听力与言语-语言病理学

行为科学

医学伦理学

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  • Pharmaceutical importance of some promising plant species with special reference to the isolation and extraction of bioactive compounds: A review.

    abstract:BACKGROUND:Active principles from natural sources, in the form of extracts and natural compounds, provide an infinite number of bioactive compounds with consummate disposal of chemical diversity. These compounds and active principles are of utmost importance in the discovery of drugs of biological origin particularly, ...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201022666210122125854

    authors: Das G,Patra JK,Kang SS,Shin HS

    更新日期:2021-01-22 00:00:00

  • Biopharmaceutical and pharmacokinetic activities of oxymatrine determined by a sensitive UHPLC-MS/MS method.

    abstract:BACKGROUND:Oxymatrine is one of the most promising alkaloids from Sophora flavescens for its excellent pharmacological effects. OBJECTIVE:The aim of this research is to assess the biopharmaceutical and pharmacokinetic activities of oxymatrine, and clarify its mechanisms of absorption and metabolism. METHODS:The biolo...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201022666210118160529

    authors: Wang HQ,Chen FH,Wang L,Chi LQ,Wang GH

    更新日期:2021-01-18 00:00:00

  • Ampicillin-augmented silver nanoparticles for synergistic antimicrobial response: A promising therapeutic approach.

    abstract:AIMS:Globally Scientists are working to find more efficient antimicrobial drugs to treat microbial infections and kill drug-resistant bacteria. BACKGROUND:Despite the availability of numerous antimicrobial drugs bacterial infections still poses a serious threat to global health. Due to a constant decline in the effect...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201022666210119101522

    authors: Khan K,Qureshi MA,Azam A,Moinuddin,Musarrat J,Javed S

    更新日期:2021-01-18 00:00:00

  • Novel Therapeutic Approaches and Targets for Treatment of Vulvar Lichen Sclerosus.

    abstract:BACKGROUND:Vulvar Lichen Sclerosus (VLS) is a chronic inflammatory disease with a huge impact on a person's quality of life. A correct therapy is required for relieving symptoms, reversing signs and preventing further anatomical changes. OBJECTIVE:The main objective of the present paper is to provide suggestions for t...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666200516154310

    authors: Borghi A,Corazza M

    更新日期:2021-01-01 00:00:00

  • Pomelo Peel Volatile Oil Alleviates Neuroinflammation on Focal Cerebral Ischemia Reperfusion Injury Rats via Inhibiting TLR4/NF-κB Signaling Pathway.

    abstract:BACKGROUND:Restoration of blood flow during ischemic stroke leads to cerebral ischemia reperfusion injury (CIRI) by activating neuroinflammatory cascades. Pomelo peel volatile oil (PPVO) extracted from Citrus maxima (Burm.) from the genus Rutaceae, comprises some anti-inflammatory ingredients, such as limonene and β-my...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201022666201231114403

    authors: Tian XY,Xie L,Wang WY,Zou XS,Zhao GY,Chen MH

    更新日期:2020-12-30 00:00:00

  • A Study on Ecotoxicological Effects of Nano-copper Oxide Particles to Portunus Trituberculatus.

    abstract::As an important nano-material, nano-copper oxide particles (CuO-ENPs) harbor a vast range of characteristics, including electronic correlation effect, thermal stability, catalytic activity, sterilization and other properties. At present, the mechanism of ecotoxicological effects of CuO-ENPs is not yet clear, and has b...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666201229111251

    authors: Li T,Hu H,Yang C,Zhang B,Ma L

    更新日期:2020-12-28 00:00:00

  • Expression Profile of EMT-related Genes and miRNAs Involved in Signal Transduction via the Wnt Pathway and Cadherins in Endometrial Cancer.

