Wine Chemical Composition and Radical Scavenging Activity of Some Cabernet Franc Clones.

abstract：:Hepatocellular carcinoma (HCC) represents the third cause of cancer-related death. Because HCC is multi-centric with time, excluding the few transplanted patients, sooner or later it becomes untreatable with loco-regional therapies and, until some years ago, it was not responsive to systemic therapies. In 2005 a rando...

journal_title：Current pharmaceutical biotechnology

authors： Livraghi T,Ceriani R,Palmisano A,Pedicini V,Pich MG,Tommasini MA,Torzilli G

更新日期：2011-02-01 00:00:00

abstract：:The purpose of this review article is to describe the history of photodynamic therapy (PDT), its current medical applications, the mechanism of action, contraindications of the method, and different types of photosensitizers used. The second part of the article deals with applications for gastrointestinal diseases. Th...

journal_title：Current pharmaceutical biotechnology

authors： Wiedmann MW,Caca K

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Despite the extended laboratory and clinical study of sepsis, its diagnosis remains a clinical challenge. The initiation of sepsis activates many different biochemical and immunological pathways being expressed by alterations of various molecules in human tissues. The detection and measurement of the concent...

journal_title：Current pharmaceutical biotechnology

authors： Giannakopoulos K,Hoffmann U,Ansari U,Bertsch T,Borggrefe M,Akin I,Behnes M

更新日期：2017-01-01 00:00:00

abstract：:Tissue engineering is a rapidly developing field applying the disciplines of cell biology, developmental biology, molecular biology and biomimetic engineering to regenerate new tissues for replacement therapies in clinical contexts. To aid in the elicitation and reiteration of the processes of morphogenesis of tissues...

journal_title：Current pharmaceutical biotechnology

authors： Ripamonti U,Tasker JR

更新日期：2000-07-01 00:00:00

abstract：:A variety of methods including penetrating enhancers, enzyme inhibitors, as well as cargo mediated drug delivery have been explored to improve the intolerance of parenteral administrated insulin, but little success has been achieved so far. Under this background, cell penetrating peptides (CPPs), with their ability to...

journal_title：Current pharmaceutical biotechnology

authors： Liu E,Sheng J,Ye J,Wang Y,Gong J,Yang VC,Wang J,He H

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Nitrate and nitrite can get into the body through the consumption of contaminated water either directly or indirectly. The accumulation of these compounds in the body, in the long run, leads to health problems, for example, digestive disorders, cancers, and even death threats in children. The aim of this rev...

journal_title：Current pharmaceutical biotechnology

authors： Marhamati M,Afshari A,Kiani B,Jannat B,Hashemi M

更新日期：2020-12-03 00:00:00

abstract：:Fc-based therapeutics including therapeutic full-size monoclonal antibodies (mAbs) and Fcfusion proteins represent fastest-growing market in biopharmaceutical industrial. However, one major challenge during development of Fc-based therapeutics is how to maintain their efficacy in clinic use. Many factors may lead to f...

journal_title：Current pharmaceutical biotechnology

authors： Chen X,Zeng F,Huang T,Cheng L,Liu H,Gong R

更新日期：2016-01-01 00:00:00

abstract：:In this review, the compartments of the vasculature will be discussed with respect to their potential contribution to the build-up of a differentiated and functionally meaningful vessel system. Chronic ischemia of muscle tissue results in microvessel rarification, which represents a potential therapeutic target, given...

journal_title：Current pharmaceutical biotechnology

authors： Kupatt C

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Rheumatoid arthritis (RA) is a common connective tissue disease, characteristic of chronic and invasive synovitis in single or multiple joints and vasculitis. RA is a heterogeneous disease with unclear pathogenesis. Therefore, exploring the etiology and pathogenesis of the disease is essential for identifyin...

journal_title：Current pharmaceutical biotechnology

authors： Liu J,Wang X,Wang S,Liu F

更新日期：2020-10-01 00:00:00

abstract：:Mammalian cells are involved in a range of biotechnological applications and more recently have been increasingly exploited in regenerative medicine. Critical to successful applications involving mammalian cells are their long-term storage and transport, for which cryopreservation in liquid nitrogen is the most freque...

