Association Between Metabolic Control and Lipid Parameters in Indian Children with Type 1 Diabetes.

Abstract:

OBJECTIVE:To compare lipid parameters between diabetics and controls and to study association between metabolic control and lipid profile. METHODS:Lipid profile and HbA1c were measured (n=80, 39 boys) in diabetic children [age 10.7(3.4) y] and 54 controls, tests repeated after 1 year (in 45 diabetics). RESULTS:Diabetic children had higher mean (SD) LDL-C [95.3(27.7) vs 84.5(26.4) mg/dL], lower HDL-C [48.2 (13.1) vs 53.1(11.9) mg/dl]. Moderate physical activity (P=0.014) protected against high LDL-C levels. HbA1c (P=0.00) predicted total and LDL-C levels. At 1year, 63% showed reduced LDL-C with improving HbA1c; 72% showed increased LDL-C with deteriorated HbA1c. CONCLUSION:Improving metabolic control is cardinal to reduce cardiometabolic risk; physical activity is beneficial.

journal_name

Indian Pediatr

journal_title

Indian pediatrics

authors

Parthasarathy L,Chiplonkar S,Khadilkar V,Khadilkar A

doi

10.1007/s13312-016-0787-2

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

39-41

issue

1

eissn

0019-6061

issn

0974-7559

journal_volume

53

pub_type

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