    abstract:BACKGROUND:Epithelial-mesenchymal transition (EMT) is a molecular reprogramming that leads to an increased ability to migrate, which can promote invasion and metastasis. EMT can be initiated in response to the activity of signaling pathways such as Wnt as well as miRNAs. OBJECTIVE:The aim of the study was to determine...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666201218125900

    authors: Zmarzły N,Hermyt E,Kruszniewska-Rajs C,Gola J,Witek A,Mazurek U,Ostenda A,Boroń D

    更新日期:2020-12-18 00:00:00

  • Luteolin stimulates proliferation and inhibits late differentiation of primary rat calvarial osteoblast induced by high-dose Dexamethasone via Sema3A /NRP1/Pleixin A1.

    abstract:BACKGROUND:Although Semaphorin 3A (Sema3A)/ Neuropilin-1(NRP1)/Plexin A1 is one of the important targets in bone metabolism, few studies are done on this target in the glucocorticoids-induced osteoporosis. Luteolin is a chemical component of Honeysuckle and it has various bioactivities. The effect and study of Luteolin...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666201216150442

    authors: Zheng L

    更新日期:2020-12-16 00:00:00

  • Inhibition of Melanogenesis by Some Well-Known Polyphenolics: A Review.

    abstract::Melanogenesis is simply defined as production of melanin in melanosomes by melanocytes through a complex process. Melanin, a pigment derived from L-tyrosine, comes into two forms, namely eumelanin (brownish to black) and pheomelanin (red to yellow). Melanin synthesis starts via the hydroxylation of L-tyrosine to L-3,4...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1386207323666201211102233

    authors: Orhan IE,Deniz FSS

    更新日期:2020-12-10 00:00:00

  • Nitrite and Nitrate Levels in Groundwater, Water Distribution Network, Bottled Water and Juices in Iran : A systematic Review.

    abstract:BACKGROUND:Nitrate and nitrite can get into the body through the consumption of contaminated water either directly or indirectly. The accumulation of these compounds in the body, in the long run, leads to health problems, for example, digestive disorders, cancers, and even death threats in children. The aim of this rev...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666201203160012

    authors: Marhamati M,Afshari A,Kiani B,Jannat B,Hashemi M

    更新日期:2020-12-03 00:00:00

  • Synthesis, Characterization and Applications of Spinel Cobaltite Nanomaterials.

    abstract:BACKGROUND:Recently, spinel structures (AB2O4) nanoparticles (NPs) having binary and ternary mixtures of metal oxides were established as promising redox catalysts. Due to the presence of two mixed valence metal cations transport of electrons takes place easily between multiple transition-metal cations with relatively ...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666201117122002

    authors: Patel AR,Sereda G,Banerjee S

    更新日期:2020-11-17 00:00:00

  • Green Synthesis, Spectroscopic Characterization and Biomedical Applications of Carbon Nanotubes.

    abstract::Carbon nanotubes are nano sized cylindrical chicken wire like structures made of carbon atoms. Carbon nanotubes have applications in electronics, energy storage, electromagnetic devices, environmental remediation and in medicine as well. The biomedical applications of carbon nanotubes can be owed to features like low ...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021999201110205615

    authors: Wani TU,Mohi-Ud-Din R,Wani TA,Hassan R,Itoo AM,Sheikh FA,Khan NA,Pottoo FH

    更新日期:2020-11-10 00:00:00

  • Plant derived silver nanoparticles and its therapeutic applications.

    abstract:BACKGROUND:Nanotechnology involves the synthesis of materials that are in nanometre sizes (1 to 100 nm). Nanotechnology has appeared as a new area of fundamental science and is getting worldwide consideration due to its extensive applications. They have exceptional physicochemical properties due to their unique size, s...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666201027155708

    authors: Roy A

    更新日期:2020-10-27 00:00:00

  • Paeoniflorin affects hepatocellular carcinoma progression by inhibiting Wnt/β-catenin pathway through downregulation of 5-HT1D.

