Abstract：
OBJECTIVE:To evaluate the profile of children with central diabetes insipidus (DI) and identify factors indicating organic etiology. DESIGN:Retrospective chart review. SETTING:Tertiary referral hospital. SUBJECTS:Fifty-nine children with central DI (40 boys, 19 girls). METHODS:Features of organic and idiopathic central DI were compared using students t test and chi square test. Odds ratio was calculated for factors indicating organic etiology. RESULTS:Diagnosis included post-operative central DI (13, 22%), central nervous system (CNS) malformations (5, 8.6% holoprosencephaly 4 and hydrocephalus 1), histiocytosis (11, 18.6%), CNS pathology (11, 18.6%; craniopharyngioma 3, empty sella 2, germinoma 2, neuro-tuberculosis 2, arachnoid cyst 1 and glioma 1) and idiopathic central DI (19, 32.2%). Children with organic central DI were diagnosed later (7.8+/- 3.1 years against 5.3+/-2.4 years, P=0.03) and had lower height standard deviation score (-2.7+/-1.0 versus -1.0+/- 1.0, P<0.001) compared to idiopathic group. A greater proportion of children with organic central DI had short stature (81.8% against 10.5%, P <0.001, odds ratio 38.25), neurological features (45.5% against 0%, p 0.009) and anterior pituitary hormone deficiency (81.8% against 5.3%, P<0.001, odds ratio 81) compared to idiopathic group. A combination of short stature and onset after five years of age led to discrimination of organic central DI from idiopathic group in all cases. CONCLUSION:Organic central DI should be suspected in children presenting after the age of five years with growth retardation and features of anterior pituitary deficiency.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Bajpai A,Kabra M,Menon PSsubject
Has Abstractpub_date
2008-06-01 00:00:00pages
463-8issue
6eissn
0019-6061issn
0974-7559journal_volume
45pub_type
杂志文章abstract：:One hundred ninety one children below 5 years of age suffering from poliomyelitis were analyzed to find out the immunization status and its correlation with the incidence of poliomyelitis. Effects of age, sex, immunization status and seasonal variation on the morbidity and mortality status were studied. The maximum nu...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1991-06-01 00:00:00
abstract：JUSTIFICATION:Gaucher disease (GD) is amongst the most frequently occurring lysosomal storage disorder in all ethnicities. The clinical manifestations and natural history of GD is highly heterogeneous with extreme geographic and ethnic variations. The literature on GD has paucity of information and optimal management g...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2018-02-15 00:00:00
abstract：:Two hundred and fifty eight newborn babies were studied for the presence of retinal hemorrhages between 1-3 days of birth. The overall incidence of retinal hemorrhages was found to be 18.9%. It was observed that the incidence of retinal hemorrhages was higher in unassisted vaginal deliveries than in assisted births. A...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1989-02-01 00:00:00
abstract：:A 12-year-old male child reported with history of fever for last seven years. Hepatosplenomegaly, hepatic and bone marrow granulomas were the main features. Idiopathic Granulomatous Hepatitis (IGH), a rare syndrome amenable to immunosuppressive therapy was diagnosed. ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2004-06-01 00:00:00
abstract：:In 2017, a 10-year-old girl, who was allegedly raped and impregnated, was denied an abortion on the basis of the Medical Termination of Pregnancy Act 1971. This perspective re-examines this issue while prioritizing the best interest of the child. We recommend that boards should be constituted at district-level hospita...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2018-10-15 00:00:00
abstract：JUSTIFICATION:There is a need to revise/review recommendations regarding existing vaccines in view of current developments in vaccinology. PROCESS:Advisory Committee on Vaccines and Immunization Practices (ACVIP) of Indian Academy of Pediatrics (IAP) reviewed the new evidence, had two meetings, and representatives of ...
