Abstract：
:Increasing availability of DNA based tests in clinical practice has lead to widespread debate on the ethical issues involved. The wider usage of these tests in children has raised many questions regarding the ethics, validity of the request and its effects on childs psychosocial well-being. Though there have been much discussion with many studies attempting to address the issue, there is no consensus. Formulation of guidelines has been hampered by the diversity of tests available for varied indications and lack of research studying the effects of testing in children over a time. Some tests have valid indications with proven benefits over harms while others have less clear justification. We attempt to address this issue with the intent to sensitize the caregivers regarding various aspects to be considered before offering any genetic tests in children.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Phadke S,Gowda Mdoi
10.1007/s13312-013-0228-4subject
Has Abstractpub_date
2013-09-01 00:00:00pages
823-7issue
9eissn
0019-6061issn
0974-7559journal_volume
50pub_type
杂志文章abstract：OBJECTIVE:To compare the effectiveness of tepid sponging and antipyretic drug versus only antipyretic drug among febrile children. DESIGN:Randomized controlled trial. SETTING:Tertiary care hospital. PARTICIPANTS:150 children 6 mo - 12 yr age with axillary temperature 101F. INTERVENTION:Tepid sponging and antipyreti...
journal_title：Indian pediatrics
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2009-02-01 00:00:00
abstract：:We report a 71/2-year-boy with disseminated systemic cryptococcosis. Although other species have been incriminated, this appears to be the first report of Cryptococcus humicolus. The child was HIV negative. He was treated with amphotericin B and fluconazole with intensive supportive care. The child responded after 6 w...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2004-11-01 00:00:00
abstract：OBJECTIVE:To investigate association between dietary habits and asthma severity in children. DESIGN:Cross-sectional study. SETTING:Two teaching hospitals in Brazil. PARTICIPANTS:Cases (n=268) were children (3-12yr) with persistent asthma and age-matched controls (n=126) were those with intermittent asthma. MAIN OUT...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-015-0561-x
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVE:To determine the survival of children =18 y, treated with immunosuppressive therapy (IST) using equine antithymocyte globulin (e-ATG) and cyclosporine (CsA). DESIGN:Prospective data entry as per a specified format. SETTING:Tertiary care hospital. PATIENTS:From January 1998 to December 2009, 40 children wer...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-012-0086-5
更新日期：2012-05-01 00:00:00
abstract：:We studied the ability of B-type natriuretic peptide (BNP) in predicting mortality among 86 in-patients with severe acute malnutrition presenting with co-morbidity, and found that cut-off level of BNP ≥201 pg/mL in Receiver operating characteristics curve [AU-ROC 0.96 (95% CI 0.92,1.003, P<0.0001)] had high discrimina...
journal_title：Indian pediatrics
pub_type： 信件
doi：
更新日期：2020-04-15 00:00:00
abstract：:Madhya Pradesh has made remarkable progress in facility based management of severe acute malnutrition, and has developed a model that is being replicated in many states. India has uniquely high prevalence of both stunting and wasting, implying that both severe acute malnutrition and severe chronic malnutrition co-exis...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-014-0341-z
更新日期：2014-02-01 00:00:00
abstract：Context:Infantile colic is self-limiting condition but it can be a cause of anxiety for parents and challenge for doctors. The challenge for the doctors lies in correct identification of the condition and appropriate management. The objective of this review article is to summarize the pathophysiology, treatment options...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：2018-11-15 00:00:00
abstract：OBJECTIVE:To study the clinical spectrum and management of choledochal cyst in children below 12 years of age. DESIGN:Descriptive study. SETTING:Tertiary care hospital. METHODS:Twenty three children with choledochal cysts were managed between January 1991 to September 1997 and their clinical details, investigations ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1998-07-01 00:00:00
abstract：BACKGROUND:Fetal growth restriction and abnormal Doppler flow studies are commonly associated. Neonatal outcomes are not well known particularly in developing countries, where the burden of the disease is the highest. OBJECTIVE:To determine outcomes of preterm infants with history of absent/reversed end-diastolic umbi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0235-5
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:To identify the pattern of congenital heart defects (CHD) in children with Down Syndrome (DS) in an Omani population, and compare it with CHD in children without DS and with historical cohorts from populations with low prevalence of consanguinity. SETTING:Open-access Paediatric Echocardiography Clinic at Sul...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2003-05-01 00:00:00
abstract：OBJECTIVE:To assess the prevalence of asthma and wheeze and factors associated with it in children aged 6-7 and 13-14 years. METHOD:School based, prospective survey using self/parental reporting of occurrence of asthma or wheeze on pre-designed questionnaire. RESULTS:Out of 112 schools, 17 and 15 schools were randoml...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2004-12-01 00:00:00
abstract：: ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2018-12-15 00:00:00
abstract：BACKGROUND:High bilirubin level is toxic to developing brain and auditory system but the current debate surrounds the toxicity of bilirubin in healthy term infants. METHODS:Longitudinal observational study to find BERA abnormalities in term newborns with isolated hyperbilirubinemia of 20 mg/dL and more and to follow u...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-014-0346-7
更新日期：2014-02-01 00:00:00
abstract：:The Retinopathy of Prematurity (ROP) epidemic is no more confined to metro cities and has spread to interior states including Eastern India. There is hardly any published data available on the subject, including the incidence and profile of babies with ROP, screening experience with binocular indirect ophthalmoscope a...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2016-11-07 00:00:00
abstract：:The study population included 110 term healthy small-for-gestational age (SGA) infants having a blood sugar of > 30 mg/dl at the age of < 30 minutes. They were randomized into two groups; (a) Group I (study group) received sugar-fortified milk formula and (b) Group II (control group) received standard milk formula. A ...
