Crebl2 regulates cell metabolism in muscle and liver cells.

abstract：:Pulse generation often requires a stabilized cavity and its corresponding mode structure for initial phase-locking. Contrastingly, modeless cavity-free random lasers provide new possibilities for high quantum efficiency lasing that could potentially be widely tunable spectrally and temporally. Pulse generation in rand...

journal_title：Scientific reports

authors： Yao BC,Rao YJ,Wang ZN,Wu Y,Zhou JH,Wu H,Fan MQ,Cao XL,Zhang WL,Chen YF,Li YR,Churkin D,Turitsyn S,Wong CW

更新日期：2015-12-21 00:00:00

abstract：:Lipofectamine reagents are widely accepted as "gold-standard" for the safe delivery of exogenous DNA or RNA into cells. Despite this, a satisfactory mechanism-based explanation of their superior efficacy has remained mostly elusive thus far. Here we apply a straightforward combination of live cell imaging, single-part...

journal_title：Scientific reports

authors： Cardarelli F,Digiacomo L,Marchini C,Amici A,Salomone F,Fiume G,Rossetta A,Gratton E,Pozzi D,Caracciolo G

更新日期：2016-05-11 00:00:00

abstract：:Dickeya zeae is the causal agent of rice foot rot disease, which has recently become a great threat to rice planting countries and regions. The pathogen produces a family of phytotoxins named zeamines that is critical for bacterial virulence, but little is known about the signaling pathways and regulatory mechanisms t...

journal_title：Scientific reports

authors： Lv M,Chen Y,Liao L,Liang Z,Shi Z,Tang Y,Ye S,Zhou J,Zhang L

更新日期：2018-01-10 00:00:00

abstract：:Surface plasmonics from metal nanoparticles have been demonstrated as an effective way of improving the performance of low-efficiency light emitters. However, reducing the inherent losses of the metal nanoparticles remains a challenge. Here we study the enhancement properties by Ag nanoparticles for InGaN/GaN quantum-...

journal_title：Scientific reports

authors： Fadil A,Iida D,Chen Y,Ma J,Ou Y,Petersen PM,Ou H

更新日期：2014-09-22 00:00:00

abstract：:Toll-like receptor 7 (TLR7) mediates autoantigen and viral RNA-induced cytokine production. Increased TLR7 expression in human atherosclerotic lesions suggests its involvement in atherogenesis. Here we demonstrated TLR7 expression in macrophages, smooth muscle cells (SMCs), and endothelial cells from mouse atheroscler...

journal_title：Scientific reports

authors： Liu CL,Santos MM,Fernandes C,Liao M,Iamarene K,Zhang JY,Sukhova GK,Shi GP

更新日期：2017-04-12 00:00:00

abstract：:We study a system of active particles with soft repulsive interactions that lead to an active cluster-crystal phase in two dimensions. We use two different modelizations of the active force - Active Brownian particles (ABP) and Ornstein-Uhlenbeck particles (AOUP) - and focus on analogies and differences between them. ...

journal_title：Scientific reports

authors： Caprini L,Hernández-García E,López C,Marini Bettolo Marconi U

更新日期：2019-11-13 00:00:00

abstract：:Urothelial cells play essential roles in protection of urine exudation and bacterial invasion at the urothelial mucosa, so that defect or damage of urothelial cells associated with urinary tract diseases may cause serious problems. If a sufficient number of functional urothelial cells are prepared in culture and trans...

journal_title：Scientific reports

authors： Inoue Y,Kishida T,Kotani SI,Akiyoshi M,Taga H,Seki M,Ukimura O,Mazda O

更新日期：2019-09-25 00:00:00

abstract：:Immune cell infiltrates in melanoma have important prognostic value. Gene expression analysis may simultaneously quantify numbers and function of multiple immune cell subtypes in formalin-fixed paraffin-embedded (FFPE) tissues. Prior studies report single gene expression can represent individual immune cell subtypes, ...

journal_title：Scientific reports

authors： Kwak M,Erdag G,Slingluff CL Jr

更新日期：2020-10-27 00:00:00

abstract：:Plants traditionally used by farmers to manage livestock ailments could reduce reliance on synthetic antibiotics and anthelmintics but in many cases their chemical composition is unknown. As a case study, we analyzed the metabolite profiles of 17 plant species and 45 biomass samples from agricultural grasslands in Eng...

journal_title：Scientific reports

authors： French KE,Harvey J,McCullagh JSO

更新日期：2018-01-26 00:00:00

abstract：:Methadone maintenance treatment (MMT) can induce impairments in brain function and structure, despite its clinical effectiveness. However, the effect of chronic MMT on brain white matter (WM) is not fully known. Thirty-three MMT patients underwent diffusion tensor imaging (DTI) twice - at the start of the study (Scan1...