journal_title：Indian pediatrics
pub_type： 杂志文章,实务指引
doi：
更新日期：2018-12-15 00:00:00
abstract：:The present study was undertaken to find out the best simple anthropometric parameter for identifying low birth weight babies (LBW). A total of 1000 newborn babies were subjected to anthropometry within 48 hours of life. Birth weight was significantly correlated (p less than 0.001) with thigh circumference (TC), mid-a...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:The skinfold thickness (SFT) was measured in 750 Punjabi newborns at triceps and subscapular sites using a Harpenden's Caliper. It was correlated with various maternal and neonatal factors. SFT increased with increasing gestation but showed a decline after 40 weeks. There was a positive correlation of SFT with birth w...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1991-11-01 00:00:00
abstract：OBJECTIVE:To assess the epidemiological and clinical characteristics of pediatric inpatients with COVID-19, early in the pandemic. METHODS:Clinical and laboratory profile and outcomes were studied for children (aged 1 month - 18 years) presenting between 1 April, 2020 and 20 May, 2020 with positive nasopharyngeal swab...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-10-15 00:00:00
abstract：:The best known muscular dystrophies are X-linked dystrophinopathies. A clinically and genetically heterogeneous group presenting with weakness of the pelvic and shoulder girdles is that of the limb-girdle muscular dystrophies (LGMDs). Sarcoglycanopathies (SGPs) are autosomal recessive LGMDs. We report a rare case of p...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2003-11-01 00:00:00
abstract：:We conducted this study to determine the fatty acid composition of breastmilk of Israeli women and compare it with baby milk substitutes. Samples of mature breast milk, from 29 lactating Israeli Jewish mothers were collected during feedings. Total milk lipids extracts were transmethylated and analyzed by using an impr...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0277-8
更新日期：2013-11-08 00:00:00
abstract：:Eighteen cyanotic congenital heart disease (CCHD) and 17 acyanotic congenital heart disease (ACHD) patients in the age range of 2 months to 10 years along with their age and nutrition matched controls were studied for bactericidal, chemotactic and phagocytic functions. Bactericidal and phagocytic functions were signif...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1993-07-01 00:00:00
abstract：OBJECTIVE:To describe the utility of flexible fiberoptic bronchoscopy for the diagnosis and management in the neonatal ICU. METHODS:A retrospective, medical chart review was conducted in neonates who underwent flexible fiberoptic bronchoscopy over a period of 7 years. Besides demographic data and diagnostic findings, ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2019-07-15 00:00:00
abstract：:Pathologic fractures in children may be due to various causes. Rarely, it may be the presenting symptom of neurofibromatosis. A misdiagnosis of Rickets and Vitamin D supplementation in such a case may wreak havoc in the form of iatrogenic hypervitaminosis D. We report one such case. ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-010-0137-8
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:Glycogen storage disease type VI (GSD-VI) presents with failure to thrive and also fibrosis in some cases, without cirrhosis. CASE CHARACTERISTICS:2½-year-old girl presented with short stature, transaminase elevation and significant fibrosis, suggesting GSD-III. OBSERVATION:A pathogenic mutation in PYGL ge...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-017-1174-3
更新日期：2017-09-15 00:00:00
abstract：:We assessed the clinical response and side effects of Ferrous sulfate (FS) and Iron polymaltose complex (IPC) in 118 children with Iron deficiency anemia (IDA). Subjects were randomized to receive therapy with either oral IPC (Group A, n=59) or oral FS (Group B, n=59); all were given elemental iron in three divided do...
