:Referral tertiary hospital. METHODOLOGY:Leptin levels were measured in 36 children (26 boys, age 1.5 to 15 years) and 37 adults (21 men, age 25 to 69 years) with obesity and 29 normal weight controls (15 children and 14 adults). RESULTS:Leptin levels were higher than controls in obese children (19.4 +/- 6.4 ng/mL against 5.4 +/- 1.7 ng/mL, p = 0.0001) and obese adults (18.9 +/- 6.4 ng/mL against 7.8 +/- 5.6 ng/mL, p = 0.0001). Leptin levels were higher than males in obese girls (23.5 +/- 1.7 ng/mL against 18.0 +/-7.6 ng/mL, p = 0.040) and women (21.3 +/- 4.4 ng/mL against 15.8 +/- 7.4 ng/mL). Leptin levels correlated with body mass index, waist circumference and waist to-hip ratio. A positive correlation was observed between serum leptin and cholesterol, triglycerides and LDL-cholesterol. No correlation was seen with fasting blood glucose and HDL-cholesterol. CONCLUSIONS:Leptin levels correlate significantly with anthropometric and laboratory parameters in obese children. There is a need for further studies on the role of leptin in childhood obesity and metabolic syndrome.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Dubey S,Kabra M,Bajpai A,Pandey RM,Hasan M,Gautam RK,Menon PSsubject
Has Abstractpub_date
2007-04-01 00:00:00pages
257-62issue
4eissn
0019-6061issn
0974-7559journal_volume
44pub_type
杂志文章abstract：:The distribution of supplementary nutrition (SN) to beneficiaries is an issue of debate in the Integrated Child Development Services (ICDS) program, discussed in almost all fora in which the scheme is on the agenda. ICDS program managers rightly decided in 1975 to make SN a program component, and it should remain so....
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：1998-03-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of clofibrate for unconjugated hyperbilirubinemia in neonates. METHODS:A systematic review with meta-analysis of randomized controlled trials or quasi-randomized controlled trials was conducted to evaluate the clofibrate treatment in neonates with unconjugated hyperbilirubinemia. We fo...
journal_title：Indian pediatrics
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s13312-012-0012-x
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:Blue rubber bleb nevus syndrome is a rare clinical entity. CASE CHARACTERISTICS:A 13-year-old Indian boy presented with characteristic cutaneous lesions, gastrointestinal malformations, skeletal involvement and pulmonary stenosis. OBSERVATIONS:Diagnosis was confirmed on skin biopsy, radiographic evaluation...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-016-0884-2
更新日期：2016-06-08 00:00:00
abstract：:A case of idiopathic hypereosinophilic syndrome who had an unusual presentation in the form of pericardial effusion is being presented here. The child initially responded to corticosteroids but could not maintain normal eosinophil counts on tapering of steroids. Therefore he was put on hydroxyurea and low dose of ster...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:Delayed diagnosis of undescended testes is a major problem. A retrospective review of 298 testes units was performed to assess the age at referral, age at operation, complications and final outcome. The mean age at referral was 57 months. Only 24% of cases were operated below 2 years. A similar pattern of delayed orch...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2008-06-01 00:00:00
abstract：:The study was undertaken to compare the antibody response of 6-12 weeks old infants after three doses of standard trivalent oral polio vaccine (TOPV) (Groups A; (n = 42) with three doses of double the amount of TOPV (Group B; n = 35). Seroconversions in Group A were 64.2, 80.9% and 57.1% for Types I, II and III poliov...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：OBJECTIVE:To determine the extent, epidemiological and clinical features of an epidemic of non-inflammatory encephalopathy in northern region of India. DESIGN:Surveillance of referred cases having unconsciousness after a short bout of fever during October and November 1997. Case control study in 7 most affected villag...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1999-11-01 00:00:00
abstract：:Children with cow milk allergy are suspected to develop calcium metabolism disturbances. We observed increased markers of bone turnover in these children. Children with cow milk allergy are more prone to develop the disturbances of the bone mineralization even in the first year of life. ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0194-x
更新日期：2013-07-01 00:00:00
abstract：:Shwachman-Diamond Syndrome (SDS) is a rare inherited disorder characterized by pancreatic insufficiency, bone marrow dysfunction and skeletal abnormalities. It is the most common cause of pancreatic insufficiency in children after cystic fibrosis. We report a child with classical SDS who presented to us predominantly ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-012-0138-x
更新日期：2012-09-01 00:00:00
abstract：: ...