journal_title：Scientific reports

authors： Li W,Li Q,Wang Y,Zhu J,Ye J,Yan X,Li Y,Chen J,Liu J,Li Z,Wang W,Liu Y

更新日期：2016-01-22 00:00:00

abstract：:Once activated, the intracellular receptor NLRP3 assembles an inflammasome protein complex that facilitates the caspase-1-mediated maturation of IL-1β and IL-18. Inactive NLRP3 is guarded by a protein complex containing Hsp90. In response to stress stimuli, Hsp90 is released, and NLRP3 can be activated to promote infl...

journal_title：Scientific reports

authors： Piippo N,Korhonen E,Hytti M,Skottman H,Kinnunen K,Josifovska N,Petrovski G,Kaarniranta K,Kauppinen A

更新日期：2018-04-30 00:00:00

abstract：:MRI of hyperpolarized media, such as (129)Xe and (3)He, shows great potential for clinical applications. The optimal use of the available spin polarization requires accurate flip angle calibrations and T1 measurements. Traditional flip angle calibration methods are time-consuming and suffer from polarization losses du...

journal_title：Scientific reports

authors： Zhong J,Ruan W,Han Y,Sun X,Ye C,Zhou X

更新日期：2016-05-12 00:00:00

abstract：:Discovery of novel biomarkers is critical for early diagnosis of acute coronary syndrome (ACS). Serum metabolite profiling of ST-elevation myocardial infarction (STEMI), unstable angina (UA) and healthy controls was performed using gas chromatography mass spectrometry (GC/MS), solid-phase microextraction coupled to ga...

journal_title：Scientific reports

authors： Ali SE,Farag MA,Holvoet P,Hanafi RS,Gad MZ

更新日期：2016-11-08 00:00:00

abstract：:Oxidative stress (OS), mitochondrial dysfunction, and dysregulation of alpha-synuclein (aSyn) homeostasis are key pathogenic factors in Parkinson's disease. Nevertheless, the role of aSyn in mitochondrial physiology remains elusive. Thus, we addressed the impact of aSyn specifically on mitochondrial response to OS in ...

journal_title：Scientific reports

authors： Menges S,Minakaki G,Schaefer PM,Meixner H,Prots I,Schlötzer-Schrehardt U,Friedland K,Winner B,Outeiro TF,Winklhofer KF,von Arnim CA,Xiang W,Winkler J,Klucken J

更新日期：2017-02-22 00:00:00

abstract：:We have studied photoinduced reduction of absorption and emission in p3ht, a semiconducting polymer, and found that the rate of photodegradation (destruction of the constituent thiophene rings) does not correlate with the luminescence intensity and, correspondingly, does not depend on the excited state concentration. ...

journal_title：Scientific reports

authors： Peters VN,Alexander R,Peters DA,Noginov MA

更新日期：2016-09-15 00:00:00

abstract：:The study of postsynaptic excitation to inhibition (E/I ratio) imbalances in human brain diseases, is a highly relevant functional measurement poorly investigated due to postmortem degradation of synaptic receptors. We show that near-simultaneous recording of microtransplanted synaptic receptors after simulated morgue...

journal_title：Scientific reports

authors： Scaduto P,Sequeira A,Vawter MP,Bunney W,Limon A

更新日期：2020-05-25 00:00:00

abstract：:In the rodent auditory system, the primary cortex is subdivided into two regions, both receiving direct inputs from the auditory thalamus: the primary auditory cortex (A1) and the anterior auditory field (AAF). Although neurons in the two regions display different response properties, like response latency, firing thr...

journal_title：Scientific reports

authors： Sołyga M,Barkat TR

更新日期：2019-07-03 00:00:00

abstract：:We consider the electromagnetic response of a topological Weyl semimetal (TWS) with a pair of Weyl nodes in the bulk and corresponding Fermi arcs in the surface Brillouin zone. We compute the frequency-dependent complex conductivities σαβ(ω) and also take into account the modification of Maxwell equations by the topol...

journal_title：Scientific reports

authors： Kargarian M,Randeria M,Trivedi N

更新日期：2015-08-03 00:00:00

abstract：:Understanding source-sink dynamics is important for conservation management, particularly when climatic events alter species' distributions. Following a 2011 'marine heatwave' in Western Australia, we observed high recruitment of the endemic fisheries target species Choerodon rubescens, towards the cooler (southern) e...

journal_title：Scientific reports

authors： Cure K,Thomas L,Hobbs JA,Fairclough DV,Kennington WJ

更新日期：2017-08-17 00:00:00

abstract：:Due to the limitations of current imaging techniques, visualization of lymphatic capillaries within tissue in vivo has been challenging. Here, we present a label-free high resolution optical coherence tomography (OCT) based lymphangiography (OLAG) within human skin in vivo. OLAG enables rapid (~seconds) mapping of lym...

