Clonal Distribution of Clindamycin-Resistant Erythromycin-Susceptible (CRES) Streptococcus agalactiae in Korea Based on Whole Genome Sequences.

abstract：BACKGROUND:Real-time PCR is more sensitive than microscopic examination for detecting Pneumocystis jirovecii. We compared the performance of two assays for detecting P. jirovecii DNA: the RealStar Pneumocystis jirovecii PCR Kit 1.0 CE (Altona Diagnostics, Hamburg, Germany) and the AmpliSens Pneumocystis jirovecii (cari...

journal_title：Annals of laboratory medicine

authors： Huh HJ,Lim KR,Ki CS,Huh K,Shim HJ,Song DJ,Kim YJ,Chung DR,Lee NY

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:High-sensitivity cardiac troponin I (hs-cTnI) and the soluble isoform of suppression of tumorigenicity 2 (sST2) are useful prognostic biomarkers in acute coronary syndrome (ACS). The aim of this study was to test the short term prognostic value of sST2 compared with hs-cTnI in patients with chest pain. METH...

journal_title：Annals of laboratory medicine

authors： Marino R,Magrini L,Orsini F,Russo V,Cardelli P,Salerno G,Hur M,Di Somma S,GREAT NETWORK.

更新日期：2017-03-01 00:00:00

abstract：:Angiogenesis is important for the proliferation and survival of multiple myeloma (MM) cells. Bone marrow (BM) microvessel density (MVD) is a useful marker of angiogenesis and an increase in MVD can be used as a marker of poor prognosis in MM patients. We developed an automated image analyzer to assess MVD from images ...

journal_title：Annals of laboratory medicine

authors： Chung Y,Shin S,Shim H,Sohn JY,Lee DE,Lee H,Eom HS,Kim KG,Kong SY

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Neutrophil gelatinase-associated lipocalin (NGAL) is a useful biomarker for acute kidney injury (AKI) prediction. However, studies on whether using both plasma NGAL (PNGAL) and urine NGAL (UNGAL) can improve AKI prediction are limited. We investigated the best approach to predict AKI in high-risk patients wh...

journal_title：Annals of laboratory medicine

authors： Yi A,Lee CH,Yun YM,Kim H,Moon HW,Hur M

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Although the incidence of tuberculosis (TB) is decreasing, cases of multidrug-resistant (MDR) TB and extensively drug-resistant (XDR) TB continue to increase. As conventional phenotype drug susceptibility testing (pDST) takes six to eight weeks, molecular assays are widely used to determine drug resistance. ...

journal_title：Annals of laboratory medicine

authors： Chang Y,Kim S,Kim Y,Ei PW,Hwang D,Lee J,Chang CL,Lee H

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:ChromID Clostridium difficile agar (IDCd; bioMérieux SA, France) is a recently developed chromogenic medium for rapid and specific isolation of C. difficile. We compared the performance of IDCd with that of Clostridium difficile Selective Agar (CDSA). METHODS:A total of 530 fresh stool specimens were collec...

journal_title：Annals of laboratory medicine

authors： Shin BM,Lee EJ

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Differentiation of atypical pathogens is important for community-acquired pneumonia (CAP). In this study, we compared sputum and nasopharyngeal swabs (NPS) for use in detection of Mycoplasma pneumoniae (MP), Chlamydophila pneumoniae (CP), and Legionella pneumophila (LP), using Seeplex PneumoBacter ACE Detect...

journal_title：Annals of laboratory medicine

authors： Cho MC,Kim H,An D,Lee M,Noh SA,Kim MN,Chong YP,Woo JH

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia with a vancomycin minimum inhibitory concentration (MIC) of 2 µg/mL presents a high rate of therapeutic failure in response to vancomycin. In addition, polymorphism in accessory gene regulator (agr) is associated with vancomycin therapeutic effect...

journal_title：Annals of laboratory medicine

authors： Park MJ,Kim HS,Kim HS,Kim JS,Song W,Kim MY,Lee YK,Kang HJ

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:In the past, ABO incompatibility was an absolute contraindication for solid organ transplantation. However, multiple recent trials have suggested strategies for overcoming the reactions between graft antigens and recipient antibodies that cause graft rejection. In this study, we determined the usefulness of ...

journal_title：Annals of laboratory medicine

authors： Yoo S,Lee EY,Huh KH,Kim MS,Kim YS,Kim HO

更新日期：2012-07-01 00:00:00

abstract：:Procalcitonin (PCT) is used as a biomarker for the diagnosis of sepsis, severe sepsis and septic shock. At the same time, PCT has also been used to guide antibiotic therapy. This review outlines the main indications for PCT measurement and points out possible pitfalls. The classic indications for PCT measurement are: ...

