Profiling of differentially expressed microRNAs in arrhythmogenic right ventricular cardiomyopathy.

abstract：:Drug resistance is a major issue in the treatment of glioblastoma. Almost all glioblastomas are intrinsically resistant to chemotherapeutic temozolomide (TMZ) or develop resistance during treatment. The interaction networks of microRNAs (miRNAs) and mRNAs likely regulate most biological processes and can be employed t...

journal_title：Scientific reports

authors： Hiddingh L,Raktoe RS,Jeuken J,Hulleman E,Noske DP,Kaspers GJ,Vandertop WP,Wesseling P,Wurdinger T

更新日期：2014-06-11 00:00:00

abstract：:The estrogen signaling pathway has been reported to modulate prostate cancer (PCa) progression through the activity of estrogen receptors α and β (ERα and ERβ). Given that selective estrogen receptor modulators (SERMs) are used to treat breast cancer, ERs have been proposed as attractive therapeutic targets in PCa. Ho...

journal_title：Scientific reports

authors： Lafront C,Germain L,Weidmann C,Audet-Walsh É

更新日期：2020-03-04 00:00:00

abstract：:Insulin resistance is common among children with overweight and obesity. However, knowledge about glucose fluctuations in these children is scarce. This study aims to evaluate glycaemic profiles in children with overweight and obesity in free-living conditions, and to examine the association between glycaemic profiles...

journal_title：Scientific reports

authors： Rijks J,Karnebeek K,van Dijk JW,Dorenbos E,Gerver WJ,Stouthart P,Plat J,Vreugdenhil A

更新日期：2016-08-18 00:00:00

abstract：:Herein, we examined the association between cytomegalovirus (CMV) coinfection and the progression of liver fibrosis in hepatitis C virus (HCV) infection, and investigated the effect of CMV coinfection on JAK-STAT pathway. CMV DNAemia was detected by PCR in DNA from controls (n = 120), and HCV patients with early (F0-F...

journal_title：Scientific reports

authors： Ibrahim MK,Khedr A,Bader El Din NG,Khairy A,El Awady MK

更新日期：2017-09-04 00:00:00

abstract：:Detailed structural analyses of the mushroom body which plays critical roles in olfactory learning and memory revealed that it is directly connected with multiple primary sensory centers in Drosophila. Connectivity patterns between the mushroom body and primary sensory centers suggest that each mushroom body lobe proc...

journal_title：Scientific reports

authors： Yagi R,Mabuchi Y,Mizunami M,Tanaka NK

更新日期：2016-07-11 00:00:00

abstract：:The advent of flexible optoelectronic devices has accelerated the development of semiconducting polymeric materials. We seek to replace conventional expensive semiconducting photodetector materials with our cost-effective composite system. We demonstrate in this work the successful fabrication of a photoconductive com...

journal_title：Scientific reports

authors： Tong Y,Zhao X,Tan MC,Zhao R

更新日期：2015-11-16 00:00:00

abstract：:Soils are an important source of nitrogen in many of the world's cropping systems. Especially in low-input production systems, nitrogen release from soil organic matter turn-over is the major part of the crop's nitrogen supply and research suggests that this process is significantly affected by changes in climate. The...

journal_title：Scientific reports

authors： Nendel C,Melzer D,Thorburn PJ

更新日期：2019-04-10 00:00:00

abstract：:Small for gestational age (SGA) newborns are often born from hypertensive pregnancies. This study aimed to compare the systemic metabolism of cortisol (F) in pregnancies with SGA and appropriate for gestational age (AGA) infants, considering both the normotensive (NT) and hypertensive patients. We hypothesized that th...

journal_title：Scientific reports

authors： Siemiątkowska A,Kosicka K,Szpera-Goździewicz A,Krzyścin M,Bręborowicz GH,Główka FK

更新日期：2019-11-29 00:00:00

abstract：:Western wheatgrass (Pascopyrum smithii Rydb.) is an important cool-season forage and turfgrass. However, due to seed dormancy and poor seedling vigor, it is difficult to develop high seed yield production systems, and assessing these components in response to seed yield. Based on multifactor orthogonally designed fiel...

journal_title：Scientific reports

authors： Chen Z,Niu J,Cao X,Jiang W,Cui J,Wang Q,Zhang Q

更新日期：2019-11-29 00:00:00

abstract：:A common philosophy in control theory is the control of disorder by order. Control of decoherence is no exception; strategies aimed at suppressing quantum decoherence adopt this point of view. Here we predict an anomalous phenomenon in open quantum systems-control of disorder by (even more) disorder. It is shown that ...

