Distinct downstream signaling and the roles of VEGF and PlGF in high glucose-mediated injuries of human retinal endothelial cells in culture.

abstract：:We aimed to assess the role of computerized tomography attenuation values (Hounsfield unit-HU) for differentiating pyonephrosis from hydronephrosis and for predicting postoperative infectious complications in patients with obstructive uropathy. We analysed data from 122 patients who underwent nephrostomy tube or urete...

journal_title：Scientific reports

authors： Boeri L,Fulgheri I,Palmisano F,Lievore E,Lorusso V,Ripa F,D'Amico M,Spinelli MG,Salonia A,Carrafiello G,Montanari E

更新日期：2020-10-29 00:00:00

abstract：:Muscle wasting and atrophy are regulated by multiple molecular processes, including mRNA processing. Reduced levels of the polyadenylation binding protein nucleus 1 (PABPN1), a multifactorial regulator of mRNA processing, cause muscle atrophy. A proteomic study in muscles with reduced PABPN1 levels suggested dysregula...

journal_title：Scientific reports

authors： Olie CS,van der Wal E,Domagoj C,Maton L,de Greef JC,Lin IH,Chen YF,Kareem E,Penninger JM,Kessler BM,Raz V

更新日期：2020-10-19 00:00:00

abstract：:Although chronic kidney disease (CKD) is associated with functional decline, whether proteinuria alone is associated with functional statuses over the course of acute illnesses independent of CKD is unclear. During 2014, we prospectively enrolled non-dialysis patients aged ≥65 years, and all participants underwent spo...

journal_title：Scientific reports

authors： Chao CT,Tsai HB,Chiang CK,Huang JW,Hung KY

更新日期：2017-02-08 00:00:00

abstract：:A photovoltaic reactor was designed for artificial photosynthesis, based on the reactions involved in high energy hydrogen atoms, which were produced from water electrolysis. Water and CO2, under the conditions studied, were converted to oxalate (H2C2O4) and a polymer. This was the first time that the oxalates and oxa...

journal_title：Scientific reports

authors： Nong G,Chen S,Xu Y,Huang L,Zou Q,Li S,Mo H,Zhu P,Cen W,Wang S

更新日期：2014-01-06 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Jacquemond I,Muggeo A,Lamblin G,Tristan A,Gillet Y,Bolze PA,Bes M,Gustave CA,Rasigade JP,Golfier F,Ferry T,Dubost A,Abrouk D,Barreto S,Prigent-Combaret C,Thioulouse J,Lina G,Muller D

更新日期：2020-01-30 00:00:00

abstract：:A new approach to estimate the Shannon entropy of a long-range correlated sequence is proposed. The entropy is written as the sum of two terms corresponding respectively to power-law (ordered) and exponentially (disordered) distributed blocks (clusters). The approach is illustrated on the 24 human chromosome sequences...

journal_title：Scientific reports

authors： Carbone A

更新日期：2013-01-01 00:00:00

abstract：:Cold Syndrome and Hot Syndrome are thousand-year-old key therapeutic concepts in traditional Chinese medicine (TCM), which depict the loss of body homeostasis. However, the scientific basis of TCM Syndrome remains unclear due to limitations of current reductionist approaches. Here, we established a network balance mod...

journal_title：Scientific reports

authors： Li R,Ma T,Gu J,Liang X,Li S

更新日期：2013-01-01 00:00:00

abstract：:The search for green and sustainable modification method to produce durable bamboo materials remains a challenge in industry. Here, heat treatment in tung oil at 100-200 °C was employed to modify bamboo materials. Oil permeation and distribution in the structure of bamboo samples during heat treatment were explored. T...

journal_title：Scientific reports

authors： Tang T,Zhang B,Liu X,Wang W,Chen X,Fei B

更新日期：2019-09-06 00:00:00

abstract：:Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins) have been shown to overcome tyrosine kinase inhibitor (TKI) resistance in epithelial growth factor receptor (EGFR) mutated non-small cell lung cancer (NSCLC) cells in vivo and in vitro. However, little is known about the putative induction of no...

journal_title：Scientific reports

authors： Otahal A,Aydemir D,Tomasich E,Minichsdorfer C

更新日期：2020-01-22 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Cencetti G,Clusella P,Fanelli D

更新日期：2020-02-18 00:00:00

abstract：:Social immunity forms an essential part of the defence repertoire of social insects. In response to infestation by the parasitic mite Varroa destructor and its associated viruses, honey bees (Apis mellifera L.) have developed a specific behaviour (varroa-sensitive hygiene, or VSH) that helps protect the colony from th...

