Abstract：
:Immune thrombocytopenic purpura (ITP) has witnessed many changes and updates over the past decade. The definitions of disease subtypes, course and response to treatment have all been standardized recently. Consequent to the lack of an international consensus management guideline, wide variations exist in treatment practice. This is now being addressed to an extent by the much awaited ITP International Working Group 2010 recommendations. The pathophysiologic mechanisms have been unfolded at cellular, molecular and humoral levels. As a result, many recent advances have taken place in the management of this disorder. This review revisits the history of evolution of ITP, summarizes the current recommendations for management and lists the recent advances and future prospects in this field.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Anoop Pdoi
10.1007/s13312-012-0195-1subject
Has Abstractpub_date
2012-10-01 00:00:00pages
811-8issue
10eissn
0019-6061issn
0974-7559journal_volume
49pub_type
杂志文章,评审abstract：OBJECTIVE:To study the relationship of CSF IL-1 beta and TNF-alpha with free radicals in acute bacterial meningitis (ABM) and to evaluate the clinical outcome in relation to the levels of these cytokines and free radicals in CSF. DESIGN:Prospective with controls. SETTING:Referral unit of a teaching hospital. METHODS...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：OBJECTIVE:To evaluate endothelial function and arterial mechanics in apparently healthy overweight adolescents. DESIGN:Analytical observational study. SETTING:Tertiary hospital. METHODS:40 asymptomatic, normotensive and non-smoking adolescents (11 to 18 years old) were evaluated. Of these 20 were overweight or obese...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2004-11-01 00:00:00
abstract：BACKGROUND:Antiphospholipid syndrome is a multisystem auto-immune disorder characterized by arterial or venous thrombosis in children. CASE CHARACTERISTICS:11-year-old child with pneumococcal meningitis also had cerebral sinus vein thrombosis and pulmonary artery segmental thrombosis. OBSERVATION:Pro-thrombotic evalu...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2018-05-15 00:00:00
abstract：:Meropenem is a new carbapenem antibacterial agent with wide spectrum of activity against gram-negative, gram-positive and anaerobic organisms. It is stable against most beta-lactamases produced by gram-negative bacteria and has greatest utility in treating severe infections in hospitalized children. It has good CSF pe...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：2005-05-01 00:00:00
abstract：OBJECTIVE:To find out the degree of current undernutrition in rural reproductive age women. SETTING:49 villages of two adjoining rural blocks of Varanasi. METHODS:6130 non-pregnant and non-lactating rural women in the age group 18-45 year were studied for sociodemographic characteristics and anthropometry, i.e., weig...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：OBJECTIVE:To assess the glycometabolic function in chronically transfused patients of beta- thalassemia major in terms of glucose tolerance, insulin secretion, insulin resistance index, and beta cell function index and to determine their relationship with clinical and biochemical profile. METHODS:30 homozygous thalass...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2006-05-01 00:00:00
abstract：:The study was conducted in an industrial and prosperous city of Punjab to evaluate the biophysical profile of blood pressure (BP) in apparently healthy school children. A total of 2560 children between the ages of 5-15 years were enrolled. Their age, religion, dietary and family history were recorded. Weight and heigh...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1995-07-01 00:00:00
abstract：OBJECTIVE:To describe the utility of flexible fiberoptic bronchoscopy for the diagnosis and management in the neonatal ICU. METHODS:A retrospective, medical chart review was conducted in neonates who underwent flexible fiberoptic bronchoscopy over a period of 7 years. Besides demographic data and diagnostic findings, ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2019-07-15 00:00:00
abstract：:Jaundice as a presenting feature of pediatric acute myeloid leukemia is rare. We report two cases of AML who presented with obstructive jaundice, one with a malignant stricture at the common bile duct and other with a granulocytic sarcoma obstructing the bile duct. The prognosis is poor in these patients. ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2012-05-01 00:00:00
abstract：OBJECTIVE:To estimate the prevalence of rotavirus diarrhea among hospitalized children less than 5 years of age in Kerala State and to determine the circulating strains of rotavirus in Kerala. DESIGN:Multicenter, cross-sectional study. SETTING:Eight representative hospitals in Kunnathunadu Thaluk, Ernakulam district,...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-014-0329-8
更新日期：2014-01-01 00:00:00
abstract：:Thrombocytosis is a frequent finding in hemograms obtained from hospitalized and ambulatory children due to the widespread use of automated blood cell counters. Pediatricians are commonly puzzled in cases of thrombocytosis to determine the underlying cause and the need for therapy. The purpose of this review is to ass...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：2008-08-01 00:00:00
abstract：:To document the normal values of pulmonary function tests in children and changes occurring in their values with various respiratory disorders, a study was carried over a period of one year in 95 healthy controls (39 females and 56 males) of 8-13 years of age and 51 cases with respiratory disorders (bronchial asthma-3...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1995-06-01 00:00:00
abstract：:Familial chylomicronemia syndrome is a group of rare genetic disorders characterized by deficient activity of an enzyme lipoprotein lipase or apo-protein C-II deficiency. In this paper we present an infant with massive hyperchylomicronemia and severe pancreatitis. Exchange transfusion for controlling hypertriglyceride...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2007-04-01 00:00:00
abstract：:We performed a retrospective study of hospital records of children younger than 14 years with ocular trauma seen at our center in Sao Paulo, Brazil, between 2011 and 2012. From the total number of cases, 224 (89.2%) could be easily avoided. Accidents occurred with 5 children under 1 year of age; with one baby as young...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-12-26 00:00:00
abstract：BACKGROUND:Neuroschistosomiasis is an uncommonly reported disease. CASE CHARACTERISTICS:An adolescent Indian boy residing in Kenya presented with headache, visual symptoms and seizures, with MRI showing space-occupying lesions in the occipital lobe and cerebellum. OBSERVATION:Brain biopsy was diagnostic of neuro-schi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2018-11-15 00:00:00
abstract：:A quadrivalent MMRV (measles-mumps-rubella-varicella) combination vaccine has recently been launched in India. This vaccine is highly immunogenic, with seroconversion rates against all antigens reaching 96.6-100% at 42 to 56 days after the second vaccine dose in unvaccinated children or in those previously vaccinated ...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s13312-017-1209-9
更新日期：2017-12-15 00:00:00
abstract：:No clear operational definition of 'Community Participation' has emerged over the last decade of experimentation. One reason is the markedly contrasting perspectives that exist at different levels such as Aid Agencies, Ministry of Health, Government Health Programmes and Non-Government Organizations (NGOs). A more pra...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1989-11-01 00:00:00
abstract：OBJECTIVE:To study the effect of oil massage on growth and neurobehavior in preterm babies less than 1500 g. DESIGN:Randomized Controlled Trial. SETTING:Tertiary level neonatal unit of a teaching hospital. SUBJECTS:Neonates with birth weight <1500 grams, gestation >37 weeks, receiving enteral feeds of at least 100 m...