    abstract:BACKGROUND:Hepatocellular carcinoma (HCC) is a primary liver cancer with high mortality. Paeoniflorin is a pinane monoterpene picroside with anti-tumor effect isolated from Chinese peony root and white peony root. OBJECTIVE:To investigate the underlying mechanism of paeoniflorin (PF) regulating hepatocellular carcinom...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666201009153808

    authors: Zhou Y,Liu X,Gao Y,Tan R,Wu Z,Zhong Q,Zeng F

    更新日期:2020-10-09 00:00:00

  • Therapeutic potential of non-coding RNAs and TLR signalling pathways in Rheumatoid arthritis.

    abstract:BACKGROUND:Rheumatoid arthritis (RA) is a common connective tissue disease, characteristic of chronic and invasive synovitis in single or multiple joints and vasculitis. RA is a heterogeneous disease with unclear pathogenesis. Therefore, exploring the etiology and pathogenesis of the disease is essential for identifyin...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666201001142829

    authors: Liu J,Wang X,Wang S,Liu F

    更新日期:2020-10-01 00:00:00

  • Effect of oil extract from microalgae (Schizochytrium sp.) on the viability and apoptosis of human osteosarcoma cells.

    abstract:BACKGROUND:Osteosarcoma is a malignant tumor type that starts in bone and occurs most frequently in adolescents. Traditional techniques are insufficient, especially for metastatic ones. As alternative treatment techniques, natural products are worthy to examine due to being safe and innovative. Essential polyunsaturate...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666200928101029

    authors: Sahin D

    更新日期:2020-09-27 00:00:00

  • Biological Aspects and Clinical Applications of Mesenchymal Stem Cells: Key Features You Need to be Aware of.

    abstract::Mesenchymal stem cells (MSCs), a form of adult stem cells, are known to have a self-renewing property and the potential to specialize into a multitude of cells and tissues such as adipocytes, cartilage cells, and fibroblasts. MSCs can migrate and home to the desired target zone where inflammation is present. The uniqu...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666200907121530

    authors: Saeedi M,Nezhad MS,Mehranfar F,Golpour M,Esakandari MA,Rashmeie Z,Ghorbani M,Nasimi F,Hoseinian SN

    更新日期:2020-09-07 00:00:00

  • Nanosuspension as an Efficient Carrier for Improved Ocular Permeation of Voriconazole.

    abstract:BACKGROUND:The present limitations related to the ocular administration of antifungal drugs for the treatment of fungal keratitis include poor ocular bioavailability, limited retention time, and low ocular tissues penetration. METHODS:This study aimed to prepare a novel ophthalmic voriconazole-loaded nanosuspension ba...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021999200820154918

    authors: Qin T,Dai Z,Xu X,Zhang Z,You X,Sun H,Liu M,Zhu H

    更新日期:2020-08-20 00:00:00

  • The Plausible role of Indian Traditional Medicine in combating Corona Virus (SARS-CoV 2): a mini-review.

    abstract::SARS-CoV 2 is a novel virus strain of Coronavirus, reported in China in late December 2019. Its highly contagious nature in humans has prompted WHO to designate the ongoing pandemic as a Public Health Emergency of International Concern. At this moment, there is no specific treatment and the therapeutic strategies to d...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666200807111359

    authors: Adithya J,Nair B,Aishwarya S,Nath LR

    更新日期:2020-08-06 00:00:00

  • Peptides from Euphausia superba Promote Longitudinal Bone Growth by Accelerating Growth Plate Chondrocyte Proliferation and Hypertrophy.

    abstract:BACKGROUND:With the improvements in living standards, height is getting more attention. Malnutrition is one of the main causes of children's short stature, therefore nutritional intervention in adolescence is the key to prevent short stature. The peptides from Antarctic krill (AKPs), the ideal protein model, act in bon...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1381612826666200612170316

    authors: Dai Y,Li Z,Fu M,Li Y,Xue C,Wang J

    更新日期:2020-06-12 00:00:00

  • The Role of the Coagulase-negative Staphylococci (CoNS) in Infective Endocarditis; A Narrative Review from 2000 to 2020.

