Abstract:
:Chronic pain after laparoscopic cholecystectomy is related to postoperative pain during the first postoperative week, but it is unknown which components of the early pain response is important. In this prospective study, 100 consecutive patients were examined preoperatively, 1 week postoperatively, and 3, 6, and 12 months postoperatively for pain, psychological factors, and signs of hypersensitivity. Overall pain, incisional pain (somatic pain component), deep abdominal pain (visceral pain component), and shoulder pain (referred pain component) were registered on a 100-mm visual analogue scale during the first postoperative week. Nine patients developed chronic unexplained pain 12 months postoperatively. In a multivariate analysis model, cumulated visceral pain during the first week and number of preoperative biliary pain attacks were identified as independent risk factors for unexplained chronic pain 12 months postoperatively. There were no consistent signs of hypersensitivity in the referred pain area either pre- or postoperatively. There were no significant associations to any other variables examined. The risk of chronic pain after laparoscopic cholecystectomy is relatively low, but significantly related to the visceral pain response during the first postoperative week.
journal_name
Painjournal_title
Painauthors
Blichfeldt-Eckhardt MR,Ording H,Andersen C,Licht PB,Toft Pdoi
10.1016/j.pain.2014.09.019subject
Has Abstractpub_date
2014-11-01 00:00:00pages
2400-7issue
11eissn
0304-3959issn
1872-6623pii
S0304-3959(14)00442-4journal_volume
155pub_type
杂志文章,多中心研究相关文献
PAIN文献大全abstract::Patients with acute whiplash trauma were followed to examine if post-trauma ratings of pre-collision pain and psychological distress were associated with reduced work capability and neck pain at 12 months follow-up. The study included 740 consecutive patients (474 females, 266 males) referred from emergency department...
journal_title:Pain
pub_type: 杂志文章,多中心研究
doi:10.1016/j.pain.2008.04.008
更新日期:2008-10-15 00:00:00
abstract::The responses of primate spinothalamic tract (STT) neurons to innocuous and noxious mechanical stimuli applied to the skin can be enhanced for more than an hour following prolonged noxious stimulation. This increased responsiveness is thought to reflect sensitization of dorsal horn neurons and may help account for sec...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(94)90164-3
更新日期:1994-03-01 00:00:00
abstract::This study critically examines the reported exercise-induced analgesia effect in view of the potential stress-induced analgesia of pain testing itself. Two designs were used to test whether previous findings of analgesia were induced by the exercise procedures or by the stress of the pain testing procedures themselves...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(92)90048-G
更新日期:1992-02-01 00:00:00
abstract::A study of the extent of sympathetic blockade after stellate ganglion block was assessed using liquid crystal thermography. Two volumes (10 and 20 ml) of bupivacaine 0.5% plain were used. Irrespective of the volume used cranial sympathetic block always occurred and thoracic sympathetic block never occurred. While uppe...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(89)90023-7
更新日期:1989-02-01 00:00:00
abstract::The purpose of this study was to assess the hypothesis that pain and depression negatively impact the cognitive functioning of individuals with rheumatoid arthritis (RA). One hundred twenty-one community-dwelling RA patients (ages 34-84) completed a battery of cognitive tasks and multiple measures of pain and depressi...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/S0304-3959(01)00457-2
更新日期:2002-04-01 00:00:00
abstract::The present study examined the relationship between depression and a constellation of pain-related variables that describe the experience of chronic pain patients. Thirty-seven depressed and 32 non-depressed heterogeneous chronic pain patients were identified through structured interviews, use of standardized criteria...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(91)90073-7
更新日期:1991-08-01 00:00:00
abstract::Catechol-O-methyltransferase (COMT) regulates extracellular catecholamines. A widely studied COMT single nucleotide polymorphism (rs4680) changes the translated amino acid from valine to methionine (Val158Met); the polymorphism has been shown to influence opioid use. The aims of this study were to investigate the infl...
journal_title:Pain
pub_type: 杂志文章
doi:10.1097/j.pain.0000000000001400
更新日期:2019-01-01 00:00:00
abstract::The objective of this study was to examine which factors during pregnancy and postpartum predict pelvic girdle pain (PGP) at 12 weeks postpartum among working women. A total of 548 Dutch pregnant employees were recruited in 15 companies, mainly health care, child care, and supermarkets. The definition of PGP was any p...
