Molecular, Cellular and Pharmaceutical Aspects of Synthetic Hydroxyapatite Bone Substitutes for Oral and Maxillofacial Grafting.

Abstract:

:Bone grafts are widely used for augmentation procedures in oral and maxillofacial surgery, with autogenous bone being the gold standard. Recently, the focus of research has shifted towards synthetic bone substitutes, as no second surgery is needed and large quantities of graft can easily be provided. Within the broad range of bone substitutes, synthetic hydroxyapatite has drawn much attention, as they are considered to be biocompatible, non-immunogenic, osteoconductive and osteoinductive. Scope of this review is to summarize existing knowledge concerning the molecular, cellular and pharmaceutical aspects of synthetic bone substitutes for oral and maxillofacial grafting.

journal_name

Curr Pharm Biotechnol

authors

Gotz W,Papageorgiou SN

doi

10.2174/1389201017666161202103218

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

95-106

issue

1

eissn

1389-2010

issn

1873-4316

pii

CPB-EPUB-80109

journal_volume

18

pub_type

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