Abstract：
:Eighteen cyanotic congenital heart disease (CCHD) and 17 acyanotic congenital heart disease (ACHD) patients in the age range of 2 months to 10 years along with their age and nutrition matched controls were studied for bactericidal, chemotactic and phagocytic functions. Bactericidal and phagocytic functions were significantly depressed in CCHD (p < 0.001) as well as ACHD group (p < 0.001) compared with controls. Chemotactic function was not significantly affected in either. Arterial oxygen content (as a measure of hypoxia) was calculated for each patient and correlated with each immune parameter by univariate linear regression analysis. In CCHD patients linear correlation of borderline significance (p = 0.07) was found between arterial oxygen content and bactericidal activity, but no correlation could be established with phagocytic and chemotactic functions. No correlation was obtained between hematocrit and any of the immune parameters. In ACHD patients no correlations were obtained between the immune parameters and arterial oxygen content or hematocrit. Iron deficiency anemia, known to affect bactericidal function, did not seem to affect the immune parameters in CCHD and ACHD groups. Altered oxygen content of the blood owing to hypoxia in CCHD patients may be an important etiological factor in the genesis of bacteremia and cerebral abscess. The affection of immune functions in ACHD cannot be adequately explained.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Parikh S,Bharucha B,Kamdar S,Kshirsagar Nsubject
Has Abstractpub_date
1993-07-01 00:00:00pages
883-90issue
7eissn
0019-6061issn
0974-7559journal_volume
30pub_type
杂志文章abstract：:This study was conducted in 2006 to assess the current iodine nutriure of the population in Haryana by assessing the urinary iodine excretion levels amongst the school age children between 6-12 years. Altogether 3,019 urine samples were collected from all the 19 districts in Haryana. The urinary iodine was analyzed by...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:The incidence and the factors that influence twinning were studied in six villages of Dholka Taluka, a rural field training centre. The twinning rate was 10.10 per 1000 maternities. The monozygotic and dizygotic twinning rates were 4.53 and 5.56, respectively by applying Weinberg's differential formula. In three fourt...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1990-03-01 00:00:00
abstract：:Two hundred and fifty eight newborn babies were studied for the presence of retinal hemorrhages between 1-3 days of birth. The overall incidence of retinal hemorrhages was found to be 18.9%. It was observed that the incidence of retinal hemorrhages was higher in unassisted vaginal deliveries than in assisted births. A...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1989-02-01 00:00:00
abstract：:Marfan syndrome rarely presents with peripheral artery and pulmonary artery aneurysms. We are presenting a case of a fifteen-year-old boy who presented to us with progressive lower abdominal pulsatile swelling with bruit in the right inguinal region for one month. He had typical marfanoid habitus, though there was no ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2013-05-08 00:00:00
abstract：OBJECTIVE:To assess the safety and reactogenecity of indigenously produced measles vaccine derived from EZ strain. DESIGN:A longitudinal clinical follow up after vaccination. SETTING:Hospital based and home follow up, as required. SUBJECTS:12,470 children, 9 to 15 months old, immunized with measles vaccine of EZ str...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：:We assessed the clinical response and side effects of Ferrous sulfate (FS) and Iron polymaltose complex (IPC) in 118 children with Iron deficiency anemia (IDA). Subjects were randomized to receive therapy with either oral IPC (Group A, n=59) or oral FS (Group B, n=59); all were given elemental iron in three divided do...