journal_title：Scientific reports

authors： Jing J,Wu LA

更新日期：2013-09-25 00:00:00

abstract：:Enamel proteins form a scaffold for growing hydroxyapatite crystals during enamel formation. They are then almost completely degraded during enamel maturation, resulting in a protein content of only 1% (w/v) in mature enamel. Nevertheless, this small amount of remaining proteins has important effects on the mechanical...

journal_title：Scientific reports

authors： Baumann T,Carvalho TS,Lussi A

更新日期：2015-10-15 00:00:00

abstract：:Angiosperm mitochondrial genomes (mtDNA) exhibit variable quantities of alien sequences. Many of these sequences are acquired by intracellular gene transfer (IGT) from the plastid. In addition, frequent events of horizontal gene transfer (HGT) between mitochondria of different species also contribute to their expanded...

journal_title：Scientific reports

authors： Gandini CL,Sanchez-Puerta MV

更新日期：2017-03-06 00:00:00

abstract：:Gastric cancer is one of the most aggressive cancers and is the second leading cause of cancer death worldwide. Approximately 40% of global gastric cancer cases occur in China, with peritoneal metastasis being the prevalent form of recurrence and metastasis in advanced disease. Currently, there are limited clinical ap...

journal_title：Scientific reports

authors： Zhang J,Huang JY,Chen YN,Yuan F,Zhang H,Yan FH,Wang MJ,Wang G,Su M,Lu G,Huang Y,Dai H,Ji J,Zhang J,Zhang JN,Jiang YN,Chen SJ,Zhu ZG,Yu YY

更新日期：2015-09-02 00:00:00

abstract：:Intelligent development is an inevitable choice for the green development of manufacturing enterprises, environmental regulations and green innovation play an important role in the intelligent development of manufacturing enterprises. By analyzing the interrelationships between environmental regulations, green innovat...

journal_title：Scientific reports

authors： Meng F,Xu Y,Zhao G

更新日期：2020-09-02 00:00:00

abstract：:Plate subduction continuously transports crustal materials with high-δ(18)O values down to the mantle wedge, where mantle peridotites are expected to achieve the high-δ(18)O features. Elevated δ(18)O values relative to the upper mantle value have been reported for magmas from some subduction zones. However, peridotite...

journal_title：Scientific reports

authors： Liu CZ,Wu FY,Chung SL,Li QL,Sun WD,Ji WQ

更新日期：2014-02-28 00:00:00

abstract：:The ammonia removal as well as the current efficiency during electrolysis was investigated by using a vermiculite-packed electrochemical reactor under continuous mode. Experimental results showed that adsorption of ammonia by vermiculite and electrolytic desorption of ammonia simultaneously existed in the reactor, lea...

journal_title：Scientific reports

authors： Li L,Yao J,Fang X,Huang Y,Mu Y

更新日期：2017-01-19 00:00:00

abstract：:Magma transport through the Earth's crust occurs dominantly via sheet intrusions, such as dykes and cone-sheets, and is fundamental to crustal evolution, volcanic eruptions and geochemical element cycling. However, reliable methods to reconstruct flow direction in solidified sheet intrusions have proved elusive. Aniso...

journal_title：Scientific reports

authors： Andersson M,Almqvist BS,Burchardt S,Troll VR,Malehmir A,Snowball I,Kübler L

更新日期：2016-06-10 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Sheu JR,Chen ZC,Jayakumar T,Chou DS,Yen TL,Lee HN,Pan SH,Hsia CH,Yang CH,Hsieh CY

更新日期：2020-04-06 00:00:00

abstract：:Whether an infectious disease threat to wildlife arises from pathogen introduction or the increased incidence of an already-present agent informs mitigation policy and actions. The prior absence of a pathogen can be difficult to establish, particularly in free-living wildlife. Subsequent to the epidemic emergence of t...

journal_title：Scientific reports

authors： Cunningham AA,Smith F,McKinley TJ,Perkins MW,Fitzpatrick LD,Wright ON,Lawson B

更新日期：2019-03-12 00:00:00

abstract：:In the current study, the thermodynamics of the slag-metal equilibrium reaction between Inconel 718 Ni-based alloy and CaF2-CaO-Al2O3-MgO-TiO2 electroslag remelting (ESR)-type slags were systematically investigated in the temperature range from 1773 to 1973 K (1500 to 1700 °C). The equilibrium Al content increased wit...

