Mutant cohesin affects RNA polymerase II regulation in Cornelia de Lange syndrome.

abstract：:The symmetrically stable craniofacial bony structure supports the complex functions and delicate contour of the face. Congenital craniofacial deformities are often accompanied by bony defects and have been repetitively correlated with compromised dento-maxillary stability, but neither the extent nor the pattern of cle...

journal_title：Scientific reports

authors： Luo X,Huang H,Yin X,Shi B,Li J

更新日期：2019-03-12 00:00:00

abstract：:We discuss a scheme to retrieve transient conformational molecular structure information using photoelectron angular distributions (PADs) that have averaged over partial alignments of isolated molecules. The photoelectron is pulled out from a localized inner-shell molecular orbital by an X-ray photon. We show that a t...

journal_title：Scientific reports

authors： Wang X,Le AT,Yu C,Lucchese RR,Lin CD

更新日期：2016-03-30 00:00:00

abstract：:Assessment of colonic motor dysfunction is rarely done because of inadequate methodology and lack of knowledge about normal motor patterns. Here we report on elucidation of intraluminal pressure patterns using High Resolution Colonic Manometry during a baseline period and in response to a meal, in 15 patients with con...

journal_title：Scientific reports

authors： Chen JH,Yu Y,Yang Z,Yu WZ,Chen WL,Yu H,Kim MJ,Huang M,Tan S,Luo H,Chen J,Chen JD,Huizinga JD

更新日期：2017-02-20 00:00:00

abstract：:Using high resolution powder x-ray and neutron diffraction experiments, we determined the off-centered displacement of the ions within a unit cell and magnetoelectric coupling in nanoscale BiFeO3 (≈20-200 nm). We found that both the off-centered displacement of the ions and magnetoelectric coupling exhibit nonmonotoni...

journal_title：Scientific reports

authors： Goswami S,Bhattacharya D,Ghosh CK,Ghosh B,Kaushik SD,Siruguri V,Krishna PSR

更新日期：2018-02-27 00:00:00

abstract：:The unfolded protein response (UPR) not only resolves endoplasmic reticulum (ER) stress, but also regulates cellular physiological functions. In this study, we first linked the UPR to the physiological roles of brown adipose tissue (BAT). BAT is one of the tissues that control energy homeostasis in the body. Brown adi...

journal_title：Scientific reports

authors： Asada R,Kanemoto S,Matsuhisa K,Hino K,Cui M,Cui X,Kaneko M,Imaizumi K

更新日期：2015-11-16 00:00:00

abstract：:Although copy number variation (CNV) and presence-absence variation (PAV) have been discovered in selected gene families in most crop species, the global prevalence of these polymorphisms in most complex genomes is still unclear and their influence on quantitatively inherited agronomic traits is still largely unknown....

journal_title：Scientific reports

authors： Gabur I,Chawla HS,Lopisso DT,von Tiedemann A,Snowdon RJ,Obermeier C

更新日期：2020-03-05 00:00:00

abstract：:Chitin is a valuable peat substrate amendment by increasing lettuce growth and reducing the survival of the zoonotic pathogen Salmonella enterica on lettuce leaves. The production of chitin-catabolic enzymes (chitinases) play a crucial role and are mediated through the microbial community. A higher abundance of plant-...

journal_title：Scientific reports

authors： De Tender C,Mesuere B,Van der Jeugt F,Haegeman A,Ruttink T,Vandecasteele B,Dawyndt P,Debode J,Kuramae EE

更新日期：2019-07-09 00:00:00

abstract：:Sensitivity of the anatase and rutile phases of titanium dioxide to Swift Heavy Ion (SHI) irradiation was experimentally probed and compared with the predictions of the Coulomb explosion, analytical and inelastic thermal spike models of ion-matter interaction. Conforming to the predictions of all these models, our stu...

journal_title：Scientific reports

authors： Rath H,Dash BN,Benyagoub A,Mishra NC

更新日期：2018-08-06 00:00:00

abstract：:Here, we report results on systematic analysis of DNA substrate preferences of three N6-adenine β-class DNA methyltransferases that are part of the type II restriction-modification systems. The studied enzymes were: M.EcoVIII, M.HindIII and M.LlaCI, which although found in phylogenetically distant bacteria (γ-proteoba...

journal_title：Scientific reports

authors： Wons E,Mruk I,Kaczorowski T

更新日期：2018-05-29 00:00:00

abstract：:Breast cancer is the most common cancer in women. However, it remains unproven whether psychological factors have an influence on breast cancer incidence. In our earlier study, subjects possessing two personality traits, decisiveness and "ikigai" (a Japanese word meaning something that makes one's life worth living), ...