    abstract::Coagulase-negative staphylococci (CoNS) are part of the microbiota of human skin and rarely linked with soft tissue infections. In recent years, CoNS species considered as one of the major nosocomial pathogens and can cause several infections such as catheter-acquired sepsis, skin infection, urinary tract infection, e...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/1389201021666200423110359

    authors: Noshak MA,Rezaee MA,Hasani A,Mirzaii M

    更新日期:2020-01-01 00:00:00

  • Identification and Molecular Docking Studies of Bioactive Principles from Alphonsea madraspatana Bedd. against Uropathogens.

    abstract:AIMS:The present study aims to determine the antimicrobial efficacy of Alphonsea madraspatana leaves extract against selected uropathogens. BACKGROUND:The plant Alphonsea madraspatana is an endangered species, reported to exhibit high antimicrobial activity due to the presence of phenolic compounds. Prevalence of high...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666200107114846

    authors: Sahu A,Ghosh G,Rath G

    更新日期:2020-01-01 00:00:00

  • Gallic Acid Protects from Acute Multiorgan Injury Induced by Lipopolysaccharide and D-galactosamine.

    abstract:BACKGROUND:Secondary metabolites of plants, the polyphenols, play a vital role in protection from many health problems in human beings. Structurally favored phytochemicals may be studied to protect multiorgan injury. At pharmacological doses, gallic acid is nontoxic to mammals and is generally absorbed in the intestine...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666200615165732

    authors: Rakshit S,Nirala SK,Bhadauria M

    更新日期:2020-01-01 00:00:00

  • Preparation and Characterization of β-glucosidase Films for Stabilization and Handling in Dry Configurations.

    abstract:BACKGROUND:Although the stability of proteins is of significance to maintain protein function for therapeutical applications, this remains a challenge. Herein, a general method of preserving protein stability and function was developed using gelatin films. METHODS:Enzymes immobilized onto films composed of gelatin and...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201020666191202145351

    authors: Zhang L,Shen Y,Lu W,Guo L,Xiang M,Zhang D

    更新日期:2020-01-01 00:00:00

  • Cisplatin Changes Expression of SEMA3B in Endometrial Cancer.

    abstract:BACKGROUND:Semaphorin 3B (SEMA3B) is characterized as a strong suppressing factor of the proliferation of cancerous cells and also by its anti-angiogenic effect. However, the knowledge on the changes in the expression profile of SEMA3B under the influence of cisplatin in endometrial cancer remains fragmented. The aim o...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666200514215839

    authors: Peszek W,Kras P,Grabarek BO,Boroń D,Oplawski M

    更新日期:2020-01-01 00:00:00

  • Formulation and Evaluation of Atorvastatin Calcium-Poly-ε-Caprolactone Nanoparticles Loaded Ocular Inserts for Sustained Release and Antiinflammatory Efficacy.

    abstract:PURPOSE:The work was performed to investigate the feasibility of preparing ocular inserts loaded with Poly-ε-Caprolactone (PCL) nanoparticles as a sustained ocular delivery system. METHODS:First, Atorvastatin Calcium-Poly-ε-Caprolactone (ATC-PCL) nanoparticles were prepared and characterized. Then, the optimized nanop...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666200519133350

    authors: Girgis GNS

    更新日期:2020-01-01 00:00:00

  • In Silico Studies on Anti-Stress Compounds of Ethanolic Root Extract of Hemidesmus indicus L.

    abstract:BACKGROUND:Alternative medicine is available for those diseases which cannot be treated by conventional medicine. Ayurveda and herbal medicines are important alternative methods in which the treatment is done with extracts of different medicinal plants. This work is concerned with the evaluation of anti-stress bioactiv...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666191211152754

    authors: Daddam JR,Sreenivasulu B,Umamahesh K,Peddanna K,Rao DM

    更新日期:2020-01-01 00:00:00

  • The Effects of X-Ray Irradiation on Safety and Nutritional Value of Food: A Systematic Review Article.