journal_title：Scientific reports

authors： Duan S,Shi X,Mao M,Yang W,Han S,Guo H,Guo J

更新日期：2018-03-27 00:00:00

abstract：:Surface colonization by microorganisms leads to the formation of biofilms, i.e. aggregates of bacteria embedded within a matrix of extracellular polymeric substance. This promotes adhesion to the surface and protects bacterial community, providing an antimicrobial-resistant environment. The inhibition of biofilm growt...

journal_title：Scientific reports

authors： Sportelli MC,Tütüncü E,Picca RA,Valentini M,Valentini A,Kranz C,Mizaikoff B,Barth H,Cioffi N

更新日期：2017-09-19 00:00:00

abstract：:We report a recent experimental simulation of a controlled-NOT gate operation based on polarization correlation measurements of thermal fields in photon-number fluctuations. The interference between pairs of correlated paths at the very heart of these experiments has the potential for the simulation of correlations be...

journal_title：Scientific reports

authors： Peng T,Tamma V,Shih Y

更新日期：2016-07-21 00:00:00

abstract：:Musical performance requires extremely fast and dexterous limb movements. The underlying biological mechanisms have been an object of interest among scientists and non-scientists for centuries. Numerous studies of musicians and non-musicians have demonstrated that neuroplastic adaptations through early and deliberate ...

journal_title：Scientific reports

authors： Furuya S,Oku T,Miyazaki F,Kinoshita H

更新日期：2015-10-27 00:00:00

abstract：:Mesoporous silica nanoscale microsphere (MSNM), with a special morphology, high porosity, large pore volume and specific surface area, was successfully prepared and used as the matrix material of lauric acid (LA) to prepare a favorable shape-stabilized phase change material (LA/MSNM). The porous network structure of M...

journal_title：Scientific reports

authors： Zhang Z,Wang J,Tang X,Liu Y,Han Z,Chen Y

更新日期：2019-11-05 00:00:00

abstract：:The critical importance of human milk to infants and even human civilization has been well established. Yet our understanding of the milk microbiome has been limited to cataloguing OTUs and computation of community diversity. To the best of our knowledge, there has been no report on the bacterial interactions within t...

journal_title：Scientific reports

authors： Sam Ma Z,Guan Q,Ye C,Zhang C,Foster JA,Forney LJ

更新日期：2015-02-05 00:00:00

abstract：:Targeted antineoplastic agents show great promise in the treatment of cancer, having the ability to impart cytotoxicity only to specific tumor types. However, these therapies do not experience uniform uptake throughout tumors, leading to sub-lethal cell killing that can impart treatment resistance, and cause problemat...

journal_title：Scientific reports

authors： Klein OJ,Yuan H,Nowell NH,Kaittanis C,Josephson L,Evans CL

更新日期：2017-10-17 00:00:00

abstract：:Neuropsychological assessment of human visual processing capabilities strongly depends on visual testing conditions including room lighting, stimuli, and viewing-distance. This limits standardization, threatens reliability, and prevents the assessment of core visual functions such as visual processing speed. Increasin...

journal_title：Scientific reports

authors： Foerster RM,Poth CH,Behler C,Botsch M,Schneider WX

更新日期：2016-11-21 00:00:00

abstract：:Guanine-rich quadruplex (G-QD) are formed by conversion of nucleotides with specific sequences by stabilization of positively charged K+ or Na+. These G-QD structures differentially absorb two-directional (right- and left-handed) circularly polarized light, which can discriminate the parallel or anti-parallel structur...

journal_title：Scientific reports

authors： Kim R,Youn YS,Kang M,Kim E

更新日期：2020-11-24 00:00:00

abstract：:Mammalian spermatogenesis is a classic adult stems cell-dependent process, supported by the self-renewal and differentiation of spermatogonial stem cells (SSCs). However, the identification of SSCs and elucidation of their behaviors in undisturbed testis has long been a big challenge. Here, we generated a knock-in mou...

journal_title：Scientific reports

authors： Sun F,Xu Q,Zhao D,Degui Chen C

更新日期：2015-12-01 00:00:00

abstract：:Tuberculosis treatment includes broad-spectrum antibiotics such as rifampicin, streptomycin and fluoroquinolones, which are also used against other pathogenic bacteria. We developed Drug Resistance Associated Genes database (DRAGdb), a manually curated repository of mutational data of drug resistance associated genes ...

journal_title：Scientific reports

authors： Ghosh A,N S,Saha S

更新日期：2020-06-02 00:00:00