Complete response in 5 out of 38 patients with advanced hepatocellular carcinoma treated with stem cell differentiation stage factors: case reports from a single centre.

abstract：:Lactobacilli are common microorganisms in diverse vegetables and meat products and several of these are also indigenous inhabitants in the gastro-intestinal (GI) tract of humans and animals where they are believed to have health promoting effects on the host. One of the highly appreciated probiotic effects is their ab...

journal_title：Current pharmaceutical biotechnology

authors： Diep DB,Mathiesen G,Eijsink VG,Nes IF

更新日期：2009-01-01 00:00:00

abstract：:The design and development of novel biological drugs are among the most exciting new areas of biotechnology which are gaining the attention of scientists. In the last few decades several fabrication processes have been proposed and developed for the production of recombinant growth factors. However, traditional produc...

journal_title：Current pharmaceutical biotechnology

authors： Laura W,Pablo L,Arantxa A,Isabel B,Alberto R,Silvia J,Noelia C,de Francisco Ana,Raquel C,Gorka O

更新日期：2016-01-01 00:00:00

abstract：:Platelet concentrates for surgical use are innovative tools of regenerative medicine, and were widely tested in oral and maxillofacial surgery. Unfortunately, the literature on the topic is contradictory and the published data are difficult to sort and interpret. In bone graft, implant and reconstructive surgery, the ...

journal_title：Current pharmaceutical biotechnology

authors： Simonpieri A,Del Corso M,Vervelle A,Jimbo R,Inchingolo F,Sammartino G,Dohan Ehrenfest DM

更新日期：2012-06-01 00:00:00

abstract：:SARS-CoV 2 is a novel virus strain of Coronavirus, reported in China in late December 2019. Its highly contagious nature in humans has prompted WHO to designate the ongoing pandemic as a Public Health Emergency of International Concern. At this moment, there is no specific treatment and the therapeutic strategies to d...

journal_title：Current pharmaceutical biotechnology

authors： Adithya J,Nair B,Aishwarya S,Nath LR

更新日期：2020-08-06 00:00:00

abstract：:Schizophrenia is a severe mental disorder, characterized by a complex symptomatology and a chronic relapsing course, leading to a more or less intensive residual syndrome. The disorder has strong consequences on social functioning and on the patients' quality of life and is associated with a huge economical burden for...

journal_title：Current pharmaceutical biotechnology

authors： Moller HJ

更新日期：2012-06-01 00:00:00

abstract：:Beyond their originally sole mechanical function, current drug-eluting stents (DES) implement the concept of local drug delivery for the re-opening of stenotic arterial vessels, and for prevention of in-stent restenosis as one of the major limitations of conventional bare metal stents (BMS). Current DES consist of a p...

journal_title：Current pharmaceutical biotechnology

authors： Sternberg K,Grabow N,Petersen S,Weitschies W,Harder C,Ince H,Kroemer HK,Schmitz KP

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:We sought to evaluate the safety of imipenem and meropenem in the treatment of infections in neurosurgical patients. METHODS:An observational retrospective study was conducted of consecutive cases treated with imipenem from Sept. 2007 to Sept. 2009 and meropenem within 1 year from Sept. 2008 in Beijing Tiant...

journal_title：Current pharmaceutical biotechnology

authors： Wu Y,Chen K,Shi Z,Wang Q

更新日期：2014-01-01 00:00:00

abstract：:In this review, the compartments of the vasculature will be discussed with respect to their potential contribution to the build-up of a differentiated and functionally meaningful vessel system. Chronic ischemia of muscle tissue results in microvessel rarification, which represents a potential therapeutic target, given...

journal_title：Current pharmaceutical biotechnology

authors： Kupatt C

更新日期：2007-02-01 00:00:00

abstract：: ...

journal_title：Current pharmaceutical biotechnology

authors： Giaginis C

更新日期：2018-01-01 00:00:00

abstract：:Active or passive immunotherapy is expected to slow or stop the pathological process of Alzheimer's disease (AD). Immunotherapy for AD has demonstrated that targeting beta-amyloid (Aβ) or tau protein with vaccines or antibodies can reduce AD pathologies. Active anti-Aβ immunization for AD includes using AN1792 and sec...

journal_title：Current pharmaceutical biotechnology

authors： Yang C,Xiao S

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Fractalkine (FKN) in its free and membrane bound-forms and its receptor CX3CR1are reported to have an atherosclerotic effect. The relationship of Single Nucleotide Polymorphisms (SNPs) in FKN and CX3CR1genes with the Coronary Artery Disease (CAD) risk showed conflicting results in different populations. The ...