journal_title：Indian pediatrics
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2009-10-01 00:00:00
abstract：OBJECTIVE:To study the clinical profile of children with scrub typhus and its association with hemophagocytic lymphohistiocytosis. METHODS:Children presenting with unexplained fever and multi-systemic involvement between May to December 2011 were tested for scrub typhus using IgM ELISA kits. Occurrence of Hemophagocyt...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-014-0470-4
更新日期：2014-08-01 00:00:00
abstract：:Association of rotavirus gastroenteritis with histo-blood group antigens in children younger than 5 years admitted with diarrhea (n=389) was studied. Distribution of blood groups in rotavirus positive (n=96) and rotavirus negative (n=51) diarrhea gastroenteritis cases did not show any susceptibility to any blood group...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2016-07-08 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy and tolerability of intravenous fosphenytoin in children with status epilepticus, and resulting serum total phenytoin levels. METHODS:In this prospective study, 51 children aged less than 18 years received intravenous loading dose of fosphenytoin (18-20 mg/kg). Serum total phenytoin ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-03-15 00:00:00
abstract：:This retrospective analysis documents the usefulness of fiberoptic bronchoscopy in finding the etiology of 56 cases of unresolved atelectasis in infancy, over a two year period (June 2005 to May 2007). Fiberoptic bronchoscopy identified the etiology leading to a revised diagnosis and change in management strategy in 3...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-010-0134-y
更新日期：2010-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the effectiveness of a community oral health awareness program given to mothers through trained community level workers (Junior Public Health Nurses (JPHNs) and Anganwadi workers (AWWs). METHODS:Oral health education materials were prepared based on the findings of a knowledge survey among commun...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:The retrospective study was carried out to examine performance of Pottels height- independent equation compared to Schwartzs height-dependent equation to estimate glomerular filtration rate in 115 children in Indian setting. The Pottels equation performed well compared to updated Schwartz equation (R2=0.94, mean bias ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-017-1001-x
更新日期：2017-01-15 00:00:00
abstract：OBJECTIVE:To evaluate the effect of clofibrate for unconjugated hyperbilirubinemia in neonates. METHODS:A systematic review with meta-analysis of randomized controlled trials or quasi-randomized controlled trials was conducted to evaluate the clofibrate treatment in neonates with unconjugated hyperbilirubinemia. We fo...
journal_title：Indian pediatrics
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s13312-012-0012-x
更新日期：2012-01-01 00:00:00
abstract：:Pediatric coronavirus disease-19 (COVID-19) infection is relatively mild when compared to adults, and children are reported to have a better prognosis. Mortality in children appears rare. Clinical features of COVID-19 in children include fever and cough, but a large proportion of infected children appears to be asympt...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：2020-05-15 00:00:00
abstract：OBJECTIVE:To identify the factors influencing brain injury in infants with congenital heart disease (CHD) after cardiac surgery. METHODS:This retrospective study investigated 103 infants with CHD undergoing cardiac surgery between January 2013 and February 2016. Pre- and postoperative amplitude-integrated electroencep...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-02-15 00:00:00
abstract：:Cord problems at birth were prospectively studied in 12,000 singleton deliveries, of which 258 (2.15%) babies had cord abnormalities. Nearly 32% of these cases had fetal distress and 20.5% had 1 minute Apgar score less than 6. Of the various cord problems nuchal cord was noted in 79.1%, cord prolapse in 12.4% and true...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1992-03-01 00:00:00
abstract：OBJECTIVE:To determine the health-related quality of life in children with cerebral palsy and their families. METHODS:One hundred children (3-10 years of age) receiving regular rehabilitation therapy for cerebral palsy for last 1 year at a Child Development Centrer were enrolled and the Lifestyle assessment questionna...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-014-0414-z
更新日期：2014-05-01 00:00:00
abstract：:Trichotillomania, though uncommon, is one of the causes of unexplained hair loss, especially in children. Three girls in the age group of 4-6 years were observed in our pediatric dermatology clinic to have trichotillomania. In one child, there was co-existent alopecia areata. All were referred to the child guidance cl...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVE:To study the relationship of CSF IL-1 beta and TNF-alpha with free radicals in acute bacterial meningitis (ABM) and to evaluate the clinical outcome in relation to the levels of these cytokines and free radicals in CSF. DESIGN:Prospective with controls. SETTING:Referral unit of a teaching hospital. METHODS...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：OBJECTIVE:To compare the impact of postnatal lactational counseling on the weight gain and frequency of mixed feeding in full term neonates. DESIGN:Observational study. SETTING:Mother-infant pairs were observed in the maternity section of a multispecialty general hospital in Mumbai during two time periods. PARTICIPA...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-015-0678-y
更新日期：2015-07-01 00:00:00
abstract：JUSTIFICATION:Viral encephalitis is an important cause of mortality and morbidity in children. The etiological agents are varied, and physicians treating such children often feel limited by the lack of uniform guidelines on evaluation and management of these critically ill children in resource-constrained settings. PR...