    abstract::X-ray is a non-thermal technology that has shown good efficacy in reducing pathogenic and spoilage bacteria, viruses and parasites. X-ray hygiene technology resulted in a high microbial loss in numerous food products, such as dairy products, ready-to-eat shrimp, oysters, fresh products, strawberries, shredded iceberg ...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666200219093834

    authors: Zehi ZB,Afshari A,Noori SMA,Jannat B,Hashemi M

    更新日期:2020-01-01 00:00:00

  • Dihydroorotate Dehydrogenase Inhibitors Promote Cell Cycle Arrest and Disrupt Mitochondria Bioenergetics in Ramos Cells.

    abstract:BACKGROUND:The re-emerging of targeting Dihydroorotate Dehydrogenase (DHODH) in cancer treatment particularly Acute Myelogenous Leukemia (AML) has corroborated the substantial role of DHODH in cancer and received the attention of many pharmaceutical industries. OBJECTIVE:The effects of Brequinar Sodium (BQR) and 4SC-1...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666200611113734

    authors: Kadir MFA,Othman S,Nellore K

    更新日期:2020-01-01 00:00:00

  • Prevalence of Multi-Drug Resistant Tuberculosis among Tuberculosis Patients Attending Chest Clinics in Osun-State, Nigeria.

    abstract:BACKGROUND:The development of multidrug-resistant tuberculosis (MDR-TB) poses a considerable threat to tuberculosis control programmes in Nigeria. There is an increase in the prevalence of MDR-TB worldwide both among new tuberculosis cases as well as previously-treated ones. There is also a rise in transmission of resi...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666200226100242

    authors: Oyedeji GJ,Adeyemo C,Dissou A,Abiodun T,Alli OAT,Onaolapo OJ,Onaolapo AY,Adesiji Y,Olowe OA

    更新日期:2020-01-01 00:00:00

  • Ecofriendly Ethyl Cellulose Microsponges of Citronella Oil: Preparation, Characterization and Evaluation of Cytotoxicity and Larvicidal assay.

    abstract:BACKGROUND:Citronella Oil (CO) was used by the Indian army as mosquito repellant to repel mosquitoes at the beginning of the 20th century and later in 1948, it was registered in the USA for commercial purposes. Due to its ecofriendly nature, CO possesses immense potential as a mosquito repellent. METHODS:Citronella oi...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201020666191120124314

    authors: Sharma R,Kumar N,Singh SP,Kumar S,Rao R

    更新日期:2020-01-01 00:00:00

  • Thymoquinone, an Active Compound of Nigella sativa: Role in Prevention and Treatment of Cancer.

    abstract:BACKGROUND:Cancer is the leading cause of death worldwide and the current mode of cancer treatment causes side effects on normal cells and are still the key challenges in its' treatment. However, natural products or active compounds of medicinal plants have shown to be safe, affordable, and effective in diseases cure. ...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/1389201021666200416092743

    authors: Almatroodi SA,Almatroudi A,Alsahli MA,Khan AA,Rahmani AH

    更新日期:2020-01-01 00:00:00

  • Green and Simple Synthesis of Silver Nanoparticles by Aqueous Extract of Perovskia abrotanoides: Characterization, Optimization and Antimicrobial Activity.

    abstract:BACKGROUND:Herein, we report the biosynthesis procedure to prepare silver nanoparticles as reduction and capping agents with the aqueous plant extract of Perovskia abrotanoides. METHODS:The therapeutic application of silver nanoparticles entirely depends on the size and shape of the nanoparticles therefore, their cont...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201020666190618121218

    authors: Mirsadeghi S,Koudehi MF,Rajabi HR,Pourmortazavi SM

    更新日期:2020-01-01 00:00:00

  • The Possible Role of Pathogenic and Non-Pathogenic Bacteria in Initiation and Exacerbation of Celiac Disease; A Comprehensive Review.

