Modeling Continuous Admixture Using Admixture-Induced Linkage Disequilibrium.

abstract：:In this study, nanowires/nanowalls were generated on a silicon wafer through a chemical etching method. Octadecyltrichlorosilane (OTS) was deposited onto the nanowire/nanowall surfaces to alter their hydrophobicity. The hydrophobic characteristics of the surfaces were further modified via a 1.5-μm-thick layer of n-oct...

journal_title：Scientific reports

authors： Yilbas BS,Salhi B,Yousaf MR,Al-Sulaiman F,Ali H,Al-Aqeeli N

更新日期：2016-12-09 00:00:00

abstract：:Analysis of intact glycopeptides by mass spectrometry is essential to determining the microheterogeneity of protein glycosylation. Higher-energy collisional dissociation (HCD) fragmentation of glycopeptides generates mono- or disaccharide ions called oxonium ions that carry information about the structure of the fragm...

journal_title：Scientific reports

authors： Toghi Eshghi S,Yang W,Hu Y,Shah P,Sun S,Li X,Zhang H

更新日期：2016-11-21 00:00:00

abstract：:Third permanent molars (M3s) are the last tooth to form but have not been used to estimate age at dental maturation in early fossil hominins because direct histological evidence for the timing of their growth has been lacking. We investigated an isolated maxillary M3 (SK 835) from the 1.5 to 1.8-million-year-old (Mya)...

journal_title：Scientific reports

authors： Dean C,Zanolli C,Le Cabec A,Tawane M,Garrevoet J,Mazurier A,Macchiarelli R

更新日期：2020-11-04 00:00:00

abstract：:Water is the most important plasticizer of biological and organic hydrophilic materials, which generally exhibit enhanced mechanical softness and molecular mobility upon hydration. The enhancement of the molecular dynamics upon mixing with water, which in glass-forming systems implies a lower glass transition temperat...

journal_title：Scientific reports

authors： Ruiz GN,Romanini M,Hauptmann A,Loerting T,Shalaev E,Tamarit JL,Pardo LC,Macovez R

更新日期：2017-08-07 00:00:00

abstract：:Electromagnetic resonances in conducting structures give rise to the enhancement of local fields and extinction efficiencies. Conducting structures are conventionally fabricated with a fixed geometry that determines their resonant response. Here, we challenge this conventional approach by demonstrating the photo-gener...

journal_title：Scientific reports

authors： Georgiou G,Tyagi HK,Mulder P,Bauhuis GJ,Schermer JJ,Rivas JG

更新日期：2014-01-07 00:00:00

abstract：:Soluble oligomeric assemblies of amyloidal proteins appear to act as major pathological agents in several degenerative disorders. Isolation and characterization of these oligomers is a pivotal step towards determination of their pathological relevance. Here we describe the isolation of Type 2 diabetes-associated islet...

journal_title：Scientific reports

authors： Bram Y,Frydman-Marom A,Yanai I,Gilead S,Shaltiel-Karyo R,Amdursky N,Gazit E

更新日期：2014-03-04 00:00:00

abstract：:We introduce a setup which realises a tunable engineered environment for experiments in circuit quantum electrodynamics. We illustrate this concept with the specific example of a quantum bit, qubit, in a high-quality-factor cavity which is capacitively coupled to another cavity including a resistor. The temperature of...

journal_title：Scientific reports

authors： Jones PJ,Huhtamäki JA,Salmilehto J,Tan KY,Möttönen M

更新日期：2013-01-01 00:00:00

abstract：:The global incidence of obesity has led to an increasing need for understanding the molecular mechanisms that drive this epidemic and its comorbidities. Quantitative real-time RT-PCR (RT-qPCR) is the most reliable and widely used method for gene expression analysis. The selection of suitable reference genes (RGs) is c...

journal_title：Scientific reports

authors： Perez LJ,Rios L,Trivedi P,D'Souza K,Cowie A,Nzirorera C,Webster D,Brunt K,Legare JF,Hassan A,Kienesberger PC,Pulinilkunnil T

更新日期：2017-06-15 00:00:00

abstract：:Mineral dust aerosols are responsible for some of the largest sources of uncertainties in our current understanding of climate change. Here we show that a severe drought is having a significant impact in one of largest sources of mineral dust aerosols of the U.S., the Owens Lake area in California's southwest. Measure...

journal_title：Scientific reports

authors： Borlina CS,Rennó NO

更新日期：2017-05-11 00:00:00

abstract：:The intrinsic atomic mechanisms responsible for electronic doping of epitaxial graphene Moirés on transition metal surfaces is still an open issue. To better understand this process we have carried out a first-principles full characterization of the most representative Moiré superstructures observed on the Gr/Pt(111) ...

journal_title：Scientific reports

authors： Martínez JI,Merino P,Pinardi AL,Gonzalo OI,López MF,Méndez J,Martín-Gago JA

