Green Synthesis, Spectroscopic Characterization and Biomedical Applications of Carbon Nanotubes.

Abstract:

:Carbon nanotubes are nano sized cylindrical chicken wire like structures made of carbon atoms. Carbon nanotubes have applications in electronics, energy storage, electromagnetic devices, environmental remediation and in medicine as well. The biomedical applications of carbon nanotubes can be owed to features like low toxicity, non-immunogenicity, high in vivo stability and rapid cell entry etc. Carbon nanotubes have great prospect in the treatment of diseases through diagnostic as well as therapeutic approaches. These nanostructures are interesting carriers for delivery and translocation of therapeutic molecules e.g. proteins, peptides, nucleic acids, drugs etc. to various organs like brain, lungs, liver, pancreas etc. Commonly used methods to synthesize carbon nanotubes are arc discharge, chemical vapor deposition, pyrolysis, laser ablation etc. These methods have many disadvantages such as operation at high temperature, use of chemical catalysts, prolonged synthesis time and inclusion of toxic metallic particles in the final product requiring additional purification processes. In order to avoid these setbacks various green chemistry based synthetic methods have been devised e.g. those involving interfacial polymerization, supercritical carbon dioxide drying, plant extract assisted synthesis, water assisted synthesis etc. This review will provide a thorough outlook of the eco-friendly synthesis of carbon nanotubes reported in literature and their biomedical applications. Besides, the most commonly used spectroscopic techniques used for the characterization of carbon nanotubes are also discussed.

journal_name

Curr Pharm Biotechnol

authors

Wani TU,Mohi-Ud-Din R,Wani TA,Hassan R,Itoo AM,Sheikh FA,Khan NA,Pottoo FH

doi

10.2174/1389201021999201110205615

subject

Has Abstract

pub_date

2020-11-10 00:00:00

eissn

1389-2010

issn

1873-4316

pii

CPB-EPUB-111371

pub_type

杂志文章
  • Plant derived silver nanoparticles and its therapeutic applications.

    abstract:BACKGROUND:Nanotechnology involves the synthesis of materials that are in nanometre sizes (1 to 100 nm). Nanotechnology has appeared as a new area of fundamental science and is getting worldwide consideration due to its extensive applications. They have exceptional physicochemical properties due to their unique size, s...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666201027155708

    authors: Roy A

    更新日期:2020-10-27 00:00:00

  • Forage Legumes as Sources of Bioactive Phytoestrogens for Use in Pharmaceutics: A Review.

    abstract:BACKGROUND:Alfalfa and red clover are the most widespread and most important perennial legumes, primarily used as a high-quality feed for livestock. Both alfalfa and red clover, as well as some other plant species from Fabaceae family, are a rich natural source of phytoestrogens, nonsteroidal compounds with an estrogen...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/1389201019666180730165917

    authors: Tucak M,Horvat D,Cupic T,Krizmanic G,Tomas V,Ravlic M,Popovic S

    更新日期:2018-01-01 00:00:00

  • Clinicopathological Significance of Long Non-Coding RNA GHET1 in Human Cancers: A Meta-Analysis.

    abstract:BACKGROUND:Cancer is considered as the main public health problem and the second leading cause of morbidity and mortality worldwide. Numerous environmental-lifestyle related risk factors account for around one-third of cancer deaths. Recently, the key role of lncRNAs has been widely investigated in a variety of disorde...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,meta分析

    doi:10.2174/1389201021999200727163238

    authors: Poursheikhani A,Nokhandani N,Yousefi H,Rad DM,Sahebkar A

    更新日期:2020-01-01 00:00:00

  • Antioxidant Properties of Solenostemma argel Effervescent Tablets.

    abstract:OBJECTIVE:In the present study, Solenostemma argel effervescent tablets were prepared from Argel methanolic extract. METHODS:The tablets were examined for their ability to impede carbon tetrachloride (CCl4)-induced lipid peroxidation in mice liver. The antioxidant activities of the enzymes; super-oxide dismutase (SOD)...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201020666190617165300

    authors: Suliman RS,Ali HS,Alhelal K,Almutairi W,Alnasser S,Omer M,Suliman R,Algebali A

    更新日期:2019-01-01 00:00:00

  • Molecular, Cellular and Pharmaceutical Aspects of Filling Biomaterials During the Management of Extraction Sockets.