journal_title：Indian pediatrics
pub_type： 杂志文章,实务指引
doi：10.1007/s13312-012-0216-0
更新日期：2012-11-01 00:00:00
abstract：:Intravenously administered rehydration therapy was compared with orally administered rehydration therapy for treating children with diarrhea in a clinical study of 3000 children admitted to the Medical College Hospital, Kottayam, India. Oral rehydration was more effective and safer than intravenously administered flu...
journal_title：Indian pediatrics
pub_type： 临床试验,杂志文章
doi：
更新日期：1978-10-01 00:00:00
abstract：:Capillaria hepatica is a very rare zoonotic infestation which primarily infests rodents and is rarely found in humans. The presenting features are fever of unknown origin, hepatomegaly and peripheral eosinophilia. Liver biopsy remains the cornerstone of diagnosis. Treatment of choice is Albendazole and outcome is gene...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2007-10-01 00:00:00
abstract：:Andersen Tawil syndrome is a rare type of channelopathy characterized by the presence of periodic paralysis, cardiac arrhythmia (prolonged QT interval or ventricular arrhythmia) and distinct dysmorphic abnormalities. It is a type of potassium channelopathy that occurs sporadically or by autosomal dominant inheritance....
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-011-0008-y
更新日期：2011-01-01 00:00:00
abstract：:We report Hemolytic Uremic Syndrome (HUS) induced by Streptococcus pneumoniae in a 20 month-old girl. She responded well to hemodialysis. ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2007-05-01 00:00:00
abstract：OBJECTIVE:To study the etiological profile and patterns of clinical presentation of nephrocalcinosis. METHODS:In this observational study, patients 18 years or younger, referred to the pediatric nephrology clinic with nephrocalcinosis were evaluated for etiology. Symptoms/signs at presentation, estimated glomerular fi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-05-15 00:00:00
abstract：:Clinical needs for new antifungal agents have steadily increased with the rise and alteration in spectrum of invasive mycoses in children and neonates having AIDS, malignancies and undergoing immunosuppressive therapies. Several new options are now available for management of serious fungal infections. The aim of this...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：2009-03-01 00:00:00
abstract：BACKGROUND:Antiphospholipid syndrome is a multisystem auto-immune disorder characterized by arterial or venous thrombosis in children. CASE CHARACTERISTICS:11-year-old child with pneumococcal meningitis also had cerebral sinus vein thrombosis and pulmonary artery segmental thrombosis. OBSERVATION:Pro-thrombotic evalu...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2018-05-15 00:00:00
abstract：BACKGROUND:There is limited literature available on the phenotypic and mutation spectrum of Indian patients with Lysosomal storage disorders (LSD). OBJECTIVE:To elucidate the clinical, biochemical and mutation spectrum and to study the management options in Indian patients with lysosomal storage disorders. DESIGN:Des...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-012-0192-4
更新日期：2012-10-01 00:00:00
abstract：:One hundred and seventy children of chronic seizures with strong clinical suspicion of an underlying intracranial lesion as its cause were studied by Magnetic Resonance Imaging (MRI). Maximum number of patients were between 6-12 years, males outnumbering females. Structural abnormalities were seen in 158 of the 170 pa...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1991-07-01 00:00:00