journal_title：Annals of laboratory medicine

authors： Meisner M

更新日期：2014-07-01 00:00:00

abstract：:Coagulase-negative staphylococci (CoNS) are reported to be the leading cause of nosocomial bloodstream infections. Staphylococcus pettenkoferi is a novel member of CoNS that was first isolated from the human blood and bursitis wound in 2002. We have reported cases of 6 S. pettenkoferi strains isolated from blood speci...

journal_title：Annals of laboratory medicine

authors： Park S,Chung HS,Lee M

更新日期：2015-03-01 00:00:00

abstract：Background:HLA-DQ typing in deceased donors is not mandatory in Korea. Therefore, when patients develop DQ antibodies after kidney transplantation (KT) from deceased donor, it is impossible to determine whether they are donor-specific antibodies (DSA). We developed DQ prediction programs for the HLA gene and evaluated ...

journal_title：Annals of laboratory medicine

authors： Kim SK,Yang JJ,Hwang SH,Sung H,Shin S,Ko SY,Oh HB

更新日期：2021-03-01 00:00:00

abstract：BACKGROUND:Narcolepsy is a neurologic disorder characterized by excessive daytime sleepiness, symptoms of abnormal rapid eye movement (REM) sleep, and a strong association with HLA-DRB1*1501, -DQA1*0102, and -DQB1*0602. Here, we investigated the clinico-physical characteristics of Korean patients with narcolepsy, their...

journal_title：Annals of laboratory medicine

authors： Woo HI,Joo EY,Hong SB,Lee KW,Kang ES

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Clarithromycin, amoxicillin, metronidazole, tetracycline, and levofloxacin have been commonly used for the eradication of Helicobacter pylori. We compared the change in antibiotic resistance of H. pylori strains during two separate periods and investigated the effect of antibiotic resistance on H. pylori era...

journal_title：Annals of laboratory medicine

authors： An B,Moon BS,Kim H,Lim HC,Lee YC,Lee G,Kim SH,Park M,Kim JB

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Most immune reactions related to transfusion and transplantation are caused by IgM ABO antibodies. However, IgG also plays an important role in these reactions. Therefore, a method to measure antibodies, including IgG, is necessary. We investigated ABO antibody titers of healthy individuals using a column ag...

journal_title：Annals of laboratory medicine

authors： Park ES,Jo KI,Shin JW,Park R,Choi TY,Bang HI,Chai GR,Yun SG

更新日期：2014-05-01 00:00:00

abstract：:[This corrects the article on p. 439 in vol. 40.]. ...

journal_title：Annals of laboratory medicine

authors： Sung H,Roh KH,Hong KH,Seong MW,Ryoo N,Kim HS,Lee J,Kim SY,Ryu SW,Kim MN,Han MG,Lee SW,Lee H,Yoo CK

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:We evaluated the performance of four commercial nucleic acid amplification tests (NAATs: Xpert C. difficile, BD MAX Cdiff, IMDx C. difficile for Abbott m2000, and Illumigene C. difficile) for direct and rapid detection of Clostridium difficile toxin genes. METHODS:We compared four NAATs on the same set of 3...

journal_title：Annals of laboratory medicine

authors： Shin BM,Yoo SM,Shin WC

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate a newly developed PCR-based reverse blot hybridization assay (PCR-REBA), REBA Sepsis-ID (M&D, Wonju, Korea), to rapidly detect the presence of bacteremia and antimicrobial resistance gene in blood culture samples. METHODS:One thousand four hundred consecutive blood cult...

journal_title：Annals of laboratory medicine

authors： Park SD,Lee G,Wang HY,Park M,Kim S,Kim H,Kim J,Kim YK,Kim HY,Lee H,Uh Y,Kim JB

更新日期：2014-11-01 00:00:00

abstract：:Guidelines recommend that clinical laboratories perform phenotypic tests (nitrocefin-based test and penicillin 10-U [P10] or 1-U [P1] zone edge tests) to detect penicillinase in Staphylococcus aureus isolates. This study aimed to assess the prevalence of blaZ encoding penicillinase and perform various phenotypic tests...

journal_title：Annals of laboratory medicine

authors： Takayama Y,Tanaka T,Oikawa K,Fukano N,Goto M,Takahashi T

更新日期：2018-03-01 00:00:00

abstract：:Myocardial infarction (MI) is the leading cause of death in the developed world. Biomarkers have an essential role in diagnosis, risk stratification, guiding management and clinical decision making in the setting of patients presenting with signs and symptoms of MI. Cardiac troponin (cTn) rose to prominence during the...