journal_title：Scientific reports

authors： Sawada T,Nishiyama T,Kikuchi N,Wang C,Lin Y,Mori M,Tanno K,Tamakoshi A,Kikuchi S

更新日期：2016-09-02 00:00:00

abstract：:Solving the crystal structure of Cbl(TKB) in complex with a pentapeptide, pYTPEP, revealed that the PEP region adopted a poly-L-proline type II (PPII) helix. An unnatural amino acid termed a proline-templated glutamic acid (ptE) that constrained both the backbone and sidechain to the bound conformation was synthesized...

journal_title：Scientific reports

authors： Kumar EA,Chen Q,Kizhake S,Kolar C,Kang M,Chang CE,Borgstahl GE,Natarajan A

更新日期：2013-01-01 00:00:00

abstract：:The human brain has evolved specialised mechanisms to enable the rapid detection of threat cues, including emotional face expressions (e.g., fear and anger). However, contextual cues - such as gaze direction - influence the ability to recognise emotional expressions. For instance, anger paired with direct gaze, and fe...

journal_title：Scientific reports

authors： Caruana N,Inkley C,Zein ME,Seymour K

更新日期：2019-11-07 00:00:00

abstract：:We present results from first-principles calculations on silane (SiH4) under pressure. We find that a three dimensional P-3 structure becomes the most stable phase above 241 GPa. A prominent structural feature, which separates the P-3 structure from previously observed/predicted SiH4 structures, is that a fraction of ...

journal_title：Scientific reports

authors： Cui W,Shi J,Liu H,Yao Y,Wang H,Iitaka T,Ma Y

更新日期：2015-08-12 00:00:00

abstract：:Herbs may contain pesticide residues which are an important discriminator of food security and food quality. The challenge of the research was to assess the fate of the herbicide clethodim (CLE) and the insecticide spirotetramat (SPI) applied in herbs (BBCH 11-21) during herb growth and processing under controlled gre...

journal_title：Scientific reports

authors： Jankowska M,Kaczyński P,Łozowicka B

更新日期：2020-01-28 00:00:00

abstract：:Global aquaculture makes an important contribution to food security directly (by increasing food availability and accessibility) and indirectly (as a driver of economic development). In order to enable sustainable expansion of aquaculture, we need to understand aquaculture's contribution to global greenhouse gas (GHG)...

journal_title：Scientific reports

authors： MacLeod MJ,Hasan MR,Robb DHF,Mamun-Ur-Rashid M

更新日期：2020-07-15 00:00:00

abstract：:We investigate temperature smearing effects on the electron-boson spectral density function (I(2)χ(ω)) obtained from optical data using a maximum entropy inversion method. We start with two simple model input I(2)χ(ω), calculate the optical scattering rates at selected temperatures using the model input spectral densi...

journal_title：Scientific reports

authors： Hwang J

更新日期：2016-03-31 00:00:00

abstract：:The focus of this study is to evaluate the efficacy of Machine Learning (ML) algorithms in the long-lead prediction of El Niño (La Niña) Modoki (ENSO Modoki) index (EMI). We evaluated two widely used non-linear ML algorithms namely Support Vector Regression (SVR) and Random Forest (RF) to forecast the EMI at various l...

journal_title：Scientific reports

authors： Pal M,Maity R,Ratnam JV,Nonaka M,Behera SK

更新日期：2020-01-15 00:00:00

abstract：:The analysis of questionnaires often involves representing the high-dimensional responses in a low-dimensional space (e.g., PCA, MCA, or t-SNE). However questionnaire data often contains categorical variables and common statistical model assumptions rarely hold. Here we present a non-parametric approach based on Fishe...

journal_title：Scientific reports

authors： Har-Shemesh O,Quax R,Lansing JS,Sloot PMA

更新日期：2020-05-25 00:00:00

abstract：:The parasitic nematode Trichuris trichiura is a significant burden on public health in developing countries, and currently available drugs exhibit a poor cure rate. Worms live within a specialised tunnel of host intestinal epithelial cells and have anterior-ventral projections of the cuticle termed "cuticular inflatio...

journal_title：Scientific reports

authors： O'Sullivan JDB,Cruickshank SM,Starborg T,Withers PJ,Else KJ

更新日期：2020-04-03 00:00:00

abstract：:Hesperiidae is one of the largest families of butterflies. Our knowledge of the higher systematics on hesperiids from China is still very limited. We infer the phylogenetic relationships of the subfamilies of Chinese skippers based on three mitochondrial genes (cytochrome b (Cytb), the NADH dehydrogenase subunit 1 (ND...

