Y chromosome haplogroups based genome-wide association study pinpoints revelation for interactions on non-obstructive azoospermia.

abstract：:The life-like fidelity of organisms captured in amber is unique among all kinds of fossilization and represents an invaluable source for different fields of palaeontological and biological research. One of the most challenging aspects in amber research is the study of traits related to behaviour. Here, indirect eviden...

journal_title：Scientific reports

authors： Stebner F,Szadziewski R,Rühr PT,Singh H,Hammel JU,Kvifte GM,Rust J

更新日期：2016-10-04 00:00:00

abstract：:Given the complex nature of the interaction between gas and solid atoms, the development of nanoscale science and technology has engendered a need for further understanding of gas transport behavior through nanopores and more tractable models for large-scale simulations. In the present paper, we utilize molecular dyna...

journal_title：Scientific reports

authors： Wu T,Zhang D

更新日期：2016-03-29 00:00:00

abstract：:The physiological, biochemical and functional differences between oxidative and glycolytic muscles play important roles in human metabolic health and in animal meat quality. To explore these differences, we determined the genome-wide landscape of DNA methylomes and their relationship with the mRNA and miRNA transcript...

journal_title：Scientific reports

authors： Shen L,Du J,Xia Y,Tan Z,Fu Y,Yang Q,Li X,Tang G,Jiang Y,Wang J,Li M,Zhang S,Zhu L

更新日期：2016-08-26 00:00:00

abstract：:Optical projection tomography (OPT) is a tool used for three-dimensional imaging of millimeter-scale biological samples, with the advantage of exhibiting isotropic resolution typically in the micron range. OPT can be divided into two types: transmission OPT (tOPT) and emission OPT (eOPT). Compared with eOPT, tOPT disc...

journal_title：Scientific reports

authors： Fang M,Dong D,Zeng C,Liang X,Yang X,Arranz A,Ripoll J,Hui H,Tian J

更新日期：2016-01-11 00:00:00

abstract：:Signaling by members of the transforming growth factor-β (TGF-β) superfamily, such as TGF-β3 and BMP7, and oxygen tension play a pivotal role in chondrocyte biology. The objective of this research was to investigate the endogenous BMP7 expression in human osteoarthritis (OA) cartilage and the effect of oxygen tension ...

journal_title：Scientific reports

authors： Huang X,Zhong L,Post JN,Karperien M

更新日期：2018-07-06 00:00:00

abstract：:Smoking is a major risk factor for chronic obstructive pulmonary disease (COPD); however, more than 25% of COPD patients are non-smokers, and gene-by-smoking interactions are expected to affect COPD onset. We aimed to identify the common genetic variants interacting with pack-years of smoking on FEV1/FVC ratios in ind...

journal_title：Scientific reports

authors： Park B,An J,Kim W,Kang HY,Koh SB,Oh B,Jung KJ,Jee SH,Kim WJ,Cho MH,Silverman EK,Park T,Won S

更新日期：2020-08-04 00:00:00

abstract：:We present a combined experimental and theoretical study of the electronic properties of close-spaced dangling-bond (DB) pairs in a hydrogen-passivated Si(001):H p-doped surface. Two types of DB pairs are considered, called "cross" and "line" structures. Our scanning tunneling spectroscopy (STS) data show that, althou...

journal_title：Scientific reports

authors： Engelund M,Zuzak R,Godlewski S,Kolmer M,Frederiksen T,García-Lekue A,Sánchez-Portal D,Szymonski M

更新日期：2015-09-25 00:00:00

abstract：:In addition to its role in sister chromatid cohesion, genome stability and integrity, the cohesin complex is involved in gene transcription. Mutations in core cohesin subunits SMC1A, SMC3 and RAD21, or their regulators NIPBL and HDAC8, cause Cornelia de Lange syndrome (CdLS). Recent evidence reveals that gene expressi...

journal_title：Scientific reports

authors： Mannini L,C Lamaze F,Cucco F,Amato C,Quarantotti V,Rizzo IM,Krantz ID,Bilodeau S,Musio A

更新日期：2015-11-19 00:00:00

abstract：:Ocular graft-versus-host disease (GVHD) is a common complication after hematopoietic stem cell transplantation (HSCT). Here we compared the diagnostic rates of ocular GVHD, including its severity, prognosis and the agreement, obtained using three grading scales: the National Institutes of Health (NIH) eye score, Japan...

journal_title：Scientific reports

authors： Tatematsu Y,Ogawa Y,Abe T,Kamoi M,Uchino M,Saijo-Ban Y,Yaguchi S,Mukai S,Mori T,Okamoto S,Tsubota K

更新日期：2014-10-22 00:00:00

abstract：:In this prospective pilot study, we aimed to evaluate the ability of cardiac magnetic resonance imaging (CMR) parameters of right ventricular function and pulmonary artery stiffness to identify pulmonary hypertension (PH), predict major adverse cardiovascular events (MACEs) in patients with secondary PH due to chronic...