更新日期：2016-02-08 00:00:00

abstract：:Choosing an option increases a person's preference for that option. This phenomenon, called choice-based learning (CBL), has been investigated separately in the contexts of internally guided decision-making (IDM, e.g., preference judgment), for which no objectively correct answer exists, and externally guided decision...

journal_title：Scientific reports

authors： Nakao T,Kanayama N,Katahira K,Odani M,Ito Y,Hirata Y,Nasuno R,Ozaki H,Hiramoto R,Miyatani M,Northoff G

更新日期：2016-08-31 00:00:00

abstract：:Gastroenteritis is common among children. Campylobacter jejuni is one of the main causative bacterial pathogens, together with Shigella, Salmonella and invasive Escherichia coli. Campylobacteriosis is a zoonotic, usually self-limited disease that does not always require antibiotic treatment. In cases of protracted dia...

journal_title：Scientific reports

authors： Sakran W,Hexner-Erlichman Z,Spiegel R,Batheesh H,Halevy R,Koren A

更新日期：2020-04-02 00:00:00

abstract：:Lipases are interfacially activated enzymes that catalyze the hydrolysis of ester bonds and constitute prime candidates for industrial and biotechnological applications ranging from detergent industry, to chiral organic synthesis. As a result, there is an incentive to understand the mechanisms underlying lipase activi...

journal_title：Scientific reports

authors： Bohr SS,Lund PM,Kallenbach AS,Pinholt H,Thomsen J,Iversen L,Svendsen A,Christensen SM,Hatzakis NS

更新日期：2019-11-07 00:00:00

abstract：:This study was performed to compare the area of the foveal avascular zone (FAZ-area) obtained by three optical coherence tomography angiography (OCTA) instruments. This was a cross-sectional, non-interventional study of twenty-seven healthy right eyes. The superficial and deep FAZ-area was measured manually with three...

journal_title：Scientific reports

authors： Shiihara H,Sakamoto T,Yamashita T,Kakiuchi N,Otsuka H,Terasaki H,Sonoda S

更新日期：2017-08-29 00:00:00

abstract：:A discrete optical system can broaden the spatial distribution of the input light through optical coupling in array waveguides, just like diffraction in continuous media. Here, we theoretically demonstrate several kinds of control methods of optical field propagation in a discrete optical system, which is composed of ...

journal_title：Scientific reports

authors： Deng H,Yuan Y,Yuan L

更新日期：2017-07-12 00:00:00

abstract：:A bound state in the continuum (BIC) is an unusual localized state that is embedded in a continuum of extended states. Here, we present the general condition for BICs to arise from wave equation separability. Then we show that by exploiting perturbations of certain symmetry such BICs can be turned into resonances that...

journal_title：Scientific reports

authors： Rivera N,Hsu CW,Zhen B,Buljan H,Joannopoulos JD,Soljačić M

更新日期：2016-09-19 00:00:00

abstract：:We previously identified Drosophila REPTOR and REPTOR-BP as transcription factors downstream of mTORC1 that play an important role in regulating organismal metabolism. We study here the mammalian ortholog of REPTOR-BP, Crebl2. We find that Crebl2 mediates part of the transcriptional induction caused by mTORC1 inhibiti...

journal_title：Scientific reports

authors： Tiebe M,Lutz M,Senyilmaz Tiebe D,Teleman AA

更新日期：2019-12-27 00:00:00

abstract：:For a broad class of input-output maps, arguments based on the coding theorem from algorithmic information theory (AIT) predict that simple (low Kolmogorov complexity) outputs are exponentially more likely to occur upon uniform random sampling of inputs than complex outputs are. Here, we derive probability bounds that...

journal_title：Scientific reports

authors： Dingle K,Pérez GV,Louis AA

更新日期：2020-03-10 00:00:00

abstract：:Caspase-3-related DEVDase activity is initiated upon apoptosis in unfertilized starfish eggs. In this study, we cloned a starfish procaspase-3 corresponding to mammalian effector caspase containing a CARD that is similar to the amino terminal CARD of mammalian capsase-9, and we named it procaspase-3/9. Recombinant pro...

journal_title：Scientific reports

authors： Tamura R,Takada M,Sakaue M,Yoshida A,Ohi S,Hirano K,Hayakawa T,Hirohashi N,Yura K,Chiba K

更新日期：2018-01-25 00:00:00

abstract：:Distributed position and orientation systems (DPOSs) can provide abundant time-spatial information for interferometric synthetic aperture radar (InSAR) in airborne earth observation systems. However, some key error terms have not been taken into consideration in the traditional low-order error model, which suppresses ...

journal_title：Scientific reports

authors： Gu B,Ye W,Teng Z,Chen H,Wang G

更新日期：2020-11-24 00:00:00

abstract：:Angiogenesis is one of the hallmarks of cancer and, as such, one of the alternative general targets for anticancer therapy. Since angiogenesis is a complex process involving a high number of interconnected components, a network approach would be a convenient systemic way to analyse responses to directed drug attacks. ...