journal_title：Current pharmaceutical biotechnology

authors： Hassan DS,Hashad IM,Abdel Rahman MF,Abdel-Maksoud SM

更新日期：2018-01-01 00:00:00

abstract：:Interstitial lung disease (ILD) is one of the most common complications of polymyositis (PM) and dermatomyositis (DM). It is always progressive and does not respond to conventional immunosuppressive agent treatment. Biologics are commonly used in treatment of rheumatic diseases. They are also used in polymyositis and ...

journal_title：Current pharmaceutical biotechnology

authors： Sun Y,He Y,Liu Y,Shi G

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:To date, an increasing number of pet owners, especially in the USA, are using cannabis-derived products containing generally delta 9-tetrahydrocannabinol (THC) and cannabidiol (CBD) to help their animals' health. Unfortunately, studies on the clinical use of cannabinoids in veterinary medicine are still limi...

journal_title：Current pharmaceutical biotechnology

authors： Rotolo MC,Graziano S,Pellegrini M,Corlazzoli D,Antinori L,Porcarelli L,Pichini S

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Three clones of Cabernet Franc (Nos. 02, 010 and 012) were selected in the last phase of clonal selection in Serbia. Wines made from each clone were assessed for quality parameters and taste during five consecutive vintages (2008-2012) and compared to the standard. The wine quality was determined based on th...

journal_title：Current pharmaceutical biotechnology

authors： Popovic-Djordjevic J,Pejin B,Dramicanin A,Jovic S,Vujovic D,Zunic D,Ristic R

更新日期：2017-01-01 00:00:00

abstract：:Midkine is a heparin-binding growth factor that promotes cell growth, survival, and migration. Externally added midkine prevents ventricular remodeling and improves long-term survival after myocardial infarction in the mouse. Preclinical testing of this protein is in progress. Externally added pleiotrophin, a member o...

journal_title：Current pharmaceutical biotechnology

authors： Murasugi A

更新日期：2013-01-01 00:00:00

abstract：:3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (also known as statins) are drugs active in the blockade of cholesterol synthesis and thus lowering cholesterol serum levels. Since their discovery, experimental evidence showed that statins strongly reduced atherogenesis and the risk of acute ischem...

journal_title：Current pharmaceutical biotechnology

authors： Montecucco F,Quercioli A,Mirabelli-Badenier M,Viviani GL,Mach F

更新日期：2012-01-01 00:00:00

abstract：:Proliposomes are phospholipid based drug delivery systems that are finding important applications in the field of pharmaceutics. Proliposomes have been extensively studied as a potential carrier for oral delivery of drugs with poor bioavailability, but the mechanism of absorption and cellular uptake pathways has not y...

journal_title：Current pharmaceutical biotechnology

authors： Nekkanti V,Venkatesan N,Betageri GV

更新日期：2015-01-01 00:00:00

abstract：:Platelet-rich plasma (PRP) is widely used to promote tissue repair and accelerate osteogenesis, but there is no agreement about its mechanism of action. We characterized the modulatory effect of PRP on the in vitro osteoblast model SaOS-2, by using cell motility/chemoattraction and osteogenesis/mineralization assays, ...

journal_title：Current pharmaceutical biotechnology

authors： Martinotti S,Mazzucco L,Balbo V,Patrone M,Mozzati M,Ranzato E,Burlando B

更新日期：2014-01-01 00:00:00

abstract：:Foods and nutrients play a vital role in normal functioning of the body. They are helpful in maintaining the health of the individual and in reducing the risk of various diseases. Worldwide acceptance of this fact formed a recognition link between "nutrition" and "health" and the concept of "nutraceuticals" was evolve...

journal_title：Current pharmaceutical biotechnology

authors： Ramaa CS,Shirode AR,Mundada AS,Kadam VJ

更新日期：2006-02-01 00:00:00

abstract：AIMS:Globally Scientists are working to find more efficient antimicrobial drugs to treat microbial infections and kill drug-resistant bacteria. BACKGROUND:Despite the availability of numerous antimicrobial drugs bacterial infections still poses a serious threat to global health. Due to a constant decline in the effect...

