Abstract：
:Fibromyalgia (FM) is a common and often debilitating chronic pain condition. Research shows that symptoms of depression and anxiety are present in up to three quarters of individuals with FM. Of concern, most adults with FM cannot access traditional face-to-face cognitive behavioural pain management programs, which are known to be beneficial. Given known difficulties with treatment access, the present study sought to explore the efficacy and acceptability of a previously developed Internet-delivered cognitive behavioural pain management course, the Pain Course, for adults with FM. The five-lesson course was delivered over eight weeks and was provided with brief weekly contact, via telephone and secure email, with a guide throughout the course. Participants were randomized either to the Pain Course (n = 30) or to a waiting-list control group (n = 30). Symptoms were assessed at pre-treatment, post-treatment and 4-week follow-up. Completion rates (87%) and satisfaction ratings (86%) were high. Improvements were significantly greater in treatment group participants compared to waiting-list group participants on measures of FM (Cohen's d =.70; 18% reduction), depression (Cohen's d =.63-.72; 20-28% reduction), pain (Cohen's d =.87; 11% improvement) and fear of pain (Cohen's d =1.61; 12% improvement). Smaller effects were also observed on measures of generalized anxiety and physical health. The changes were maintained at four-week follow-up. The current findings add to existing literature and highlight the specific potential of Internet-delivered cognitive behavioural pain management programs for adults with FM, especially as a part of stepped-care models of care. Future research directions are described.
journal_name
Painjournal_title
Painauthors
Friesen LN,Hadjistavropoulos HD,Schneider LH,Alberts NM,Titov N,Dear BFdoi
10.1097/j.pain.0000000000000802subject
Has Abstractpub_date
2017-04-01 00:00:00pages
593-604issue
4eissn
0304-3959issn
1872-6623pii
00006396-201704000-00007journal_volume
158pub_type
杂志文章相关文献
PAIN文献大全abstract：:Chronic pain is currently considered a public health problem with high costs to the individual and society. To improve prevention and treatment of chronic pain, epidemiologic studies are mandatory for assessing chronic pain. The aims of this study were to estimate the prevalence of chronic pain in the adult Danish pop...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2012.07.023
更新日期：2012-12-01 00:00:00
abstract：:Extraterritorial spread of sensory symptoms is frequent in carpal tunnel syndrome (CTS). Animal models suggest that this phenomenon may depend on central sensitization. We sought to obtain psychophysical evidence of sensitization in CTS with extraterritorial symptoms spread. We recruited 100 unilateral CTS patients. A...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2009.10.025
更新日期：2010-02-01 00:00:00
abstract：:Previous work has suggested an attenuated sensitivity to painful stimulation in hypertensive men. We recently reported that, compared with persons with negative parental history, men, but not women, with a positive history for hypertension showed attenuated pain perception. This study specifically addressed factors th...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(00)00306-7
更新日期：2000-10-01 00:00:00
abstract：:Growing evidence suggests that leukocyte extravasation is initiated by the interaction of selectins with their ligands; as well as an essential role for P-selectin in the initial recruitment of inflammatory cells to sites of inflammation. In this study, P-selectin-deficient (P-sel-/-) mice were used to test the hypoth...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2013.06.042
更新日期：2013-10-01 00:00:00
abstract：:Two models of the relationship between paraspinal EMG and low back pain have been proposed. Specific predictions arising from these are listed and the literature relating to them reviewed. Recent research on patterns of EMG rather than absolute levels is also discussed. It is concluded that there is no consistent evid...
journal_title：Pain
pub_type： 杂志文章,评审
doi：10.1016/0304-3959(84)90093-9
更新日期：1984-10-01 00:00:00
abstract：:Alterations in sensory processing have been demonstrated in chronic low back and neck pain. However, it has not been yet systematically summarized how early these changes occur in spinal pain. This systematic review examines the available literature measuring somatosensory function in acute (<6 weeks) and subacute (6-...
journal_title：Pain
pub_type： 杂志文章,meta分析,评审
doi：10.1097/01.j.pain.0000460300.10583.f6
更新日期：2015-02-01 00:00:00
abstract：:The clinical and neurochemical association between depression and season noted in seasonal affective disorder (SAD) has suggested that clinical pain might also be linked to season, perhaps through similar neurochemistry or the known association of depression with pain. We investigated the pain-light season/dark season...