journal_title：Scientific reports

authors： Mondet F,Kim SH,de Miranda JR,Beslay D,Le Conte Y,Mercer AR

更新日期：2016-05-03 00:00:00

abstract：:Primary dysmenorrhea (PDM) is the most prevalent gynecological problem. Many key brain systems are engaged in pain processing. In light of dynamic communication within and between systems (or networks) in shaping pain experience and behavior, the intra-regional functional connectivity (FC) in the hub regions of the sy...

journal_title：Scientific reports

authors： Wu TH,Tu CH,Chao HT,Li WC,Low I,Chuang CY,Yeh TC,Cheng CM,Chou CC,Chen LF,Hsieh JC

更新日期：2016-04-19 00:00:00

abstract：:Age of complementary foods introduction is associated with childhood anemia, but the ideal age for the introduction of complementary foods to infants is a continuing topic of debate. We examined the longitudinal association between complementary foods introduction age and risk of anemia in 18,446 children from the Jia...

journal_title：Scientific reports

authors： Wang F,Liu H,Wan Y,Li J,Chen Y,Zheng J,Huang T,Li D

更新日期：2017-03-23 00:00:00

abstract：:MCR-1 is a phosphoethanolamine (pEtN) transferase that modifies the pEtN moiety of lipid A, conferring resistance to colistin, which is an antibiotic belonging to the class of polypeptide antibiotics known as polymyxins and is the last-line antibiotic used to treat multidrug resistant bacterial infections. Here we det...

journal_title：Scientific reports

authors： Hu M,Guo J,Cheng Q,Yang Z,Chan EWC,Chen S,Hao Q

更新日期：2016-12-13 00:00:00

abstract：:Zeolites/molecular sieves with uniform, molecular-sized pores are important for many adsorption-based separation processes. Pore size gaps, however, exist in the current zeolite family. This leads to a great challenge of separating molecules with size differences at ~0.01 nm level. Here, we report a novel concept, por...

journal_title：Scientific reports

authors： Song Z,Huang Y,Xu WL,Wang L,Bao Y,Li S,Yu M

更新日期：2015-09-11 00:00:00

abstract：:Reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR) is an accurate and fast method to measure gene expression. Reproducibility of the analyses is the main limitation of RT-qPCR experiments. Galaxy is an open, web-based, genomic workbench for a reproducible, transparent, and accessible scie...

journal_title：Scientific reports

authors： Zanardi N,Morini M,Tangaro MA,Zambelli F,Bosco MC,Varesio L,Eva A,Cangelosi D

更新日期：2019-11-26 00:00:00

abstract：:MicroRNAs (miRNAs) have been reported to be involved in DNA damage response induced by ionizing radiation (IR). c-Myc is reduced when cells treated with IR or other DNA damaging agents. It is unknown whether miRNAs participate in c-Myc downregulation in response to IR. In the present study, we found that miR-449a enha...

journal_title：Scientific reports

authors： Mao A,Zhao Q,Zhou X,Sun C,Si J,Zhou R,Gan L,Zhang H

更新日期：2016-06-02 00:00:00

abstract：:In this work, we utilise a combination of theory, computation and experiments to understand the early events related to the nucleation of Ag filaments on α-Ag2WO4 crystals, which is driven by an accelerated electron beam from an electron microscope under high vacuum. The growth process and the chemical composition and...

journal_title：Scientific reports

authors： Andrés J,Gracia L,Gonzalez-Navarrete P,Longo VM,Avansi W Jr,Volanti DP,Ferrer MM,Lemos PS,La Porta FA,Hernandes AC,Longo E

更新日期：2014-06-23 00:00:00

abstract：:Biocompatible surfaces hold key to a variety of biomedical problems that are directly related to the competition between host-tissue cell integration and bacterial colonisation. A saving solution to this is seen in the ability of cells to uniquely respond to physical cues on such surfaces thus prompting the search for...

journal_title：Scientific reports

authors： Diu T,Faruqui N,Sjöström T,Lamarre B,Jenkinson HF,Su B,Ryadnov MG

更新日期：2014-11-20 00:00:00

abstract：:We study an Ising chain undergoing a quantum phase transition in a quantum magnetic field. Such a field can be emulated by coupling the chain to a central spin initially in a superposition state. We show that--by adiabatically driving such a system--one can prepare a quantum superposition of any two ground states of t...

journal_title：Scientific reports

authors： Rams MM,Zwolak M,Damski B

更新日期：2012-01-01 00:00:00

abstract：:This paper investigates the possibility of saving a network that is predicted to have a cascading failure that will eventually lead to a total collapse. We model cascading failures using the recently proposed KQ model. Then predict an impending total collapse by monitoring critical slowing down indicators and subseque...