journal_title：Annals of laboratory medicine

authors： Christenson E,Christenson RH

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Mutations in calreticulin (CALR) have been reported to be key markers in the molecular diagnosis of myeloid proliferative neoplasms. In most previous reports, CALR mutations were analyzed by using Sanger sequencing. Here, we report a new, rapid, and convenient system for screening CALR mutations without sequ...

journal_title：Annals of laboratory medicine

authors： Jeong JH,Lee HT,Seo JY,Seo YH,Kim KH,Kim MJ,Lee JH,Park J,Hong JS,Park PW,Ahn JY

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare inherited disorder characterized by infantile-onset macrocephaly, slow neurologic deterioration, and seizures. Mutations in the causative gene, MLC1, are found in approximately 75% of patients and are inherited in an autosomal recessi...

journal_title：Annals of laboratory medicine

authors： Choi SA,Kim SY,Yoon J,Choi J,Park SS,Seong MW,Kim H,Hwang H,Choi JE,Chae JH,Kim KJ,Kim S,Lee YJ,Nam SO,Lim BC

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:The level of Galectin-3 (Gal-3) protein purportedly reflects an ongoing cardiac fibrotic process and has been associated with ventricular remodeling, which is instrumental in the development of heart failure with preserved ejection fraction (HFpEF) syndrome. The aim of this study was to investigate the poten...

journal_title：Annals of laboratory medicine

authors： Ansari U,Behnes M,Hoffmann J,Natale M,Fastner C,El-Battrawy I,Rusnak J,Kim SH,Lang S,Hoffmann U,Bertsch T,Borggrefe M,Akin I

更新日期：2018-07-01 00:00:00

abstract：:Changes in microparticles (MP) from red blood cell (RBC) concentrates in the context of irradiation have not been investigated. The aim of this study was to evaluate how irradiation affects the number of MPs within transfusion components. Twenty RBC concentrates, within 14 days after donation, were exposed to gamma ra...

journal_title：Annals of laboratory medicine

authors： Cho CH,Yun SG,Koh YE,Lim CS

更新日期：2016-07-01 00:00:00

abstract：:Metachromatic leukodystrophy (MLD) is an autosomal recessive disease caused by a deficiency in arylsulfatase A (ARSA). However, decreased ARSA activity is also observed in pseudodeficiency (PD). To distinguish between MLD and PD, we performed gene mutation and sulfatide analyses by using dried blood spots (DBSs) from ...

journal_title：Annals of laboratory medicine

authors： Han M,Jun SH,Lee YJ,Eun BL,Lee SJ,Seong MW,Park SS,Song SH,Park HD,Song J

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Clopidogrel is one of the most commonly used anti-platelet agents in cardiovascular diseases. We analyzed the relationship between the platelet function analyzer (PFA)-200 P2Y (INNOVANCE PFA-200 System, Siemens Healthcare, Germany) results and occurrence of major adverse cardiac events (MACEs) in Korean pati...

journal_title：Annals of laboratory medicine

authors： Lim HH,Li S,An GD,Woo KS,Kim KH,Kim JM,Kim MH,Han JY

更新日期：2018-09-01 00:00:00

abstract：:Candidemia due to uncommon Candida spp. appears to be increasing in incidence. C. dubliniensis has been increasingly recovered from individuals not infected with HIV. Identification of C. dubliniensis can be problematic in routine clinical practice due to its phenotypic resemblance to C. albicans. We report the first ...

journal_title：Annals of laboratory medicine

authors： Yu N,Kim HR,Lee MK

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Many laboratories use 4 delta check methods: delta difference, delta percent change, rate difference, and rate percent change. However, guidelines regarding decision criteria for selecting delta check methods have not yet been provided. We present new decision criteria for selecting delta check methods for e...

journal_title：Annals of laboratory medicine

authors： Park SH,Kim SY,Lee W,Chun S,Min WK

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The Automated Fluorescent Immunoassay System (AFIAS) rotavirus assay (Boditech Med Inc., Chuncheon, Korea) is a new rapid antigen test for rotavirus detection. We evaluated the performance of this assay for detecting rotaviruses and their specific genotypes in clinical stool samples. METHODS:AFIAS rotavirus...

journal_title：Annals of laboratory medicine

authors： Kim JS,Lee SK,Ko DH,Hyun J,Kim HS

更新日期：2019-01-01 00:00:00

abstract：:In 2015, the American College of Medical Genetics and Genomics (ACMG), together with the Association for Molecular Pathology (AMP), published the latest guidelines for the interpretation of sequence variants, which have been widely adopted into clinical practice. Despite these standardized efforts, the degrees of subj...

journal_title：Annals of laboratory medicine

authors： Kim YE,Ki CS,Jang MA

更新日期：2019-09-01 00:00:00