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Using Epigenetic Reprogramming to Treat Pediatric Brain Cancer.

Abstract：

:In this issue of Cancer Cell, Nagaraja et al. dissect the molecular mechanisms underlying therapeutic responses to transcriptional disruptors in the fatal pediatric brain tumor, diffuse intrinsic pontine glioma (DIPG). Moreover, they identify super-enhancers mediating these effects, highlighting how normal brain developmental programs can be hijacked in cancer.

journal_name

Cancer Cell

journal_title

Cancer cell

authors

Chheda MG,Gutmann DH

doi

10.1016/j.ccell.2017.04.008

subject

Has Abstract

pub_date

2017-05-08 00:00:00

pages

609-611

issue

5

eissn

1535-6108

issn

1878-3686

pii

S1535-6108(17)30163-0

journal_volume

31

pub_type

评论,杂志文章

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