journal_title：Scientific reports

authors： Montañez R,Sánchez-Jiménez F,Quesada AR,Medina MÁ

更新日期：2011-01-01 00:00:00

abstract：:Body contouring achieved via subcutaneous adipose tissue reduction has notably advanced over the past century, from suction assisted lipectomy to techniques with reduced degrees of invasiveness including laser, radiofrequency, high frequency focused ultrasound, cryolipolysis, and drug-based injection approaches. These...

journal_title：Scientific reports

authors： Pham TT,Stokolosa AM,Borden PA,Hansen KD,Hong EM,Krasieva TB,Sivoraphonh RH,Moy WJ,Heidari AE,Lee LH,Kim EH,Sun CH,Jia W,Mo J-,Kim S,Hill MG,Wong BJF

更新日期：2020-11-27 00:00:00

abstract：:Increasing evidence demonstrates that berberine (BBR) is beneficial for obesity-associated non-alcoholic fatty liver disease (NAFLD). However, it remains to be elucidated how BBR improves aspects of NAFLD. Here we revealed an AMP-activated protein kinase (AMPK)-independent mechanism for BBR to suppress obesity-associa...

journal_title：Scientific reports

authors： Guo T,Woo SL,Guo X,Li H,Zheng J,Botchlett R,Liu M,Pei Y,Xu H,Cai Y,Zeng T,Chen L,Li X,Li Q,Xiao X,Huo Y,Wu C

更新日期：2016-03-03 00:00:00

abstract：:Predation plays a central role in the lives of most organisms. Predators must find and subdue prey to survive and reproduce, whereas prey must avoid predators to do the same. The resultant antagonistic coevolution often leads to extreme adaptations in both parties. Few examples capture the imagination like a rapid str...

journal_title：Scientific reports

authors： Higham TE,Clark RW,Collins CE,Whitford MD,Freymiller GA

更新日期：2017-01-13 00:00:00

abstract：:The interplay between spin states and metallization in compressed CoCl2 is investigated by combining diffraction, resistivity and spectroscopy techniques under high-pressure conditions and ab-initio calculations. A pressure-induced metallization along with a Co2+ high-spin (S = 3/2) to low-spin (S = 1/2) crossover tra...

journal_title：Scientific reports

authors： Barreda-Argüeso JA,Nataf L,Aguado F,Hernández I,González J,Otero-de-la-Roza A,Luaña V,Jia Y,Jin C,Kim B,Kim K,Min BI,Heribert W,Jephcoat AP,Rodríguez F

更新日期：2019-04-01 00:00:00

abstract：:Chemotherapy can cause cachexia, which consists of weight loss associated with muscle atrophy. The exact mechanisms underlying this skeletal muscle toxicity are largely unknown and co-therapies to attenuate chemotherapy-induced side effects are lacking. By using a rat model of cisplatin-induced cachexia, we here chara...

journal_title：Scientific reports

authors： Sirago G,Conte E,Fracasso F,Cormio A,Fehrentz JA,Martinez J,Musicco C,Camerino GM,Fonzino A,Rizzi L,Torsello A,Lezza AMS,Liantonio A,Cantatore P,Pesce V

更新日期：2017-10-12 00:00:00

abstract：:CDK5 Regulatory Subunit-Associated Protein 1-like 1 (CDKAL1) was identified as a susceptibility gene for type 2 diabetes and body mass index in genome-wide association studies. Although it was reported that CDKAL1 is a methylthiotransferase essential for tRNALys(UUU) and faithful translation of proinsulin generated in...

journal_title：Scientific reports

authors： Take K,Waki H,Sun W,Wada T,Yu J,Nakamura M,Aoyama T,Yamauchi T,Kadowaki T

更新日期：2017-08-04 00:00:00

abstract：:Multi-junction (MJ) solar cells are one of the most promising technologies achieving high sunlight to electricity conversion efficiency. Resistive losses constitute one of the main underlying mechanisms limiting their efficiency under high illumination. In this paper, we study, by numerical modeling, the extent to whi...

journal_title：Scientific reports

authors： Zeitouny J,Katz EA,Dollet A,Vossier A

更新日期：2017-05-11 00:00:00

abstract：:Plasmodiophora brassicae causes clubroot disease in cruciferous. In this report, lipid droplets were observed in the resting spores of P. brassicae. 295 lipid droplet-associated proteins were identified and categorized into nine groups. Transcriptome analysis of these proteins during three different zoosporic stages r...

journal_title：Scientific reports

authors： Bi K,He Z,Gao Z,Zhao Y,Fu Y,Cheng J,Xie J,Jiang D,Chen T

更新日期：2016-11-22 00:00:00

abstract：:The detection and characterization of highly enriched uranium (HEU) presents a large challenge in the non-proliferation field. HEU has a low neutron emission rate and most gamma rays are low energy and easily shielded. To address this challenge, an instrument known as the dual-particle imager (DPI) was used with a por...

journal_title：Scientific reports

authors： Hamel MC,Polack JK,Ruch ML,Marcath MJ,Clarke SD,Pozzi SA

更新日期：2017-08-11 00:00:00