journal_title：Current pharmaceutical biotechnology

authors： Khan K,Qureshi MA,Azam A,Moinuddin,Musarrat J,Javed S

更新日期：2021-01-18 00:00:00

abstract：:The blood-brain barrier (BBB), which impedes drug penetration into the central nervous system, is composed of specific structures formed by brain capillary endothelial cells and sheathed by astrocytic end-feet through basement membrane. Many brain drug delivery strategies have focused on adsorptive-mediated transcytos...

journal_title：Current pharmaceutical biotechnology

authors： Lu W

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:The goals of this study were to observe how luteolin protects endothelial cells (ECs) from injury stimulated by Angiotensin II (Ang II), investigate the role of vascular endothelial dysfunction in vascular smooth muscle cell proliferation and migration in vitro and investigate its primary mechanism of action....

journal_title：Current pharmaceutical biotechnology

authors： Ding H,Li D,Zhang Y,Zhang T,Zhu H,Xu T,Luo Y,Wang C

更新日期：2014-01-01 00:00:00

abstract：:Momordica balsamina, African pumpkin (Cucurbitaceae), is a tendril-bearing, wild climber containing wide spectrum of medicinal and nutritional values and has been used as a traditional folk medicine in many countries. The leaves, fruits, seeds, and bark of the plant contains resins, alkaloids, flavonoids, glycosides, ...

journal_title：Current pharmaceutical biotechnology

authors： Thakur GS,Bag M,Sanodiya BS,Bhadouriya P,Debnath M,Prasad GB,Bisen PS

更新日期：2009-11-01 00:00:00

abstract：:The innate immune system protects against infectious microbes by the recognition of pathogen- associated molecular patterns, which serve to detect pathogens on the host cell surface or in endosomes by pattern recognition receptors such as Toll-like receptors, nucleotide-binding oligomerization domain-containing protei...

journal_title：Current pharmaceutical biotechnology

authors： Fischer S

更新日期：2018-01-01 00:00:00

abstract：:Tumor cells show metabolic features distinctive from normal tissues, with characteristically enhanced aerobic glycolysis, glutaminolysis and lipid synthesis. Peroxisome proliferator activated receptor α (PPAR α) is activated by nutrients (fatty acids and their derivatives) and influences these metabolic pathways actin...

journal_title：Current pharmaceutical biotechnology

authors： Grabacka M,Pierzchalska M,Reiss K

更新日期：2013-01-01 00:00:00

abstract：:MicroRNAs are small non-coding RNA molecules which do not code for proteins, but control the expression of a significant proportion of the genome. The microRNA expression differences of normal and malignant tissue, as well as the differences in various tumor entities qualify this RNA species as biomarker for cancer pa...

journal_title：Current pharmaceutical biotechnology

authors： Ellinger J,Muller SC

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Pentoxifylline (PTX) is a drug commonly used in the treatment of intermittent claudication. However, numerous research groups report that PTX also may potentially be used in the anticancer therapy following one of the main trends in the nowadays medicine - combined anticancer therapy. SCOPE OF REVIEW:The re...

journal_title：Current pharmaceutical biotechnology

authors： Golunski G,Woziwodzka A,Piosik J

更新日期：2018-01-01 00:00:00

abstract：:As an important nano-material, nano-copper oxide particles (CuO-ENPs) harbor a vast range of characteristics, including electronic correlation effect, thermal stability, catalytic activity, sterilization and other properties. At present, the mechanism of ecotoxicological effects of CuO-ENPs is not yet clear, and has b...

journal_title：Current pharmaceutical biotechnology

authors： Li T,Hu H,Yang C,Zhang B,Ma L

更新日期：2020-12-28 00:00:00

abstract：:Silkworm pupae protein is a good source of high quality protein. The hydrolyzates of silkworm pupae protein catalyzed by neutrase, pepsin, acidic protease (Asperqiius usamii NO. 537), flavourzyme, alcalase, and trypsin with inhibitory activity on angiotensin I-converting enzyme (ACE) were identified by HPLC. The hydro...

journal_title：Current pharmaceutical biotechnology

authors： Wang W,Shen S,Chen Q,Tanga B,He G,Ruan H,Das UN

更新日期：2008-08-01 00:00:00

abstract：:Autonomic neural functions are important to regulate vital functions in the living body. There are different methods to evaluate indirectly and directly autonomic, sympathetic and parasympathetic, neural functions of human body. Among various methods, microneurography is a technique to evaluate directly sympathetic ne...

journal_title：Current pharmaceutical biotechnology

authors： Mano T

更新日期：2005-08-01 00:00:00