Detection of Serum Antibodies to Hepatitis E Virus Based on HEV Genotype 3 ORF2 Capsid Protein Expressed in Nicotiana benthamiana.

abstract：BACKGROUND:We evaluated the performance of four commercial nucleic acid amplification tests (NAATs: Xpert C. difficile, BD MAX Cdiff, IMDx C. difficile for Abbott m2000, and Illumigene C. difficile) for direct and rapid detection of Clostridium difficile toxin genes. METHODS:We compared four NAATs on the same set of 3...

journal_title：Annals of laboratory medicine

authors： Shin BM,Yoo SM,Shin WC

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Macrophage colony-stimulating factor (M-CSF), matrix metalloproteinase-9 (MMP-9), and its specific tissue inhibitor - tissue inhibitor of metalloproteinases-1 (TIMP-1) may play an important role in the pathogenesis and spread of cancer. We investigated the plasma levels of M-CSF, MMP-9, and TIMP-1 in compari...

journal_title：Annals of laboratory medicine

authors： Ławicki S,Głażewska EK,Sobolewska M,Będkowska GE,Szmitkowski M

更新日期：2016-05-01 00:00:00

abstract：:Reliable reference intervals for sex hormones are indispensable in evaluations of the hypothalamo-pituitary-gonadal axis. This study established reference intervals for estradiol, progesterone, luteinizing hormone, follicle-stimulating hormone, and prolactin with the immunoassay platforms Advia Centaur and Immulite 20...

journal_title：Annals of laboratory medicine

authors： Schüring AN,Kelsch R,Pierściński G,Nofer JR

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:With the advent of sodium glucose co-transporter 2 inhibitors to control glucose and treat diabetes, laboratory data aided by either timed or spot glucose levels in the urine could be used as an alternative marker of drug response. The aim of this study was to assess the agreement between overnight urinary g...

journal_title：Annals of laboratory medicine

authors： Kim SR,Lee YH,Lee SG,Lee SH,Kang ES,Cha BS,Lee HC,Kim JH,Lee BW

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Duffy (FY) blood group genotyping is important in transfusion medicine because Duffy alloantibodies are associated with delayed hemolytic transfusion reactions and hemolytic disease of the fetus and newborn. In this study, FY allele frequencies in Thai blood donors were determined by in-house PCR with sequen...

journal_title：Annals of laboratory medicine

authors： Nathalang O,Intharanut K,Siriphanthong K,Nathalang S,Kupatawintu P

更新日期：2015-11-01 00:00:00

abstract：:As various linezolid resistance mechanisms have been identified in methicillin-resistant Staphylococcus aureus (MRSA), we investigated the molecular characteristics of MRSA with elevated linezolid minimum inhibitory concentrations (MICs), using the VITEK 2 system (bioMérieux, Marcy-l'Étoile, France). Twenty-seven MRSA...

journal_title：Annals of laboratory medicine

authors： Yoo IY,Kang OK,Shim HJ,Huh HJ,Lee NY

更新日期：2020-01-01 00:00:00

abstract：:The platelet-to-lymphocyte ratio (PLR) has emerged as an informative marker revealing shifts in platelet and lymphocyte counts due to acute inflammatory and prothrombotic states. PLR has been extensively examined in neoplastic diseases accompanied by immune suppression and thrombosis, which can be predicted by combine...

journal_title：Annals of laboratory medicine

authors： Gasparyan AY,Ayvazyan L,Mukanova U,Yessirkepov M,Kitas GD

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Mutations in calreticulin (CALR) have been reported to be key markers in the molecular diagnosis of myeloid proliferative neoplasms. In most previous reports, CALR mutations were analyzed by using Sanger sequencing. Here, we report a new, rapid, and convenient system for screening CALR mutations without sequ...

journal_title：Annals of laboratory medicine

authors： Jeong JH,Lee HT,Seo JY,Seo YH,Kim KH,Kim MJ,Lee JH,Park J,Hong JS,Park PW,Ahn JY

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Neutrophil gelatinase-associated lipocalin (NGAL) is a useful biomarker for acute kidney injury (AKI) prediction. However, studies on whether using both plasma NGAL (PNGAL) and urine NGAL (UNGAL) can improve AKI prediction are limited. We investigated the best approach to predict AKI in high-risk patients wh...

journal_title：Annals of laboratory medicine

authors： Yi A,Lee CH,Yun YM,Kim H,Moon HW,Hur M

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The clindamycin-resistant erythromycin-susceptible (CRES) phenotype is rare in Streptococcus agalactiae (group B streptococci). We aimed to determine the molecular characteristics of CRES S. agalactiae using whole genome sequencing (WGS). METHODS:Sixty-six S. agalactiae isolates obtained from blood (N=26), ...