journal_title：Indian pediatrics
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2009-10-01 00:00:00
abstract：:Postictal values of plasma prolactin levels were measured in 15 children with generalized seizures, 8 children with pseudoseizures and 6 control subjects. In patients with generalized seizure, the mean plasma prolactin level was 28.6 +/- 2.3 ng/ml, whereas in patients with pseudoseizures and in controls, its mean valu...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1994-06-01 00:00:00
abstract：:Three hundred and fifty stool samples from patients with acute diarrhea and 30 samples from normal healthy controls were examined for the presence of various parasitic and bacterial enteropathogens by conventional techniques. Cryptosporidium oocysts were detected in 15 out of 350 (4.3%) fecal samples. In 10 cases (2.9...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1991-08-01 00:00:00
abstract：:We report Hemolytic Uremic Syndrome (HUS) induced by Streptococcus pneumoniae in a 20 month-old girl. She responded well to hemodialysis. ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2007-05-01 00:00:00
abstract：:Clinical and hematological data of 9 cases with factor XIII deficiency is highlighted. The age at first bleed ranged from 3 days of life to 1 year. Seven of these 9 cases had bleeding from the umbilicus, 3 had recurrent subcutaneous and muscle hematomas, while 4 cases had CNS bleeds of which 3 expired. Routine coagulo...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：1992-07-01 00:00:00
abstract：:The retrospective study was carried out to examine performance of Pottels height- independent equation compared to Schwartzs height-dependent equation to estimate glomerular filtration rate in 115 children in Indian setting. The Pottels equation performed well compared to updated Schwartz equation (R2=0.94, mean bias ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-017-1001-x
更新日期：2017-01-15 00:00:00
abstract：BACKGROUND:Fetal growth restriction and abnormal Doppler flow studies are commonly associated. Neonatal outcomes are not well known particularly in developing countries, where the burden of the disease is the highest. OBJECTIVE:To determine outcomes of preterm infants with history of absent/reversed end-diastolic umbi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0235-5
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:To study the transcutaneous absorption of traditionally massaged oil in newborns and to specifically compare the effects of (i) essential fatty acid (EFA) rich - safflower oil and (ii) saturated fat rich coconut oil, on fatty acid profiles of massaged babies. DESIGN:A short term randomised controlled study. ...
journal_title：Indian pediatrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2005-10-01 00:00:00
abstract：:Biliary atresia has been commonly reported with cytomegalovirus (CMV) infection. CMV positive patients may present with a later onset however long term outcome is similar to non-CMV patients. There are very few case reports of role of antivirals in CMV and biliary atresia. We treated a 2 month old girl with biliary at...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-012-0092-7
更新日期：2012-06-01 00:00:00
abstract：:This study was conducted to determine the frequency of antinuclear antibodies (ANA) positivity and uveitis in our newly diagnosed juvenile idiopathic arthritis (JIA) patients classified according to International League Against Rheumatology (ILAR) classification criteria. Ninety-two girls and 106 boys, totally 198 chi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2004-10-01 00:00:00
abstract：OBJECTIVE:To describe a novel wrist deformity in b-thalassemia major patients, and their radiographic and magnetic resonance imaging findings. METHODS:30 patients with b-thalassemia major who were noticed to have ulnar deviation at wrist joint were evaluated for previous history of medications, serum ferritin levels, ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2019-01-15 00:00:00
abstract：OBJECTIVE:To assess the efficacy of nasal intermittent positive pressure ventilation with heliox in preterm infants with respiratory distress syndrome. METHODS:Premature infants with mild respiratory distress syndrome requiring non-invasive respiratory support were eligible. Infants were randomly assigned to heliox or...
journal_title：Indian pediatrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s13312-014-0524-7
更新日期：2014-11-01 00:00:00
abstract：:Seven cases of benign form of spinal muscular atrophy were studied to evaluate the importance of detecting hand tremors, muscle fasciculation, evertion of foot and ECG tremors to distinguish these cases from muscular dystrophy. Taken in combination, diagnosis of all the seven cases was possible without the need for ap...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1989-10-01 00:00:00
abstract：OBJECTIVE:To study the relation between maternal overt hypothyroidism and neurodevelopmental outcome of neonates in iodine-deficient region of Northern India (Kashmir Valley). DESIGN:Prospective cohort study. SETTING:Endocrinology department of a tertiary-care hospital. PARTICIPANTS:82 hypothyroid pregnant women wer...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-015-0733-8
更新日期：2015-10-01 00:00:00
abstract：OBJECTIVE:To study the effect of oil massage on growth and neurobehavior in preterm babies less than 1500 g. DESIGN:Randomized Controlled Trial. SETTING:Tertiary level neonatal unit of a teaching hospital. SUBJECTS:Neonates with birth weight <1500 grams, gestation >37 weeks, receiving enteral feeds of at least 100 m...
journal_title：Indian pediatrics
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2005-11-01 00:00:00
