Survey of drug resistance associated gene mutations in Mycobacterium tuberculosis, ESKAPE and other bacterial species.

abstract：:The balance between ovarian folliculogenesis and follicular atresia is critical for female fertility and is strictly regulated by a complex network of neuroendocrine and intra-ovarian signals. Despite the numerous functions executed by granulosa cells (GCs) in ovarian physiology, the role of multifunctional proteins a...

journal_title：Scientific reports

authors： Arcos A,de Paola M,Gianetti D,Acuña D,Velásquez ZD,Miró MP,Toro G,Hinrichsen B,Muñoz RI,Lin Y,Mardones GA,Ehrenfeld P,Rivera FJ,Michaut MA,Batiz LF

更新日期：2017-09-18 00:00:00

abstract：:Cortical neural activities lead to changes in the cerebral blood flow (CBF), which involves astrocytic control of cerebrovascular tone. However, the manner in which astrocytic activity specifically leads to vasodilation or vasoconstriction is difficult to determine. Here, cortical astrocytes genetically expressing a l...

journal_title：Scientific reports

authors： Masamoto K,Unekawa M,Watanabe T,Toriumi H,Takuwa H,Kawaguchi H,Kanno I,Matsui K,Tanaka KF,Tomita Y,Suzuki N

更新日期：2015-06-16 00:00:00

abstract：:A neurogenic pathway, involving airway TRPV-1, has been implicated in acute cardiovascular events occurring after peaks of air pollution. We tested whether inhaled prostaglandin-E2 (PGE2) and bradykinin (BK) regulate TRPV-1 activity in vivo by changing cough response to capsaicin (CPS) and affecting heart rate variabi...

journal_title：Scientific reports

authors： Liviero F,Scarpa MC,De Stefani D,Folino F,Campisi M,Mason P,Iliceto S,Pavanello S,Maestrelli P

更新日期：2020-09-16 00:00:00

abstract：:The negatively-charged nitrogen vacancy (NV(-)) center in diamond is of great interest for quantum information processing and quantum key distribution applications due to its highly desirable long coherence times at room temperature. One of the challenges for their use in these applications involves the requirement to...

journal_title：Scientific reports

authors： Khalid A,Chung K,Rajasekharan R,Lau DW,Karle TJ,Gibson BC,Tomljenovic-Hanic S

更新日期：2015-06-25 00:00:00

abstract：:Psoriatic arthritis (PsA) patients have increased risk of both atherosclerosis and osteoporosis. Previous studies revealed that IL-33/ST2 axis may be related to both conditions; however, these associations were never evaluated in a single patients' group. Here we explored the association among plasma levels of IL-33 a...

journal_title：Scientific reports

authors： Shen J,Shang Q,Wong CK,Li EK,Kun EW,Cheng IT,Li M,Li TK,Zhu TY,Yu CM,Qin L,Tam LS

更新日期：2016-08-24 00:00:00

abstract：:Although biophysical yield responses to local warming have been studied, we know little about how crop yield growth-a function of climate and technology-responds to global temperature and socioeconomic changes. Here, we present the yield growth of major crops under warming conditions from preindustrial levels as simul...

journal_title：Scientific reports

authors： Iizumi T,Furuya J,Shen Z,Kim W,Okada M,Fujimori S,Hasegawa T,Nishimori M

更新日期：2017-08-10 00:00:00

abstract：:In this study, dye-sensitized solar cells (DSSCs) has been assembled with poly(1-vinylpyrrolidone-co-vinyl acetate) (P(VP-co-VAc)) gel polymer electrolytes (GPEs) which have been incorporated with binary salt and an ionic liquid. The potential of this combination was studied and reported. The binary salt system GPEs w...

journal_title：Scientific reports

authors： Ming NH,Ramesh S,Ramesh K

更新日期：2016-06-08 00:00:00

abstract：:Transposable elements are emerging as an important source of cis-acting regulatory sequences and epigenetic marks that could influence gene expression. However, few studies have dissected the role of specific transposable element insertions on epigenetic gene regulation. Bari-Jheh is a natural transposon that mediates...

journal_title：Scientific reports

authors： Guio L,Vieira C,González J

更新日期：2018-08-15 00:00:00

abstract：:Cold agglutinin disease (CAD) is a rare form of autoimmune haemolytic anaemia, and because of its rareness, there is no standard treatment for CAD patients. We retrospectively analysed the response to rituximab-containing therapy in CAD patients at our hospital. All patients received rituximab-containing therapy for a...