journal_title:Pain
pub_type: 杂志文章,多中心研究
doi:10.1016/j.pain.2012.08.003
更新日期:2012-12-01 00:00:00
abstract::Ten healthy subjects (four male) of mean age 31 years (range 25-40) took part in a randomized double-blind four-way crossover study to examine the cognitive and psychomotor effects of repeated oral doses of dextropropoxyphene and morphine. Four treatments were compared: dextropropoxyphene napsylate 100 mg, morphine su...
journal_title:Pain
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0304-3959(99)00274-2
更新日期:2000-03-01 00:00:00
abstract::Antinociceptive effects of the 2 (each 1000 mg, orally) non-steroidal anti-inflammatory drugs (NSAIDs) acetaminophen (paracetamol) and antipyrine (phenazone) were investigated with a non-inflammatory experimental pain model in 32 healthy volunteers. Phasic pain was induced by intracutaneously applied brief electrical ...
journal_title:Pain
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0304-3959(92)90165-8
更新日期:1992-08-01 00:00:00
abstract::In primary care and physical therapy settings, we evaluated an intervention for chronic back pain patients which incorporated fear reducing and activating techniques. Primary care patients seen for back pain in primary care were screened to identify persons with significant activity limitations 8-10 weeks after their ...
journal_title:Pain
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.pain.2004.11.007
更新日期:2005-02-01 00:00:00
abstract::We investigated the effects of acute and of chronic morphine treatment on T-lymphocyte function and natural killer (NK) cell activity in rats receiving chronic constriction injury (CCI) of the sciatic nerve. T-Lymphocyte function was evaluated based on concanavalin-A (ConA)- and phytohemagglutinin (PHA)-induced spleno...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/S0304-3959(00)00323-7
更新日期:2000-11-01 00:00:00
abstract::Eight patients with established lower limb postamputation stump pain were given lumbar intrathecal fentanyl 25 micrograms and lidocaine 70 mg 2 weeks apart in an attempt to better understand the role of peripheral and central mechanisms in this condition. Baseline pain was recorded and then analgetic and side effects ...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(90)90064-K
更新日期:1990-02-01 00:00:00
abstract::Clinical trial participants often require additional instruction to prevent idiosyncratic interpretations regarding completion of patient-reported outcomes. The Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks (ACTTION) public-private partnership developed a tr...
journal_title:Pain
pub_type: 杂志文章,随机对照试验
doi:10.1097/j.pain.0000000000000502
更新日期:2016-05-01 00:00:00
abstract::Intrathecal (i.t.) administration of spermine (0.1-10000 fmol), an endogenous polyamine, produced the behavioural response mainly consisting of biting and/or licking of the hindpaw along with a slight hindlimb scratching directed toward the flank in mice, which peaked at 5-15 min and almost disappeared at 30 min after...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/s0304-3959(99)00312-7
更新日期:2000-05-01 00:00:00
abstract::In this study, we examined the relationship between astrocyte activation in the cuneate nucleus (CN) and behavioral hypersensitivity after chronic constriction injury (CCI) of the median nerve. In addition, we also examined the effects of pre-emptive treatment with a number of drugs on astrocyte activation and hyperse...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2009.11.004
更新日期:2010-01-01 00:00:00
abstract::We report findings from clinical examination and cutaneous laser stimulation in a 57-year-old male, who suffered from a right-sided postcentral stroke. In this patient, we were able to demonstrate (i) a dissociation of discriminative and affective components of pain perception and, for the first time in humans, (ii) t...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/s0304-3959(99)00012-3
更新日期:1999-05-01 00:00:00
abstract::Clinical pain syndromes, and experimental assays of nociception, are differentially affected by manipulations such as drug administration and exposure to environmental stress. This suggests that there are different 'types' of pain. We exploited genetic differences among inbred strains of mice in an attempt to define t...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/s0304-3959(98)00196-1
更新日期:1999-03-01 00:00:00
abstract::We investigated the efficacy of local intraplantar (i.pl.) injection of peptide and non-peptide mu-, delta- and kappa-opioid receptor agonists in rat models of inflammatory and neuropathic pain. Locally applied agonists dose-dependently reduced formalin-induced flinching of the inflamed paw and induced antiallodynic a...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2008.12.006
更新日期:2009-02-01 00:00:00
abstract::This study evaluated the pre-emptive analgesic effect of intravenous (i.v.) ketorolac (KET) for total hip replacement (THR). Sixty patients who underwent surgery for THR under general anesthesia were randomly allocated to 3 groups. Two i.v. injections were administered: one before induction and one after surgery. The ...