    abstract::After a tooth extraction both hard and soft tissues undergo dimensional changes. The use of a ridge preservation technique at the moment of the tooth extraction could help could help to prevent the volume loss, thus simplifying the subsequent prosthetic and/or implant therapy. Some studies were conducted in order to e...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/1389201018666161223152607

    authors: Alfonsi F,Borgia V,Iezzi G,Piattelli A,Covani U,Tonelli P,Barone A

    更新日期:2017-01-01 00:00:00

  • In vitro Studies on Cytotoxic, DNA Protecting, Antibiofilm and Antibacterial Effects of Biogenic Silver Nanoparticles Prepared with Bergenia ciliata Rhizome Extract.

    abstract:BACKGROUND:Many health hazardous diseases are caused by clinical pathogens. Drugresistant microbes are one of the major health problems in the world. To overcome the effect of infectious diseases new antimicrobial agent from nature has been explored which is environmentally friendly, less costly and more effective for ...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 信件

    doi:10.2174/1389201019666180417160049

    authors: Zia G,Sadia H,Nazir S,Ejaz K,Ali S,Ihsan-Ul-Haq,Iqbal T,Khan MAR,Raza A,Andleeb S

    更新日期:2018-01-01 00:00:00

  • Efficient expression and purification of recombinant therapeutic protein candidates, human midkine and pleiotrophin.

    abstract::Midkine is a heparin-binding growth factor that promotes cell growth, survival, and migration. Externally added midkine prevents ventricular remodeling and improves long-term survival after myocardial infarction in the mouse. Preclinical testing of this protein is in progress. Externally added pleiotrophin, a member o...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201014666131226114919

    authors: Murasugi A

    更新日期:2013-01-01 00:00:00

  • Preparation and Characterization of β-glucosidase Films for Stabilization and Handling in Dry Configurations.

    abstract:BACKGROUND:Although the stability of proteins is of significance to maintain protein function for therapeutical applications, this remains a challenge. Herein, a general method of preserving protein stability and function was developed using gelatin films. METHODS:Enzymes immobilized onto films composed of gelatin and...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201020666191202145351

    authors: Zhang L,Shen Y,Lu W,Guo L,Xiang M,Zhang D

    更新日期:2020-01-01 00:00:00

  • Peroxisome proliferator activated receptor α ligands as anticancer drugs targeting mitochondrial metabolism.

    abstract::Tumor cells show metabolic features distinctive from normal tissues, with characteristically enhanced aerobic glycolysis, glutaminolysis and lipid synthesis. Peroxisome proliferator activated receptor α (PPAR α) is activated by nutrients (fatty acids and their derivatives) and influences these metabolic pathways actin...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/1389201011314030009

    authors: Grabacka M,Pierzchalska M,Reiss K

    更新日期:2013-01-01 00:00:00

  • Nutritional and therapeutic potential of Spirulina.

    abstract::Spirulina, a filamentous cyanobacterium, possesses diverse biological activities and nutritional significance due to high concentration of natural nutrients, having bio-modulatory and immuno-modulatory functions. Different Spirulina preparations influence immune system viz. increase phagocytic activity of macrophages,...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/138920105774370607

    authors: Khan Z,Bhadouria P,Bisen PS

    更新日期:2005-10-01 00:00:00

  • Anticancer Potential of Calli Versus Seedling Extracts Derived from Rosmarinus officinalis and Coleus hybridus.

    abstract:BACKGROUND:In Saudi Arabia, the incidence and mortality rates of breast cancer are high. Although current treatments are effective, breast cancer cells develop resistance to these treatments. Numerous studies have demonstrated that active compounds in plant extracts, such as the phenolic compound Rosmarinic Acid (RA), ...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666200318114817

    authors: Albogami S,Darwish H,Abdelmigid HM,Alotaibi S,El-Deen AN,Alnefaie A,Alattas A

    更新日期:2020-01-01 00:00:00

  • Key questions in metastasis: new insights in molecular pathways and therapeutic implications.

    abstract::The metastatic cascade and colonization remains a major challenge in clinical therapeutics. The formation of metastasis has many rate limiting steps. The expression of metastases initiation genes in primary tumors is driven by the need for cell motility, invasiveness, handling the shear stress in the vasculature and l...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/138920111798376996

    authors: Gueron G,De Siervi A,Vazquez E

    更新日期:2011-11-01 00:00:00

  • Structures of TGF-β receptor complexes: implications for function and therapeutic intervention using ligand traps.