journal_title：Indian pediatrics
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2005-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the frequency of non-autoimmune subclinical and overt hypothyroidism in children with idiopathic steroid-resistant nephrotic syndrome (SRNS). METHODS:This cross-sectional study recruited 30 children (age 1-18 y) with idiopathic SRNS; and 30 healthy controls. Serum T3, T4 and TSH were performed in...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-017-1183-2
更新日期：2017-11-15 00:00:00
abstract：:Marfan syndrome rarely presents with peripheral artery and pulmonary artery aneurysms. We are presenting a case of a fifteen-year-old boy who presented to us with progressive lower abdominal pulsatile swelling with bruit in the right inguinal region for one month. He had typical marfanoid habitus, though there was no ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2013-05-08 00:00:00
abstract：:Madhya Pradesh has made remarkable progress in facility based management of severe acute malnutrition, and has developed a model that is being replicated in many states. India has uniquely high prevalence of both stunting and wasting, implying that both severe acute malnutrition and severe chronic malnutrition co-exis...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-014-0341-z
更新日期：2014-02-01 00:00:00
abstract：:Two hundred and forty four girls with different hemoglobin levels were selected, of which forty-one were non-anemic. The rest were graded as mildly, moderately or severely anemic and supplemented with 60 mg of iron daily or twice weekly for twelve weeks. There was no significant difference in the increase in hemoglobi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2003-12-01 00:00:00
abstract：:We report a case of toxic epidermal necrolysis who was successfully treated with intravenous immunoglobin and granulocyte colony-stimulating factor. He had poor prognostic factors such as extensive epidermal loss, neutropenia, acute respiratory distress syndrome and candida sepsis, but nonetheless made a complete reco...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2004-04-01 00:00:00
abstract：:The study aimed to explore the perception and knowledge-gain of undergraduate medical students during the Medical Council of India-mandated one month foundation course in August, 2019. A total of 129 consenting students who underwent the foundation course were enrolled and their feedback collected using an email-based...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-03-15 00:00:00
abstract：:This paper explores the relationships between maternal weight, height and poor pregnancy outcome using a data set from a case-control study of low birth weight (LBW) and perinatal mortality in Ahmedabad, India. Maternal height and weights were compared between mothers of 611 perinatal deaths, 644 preterm-LBW, and 1465...
journal_title：Indian pediatrics
pub_type： 杂志文章,多中心研究
doi：
更新日期：1994-10-01 00:00:00
abstract：:Eighteen cyanotic congenital heart disease (CCHD) and 17 acyanotic congenital heart disease (ACHD) patients in the age range of 2 months to 10 years along with their age and nutrition matched controls were studied for bactericidal, chemotactic and phagocytic functions. Bactericidal and phagocytic functions were signif...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1993-07-01 00:00:00
abstract：:Spinal muscular atrophy (SMA) represents the second most common fatal autosomal recessive disorder after cystic fibrosis. Due to the high carrier frequency, the burden of this genetic disorder is very heavy in developing countries like India. The aim was to study the clinical and molecular characteristics of patients ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0168-z
更新日期：2013-06-08 00:00:00
abstract：:Decline in malnutrition levels has been dismal since the 1990s. We ascertained decadal trend in childhood nutritional status between 1997 and 2007 in Chandigarh, India and assessed impact of Integrated Child Development Services (ICDS) on childhood undernutrition. A total of 803 under-five children, 547 children betwe...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-011-0058-1
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:To describe the clinical characteristics and outcome of Indian children infected with 2009 H1N1 influenza virus. STUDY DESIGN:Retrospective chart review. SETTING:Outpatient department and hospitalized patients in a tertiary care hospital. METHODS:Clinical details of 85 children (positive for the 2009 H1N1 ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-011-0085-y
更新日期：2011-05-01 00:00:00
abstract：:There is a paucity of data on the incidence of sporadic viral hepatitis in Indian children. Clinical, biochemical and etiological profile of 54 patients with acute viral hepatitis was evaluated. Of these, 32 (59.25%) patients had Hepatitis A, 18 (33.33%) had NANB, 2 (3.7%) had Hepatitis B and 2 (3.7%) concurrent Hepat...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
