Abstract:
OBJECTIVE:Analyze the profile and outcome of children with rhabdomyosarcoma from a pediatric-oncology unit. DESIGN:Retrospective analysis of case records over 23 years (1990-2012). Setting:Government-run, tertiary-care, university hospital in Northern India. PARTICIPANTS:159 children (<12-years) with a diagnosis of rhabdomyosarcoma were enrolled. The median age was 4 years; 13% were infants. MAIN OUTCOME MEASURE:Five-year event free survival. RESULTS:The median symptom interval was 2-months. Head and neck region was the most frequent site (44%), followed by tumors in the extremity (15.7%). The majority (67%) of the tumors were located at 'unfavorable' sites; 68% were >5 cm in size. The most frequent (58%) pathological subtype was embryonal. Treatment was based on the 'Intergroup Rhabdomyosarcoma Study (IRS) Group' risk-stratification. 33% were 'low-risk' children, 11% were 'high-risk'. Treatment-refusal (18%) and abandonment (33%) were major impediments. The median ± SE five-year event free survival of those taking treatment was 43.6 ± 6%. Conclusion:Large sized tumors, tumors at unfavorable locations, and treatment refusal/abandonment contributed to inferior outcome in children with rhabdomyosarcoma.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Bansal D,Das A,Trehan A,Kapoor R,Panda NK,Srinivasan R,Panda NK,Srinivasan R,Kakkar N,Sodhi KS,Saxena AK,Narasimha Rao KLdoi
10.1007/s13312-017-1164-5subject
Has Abstractpub_date
2017-09-15 00:00:00pages
735-738issue
9eissn
0019-6061issn
0974-7559journal_volume
54pub_type
杂志文章abstract::This paper explores the relationships between maternal weight, height and poor pregnancy outcome using a data set from a case-control study of low birth weight (LBW) and perinatal mortality in Ahmedabad, India. Maternal height and weights were compared between mothers of 611 perinatal deaths, 644 preterm-LBW, and 1465...
journal_title:Indian pediatrics
pub_type: 杂志文章,多中心研究
doi:
更新日期:1994-10-01 00:00:00
abstract::The clinical, laboratory and therapeutic data of patients with diarrhea in Human immunodeficiency virus (HIV) antibody positive, immunocompromised and immunocompetent individuals were studied especially to look for prevalence of intestinal coccidiosis. During a study period of one decade, Isospora belli were identifie...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND:Multiple pituitary hormone deficiency and Turner syndrome have overlapping features in peripubertal girls and is a diagnostic challenge. CASE CHARACTERISTICS:16-year-old girl having Turner phenotype undergoing evaluation for severe short stature and pubertal arrest. OBSERVATION:45,X karyotype, and multiple...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-015-0721-z
更新日期:2015-09-01 00:00:00
abstract:: ...
journal_title:Indian pediatrics
pub_type: 评论,社论
doi:
更新日期:2018-11-15 00:00:00
abstract:OBJECTIVE:To assess the epidemiological and clinical characteristics of pediatric inpatients with COVID-19, early in the pandemic. METHODS:Clinical and laboratory profile and outcomes were studied for children (aged 1 month - 18 years) presenting between 1 April, 2020 and 20 May, 2020 with positive nasopharyngeal swab...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-10-15 00:00:00
abstract::A 12-year-old boy had undergone total gastrectomy for gastric volvulus with subsequent severe weight loss and malnutrition. A Hunt-Lawrence pouch was constructed to provide gastric reservoir capacity and the child at 4-years follow-up has regained near normal weight for his age and is attending to school and other act...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2003-03-01 00:00:00
abstract::Antimicrobial resistance has become a global menace. As the resistance patterns and numbers are progressively increasing, it has become a major cause of morbidity and mortality in hospitalized patients, especially children. Efforts are being put world-over to curb the rising resistance by various means, especially by ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-016-0839-7
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVE:To evaluate adiponectin levels in children and adolescents with type I diabetes, and their relationship to long term complications. DESIGN:Cross sectional. SETTING:Tertiary referral hospital, Cairo, Egypt. PARTICIPANTS:Thirty children and adolescents with type I diabetes mellitus, classified into complicat...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-012-0041-5
更新日期:2012-04-01 00:00:00
abstract::Salmonella senftenberg was isolated from the stools of 35 newborns between June, 1987 and September, 1988. Twenty nine (82.8%) babies were preterms and twenty six (74%) babies were less than 2,000 grams in weight. All of them were symptomatic within 6 days of life, 74.3% (26) within 4 days. All of them had loose stool...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1990-02-01 00:00:00
abstract:: ...
journal_title:Indian pediatrics
pub_type: 信件
doi:
更新日期:2019-02-15 00:00:00
abstract::A randomized double blind placebo controlled trial was carried out to study the effect of phenobarbitone (PB) in preventing recurrences of simple and atypical febrile convulsions among children in the age group 6 months to 6 years. Children with simple febrile convulsions were randomly allocated to receive either phen...
journal_title:Indian pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1993-05-01 00:00:00
abstract::Marfan syndrome rarely presents with peripheral artery and pulmonary artery aneurysms. We are presenting a case of a fifteen-year-old boy who presented to us with progressive lower abdominal pulsatile swelling with bruit in the right inguinal region for one month. He had typical marfanoid habitus, though there was no ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2013-05-08 00:00:00
abstract:OBJECTIVE:To investigate association between dietary habits and asthma severity in children. DESIGN:Cross-sectional study. SETTING:Two teaching hospitals in Brazil. PARTICIPANTS:Cases (n=268) were children (3-12yr) with persistent asthma and age-matched controls (n=126) were those with intermittent asthma. MAIN OUT...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-015-0561-x
更新日期:2015-01-01 00:00:00
abstract:: ...