journal_title：Current pharmaceutical biotechnology

authors： Chau DY,Dennis AR,Lin H,Zeitler JA,Tunnacliffe A

更新日期：2015-01-01 00:00:00

abstract：:Data obtained through high-throughput technologies have gradually revealed that a unique stratified epithelial architecture of human skin along with the antioxidant-response pathways provided vital defensive mechanisms against UV radiation. However, it is noteworthy that skin is a major target for toxic insult by UV r...

journal_title：Current pharmaceutical biotechnology

authors： Farooqi AA,Li RN,Huang HW,Ismail M,Yuan SS,Wang HM,Liu JR,Tang JY,Chang HW

更新日期：2015-01-01 00:00:00

abstract：:Bone grafts are widely used for augmentation procedures in oral and maxillofacial surgery, with autogenous bone being the gold standard. Recently, the focus of research has shifted towards synthetic bone substitutes, as no second surgery is needed and large quantities of graft can easily be provided. Within the broad ...

journal_title：Current pharmaceutical biotechnology

authors： Gotz W,Papageorgiou SN

更新日期：2017-01-01 00:00:00

abstract：:The bioethical and juridical debate on the status of frozen embryos sometimes adds new issues arising from new scientific evidence or by accidental occurrences that bring to the attention of the scientific community the need for new practical solutions. Within this scenario, there have been, in recent years, episodes ...

journal_title：Current pharmaceutical biotechnology

authors： Busardò FP,Vergallo GM,Turillazzi E,Bolino G,Vullo A,Frati P

更新日期：2016-01-01 00:00:00

abstract：:Progress in many therapies, in particular in the therapies based on peptides, proteins and nucleic acids used as bioactive compounds, strongly depends on development of appropriate carriers which would be suitable for controlled delivery of the intact abovementioned compounds to required tissues, cells and intracellul...

journal_title：Current pharmaceutical biotechnology

authors： Slomkowski S,Gosecki M

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Recently, spinel structures (AB2O4) nanoparticles (NPs) having binary and ternary mixtures of metal oxides were established as promising redox catalysts. Due to the presence of two mixed valence metal cations transport of electrons takes place easily between multiple transition-metal cations with relatively ...

journal_title：Current pharmaceutical biotechnology

authors： Patel AR,Sereda G,Banerjee S

更新日期：2020-11-17 00:00:00

abstract：:Herpes simplex virus (HSV) is a well-known vector that is often used for gene therapy to treat cancers. The most attractive feature of HSV is its ability to destroy tumors through a distinctive oncolytic mechanism where the virus can destroy cancer cells via cell lysis, a killing function that no anti-cancer drugs can...

journal_title：Current pharmaceutical biotechnology

authors： Wong J,Lee C,Zhang K,Rennie PS,Jia W

更新日期：2012-07-01 00:00:00

abstract：:Carbon nanotubes are nano sized cylindrical chicken wire like structures made of carbon atoms. Carbon nanotubes have applications in electronics, energy storage, electromagnetic devices, environmental remediation and in medicine as well. The biomedical applications of carbon nanotubes can be owed to features like low ...

journal_title：Current pharmaceutical biotechnology

authors： Wani TU,Mohi-Ud-Din R,Wani TA,Hassan R,Itoo AM,Sheikh FA,Khan NA,Pottoo FH

更新日期：2020-11-10 00:00:00

abstract：:Xylitol is an important polyalcohol suitable for use in odontological, medical and pharmaceutical products and as an additive in food. The first studies on the efficacy of xylitol in the control and treatment of infections started in the late 1970s and it is still applied for this purpose, with safety and very little ...

journal_title：Current pharmaceutical biotechnology

authors： Ferreira AS,Silva-Paes-Leme AF,Raposo NR,da Silva SS

更新日期：2015-01-01 00:00:00

abstract：:The innate immune system protects against infectious microbes by the recognition of pathogen- associated molecular patterns, which serve to detect pathogens on the host cell surface or in endosomes by pattern recognition receptors such as Toll-like receptors, nucleotide-binding oligomerization domain-containing protei...

journal_title：Current pharmaceutical biotechnology

authors： Fischer S

更新日期：2018-01-01 00:00:00

abstract：:As sessile and filter-feeding metazoans, marine sponges represent an ecologically important and highly diverse component of marine benthic communities throughout the world. It has been suggested that marine sponges are hosts to many microorganisms which can constitute up to 40-60% of its biomass. Recently, sponges hav...

