Gluing Proteins for Targeted Degradation.

Abstract:

:Targeted protein degradation is an emerging technology for drug development. An article published in Nature reported a novel mechanism of targeted protein degradation triggered by small-molecule-induced polymerization of the oncogenic transcription factor BCL6.

journal_name

Cancer Cell

journal_title

Cancer cell

authors

Naito M,Murata S

doi

10.1016/j.ccell.2020.12.020

subject

Has Abstract

pub_date

2021-01-11 00:00:00

pages

19-21

issue

1

eissn

1535-6108

issn

1878-3686

pii

S1535-6108(20)30668-1

journal_volume

39

pub_type

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