journal_title：Pain
pub_type： 临床试验,杂志文章
doi：10.1016/0304-3959(94)90075-2
更新日期：1994-11-01 00:00:00
abstract：:Fourteen patients whose post-herpetic neuralgia could not be alleviated by conventional methods were treated with cryocautery using a stick of solid carbon dioxide (dry ice) applied directly to the hyperesthetic skin areas of the cutaneous scars. Follow-up evaluation revealed that 5 of 14 subjects maintained excellent...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(80)90049-4
更新日期：1980-12-01 00:00:00
abstract：:Pain stimulates some behaviors (e.g., withdrawal responses) but depresses many other behaviors (e.g., feeding). Pain-stimulated behaviors are widely used in preclinical research on pain and analgesia, but human and veterinary medicine often rely on measures of functional impairment and pain-depressed behavior to diagn...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2009.04.010
更新日期：2009-07-01 00:00:00
abstract：:Chronic pain after laparoscopic cholecystectomy is related to postoperative pain during the first postoperative week, but it is unknown which components of the early pain response is important. In this prospective study, 100 consecutive patients were examined preoperatively, 1 week postoperatively, and 3, 6, and 12 mo...
journal_title：Pain
pub_type： 杂志文章,多中心研究
doi：10.1016/j.pain.2014.09.019
更新日期：2014-11-01 00:00:00
abstract：:This study compared a remote-delivered pain management program, the Pain Course, when delivered in online and workbook formats. Participants (n = 178) were randomised into 2 groups: (1) an Internet Group (n = 84) who were provided with secure accounts to the program in an online format; or (2) a Workbook Group (n = 94...
journal_title：Pain
pub_type： 杂志文章,随机对照试验
doi：10.1097/j.pain.0000000000000916
更新日期：2017-07-01 00:00:00
abstract：:Though it is clear that genomic variability plays an integral role in accounting for pain sensitivity, controversy exists over which genes are involved. While recent data suggest a "protective" (i.e., less pain) haplotype in the GTP cyclohydrolase (GCH1) gene, other research has failed to confirm this association. Pos...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2008.10.023
更新日期：2009-01-01 00:00:00
abstract：:Chronic severe cervico-facial pain syndrome associated with a whiplash-type injury was successfully treated with epidural spinal cord stimulation. The patient had been in pain for 9 years, responding temporarily only to stellate ganglion blocks. The patient has now been painless for 18 months. We have been unable to f...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(98)00218-8
更新日期：1999-03-01 00:00:00
abstract：:Previous work in this laboratory has indicated that the transplantation of adrenal medullary tissue into the subarachnoid space of the rat spinal cord can reduce pain sensitivity to acute noxious stimuli, particularly following stimulation by nicotine. This most likely results from the stimulated release of opioid pep...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(90)91093-X
更新日期：1990-07-01 00:00:00
abstract：:Pain is a frequently observed non-motor symptom of patients with Parkinson's disease. In some patients, Parkinson's-related pain responds to dopaminergic treatment. In the present study, we aimed to elucidate whether subthalamic deep brain stimulation has a similar beneficial effect on pain in Parkinson's disease, and...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2013.03.008
更新日期：2013-08-01 00:00:00
abstract：:(1) Capsaicin solution was applied for 15 min around a 1 cm length of sciatic nerve in the mid upper leg of adult rats. (2) Electron microscopic examinations of the nerve in the treated region after 14 days shows no signs of degeneration of either myelinated or unmyelinated fibres attributable to the capsaicin. (3) Fl...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(81)90637-0
更新日期：1981-12-01 00:00:00
abstract：:Although calcitonin gene-related peptide (CGRP) has been shown to be elevated in jugular venous blood of adult migraineurs during acute migraine attacks, it remains unknown whether CGRP is increased outside of attacks in jugular or cubital venous blood. The aim of the present study was to compare interictal plasma lev...
journal_title：Pain
pub_type： 临床试验,杂志文章
doi：10.1016/s0304-3959(00)00232-3
更新日期：2000-05-01 00:00:00
abstract：:Since many people with chronic fatigue present with pain and many people with chronic pain present with fatigue, we tested if fatigue would enhance the response to pain in male and female mice. We further tested for the activation of brainstem nuclei by the fatigue task using c-fos as a marker. Fatigue was induced by ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2009.07.001
更新日期：2010-02-01 00:00:00
abstract：:A visual analog scale (VAS) method of assessing headache pain was compared with a standard categorical four-grade scale (4GS) in a randomized, placebo-controlled, double-blind, clinical trial involving 792 treated migraine outpatients who received oral rizatriptan 5 mg, sumatriptan 50 mg, or placebo for a moderate or ...