journal_title：Current pharmaceutical biotechnology

authors： Santos-Gandelman JF,Giambiagi-deMarval M,Oelemann WM,Laport MS

更新日期：2014-01-01 00:00:00

abstract：:Silkworm pupae protein is a good source of high quality protein. The hydrolyzates of silkworm pupae protein catalyzed by neutrase, pepsin, acidic protease (Asperqiius usamii NO. 537), flavourzyme, alcalase, and trypsin with inhibitory activity on angiotensin I-converting enzyme (ACE) were identified by HPLC. The hydro...

journal_title：Current pharmaceutical biotechnology

authors： Wang W,Shen S,Chen Q,Tanga B,He G,Ruan H,Das UN

更新日期：2008-08-01 00:00:00

abstract：:Long-term increase of blood pressure represents one of the most important risk factors triggering many cardiovascular diseases, and via counter-regulatory mechanisms it is itself modulated by them. Adequate perfusion of the respective areas with nutrients requires appropriate production of vasodilatory and vasoconstri...

journal_title：Current pharmaceutical biotechnology

authors： Kristek F

更新日期：2011-09-01 00:00:00

abstract：:The number of diseases found to be associated with defects of the mitochondrial genome has grown significantly over the last decade. Despite major advances in understanding mtDNA defects at the genetic and biochemical level, there is no satisfactory treatment for the vast majority of patients available. This is largel...

journal_title：Current pharmaceutical biotechnology

authors： Weissig V,Torchilin VP

更新日期：2000-12-01 00:00:00

abstract：:Increasing evidence shows that the interaction between neoplastic cells and the surrounding stroma is a critical factor in solid tumor growth. The tumor stroma is made up of diverse cellular populations including macrophages, lymphocytes, vascular cells, and carcinoma-associated fibroblasts. The complex interactions b...

journal_title：Current pharmaceutical biotechnology

authors： Anton K,Glod J

更新日期：2009-02-01 00:00:00

abstract：:This review describes microbial transformation studies of natural drugs, its importance in correlating them with the corresponding metabolism (biotransformation) in animal system and in the structural modification of complex drug molecules, which are difficult to obtain synthetically. Emphasis is laid on the potential...

journal_title：Current pharmaceutical biotechnology

authors： Venisetty RK,Ciddi V

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:Frequent administrations for DPPIV-resistant GLP-1 analogs are necessary to maintain the blood concentrations due to the short half-life of less than 5 minutes. However, most delivery systems that possess the ability of sustainable release of GLP-1 have drawbacks such as low yield, high cost and undesirable s...

journal_title：Current pharmaceutical biotechnology

authors： Fan L,Fan Y,Fan H,Huang K

更新日期：2020-01-01 00:00:00

abstract：:Polyphenols are a widely distributed group of natural products found in fruits, vegetables, nuts, seeds, stems and flowers. Such compounds, especially dietary flavonoids and tannins, have been shown to exert antioxidant, antiinflammatory, anti-cancer and antibacterial effects and may have beneficial effects on human h...

journal_title：Current pharmaceutical biotechnology

authors： Coppo E,Marchese A

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Nanotechnology involves the synthesis of materials that are in nanometre sizes (1 to 100 nm). Nanotechnology has appeared as a new area of fundamental science and is getting worldwide consideration due to its extensive applications. They have exceptional physicochemical properties due to their unique size, s...

journal_title：Current pharmaceutical biotechnology

authors： Roy A

更新日期：2020-10-27 00:00:00

abstract：:Spirulina, a filamentous cyanobacterium, possesses diverse biological activities and nutritional significance due to high concentration of natural nutrients, having bio-modulatory and immuno-modulatory functions. Different Spirulina preparations influence immune system viz. increase phagocytic activity of macrophages,...

journal_title：Current pharmaceutical biotechnology

authors： Khan Z,Bhadouria P,Bisen PS

更新日期：2005-10-01 00:00:00

abstract：:Recent technological advances in NMR methods and instrumentation are having a significant impact in structural biology. These innovations are also impacting pharmaceutical biotechnology as it is now possible to use NMR spectroscopy to rapidly characterize a growing number of prospective protein drugs and protein drug ...

journal_title：Current pharmaceutical biotechnology

authors： Wishart D

更新日期：2005-04-01 00:00:00