journal_title：Indian pediatrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1992-11-01 00:00:00
abstract：:Association of rotavirus gastroenteritis with histo-blood group antigens in children younger than 5 years admitted with diarrhea (n=389) was studied. Distribution of blood groups in rotavirus positive (n=96) and rotavirus negative (n=51) diarrhea gastroenteritis cases did not show any susceptibility to any blood group...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2016-07-08 00:00:00
abstract：OBJECTIVE:To evaluate the effect of canakinumab on growth parameters of patients with autoinflammatory diseases. METHODS:This retrospective study included Colchicine resistant familial Mediterranean fever (FMF), Mevalonate kinase deficiency (MKD), Tumor necrosis factor receptor-associated periodic fever syndrome (TRAP...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-07-15 00:00:00
abstract：:We performed a retrospective study of hospital records of children younger than 14 years with ocular trauma seen at our center in Sao Paulo, Brazil, between 2011 and 2012. From the total number of cases, 224 (89.2%) could be easily avoided. Accidents occurred with 5 children under 1 year of age; with one baby as young...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-12-26 00:00:00
abstract：:Pulmonary manifestations of sarcoidosis are common and may be initially confused with other common diseases like tuberculosis. We report an 11 yr old girl who presented with chronic cough, low grade fever, recent exposure to tuberculosis and hilar lymphadenopathy. She was provisionally diagnosed as pulmonary tuberculo...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND:Outcome of pseudomonas enteric fever is unpredictable as multiple systemic lethal complications occur abruptly. CASE CHARACTERISTICS:A 9-month-old girl with multiple ileal perforations, leukocoria, ecthyma gangrenosum, hemiplegia and a perforated ulcer in the soft palate. Blood culture suggested Pseudomonas...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-015-0741-8
更新日期：2015-10-01 00:00:00
abstract：OBJECTIVES:To find the relationship between Helicobacter pylori infection and iron deficiency anemia in school-aged children. METHODS:71 children with dyspepsia, epigastric and vague abdominal pain attending a tertiary medical center in Iran underwent upper gastrointestinal endoscopy and were investigated for H. Pylor...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2019-05-15 00:00:00
abstract：OBJECTIVE:To calculate and compare costs of neonatal intensive care by micro-costing and gross-costing methods. METHODS:The costs of resources of a tertiary care neonatal intensive care unit were estimated by the two methods to arrive at specific costs per diagnosis related categories for 33 neonates followed-up prosp...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-014-0376-1
更新日期：2014-03-01 00:00:00
abstract：:Hospital acquired enteric infections were investigated by studying 3138 children under 5 years of age who were admitted without diarrhea in nine medical words of a pediatric hospital, Calcutta during the period between March and September 1987. Three hundred and twenty (10.2%) children developed nosocomial diarrhea du...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1993-02-01 00:00:00
abstract：:No clear operational definition of 'Community Participation' has emerged over the last decade of experimentation. One reason is the markedly contrasting perspectives that exist at different levels such as Aid Agencies, Ministry of Health, Government Health Programmes and Non-Government Organizations (NGOs). A more pra...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1989-11-01 00:00:00
abstract：OBJECTIVE:To assess efficacy and safety of High flow nasal cannula therapy (HFNC) as primary mode of treatment for children with respiratory distress. METHODS:Consecutive patients (1 mo-16 years) with respiratory distress were assessed for respiratory clinical score, COMFORT score and saturation to FiO2 (SF) ratio. R...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2021-01-15 00:00:00
abstract：:A retrospective analysis was carried out to identify factors associated with delay in diagnosis of Kawasaki disease in a tertiary care pediatric hospital setting in Chennai, India. Over a period of 2 years, a total of 37 cases were studied. The cases were divided into Early Diagnosis Group (EDG) and Delayed Diagnosis ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-012-0130-5
更新日期：2012-08-01 00:00:00
abstract：OBJECTIVE:To study the etiological profile and patterns of clinical presentation of nephrocalcinosis. METHODS:In this observational study, patients 18 years or younger, referred to the pediatric nephrology clinic with nephrocalcinosis were evaluated for etiology. Symptoms/signs at presentation, estimated glomerular fi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-05-15 00:00:00
abstract：:Two hundred and forty four girls with different hemoglobin levels were selected, of which forty-one were non-anemic. The rest were graded as mildly, moderately or severely anemic and supplemented with 60 mg of iron daily or twice weekly for twelve weeks. There was no significant difference in the increase in hemoglobi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2003-12-01 00:00:00
abstract：:We report a case of primary hyperparathyroidism associated with prolonged hungry syndrome (HBS) after parathyroid adenomectomy in a 10-year-old girl. Bone mineral density (BMD) revealed severe loss of cancellous BMD. Overt bone disease, high alkaline phosphatase, decreased cancellous BMD and a large adenoma can be use...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2009-02-01 00:00:00
abstract：:Current Medical training in India is generally didactic and pedagogical, and often does not systematically prepare newly graduated doctors to be competent, confident and compassionate. After much deliberation, the Medical Council of India (MCI) has recently introduced a new outcome-driven curriculum for undergraduate ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-10-15 00:00:00