    abstract::TGF-β isoforms (TGF-β1, -β2, and -β3) are secreted signaling ligands that stimulate the expression of protein components of the extracellular matrix, regulate the growth and differentiation of epithelial cells, modulate immune cell function, and play roles in the development of several essential organs, including the ...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/138920111798808383

    authors: Hinck AP,O'Connor-McCourt MD

    更新日期:2011-12-01 00:00:00

  • Nucleic-Acid Delivery Using Lipid Nanocapsules.

    abstract::Lipid nanocapsules (LNCs) were designed more than 15 years ago to deliver lipophilic drugs to cells with non toxic excipients by mimicking lipoproteins. During the last 5 years these promising nanocarriers were re-designed to deliver nucleic acids to cancer cells. This short review sums up the features of LNCs and des...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/1389201017666160401145206

    authors: Lagarce F,Passirani C

    更新日期:2016-01-01 00:00:00

  • Tinospora cordifolia (Giloy): Phytochemistry, Ethnopharmacology, Clinical Application and Conservation Strategies.

    abstract::Tinospora cordifolia (Giloy) is a medicinal plant used in folk and Ayurvedic medicines throughout India since ancient times. All the parts of the plant are immensely useful due to the presence of different compounds of pharmaceutical importance belonging to various groups as alkaloids, diterpenoid lactones, glycosides...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/1389201021666200430114547

    authors: Kumar P,Kamle M,Mahato DK,Bora H,Sharma B,Rasane P,Bajpai VK

    更新日期:2020-01-01 00:00:00

  • Promises of apoptosis-inducing peptides in cancer therapeutics.

    abstract::Until recently, most research efforts aimed at developing anti-cancer tools were focusing on small molecules. Alternative compounds are now being increasingly assessed for their potential anti-cancer properties, including peptides and their derivatives. One earlier limitation to the use of peptides was their limited c...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/138920111796117337

    authors: Barras D,Widmann C

    更新日期:2011-08-01 00:00:00

  • Exploring sterol and lipid biology in the functional genomic era.

    abstract::The growing prevalence of disorders of lipid and sterol homeostasis such as obesity and atherosclerosis in Western societies has increased demand for the development of therapies for their prevention and treatment. Crucial for this development is an understanding of the underlying cellular mechanisms which are involve...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/138920112799095329

    authors: Traini M,Jessup W

    更新日期:2012-02-01 00:00:00

  • Current Advances in Food Science & Health Promotion (Part I).

    abstract:: ...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 社论

    doi:10.2174/138920101913190108104855

    authors: Giaginis C

    更新日期:2018-01-01 00:00:00

  • Proliposomes for oral delivery: progress and challenges.

    abstract::Proliposomes are phospholipid based drug delivery systems that are finding important applications in the field of pharmaceutics. Proliposomes have been extensively studied as a potential carrier for oral delivery of drugs with poor bioavailability, but the mechanism of absorption and cellular uptake pathways has not y...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/1389201016666150118134256

    authors: Nekkanti V,Venkatesan N,Betageri GV

    更新日期:2015-01-01 00:00:00

  • Pharmaceutical importance of some promising plant species with special reference to the isolation and extraction of bioactive compounds: A review.

    abstract:BACKGROUND:Active principles from natural sources, in the form of extracts and natural compounds, provide an infinite number of bioactive compounds with consummate disposal of chemical diversity. These compounds and active principles are of utmost importance in the discovery of drugs of biological origin particularly, ...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201022666210122125854

    authors: Das G,Patra JK,Kang SS,Shin HS

    更新日期:2021-01-22 00:00:00

  • The Use of Biomarkers in Sepsis: A Systematic Review.

    abstract:BACKGROUND:Despite the extended laboratory and clinical study of sepsis, its diagnosis remains a clinical challenge. The initiation of sepsis activates many different biochemical and immunological pathways being expressed by alterations of various molecules in human tissues. The detection and measurement of the concent...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/1389201018666170601080111

    authors: Giannakopoulos K,Hoffmann U,Ansari U,Bertsch T,Borggrefe M,Akin I,Behnes M

    更新日期:2017-01-01 00:00:00

  • Immuno-isolation in oncology--a mini-review.

    abstract::Immuno-isolation provides a potentially safe and effective method of delivering recombinant therapeutic molecules. Its application as a drug-delivery platform for the treatment of cancer has shown promising developments recently. This review will summarize the principle and current progress of this novel therapy parad...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/1389201013378680

    authors: Cirone P,Saller RM,Chang PL

    更新日期:2001-09-01 00:00:00

  • Essential oils as active ingredients of lipid nanocarriers for chemotherapeutic use.