journal_title:Pain
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0304-3959(94)00184-G
更新日期:1995-05-01 00:00:00
abstract::Heat shock protein 90 (Hsp90) is a ubiquitous signal transduction regulator, and Hsp90 inhibitors are in clinical development as cancer therapeutics. However, there have been very few studies on the impact of Hsp90 inhibitors on pain or analgesia, a serious concern for cancer patients. We previously found that Hsp90 i...
journal_title:Pain
pub_type: 杂志文章
doi:10.1097/j.pain.0000000000001886
更新日期:2020-08-01 00:00:00
abstract::Polyneuropathy can be linked to chronic pain but also to reduced pain sensitivity. We investigated peripheral C-nociceptors in painful and painless polyneuropathy patients to identify pain-specific changes. Eleven polyneuropathy patients with persistent spontaneous pain and 8 polyneuropathy patients without spontaneou...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2012.05.017
更新日期:2012-10-01 00:00:00
abstract::Patients with chronic low back pain (LBP) frequently demonstrate high scores for fear-avoidance beliefs and distress. We need better knowledge about fear-avoidance beliefs and distress in early stages of LBP. The objectives of this study were to compare the level of fear-avoidance beliefs and distress in patients with...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/j.pain.2004.09.020
更新日期:2004-12-01 00:00:00
abstract::Bone is one of the leading sites of metastasis for frequently diagnosed malignancies, including those arising in the breast, prostate and lung. Although these cancers develop unnoticed and are painless in their primary sites, bone metastases result in debilitating pain. Deeper investigation of this pain may reveal eti...
journal_title:Pain
pub_type: 杂志文章
doi:10.1097/j.pain.0000000000000681
更新日期:2016-11-01 00:00:00
abstract::A comprehensive treatment program for chronic disability related to back disease has been presented. This program has used not only more traditional methods of medical care for the structural disabilities of chronic mechanical back disorders, but has used principles of active patient participation in the improvement p...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(76)90007-5
更新日期:1976-09-01 00:00:00
abstract::A previous study of this laboratory showed that an acute myositis (which is associated with increased activity in slowly conducting muscle afferent fibres) is followed by marked excitability changes in the dorsal horn within a few hours. The present work addresses the question as to how the responsiveness of dorsal ho...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(94)00105-N
更新日期:1995-02-01 00:00:00
abstract::A survey of the psychological characteristics of a large sample of chronic headache cases (n = 360), including classical and common migraine and tension headache sufferers, was carried out. Comparing groups defined in terms of the chronicity of their headache problems, it was found that those with a longer history of ...
journal_title:Pain
pub_type: 杂志文章
doi:10.1016/0304-3959(85)90286-6
更新日期:1985-02-01 00:00:00
abstract::The superficial dorsal horn, which is the main target for nociceptive and pruritoceptive primary afferents, contains a high density of excitatory interneurons. Our understanding of their roles in somatosensory processing has been restricted by the difficulty of distinguishing functional populations among these cells. ...
journal_title:Pain
pub_type: 杂志文章
doi:10.1097/j.pain.0000000000000778
更新日期:2017-03-01 00:00:00
abstract::Studies on the efficacy of ketamine in the treatment of chronic pain indicate that prolonged or repetitive infusions are required to ensure prolonged pain relief. Few studies address ketamine-induced toxicity. Here we present data on the occurrence of ketamine-induced liver injury during repeated administrations of S(...
journal_title:Pain
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.pain.2011.03.026
更新日期:2011-09-01 00:00:00
abstract::Cognitive strategies have received considerable interest in pain management, alongside the traditional approaches of physical intervention and behavior modification. However, the literature on these strategies is ridden with inconsistencies of terminology that present major difficulties in the conceptualization and ev...
journal_title:Pain
pub_type: 杂志文章,评审
doi:10.1016/0304-3959(86)90070-9
更新日期:1986-08-01 00:00:00