Abstract：
:Social immunity forms an essential part of the defence repertoire of social insects. In response to infestation by the parasitic mite Varroa destructor and its associated viruses, honey bees (Apis mellifera L.) have developed a specific behaviour (varroa-sensitive hygiene, or VSH) that helps protect the colony from this parasite. Brood cells heavily infested with mites are uncapped, the brood killed, and the cell contents removed. For this extreme sacrifice to be beneficial to the colony, the targeting of parasitized brood for removal must be accurate and selective. Here we show that varroa-infested brood produce uniquely identifiable cues that could be used by VSH-performing bees to identify with high specificity which brood cells to sacrifice. This selective elimination of mite-infested brood is a disease resistance strategy analogous to programmed cell death, where young bees likely to be highly dysfunctional as adults are sacrificed for the greater good of the colony.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Mondet F,Kim SH,de Miranda JR,Beslay D,Le Conte Y,Mercer ARdoi
10.1038/srep25444subject
Has Abstractpub_date
2016-05-03 00:00:00pages
25444issn
2045-2322pii
srep25444journal_volume
6pub_type
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