journal_title：Annals of laboratory medicine

authors： Takahashi T,Maeda T,Lee S,Lee DH,Kim S

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:The emergence of fosfomycin resistance and extended-spectrum β-lactamase (ESBL) genes is a serious threat to public health and a new challenge in shigellosis treatment. The purpose of this study was to identify fosfomycin resistance and characterize β-lactamase genes in fos-carrying isolates of Shigella flex...

journal_title：Annals of laboratory medicine

authors： Liu Y,Cheng Y,Yang H,Hu L,Cheng J,Ye Y,Li J

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Although Th2 immune activation is predominant in allergic diseases, neopterinlevels and indoleamine 2,3-dioxygenase (IDO)-1 activity (kynurenine:tryptophan ratio), which reflect Th1 immune activity, increase with interferon-gamma (IFN-γ) stimulation. We investigated neopterin, tryptophan, and kynurenine leve...

journal_title：Annals of laboratory medicine

authors： Ünüvar S,Erge D,Kılıçarslan B,Gözükara Bağ HG,Çatal F,Girgin G,Baydar T

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Clarithromycin, amoxicillin, metronidazole, tetracycline, and levofloxacin have been commonly used for the eradication of Helicobacter pylori. We compared the change in antibiotic resistance of H. pylori strains during two separate periods and investigated the effect of antibiotic resistance on H. pylori era...

journal_title：Annals of laboratory medicine

authors： An B,Moon BS,Kim H,Lim HC,Lee YC,Lee G,Kim SH,Park M,Kim JB

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Differentiation of atypical pathogens is important for community-acquired pneumonia (CAP). In this study, we compared sputum and nasopharyngeal swabs (NPS) for use in detection of Mycoplasma pneumoniae (MP), Chlamydophila pneumoniae (CP), and Legionella pneumophila (LP), using Seeplex PneumoBacter ACE Detect...

journal_title：Annals of laboratory medicine

authors： Cho MC,Kim H,An D,Lee M,Noh SA,Kim MN,Chong YP,Woo JH

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare inherited disorder characterized by infantile-onset macrocephaly, slow neurologic deterioration, and seizures. Mutations in the causative gene, MLC1, are found in approximately 75% of patients and are inherited in an autosomal recessi...

journal_title：Annals of laboratory medicine

authors： Choi SA,Kim SY,Yoon J,Choi J,Park SS,Seong MW,Kim H,Hwang H,Choi JE,Chae JH,Kim KJ,Kim S,Lee YJ,Nam SO,Lim BC

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Although single antigen bead assays (SAB) are approved qualitative tests, the median fluorescence intensity (MFI) values obtained from SAB are frequently used in combination with quantitative significances for diagnostic purposes. To gauge the reproducibility of SAB results, we assessed the interlaboratory v...

journal_title：Annals of laboratory medicine

authors： Oh EJ,Park H,Park KU,Kang ES,Kim HS,Song EY

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Clopidogrel is one of the most commonly used anti-platelet agents in cardiovascular diseases. We analyzed the relationship between the platelet function analyzer (PFA)-200 P2Y (INNOVANCE PFA-200 System, Siemens Healthcare, Germany) results and occurrence of major adverse cardiac events (MACEs) in Korean pati...

journal_title：Annals of laboratory medicine

authors： Lim HH,Li S,An GD,Woo KS,Kim KH,Kim JM,Kim MH,Han JY

更新日期：2018-09-01 00:00:00

abstract：:We aimed to observe antimicrobial resistance patterns and integron carriage of Escherichia coli isolates causing community-acquired infections. Two hundred sixty-eight E. coli strains were obtained from outpatients with various infections at different polyclinics at the 82nd Year of State Hospital in Rize, Turkey. Sus...

journal_title：Annals of laboratory medicine

authors： Copur-Cicek A,Ozgumus OB,Saral A,Sandalli C

更新日期：2014-03-01 00:00:00

abstract：:Myocardial infarction (MI) is the leading cause of death in the developed world. Biomarkers have an essential role in diagnosis, risk stratification, guiding management and clinical decision making in the setting of patients presenting with signs and symptoms of MI. Cardiac troponin (cTn) rose to prominence during the...

journal_title：Annals of laboratory medicine

authors： Christenson E,Christenson RH

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:The impact of HLA and KIR ligand mismatching on the outcome of hematopoietic stem cell transplantation (HSCT) remains unclear. Previous reports have identified considerable ethnic differences in the impact of HLA and KIR ligand mismatches, as well as KIR ligand status, on HSCT; however, to date, no data has ...