journal_title：Scientific reports

authors： Agoston-Coldea L,Lupu S,Mocan T

更新日期：2018-09-27 00:00:00

abstract：:Identifying early-warning signals of a critical transition for a complex system is difficult, especially when the target system is constantly perturbed by big noise, which makes the traditional methods fail due to the strong fluctuations of the observed data. In this work, we show that the critical transition is not t...

journal_title：Scientific reports

authors： Liu R,Chen P,Aihara K,Chen L

更新日期：2015-12-09 00:00:00

abstract：:Enzymes that cleave polysaccharides in lignocellulose, i. e., cellulases, xylanases, and accessory enzymes, play crucial roles in the natural decomposition of plant-derived biomass and its efficient and sustainable processing into biofuels or other bulk chemicals. The analysis of open reading frame cthe_2195 from the ...

journal_title：Scientific reports

authors： Heinze S,Mechelke M,Kornberger P,Liebl W,Schwarz WH,Zverlov VV

更新日期：2017-09-11 00:00:00

abstract：:A new ether-based electrolyte to match lithium metal electrode is prepared by introducing 1, 4-dioxane as co-solvent into lithium bis(fluorosulfonyl)imide/1,2-dimethoxyethane solution. Under the synergetic effect of solvents and salt, this simple liquid electrolyte presents stable Li cycling with dendrite-free Li depo...

journal_title：Scientific reports

authors： Miao R,Yang J,Xu Z,Wang J,Nuli Y,Sun L

更新日期：2016-02-16 00:00:00

abstract：:The Na+/H+ exchanger-1 (NHE1) supports tumour growth, making NHE1 inhibitors of interest in anticancer therapy, yet their molecular effects are incompletely characterized. Here, we demonstrate that widely used pyrazinoylguanidine-type NHE1 inhibitors potently inhibit growth and survival of cancer cell spheroids, in a ...

journal_title：Scientific reports

authors： Rolver MG,Elingaard-Larsen LO,Andersen AP,Counillon L,Pedersen SF

更新日期：2020-04-02 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) and placental growth factor (PlGF) plays a crucial role in breakdown of the blood-retinal barrier due to hyperpermeability in diabetic retinopathy (DR). However, the distinct signaling driven by VEGF and PlGF in the pathogenesis of DR remains unclear. In this study, we investi...

journal_title：Scientific reports

authors： Jiao W,Ji JF,Xu W,Bu W,Zheng Y,Ma A,Zhao B,Fan Q

更新日期：2019-10-25 00:00:00

abstract：:In the Brown et al. study 'Increased food supply mitigates ocean acidification effects on calcification but exacerbates effects on growth' they show disagreement with the tested hypothesis and data analysis methodology used in our 2016 study. We acknowledge careful criticism and a constructive dialogue are necessary t...

journal_title：Scientific reports

authors： Ramajo L,Hendriks IE,Lagos NA,Krause-Jensen D,Marbà N,Sejr MK,Duarte CM

更新日期：2018-06-28 00:00:00

abstract：:Supplementation of cattle diets with n-3-polyunsaturated fatty acids (PUFA) can improve reproductive efficiency. Conversely, short-term fluctuations in feed supply can impact pregnancy establishment. The objectives of this study were to examine the effects of (1) dietary supplementation with n-3-PUFA and (2) post-inse...

journal_title：Scientific reports

authors： Surlis C,Cormican P,Waters SM,Lonergan P,Keogh K,Doyle DN,Kenny DA

更新日期：2020-11-27 00:00:00

abstract：:Increased filaggrin expression was found to be correlated with severity scores in chronic spontaneous urticaria (CSU); however, the role of filaggrin breakdown products (FBPs) in CSU has not been studied. We collected stratum corneum (SC) specimens from the volar forearms of 10 CSU patients, 10 AD patients, and 10 hea...

journal_title：Scientific reports

authors： Pham DL,Lim KM,Joo KM,Park HS,Leung DYM,Ye YM

更新日期：2017-05-02 00:00:00

abstract：:We characterised wool traits, and skin gene expression profiles of fine wool Super Merino (SM) and coarse wool Small Tail Han (STH) sheep. SM sheep had a significantly higher total density of wool follicles, heavier fleeces, finer fibre diameter, and increased crimp frequency, staple length and wool grease (lanolin) p...

journal_title：Scientific reports

authors： Zhang L,Sun F,Jin H,Dalrymple BP,Cao Y,Wei T,Vuocolo T,Zhang M,Piao Q,Ingham AB

更新日期：2017-10-30 00:00:00

abstract：:Fusarium head blight (FHB) is a devastating disease of wheat worldwide. Fhb1 is the most consistently reported quantitative trait locus (QTL) for FHB resistance breeding. A pore-forming toxin-like (PFT) gene at Fhb1 was first cloned by map-based cloning and found to confer FHB resistance in wheat. Proteins often inter...