journal_title：Scientific reports

authors： Baran U,Qin W,Qi X,Kalkan G,Wang RK

更新日期：2016-02-19 00:00:00

abstract：:Secreted Protein Acidic and Rich in Cysteine (SPARC)-related modular calcium-binding protein-2 (SMOC2), a secreted matricellular protein, is reported to be involved in various processes related to cancer progression such as regulating the cell cycle, angiogenesis, and invasion. However, its expression and prognostic s...

journal_title：Scientific reports

authors： Kim HS,Choi JH,Lee JY,Kang J,Myung JK,Kim WH,Jang BG

更新日期：2020-03-17 00:00:00

abstract：:Through a geomorphological study relying on statistically assessed classes of hilltop elevations, we reconstruct a suite of paleo-surfaces along the Tiber River Valley north of Rome that we identify as fluvial terraces formed by interplay between global sea-level fluctuations and regional upift. Using biostratigraphic...

journal_title：Scientific reports

authors： Marra F,Florindo F,Petronio C

更新日期：2017-05-31 00:00:00

abstract：:Azoles are antifungal drugs used to treat fungal infections such as candidiasis in humans. Their extensive use has led to the emergence of drug resistance, complicating antifungal therapy for yeast infections in critically ill patients. Combination therapy has become popular in clinical practice as a potential strateg...

journal_title：Scientific reports

authors： Shrestha SK,Fosso MY,Garneau-Tsodikova S

更新日期：2015-11-23 00:00:00

abstract：:The triboelectric nanogenerator (TENG) is a promising device in energy harvesting and self-powered sensing. In this work, we demonstrate a magnetic-assisted TENG, utilizing the magnetic force for electric generation. Maximum power density of 541.1 mW/m(2) is obtained at 16.67 MΩ for the triboelectric part, while the e...

journal_title：Scientific reports

authors： Han M,Zhang XS,Sun X,Meng B,Liu W,Zhang H

更新日期：2014-04-28 00:00:00

abstract：:In the present work, we introduce two new metrics i.e. hydrogen-bond strength and charge-transfer between the donor/acceptor water molecules as a measure of hydrogen-bond rearrangement dynamics. Further, we also employ a simple model based on energy flux through the donor-acceptor water pairs to quantify the extent of...

journal_title：Scientific reports

authors： Ojha D,Karhan K,Kühne TD

更新日期：2018-11-15 00:00:00

abstract：:The Asian citrus psyllid (ACP; Diaphorina citri) is the vector of Candidatus Liberibacter asiaticus (CLas) that is associated with the devastating Huanglongbing (HLB; citrus greening disease). This pest of Asian origin has spread into the Americas and more recently into a few countries in East Africa. During recent su...

journal_title：Scientific reports

authors： Oke AO,Oladigbolu AA,Kunta M,Alabi OJ,Sétamou M

更新日期：2020-06-10 00:00:00

abstract：:We investigated risk factors for postoperative serious adverse events (SAEs) in elderly patients with preoperative chronic hypoxaemia undergone total hip arthroplasty (THA) or hemiarthroplasty and performed an implementation to modify and improve clinical outcome. A retrospective medical record review was performed to...

journal_title：Scientific reports

authors： He L,Zhang R,Yin J,Zhang H,Bu W,Wang F,Zhang F

更新日期：2019-12-16 00:00:00

abstract：:In kidney disease, higher circulating levels of the mineral-regulating hormone fibroblast growth factor (FGF)-23 are predictive of disease progression but direct pathogenic effects on the kidney are unknown. We sought evidence of local renal synthesis in response to unilateral ureteric obstruction in the mouse, and pr...

journal_title：Scientific reports

authors： Smith ER,Tan SJ,Holt SG,Hewitson TD

更新日期：2017-06-13 00:00:00

abstract：:The aim of this study was to investigate the value of multiple parameters retrieved from the FDG PET/CT studies, including SUVmax, SUVmean, SUVpeak, MTV, TLG, tumour size in differentiating retroperitoneal paragangliomas from UCD. 28 patients with solitary retroperitoneal masses who had undergone preoperative 18F-FDG ...

journal_title：Scientific reports

authors： Jiang Y,Hou G,Zhu Z,Huo L,Li F,Cheng W

更新日期：2020-07-30 00:00:00

abstract：:Natural and anthropogenic stressors can cause phase shifts from coral-dominated to algal-dominated states. In the Caribbean, over-fishing of large herbivorous fish and disease among the long-spined urchin, Diadema, have facilitated algal growth on degraded reefs. We found that diminutive species of urchin and parrotfi...

journal_title：Scientific reports

authors： Kuempel CD,Altieri AH

更新日期：2017-01-05 00:00:00