    abstract::Celiac Disease (CD) is an immune-mediated enteropathy, generally of the proximal intestine, that occurs in genetically susceptible individuals triggered by the ingestion of gluten. The incidence and frequency of CD are increasing, and it is predicted that CD affects approximately 1% of the people worldwide. The common...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/1389201021666191219160729

    authors: Azimi T,Nasser A,Shariati A,Shiadeh SMJ,Safari H,Alizade-Sani M,Taghipour A,Dehghan A

    更新日期:2020-01-01 00:00:00

  • Relationship between SNP rs1764391 and Susceptibility, Risk Factors, Gene-environment Interactions of Acute Myocardial Infarction in Guangxi Han Chinese Population.

    abstract:BACKGROUND:Large-scale population studies showed that the SNP rs1764391 of Connexin37 gene also known as Cx37 gene may play a pivotal role in the occurrence and development of acute myocardial infarction (AMI). Published results, however, are highly controversial. OBJECTIVE:This study aimed to examine the association ...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201019666191003150015

    authors: Li J,Qin R,Wang W,Huang Z,Huang DL,Li T,Wang F,Zeng XT,Sun ZY,Liu XF,Huang F,Guo T

    更新日期:2020-01-01 00:00:00

  • Tinospora cordifolia (Giloy): Phytochemistry, Ethnopharmacology, Clinical Application and Conservation Strategies.

    abstract::Tinospora cordifolia (Giloy) is a medicinal plant used in folk and Ayurvedic medicines throughout India since ancient times. All the parts of the plant are immensely useful due to the presence of different compounds of pharmaceutical importance belonging to various groups as alkaloids, diterpenoid lactones, glycosides...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/1389201021666200430114547

    authors: Kumar P,Kamle M,Mahato DK,Bora H,Sharma B,Rasane P,Bajpai VK

    更新日期:2020-01-01 00:00:00

  • Synergistic Effect of Tazobactam on Amikacin MIC in Acinetobacter baumannii Isolated from Burn Patients in Tehran, Iran.

    abstract:BACKGROUND:Burn is still an important global public health challenge. Wound colonization of antibiotic resistant bacteria such as Acinetobacter baumannii can lead to high morbidity and mortality in burn patients. The aim of this study was to evaluate the inhibitory effect of tazobactam on efflux pump, which can cause a...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666200220121122

    authors: Azimi L,Tahbaz SV,Alaghehbandan R,Alinejad F,Lari AR

    更新日期:2020-01-01 00:00:00

  • Effectiveness of Bacteriophage Therapy in Field Conditions and Possible Future Applications.

    abstract:BACKGROUND:Bacteriophages are viruses, which are obligate parasites of specific bacteria for the completion of their lifecycle. Bacteriophages could be the possible alternative to antibioticresistant bacterial diseases. With this objective, extensive research in different fields is published which are discussed in this...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/1389201021666191217111156

    authors: Adhikari N,Acharya KP

    更新日期:2020-01-01 00:00:00

  • Evaluation of Strategies for Decreasing Blood Glucose Using Albuminbinding Domain.

    abstract:OBJECTIVE:Frequent administrations for DPPIV-resistant GLP-1 analogs are necessary to maintain the blood concentrations due to the short half-life of less than 5 minutes. However, most delivery systems that possess the ability of sustainable release of GLP-1 have drawbacks such as low yield, high cost and undesirable s...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666200101105018

    authors: Fan L,Fan Y,Fan H,Huang K

    更新日期:2020-01-01 00:00:00

  • Feasibility Study for Bedside Production of Recombinant Human Acid α-Glucosidase: Technical and Financial Considerations.

    abstract:OBJECTIVE:The high cost of orphan drugs limits their access by many patients, especially in low- and middle-income countries. Many orphan drugs are off-patent without alternative generic or biosimilar versions available. Production of these drugs at the point-of-care, when feasible, could be a cost-effective alternativ...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666200217113049

    authors: Aldosari MH,den Hartog M,Ganizada H,Evers MJW,Mastrobattista E,Schellekens H

    更新日期:2020-01-01 00:00:00

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