    abstract::Essential oils have increased interest as promising ingredients for novel pharmaceutical dosage forms. These oils are reported to provide synergistic effects of their active ingredients, in parallel with their biodegradable properties. In addition, essential oils may also have therapeutic effects in diabetes, inflamma...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/1389201016666150206111253

    authors: Severino P,Andreani T,Chaud MV,Benites CI,Pinho SC,Souto EB

    更新日期:2015-01-01 00:00:00

  • Characterization of protein higher order structure using vibrational circular dichroism spectroscopy.

    abstract::Better understanding of protein higher order structures (HOS) is of major interest to researchers in the field of biotechnology and biopharmaceutics. Monitoring a protein's HOS is crucial towards understanding the impact of molecular conformation on the biotechnological application. In addition, maintaining the HOS is...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201011314020010

    authors: Nagarkar RP,Murphy BM,Yu X,Manning MC,Al-Azzam WA

    更新日期:2013-01-01 00:00:00

  • The Plausible role of Indian Traditional Medicine in combating Corona Virus (SARS-CoV 2): a mini-review.

    abstract::SARS-CoV 2 is a novel virus strain of Coronavirus, reported in China in late December 2019. Its highly contagious nature in humans has prompted WHO to designate the ongoing pandemic as a Public Health Emergency of International Concern. At this moment, there is no specific treatment and the therapeutic strategies to d...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666200807111359

    authors: Adithya J,Nair B,Aishwarya S,Nath LR

    更新日期:2020-08-06 00:00:00

  • Single-molecule detection and probe strategies for rapid and ultrasensitive genomic detection.

    abstract::This paper reviews the current state-of-the-art development of single-molecule detection (SMD)-based methods for ultrasensitive and specific analysis of genomic sequences. We first discuss several newly devised single fluorescent probe strategies that allow separation-free detection of low-abundance DNA sequences, suc...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/138920105775159304

    authors: Yeh HC,Chao SY,Ho YP,Wang TH

    更新日期:2005-12-01 00:00:00

  • Evaluation of Strategies for Decreasing Blood Glucose Using Albuminbinding Domain.

    abstract:OBJECTIVE:Frequent administrations for DPPIV-resistant GLP-1 analogs are necessary to maintain the blood concentrations due to the short half-life of less than 5 minutes. However, most delivery systems that possess the ability of sustainable release of GLP-1 have drawbacks such as low yield, high cost and undesirable s...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1389201021666200101105018

    authors: Fan L,Fan Y,Fan H,Huang K

    更新日期:2020-01-01 00:00:00

  • New developments of clinical trial in immunotherapy for Alzheimer's disease.

    abstract::Active or passive immunotherapy is expected to slow or stop the pathological process of Alzheimer's disease (AD). Immunotherapy for AD has demonstrated that targeting beta-amyloid (Aβ) or tau protein with vaccines or antibodies can reduce AD pathologies. Active anti-Aβ immunization for AD includes using AN1792 and sec...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/138920101606150407112319

    authors: Yang C,Xiao S

    更新日期:2015-01-01 00:00:00

  • Tamarix articulata (T. articulata) - An Important Halophytic Medicinal Plant with Potential Pharmacological Properties.

    abstract:BACKGROUND:Tamarix Articulata (T. articulata), commonly known as Tamarisk or Athal in Arabic region, belongs to the Tamaricaece species. It is an important halophytic medicinal plant and a good source of polyphenolic phytochemical(s). In traditional medicines, T. articulata extract is commonly used, either singly or in...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章,评审

    doi:10.2174/1389201020666190318120103

    authors: Alnuqaydan AM,Rah B

    更新日期:2019-01-01 00:00:00

  • Inhibition of Melanogenesis by Some Well-Known Polyphenolics: A Review.

    abstract::Melanogenesis is simply defined as production of melanin in melanosomes by melanocytes through a complex process. Melanin, a pigment derived from L-tyrosine, comes into two forms, namely eumelanin (brownish to black) and pheomelanin (red to yellow). Melanin synthesis starts via the hydroxylation of L-tyrosine to L-3,4...

    journal_title:Current pharmaceutical biotechnology

    pub_type: 杂志文章

    doi:10.2174/1386207323666201211102233

    authors: Orhan IE,Deniz FSS

    更新日期:2020-12-10 00:00:00