journal_title：Indian pediatrics
pub_type： 评论,杂志文章
doi：
更新日期：2019-09-15 00:00:00
abstract：:International Union of Immunological Societies working group recently updated the human inborn errors of immunity. This classification includes 65 new disorders that have been added since the last classification in 2018. This article highlights the important aspects of new classification for the benefit of general ped...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-06-15 00:00:00
abstract：:One hundred nine patients presenting with ambiguous genitalia over the past 10 years (year 1995 to 2004) to Pediatric Endocrine Service of our hospital were reviewed. On the basis of clinical and investigative evaluation like hormonal and biochemical estimations, imaging studies, karyotype and invasive techniques like...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2006-11-01 00:00:00
abstract：:Ensuring quality in healthcare today has become extremely essential to ensure adequate utilization of healthcare services and improved outcomes. In addition to essential infrastructure in terms of safe and adequate space, knowledgeable and skilled health workers, and essential equipment and supply, the healthcare team...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：2018-09-15 00:00:00
abstract：OBJECTIVE:To analyze variation in rotavirus-positivity using simple alternative statistical measures. METHODS:Hospital-based rotavirus surveillance among children admitted with acute gastroenteritis between 2005 and 2009. Prevalence, adjusted proportions and symmetrized index were calculated. RESULTS:Rotavirus preval...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-016-0898-9
更新日期：2016-07-08 00:00:00
abstract：:The morbidity pattern and nutritional profile was evaluated of school children who resided around Mosaboni Copper Mines and in surrounding villages of Ghatsila subdivision in Singhbhum district of Bihar State, India. A total of 1424 school children (816 boys and 608 girls) between 5-17 years old were studied. Children...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1989-06-01 00:00:00
abstract：:Seventy five mothers with lactation failure were studied, whose less than 4-month-old babies were admitted to the hospital. Partial lactational failure (94.7%) was noted more often than complete lactational failure (5.3%). Initiation of breastfeeding was delayed for 2 to 5 days usually for traditional reasons (77.3%) ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1992-12-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of canakinumab on growth parameters of patients with autoinflammatory diseases. METHODS:This retrospective study included Colchicine resistant familial Mediterranean fever (FMF), Mevalonate kinase deficiency (MKD), Tumor necrosis factor receptor-associated periodic fever syndrome (TRAP...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-07-15 00:00:00
abstract：BACKGROUND:Clinical presentations of intestinal lymphangiectasia include pitting edema, chylous ascites, pleural effusion, diarrhea, malabsorption and intestinal obstruction. CASE CHARACTERISTICS:An 8-year-old male child presented to the emergency department with clinical features of peritonitis, raising suspicion of ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2018-10-15 00:00:00
abstract：:The skinfold thickness (SFT) was measured in 750 Punjabi newborns at triceps and subscapular sites using a Harpenden's Caliper. It was correlated with various maternal and neonatal factors. SFT increased with increasing gestation but showed a decline after 40 weeks. There was a positive correlation of SFT with birth w...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1991-11-01 00:00:00
abstract：:Twenty-six neonates were diagnosed to have acinetobacter sepsis during 1986-90, representing 6.5% of all cases of bacteriologically proven sepsis. Of these 19 neonates were low birth weight (LBW) 12 were small for gestational age (SGA). Nineteen neonates had early-onset sepsis. The male to female ratio was 9:17. The h...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1993-12-01 00:00:00
abstract：OBJECTIVE:To assess the utility of computer-aided facial analysis in identifying dysmorphic syndromes in Indian children. METHODS:Fifty-one patients with a definite molecular or cytogenetic diagnosis and recognizable facial dysmorphism were enrolled in the study and their facial photographs were uploaded in the Face2G...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2019-12-15 00:00:00
abstract：OBJECTIVE:To study the etiological profile and patterns of clinical presentation of nephrocalcinosis. METHODS:In this observational study, patients 18 years or younger, referred to the pediatric nephrology clinic with nephrocalcinosis were evaluated for etiology. Symptoms/signs at presentation, estimated glomerular fi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-05-15 00:00:00
abstract：:We report on the etiology and the short term outcome (3 month) of children with acute renal failure (ARF) at a tertiary care centre in north India. Acute tubular necrosis was the commonest cause of ARF (33%) especially in children <5 years of age; while in children >10 years, glomerulonephritis was the commonest cause...
journal_title：Indian pediatrics
pub_type： 信件
doi：
更新日期：2011-06-01 00:00:00
abstract：:Primary immunodeficiency disorders (PIDs) are a heterogeneous group of inherited disorders that affect different components of the immune system. There are more than 150 different disorders which have been described till date. Despite major advances in the molecular characterization of PIDs over the last 20 years, man...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s13312-013-0171-4
更新日期：2013-06-08 00:00:00
abstract：BACKGROUND:Multiple pituitary hormone deficiency and Turner syndrome have overlapping features in peripubertal girls and is a diagnostic challenge. CASE CHARACTERISTICS:16-year-old girl having Turner phenotype undergoing evaluation for severe short stature and pubertal arrest. OBSERVATION:45,X karyotype, and multiple...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-015-0721-z
更新日期：2015-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the current spectrum of hepatobiliary disorders in children in Northern India. SETTING:Tertiary level referral hospital. METHODS:All children with hepatobiliary disorders presenting between January 1992 through July 1995 were evaluated by clinical assessment, liver function tests, viral and auto...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1997-10-01 00:00:00
abstract：BACKGROUND:Outcome of pseudomonas enteric fever is unpredictable as multiple systemic lethal complications occur abruptly. CASE CHARACTERISTICS:A 9-month-old girl with multiple ileal perforations, leukocoria, ecthyma gangrenosum, hemiplegia and a perforated ulcer in the soft palate. Blood culture suggested Pseudomonas...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-015-0741-8
更新日期：2015-10-01 00:00:00
abstract：:Immune thrombocytopenic purpura (ITP) has witnessed many changes and updates over the past decade. The definitions of disease subtypes, course and response to treatment have all been standardized recently. Consequent to the lack of an international consensus management guideline, wide variations exist in treatment pra...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s13312-012-0195-1
更新日期：2012-10-01 00:00:00
abstract：:This study was conducted in 2006 to assess the current iodine nutriure of the population in Haryana by assessing the urinary iodine excretion levels amongst the school age children between 6-12 years. Altogether 3,019 urine samples were collected from all the 19 districts in Haryana. The urinary iodine was analyzed by...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:In an earlier study usefulness and validity of calf circumference in the identification of low birth weight (LBW) infants was reported. To evolve a simple indicator in identifying LBW in community, comparative evaluation of three simple measurements, i.e., circumferences of calf (CC), thigh (TC) and arm (AC) was done ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