journal_title：Pain
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/S0304-3959(01)00315-3
更新日期：2001-08-01 00:00:00
abstract：:Attenuation of neuropathic manifestations in experimental animals, by lidocaine injection in the rostral ventro-medial medulla (RVM), has been traditionally attributed to selective block of a descending pain facilitatory system. However, the presence of descending fibers carrying this effect and the selective action o...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2010.01.014
更新日期：2010-04-01 00:00:00
abstract：:Migraine encompasses a broader spectrum of sensory symptoms than just headache. These "other" symptoms, eg, sensory phobias, cognitive and mood changes, allodynia, and many others indicate an altered sensitivity to sensory input which can be measured, in principle, by quantifying sensory threshold changes longitudinal...
journal_title：Pain
pub_type： 杂志文章,评审
doi：10.1097/j.pain.0000000000001531
更新日期：2019-07-01 00:00:00
abstract：:Recent studies have suggested that spouses of chronic pain patients are at risk for emotional and marital maladjustment. This study explored the role of patient and spouse gender in mediating the effects of chronic pain on the spouse's adjustment. Eight-three chronic low back pain patients and their spouses completed ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(89)90042-0
更新日期：1989-12-01 00:00:00
abstract：:A secondary zone of cutaneous hyperalgesia in humans is characterized by increased pain to mechanical stimuli. In contrast, the perception of heat stimuli delivered to a secondary zone of hyperalgesia in humans often shows a paradoxical decrease in magnitude. A number of studies have shown that the responses of spinal...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(98)00079-7
更新日期：1998-08-01 00:00:00
abstract：:The ability to sense visceral pain during appendicitis is diminished with age leading to delay in seeking health care and poorer clinical outcomes. To understand the mechanistic basis of this phenomenon, we examined visceral nociception in aged mouse and human tissue. Inflamed and noninflamed appendixes were collected...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000001764
更新日期：2020-04-01 00:00:00
abstract：:Many chronic pain syndromes, including fibromyalgia (FM), show evidence of central nervous system hyperexcitability related to central sensitization. Windup (WU) of second pain reflects increased excitability of spinal cord neurons that is related to central sensitization. Psychophysical testing can help characterize ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2004.05.009
更新日期：2004-08-01 00:00:00
abstract：:Indicators of persistent pain in preterm neonates are poorly defined. In the setting of a double blind, placebo-controlled trial investigating morphine use in ventilated preterm infants (NEOPAIN Trial) we aimed to identify factors that may be useful in assessing persistent pain. Twenty-two babies (morphine 12; placebo...
journal_title：Pain
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.pain.2006.03.019
更新日期：2006-09-01 00:00:00
abstract：:Endogenous TRPV1 agonists such as oxidized linoleic acid metabolites (OLAMs) and the enzymes releasing them [eg, cytochrome P450 (CYP)] are up-regulated after inflammation in the rat. However, it is not known whether such agonists are elevated in human inflammatory pain conditions. Because TRPV1 is expressed in human ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2013.07.011
更新日期：2013-11-01 00:00:00
abstract：:In a double-blind, crossover study, the effects of 75 mg amitriptyline alone during 5 weeks on pain intensity were compared with the effects of a combination of 75 mg amitriptyline and 3 mg flupentixol during 5 weeks in 34 patients with somatoform pain disorder. Both treatments resulted in a statistically significant ...
journal_title：Pain
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0304-3959(91)90007-K
更新日期：1991-10-01 00:00:00
abstract：:In preparation for a series of electrophysiological experiments in a model of neuropathic pain, the present spinal reflex study was done to determine the optimal time after sciatic nerve constriction in the rat for tactile allodynia and to determine also the appropriate 'control' for the nerve constriction model. Ther...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(99)00085-8
更新日期：1999-10-01 00:00:00
abstract：:In rats anesthetized with sodium pentobarbital, we quantitatively analyzed descending modulation from the midbrain of a nociceptive flexion withdrawal reflex and responses of associated spinal neurons. We monitored the isometric force of hind limb withdrawal elicited by noxious heat stimuli (42-54 degrees C, 10 sec) o...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(92)90061-F
更新日期：1992-02-01 00:00:00