journal_title：Scientific reports

authors： Zhou D,Elmokashfi A

更新日期：2018-05-10 00:00:00

abstract：:Centromeres usually contain large amounts of tandem repeat DNA. Alpha satellite DNA (AS) is the most abundant tandem repeat DNA found in the centromeres of simian primates. The AS of humans contains sequences organized into higher-order repeat (HOR) structures, which are tandem arrays of larger repeat units consisting...

journal_title：Scientific reports

authors： Sujiwattanarat P,Thapana W,Srikulnath K,Hirai Y,Hirai H,Koga A

更新日期：2015-05-14 00:00:00

abstract：:A new approach for achieving two - dimensional (2D) atom localization microscopy based on the projection of three - dimensional (3D) localization in the plane of the detector is described in the present work. Spatial variation of the position-dependent 2D-localization pattern in the xy-plane is obtained with the shift...

journal_title：Scientific reports

authors： Dutta BK,Panchadhyayee P,Bayal I,Das N,Mahapatra PK

更新日期：2020-01-17 00:00:00

abstract：:The preparation of mesoporous iron oxides with controllable physiochemical properties for effective therapeutic drug delivery remains a formidable challenge. Herein, iron oxide mesoporous magnetic microparticles (IO-MMMs) were prepared by a modified reverse hard-templating approach using, for the first time, acid-prep...

journal_title：Scientific reports

authors： El-Boubbou K,Ali R,Al-Zahrani H,Trivilegio T,Alanazi AH,Khan AL,Boudjelal M,AlKushi A

更新日期：2019-07-01 00:00:00

abstract：:In this study, a novel resorufin thionocarbonate-based Hg2+-selective signaling probe (RT) for microfluidic paper-based analytical device (μPAD) applications is reported. The designed probe, RT, was readily synthesized by the one-step reaction of resorufin with phenyl thionochloroformate. The RT probe displayed a prom...

journal_title：Scientific reports

authors： Choi MG,Park SY,Park KY,Chang SK

更新日期：2019-03-04 00:00:00

abstract：:The identification of genome-wide selection signatures can provide insights on the mechanisms of natural and/or artificial selection and uncover genes related to biological functions and/or phenotypes. Tibetan sheep are an important livestock in Tibet, providing meat and wool for Tibetans who are renown for breeding l...

journal_title：Scientific reports

authors： Zhang Y,Xue X,Liu Y,Abied A,Ding Y,Zhao S,Wang W,Ma L,Guo J,Guan W,Pu Y,Mwacharo JM,Han J,Ma Y,Zhao Q

更新日期：2021-01-28 00:00:00

abstract：:Ice-albedo feedback due to the albedo contrast between water and ice is a major factor in seasonal sea ice retreat, and has received increasing attention with the Arctic Ocean shifting to a seasonal ice cover. However, quantitative evaluation of such feedbacks is still insufficient. Here we provide quantitative eviden...

journal_title：Scientific reports

authors： Kashiwase H,Ohshima KI,Nihashi S,Eicken H

更新日期：2017-08-15 00:00:00

abstract：:The bald eagle (Haliaeetus leucocephalus) once experienced near-extinction but has since rebounded. For decades, bald eagles near the Wisconsin River, USA, have experienced a lethal syndrome with characteristic clinical and pathological features but unknown etiology. Here, we describe a novel hepacivirus-like virus (F...

journal_title：Scientific reports

authors： Goldberg TL,Sibley SD,Pinkerton ME,Dunn CD,Long LJ,White LC,Strom SM

更新日期：2019-10-18 00:00:00

abstract：:Non-response to intravitreal ranibizumab represents a frequent problem in pachychoroid neovasculopathy (PNV). To investigate the effectivity of switching to aflibercept, the database of the Ludwig Maximilians University, Munich, was screened for patients fulfilling the following inclusion criteria: (i) diagnosis of PN...

journal_title：Scientific reports

authors： Schworm B,Luft N,Keidel LF,Herold TR,Wolf A,Priglinger SG,Siedlecki J

更新日期：2020-05-21 00:00:00

abstract：:The ability to predict the magnitude of an earthquake caused by deep fluid injections is an important factor for assessing the safety of the reservoir storage and the seismic hazard. Here, we propose a new approach to evaluate the seismic energy released during fluid injection by integrating injection parameters, indu...

journal_title：Scientific reports

authors： De Barros L,Cappa F,Guglielmi Y,Duboeuf L,Grasso JR

更新日期：2019-03-21 00:00:00