journal_title：Scientific reports

authors： He Y,Wu L,Liu X,Zhang X,Jiang P,Ma H

更新日期：2019-10-29 00:00:00

abstract：:The secretome complexity and lignocellulose degrading capacity of Pleurotus ostreatus monokaryons mkPC9 and mkPC15 and mated dikaryon dkN001 were studied in submerged liquid cultures containing wood, glucose, and wood plus glucose as carbon sources. The study revealed that this white-rot basidiomycete attacks all the ...

journal_title：Scientific reports

authors： Alfaro M,Majcherczyk A,Kües U,Ramírez L,Pisabarro AG

更新日期：2020-07-24 00:00:00

abstract：:Biofilms are complex microbial communities that present serious contamination risks to our environment and health. In this study, atmospheric air plasma and airborne acoustic ultrasound technology were applied to inactivate Escherichia coli and Listeria innocua biofilms. Both technologies were efficient in controlling...

journal_title：Scientific reports

authors： Patange AD,Simpson JC,Curtin JF,Burgess CM,Cullen PJ,Tiwari BK

更新日期：2021-01-27 00:00:00

abstract：:Ulvan, which is one of the major structural polysaccharides of the cell walls of green macroalgae, is degraded by ulvan lyases via the β-elimination mechanism with the release of oligosaccharides that have unsaturated 4-deoxy-L-threo-hex-4-enopyranosiduronic acid (∆) at the non-reducing end. These ulvan lyases belong ...

journal_title：Scientific reports

authors： Konasani VR,Jin C,Karlsson NG,Albers E

更新日期：2018-10-02 00:00:00

abstract：:We assessed the Chinese version of the Drug Abuse Screening Test (DAST-10) for identifying illicit drug use during pregnancy among Chinese population. Chinese pregnant women attending their first antenatal visit or their first unbooked visit to the maternity ward were recruited during a 4-month study period in 2011. T...

journal_title：Scientific reports

authors： Lam LP,Leung WC,Ip P,Chow CB,Chan MF,Ng JW,Sing C,Lam YH,Mak WL,Chow KM,Chin RK

更新日期：2015-06-19 00:00:00

abstract：:Landscape's spatial structure has vast implications for the dynamics and distribution of species populations and ecological communities. However, the characterization of the structure of spatial networks has not received nearly as much attention as networks of species interactions counterparts. Recent experiments show...

journal_title：Scientific reports

authors： Gilarranz LJ

更新日期：2020-05-26 00:00:00

abstract：:Recently, electromagnetic (EM) waves carrying orbital angular momentum (OAM) has received considerable attention in increasingly many different realms, such as communication systems, super-resolution imaging, optical communications and quantum state manipulation. In this paper, two different kinds of two dimensional (...

journal_title：Scientific reports

authors： Oraizi H,Emamian H

更新日期：2020-04-30 00:00:00

abstract：:Acquisition of the lower jaw (mandible) was evolutionarily important for jawed vertebrates. In humans, syndromic craniofacial malformations often accompany jaw anomalies. The basic helix-loop-helix transcription factor Hand2, which is conserved among jawed vertebrates, is expressed in the neural crest in the mandibula...

journal_title：Scientific reports

authors： Funato N,Kokubo H,Nakamura M,Yanagisawa H,Saga Y

更新日期：2016-06-22 00:00:00

abstract：:Several studies have investigated the association between polymorphisms in protamine 1 and 2 genes and male infertility risk, with inconsistent results to date. This meta-analysis based on the 13 published case-control studies, including 7350 cases and 6167 controls, was performed to further establish the potential as...

journal_title：Scientific reports

authors： Jiang W,Sun H,Zhang J,Zhou Q,Wu Q,Li T,Zhang C,Li W,Zhang M,Xia X

更新日期：2015-10-16 00:00:00

abstract：:MADS-box transcription factors widely regulate all aspects of plant growth including development and reproduction. Although the MADS-box gene family genes have been extensively characterized in many plants, they have not been studied in closely related species. In this study, 73 and 74 MADS-box genes were identified i...

journal_title：Scientific reports

authors： Meng D,Cao Y,Chen T,Abdullah M,Jin Q,Fan H,Lin Y,Cai Y

更新日期：2019-02-04 00:00:00

abstract：:The oxidative stress regulator Spx is ubiquitously found among Gram-positive bacteria. Previously, we reported identification of two Spx proteins in Streptococcus mutans - SpxA1 was the primary activator of oxidative stress genes whereas SpxA2 served a backup role. Here, we used RNA sequencing to uncover the scope of ...

journal_title：Scientific reports

authors： Kajfasz JK,Ganguly T,Hardin EL,Abranches J,Lemos JA

更新日期：2017-11-22 00:00:00