journal_title：Annals of laboratory medicine

authors： Park H,Rho EY,In JW,Kim I,Yoon SS,Park S,Shin S,Park KU,Song EY

更新日期：2015-01-01 00:00:00

abstract：:Changes in microparticles (MP) from red blood cell (RBC) concentrates in the context of irradiation have not been investigated. The aim of this study was to evaluate how irradiation affects the number of MPs within transfusion components. Twenty RBC concentrates, within 14 days after donation, were exposed to gamma ra...

journal_title：Annals of laboratory medicine

authors： Cho CH,Yun SG,Koh YE,Lim CS

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:We developed a single-color multitarget flow cytometry (SM-FC) assay, a single-tube assay with graded mean fluorescence intensities (MFIs). We evaluated the repeatability of SM-FC, and its correlation with multicolor flow cytometry (MFC), to assess its application as a routine FC assay. METHODS:We selected ...

journal_title：Annals of laboratory medicine

authors： Park J,Han K

更新日期：2012-05-01 00:00:00

abstract：:Coagulase-negative staphylococci (CoNS) are reported to be the leading cause of nosocomial bloodstream infections. Staphylococcus pettenkoferi is a novel member of CoNS that was first isolated from the human blood and bursitis wound in 2002. We have reported cases of 6 S. pettenkoferi strains isolated from blood speci...

journal_title：Annals of laboratory medicine

authors： Park S,Chung HS,Lee M

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:The Automated Fluorescent Immunoassay System (AFIAS) rotavirus assay (Boditech Med Inc., Chuncheon, Korea) is a new rapid antigen test for rotavirus detection. We evaluated the performance of this assay for detecting rotaviruses and their specific genotypes in clinical stool samples. METHODS:AFIAS rotavirus...

journal_title：Annals of laboratory medicine

authors： Kim JS,Lee SK,Ko DH,Hyun J,Kim HS

更新日期：2019-01-01 00:00:00

abstract：:Guidelines recommend that clinical laboratories perform phenotypic tests (nitrocefin-based test and penicillin 10-U [P10] or 1-U [P1] zone edge tests) to detect penicillinase in Staphylococcus aureus isolates. This study aimed to assess the prevalence of blaZ encoding penicillinase and perform various phenotypic tests...

journal_title：Annals of laboratory medicine

authors： Takayama Y,Tanaka T,Oikawa K,Fukano N,Goto M,Takahashi T

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:High-sensitivity cardiac troponin I (hs-cTnI) and the soluble isoform of suppression of tumorigenicity 2 (sST2) are useful prognostic biomarkers in acute coronary syndrome (ACS). The aim of this study was to test the short term prognostic value of sST2 compared with hs-cTnI in patients with chest pain. METH...

journal_title：Annals of laboratory medicine

authors： Marino R,Magrini L,Orsini F,Russo V,Cardelli P,Salerno G,Hur M,Di Somma S,GREAT NETWORK.

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:The gold standard for antinuclear antibody (ANA) screening is the indirect immunofluorescence (IIF) assay with human epithelial cells (HEp-2). However, a number of substantial disadvantages of manual IIF assays have highlighted the need for the automation and standardization of fluorescent ANA (FANA) testing...

journal_title：Annals of laboratory medicine

authors： Yoo IY,Oh JW,Cha HS,Koh EM,Kang ES

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Most immune reactions related to transfusion and transplantation are caused by IgM ABO antibodies. However, IgG also plays an important role in these reactions. Therefore, a method to measure antibodies, including IgG, is necessary. We investigated ABO antibody titers of healthy individuals using a column ag...

journal_title：Annals of laboratory medicine

authors： Park ES,Jo KI,Shin JW,Park R,Choi TY,Bang HI,Chai GR,Yun SG

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Although the incidence of tuberculosis (TB) is decreasing, cases of multidrug-resistant (MDR) TB and extensively drug-resistant (XDR) TB continue to increase. As conventional phenotype drug susceptibility testing (pDST) takes six to eight weeks, molecular assays are widely used to determine drug resistance. ...

journal_title：Annals of laboratory medicine

authors： Chang Y,Kim S,Kim Y,Ei PW,Hwang D,Lee J,Chang CL,Lee H

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Next-generation sequencing is increasingly used for taxonomic identification of pathogenic bacterial isolates. We evaluated the performance of a newly introduced whole genome-based bacterial identification system, TrueBac ID (ChunLab Inc., Seoul, Korea), using clinical isolates that were not identified by th...

journal_title：Annals of laboratory medicine

authors： Ha SM,Kim CK,Roh J,Byun JH,Yang SJ,Choi SB,Chun J,Yong D

更新日期：2019-11-01 00:00:00