journal_title：Scientific reports

authors： Yuan X,Gao K,Yuan F,Wang P,Zhang Y

更新日期：2015-06-10 00:00:00

abstract：:Coherent Anti-Stokes Raman Spectroscopy (CARS) is performed on single spores (conidia) of the fungus Aspergillus nidulans in order to establish a baseline measurement for fungal spores. Chemical maps of single spores are generated and spectral differentiation between the cell wall and the cytoplasm is achieved. Princi...

journal_title：Scientific reports

authors： D Strycker B,Han Z,Commer B,D Shaw B,V Sokolov A,O Scully M

更新日期：2019-02-11 00:00:00

abstract：:Nanothermometry methods with intracellular sensitivities have the potential to make important contributions to fundamental cell biology and medical fields, as temperature is a relevant physical parameter for molecular reactions to occur inside the cells and changes of local temperature are well identified therapeutic ...

journal_title：Scientific reports

authors： Savchuk OA,Silvestre OF,Adão RMR,Nieder JB

更新日期：2019-05-17 00:00:00

abstract：:We study semiconductor hyperbolic metamaterials (SHMs) at the quantum limit experimentally using spectroscopic ellipsometry as well as theoretically using a new microscopic theory. The theory is a combination of microscopic density matrix approach for the material response and Green's function approach for the propaga...

journal_title：Scientific reports

authors： Montaño I,Campione S,Klem JF,Beechem TE,Wolf O,Sinclair MB,Luk TS

更新日期：2018-11-12 00:00:00

abstract：:Quartz is a common phase in high-silica igneous rocks and is resistant to post-eruptive alteration, thus offering a reliable record of magmatic processes in silicic magma systems. Here we employ the 75 ka Toba super-eruption as a case study to show that quartz can resolve late-stage temporal changes in magmatic δ18O v...

journal_title：Scientific reports

authors： Budd DA,Troll VR,Deegan FM,Jolis EM,Smith VC,Whitehouse MJ,Harris C,Freda C,Hilton DR,Halldórsson SA,Bindeman IN

更新日期：2017-01-25 00:00:00

abstract：:Embryonic Stem Cells (ESCs) are expected to show a stable euploid karyotype, but in the last decade (sub)chromosomal aberrations have been systematically described in these cell lines when maintained in vitro. Culture conditions and long-term culture have been traditionally proposed as possible factors involved in the...

journal_title：Scientific reports

authors： Gaztelumendi N,Nogués C

更新日期：2014-06-17 00:00:00

abstract：:Existing understanding of molecular composition of sputum and its role in tuberculosis patients is variously limited to its diagnostic potential. We sought to identify infection induced sputum proteome alteration in active/non tuberculosis patients (A/NTB) and their role in altered lung patho-physiology. Out of the st...

journal_title：Scientific reports

authors： Bishwal SC,Das MK,Badireddy VK,Dabral D,Das A,Mahapatra AR,Sahu S,Malakar D,Singh II,Mazumdar H,Patgiri SJ,Deka T,Kapfo W,Liegise K,Kupa RU,Debnath S,Bhowmik R,Debnath R,Behera RK,Pillai MG,Deuri P,Nath R,Khal

更新日期：2019-01-31 00:00:00

abstract：:This study investigated the glucono-δ-lactone (GDL)-induced aggregation of isoflavones and soy proteins in soymilk. High-performance liquid chromatography (HPLC) analysis indicated that isoflavones mixed with β-conglycinin (7S) and glycinin (11S) proteins formed 7S-isoflavone and 11S-isoflavone complexes in soymilk su...

journal_title：Scientific reports

authors： Hsia SY,Hsiao YH,Li WT,Hsieh JF

更新日期：2016-10-20 00:00:00

abstract：:Nanoporous electrodes have received great attention because of their unique electrochemical properties. Here, the electrocatalytic oxygen evolution reaction (OER) activities at porous Pt layers with pore dimensions in the microporous range were examined. The OER activity of the porous Pt layers in acidic media increas...

journal_title：Scientific reports

authors： Lim T,Sung M,Kim J

更新日期：2017-11-13 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Ravanbakhsh H,Bao G,Mongeau L

更新日期：2020-03-24 00:00:00

abstract：:Nanophotonic circuitry requires an ability to externally control and analyze optical signals tightly confined in subwavelength volumes. Various schemes of surface plasmon (SP) routing have been presented using active and passive metasurfaces. One of the most appealing approaches is the use of plasmonic spin-orbit inte...

journal_title：Scientific reports

authors： Revah M,Yaroshevsky A,Gorodetski Y

更新日期：2019-06-20 00:00:00