journal_title:Indian pediatrics
pub_type: 评论,杂志文章
doi:
更新日期:2019-09-15 00:00:00
abstract::The incidence and the factors that influence twinning were studied in six villages of Dholka Taluka, a rural field training centre. The twinning rate was 10.10 per 1000 maternities. The monozygotic and dizygotic twinning rates were 4.53 and 5.56, respectively by applying Weinberg's differential formula. In three fourt...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1990-03-01 00:00:00
abstract:OBJECTIVE:To assess the prevalence of asthma and wheeze and factors associated with it in children aged 6-7 and 13-14 years. METHOD:School based, prospective survey using self/parental reporting of occurrence of asthma or wheeze on pre-designed questionnaire. RESULTS:Out of 112 schools, 17 and 15 schools were randoml...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVE:To compare the effect of withholding maintenance phenobarbitone on breakthrough seizures. DESIGN:A double blind randomized controlled trial. SETTING:Level II neonatal intensive care unit (NICU) of a teaching hospital in Northern India. PARTICIPANTS:152 term and near term neonates (34 weeks of gestation age...
journal_title:Indian pediatrics
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2016-12-15 00:00:00
abstract::A case of idiopathic hypereosinophilic syndrome who had an unusual presentation in the form of pericardial effusion is being presented here. The child initially responded to corticosteroids but could not maintain normal eosinophil counts on tapering of steroids. Therefore he was put on hydroxyurea and low dose of ster...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::Fifty two mother-infant pairs were studied. Twenty six of these were delivered by the normal vaginal route (NVD group) and twenty six by Cesarean section (CS group). The NVD babies were roomed in with their mothers soon after birth whereas the CS babies had a mean separation of 2.8 +/- 1.0 days. The mother baby intera...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:To describe the clinical characteristics and outcome of Indian children infected with 2009 H1N1 influenza virus. STUDY DESIGN:Retrospective chart review. SETTING:Outpatient department and hospitalized patients in a tertiary care hospital. METHODS:Clinical details of 85 children (positive for the 2009 H1N1 ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-011-0085-y
更新日期:2011-05-01 00:00:00
abstract::Fifty seven male children between ages of 10-16 years engaged in the brassware industry at Moradabad in Northern India were studied for occupational morbidity. The finding were compared with those obtained in the children (n = 29) engaged in other ancillary units which did not involve exposure to the metal fumes and d...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-02-01 00:00:00
abstract:OBJECTIVE:To compare the performance of respiratory rate and other clinical signs against pulse oximetry for predicting hypoxia in children with Severe pneumonia/Very severe disease as per Integrated Management of Neonatal and Childhood Illness (IMNCI) classification. DESIGN:Cross-sectional study. SETTING:Pediatric e...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-017-1163-6
更新日期:2017-09-15 00:00:00
abstract::No clear operational definition of 'Community Participation' has emerged over the last decade of experimentation. One reason is the markedly contrasting perspectives that exist at different levels such as Aid Agencies, Ministry of Health, Government Health Programmes and Non-Government Organizations (NGOs). A more pra...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
abstract:OBJECTIVE:To assess the safety and reactogenecity of indigenously produced measles vaccine derived from EZ strain. DESIGN:A longitudinal clinical follow up after vaccination. SETTING:Hospital based and home follow up, as required. SUBJECTS:12,470 children, 9 to 15 months old, immunized with measles vaccine of EZ str...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract::Growth monitoring (GM) in India is a strategy to detect early growth retardation, promote optimum growth, create awareness about growth among mothers, enhance delivery of primary health care, and identify those at risk of malnutrition. Anthropometric measures include weight, height, mid-upper arm circumference, chest ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1994-02-01 00:00:00
abstract:OBJECTIVE:To study the association between common AIDS restriction genes and slow disease progression among perinatally-infected children in India. METHODS:ART-naïve children were identified and selected host factors including CCR5-∆32, SDF1-3'A, CCR5-59029G, HLA-B*27, B*57 were studied using allele-specific PCR-RFLP ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-014-0505-x
更新日期:2014-10-01 00:00:00
abstract::Meropenem is a new carbapenem antibacterial agent with wide spectrum of activity against gram-negative, gram-positive and anaerobic organisms. It is stable against most beta-lactamases produced by gram-negative bacteria and has greatest utility in treating severe infections in hospitalized children. It has good CSF pe...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2005-05-01 00:00:00
abstract::The prevalence of Attention deficit hyperactivity disorder was estimated in 500 adolescents using Conners' parents and teachers rating scales. Thirty six (7.2%) adolescents had positive scores on both the scales. The parents and teachers also completed a Diagnostic and Statistical Manual-IV based questionnaire which s...
journal_title:Indian pediatrics
pub_type: 信件
doi:10.1007/s13312-014-0350-y
更新日期:2014-02-01 00:00:00
abstract::We prospectively studied the effect of oral paracetamol in closing hemodynamically significant Patent ductus arteriosus in preterm infants (gestational age <32 weeks) where Ibuprofen was contraindicated. 29 of 40 neonates (72.5%) showed successful response while 11 (29.5%) failed to show any response. No major complic...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Inflammatory pseudo tumor, a rare non-neoplastic lesion, commonly presents as slow growing solid lesion in the lung, but many extra-pulmonary locations have been described. CASE CHARACTERISTICS:A 4-year-old girl who presented with respiratory distress due to massive pleural effusion. Computed tomography rev...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2018-04-15 00:00:00