journal_title：Scientific reports

authors： Jia MN,Qiu Y,Wu YY,Cai H,Zhou DB,Cao XX,Li J

更新日期：2020-07-29 00:00:00

abstract：:Despite recent advances, the myocardial microstructure remains imperfectly understood. In particular, bundles of cardiomyocytes have been observed but their three-dimensional organisation remains debated and the associated mechanical consequences unknown. One of the major challenges remains to perform multiscale obser...

journal_title：Scientific reports

authors： Tueni N,Vizet J,Genet M,Pierangelo A,Allain JM

更新日期：2020-11-25 00:00:00

abstract：:The prevalence of a macrophage phenotype in atherosclerotic plaque may drive its progression and/or instability. Macrophages from coronary plaques are not available, and monocyte-derived macrophages (MDMs) are usually considered as a surrogate. We compared the MDM profile obtained from coronary artery disease (CAD) pa...

journal_title：Scientific reports

authors： Eligini S,Cosentino N,Fiorelli S,Fabbiocchi F,Niccoli G,Refaat H,Camera M,Calligaris G,De Martini S,Bonomi A,Veglia F,Fracassi F,Crea F,Marenzi G,Tremoli E

更新日期：2019-06-18 00:00:00

abstract：:Micropyles in insects are small openings that allow sperm entry into, and the number was usually decreased on unfertilized and (or) undeveloped eggs. However, reports showed that Harmonia axyridis, a reproductive success model, deposited similar number of micropyles on undeveloped and developing eggs. Thus, it was con...

journal_title：Scientific reports

authors： Sun YX,Hao YN,Liu CZ,Wang SS

更新日期：2019-09-04 00:00:00

abstract：:The molecular bases of the Frank-Starling law of the heart and of its cellular counterpart, the length dependent activation (LDA), are largely unknown. However, the recent discovery of the thick filament activation, a second pathway beside the well-known calcium mediated thin filament activation, is promising for eluc...

journal_title：Scientific reports

authors： Marcucci L,Washio T,Yanagida T

更新日期：2019-02-04 00:00:00

abstract：:Artificial interface anisotropy is demonstrated in alternating Co/Pt and Co/Pd stripe patterns, providing a means of forming magnetic anisotropy using lithography. In-plane hysteresis loops measured along two principal directions are explained in depth by two competing shape and interface anisotropies, thus confirming...

journal_title：Scientific reports

authors： Kim SN,Nam YJ,Kim YD,Choi JW,Lee H,Lim SH

更新日期：2016-05-24 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Delplancke TDJ,de Seymour JV,Tong C,Sulek K,Xia Y,Zhang H,Han TL,Baker PN

更新日期：2020-02-21 00:00:00

abstract：:This study aimed to define the width and length of the dental arch in 12-year-old Vietnamese children, and to elucidate differences between genders and among ethnic groups. A cross-sectional study was conducted in 4565 12 years-old children from the 4 major ethnic groups in Vietnam (Kinh, Muong, Thai, and Tay), with a...

journal_title：Scientific reports

authors： Dung TM,Ngoc VTN,Hiep NH,Khoi TD,Xiem VV,Chu-Dinh T,Cieslar-Pobuda A,Stoufi E,Show PL,Tao Y,Bac ND,Van Ba N,Le QA,Pham VH,Chu DT

更新日期：2019-02-28 00:00:00

abstract：:The synthesis and subsequent genomic integration of DNA that is complementary to the genomes of non-retroviral RNA viruses are rarely observed. However, upon infection of various human cell lines and primary fibroblasts with the vesicular stomatitis virus (VSV), we detected DNA complementary to the VSV RNA. The VSV DN...

journal_title：Scientific reports

authors： Shimizu A,Nakatani Y,Nakamura T,Jinno-Oue A,Ishikawa O,Boeke JD,Takeuchi Y,Hoshino H

更新日期：2014-05-30 00:00:00

abstract：:Our understanding of innate immune responses in human rectal mucosal tissues (RM) and their contributions to promoting or restricting HIV transmission is limited. We defined the RM composition of innate and innate-like cell subsets, including plasmacytoid dendritic cells; CD1c + myeloid DCs; neutrophils; macrophages; ...

journal_title：Scientific reports

authors： Smith SA,Murray PM,Amancha PK,Ackerley CG,Hu YJ,Amara RR,Kelley CF

更新日期：2020-11-19 00:00:00

abstract：:To effectively manage a watershed and successfully restore a river system, it is very important to assess the toxicity of sediments and identify the substances causing the toxicity. Seventy-six sediments collected in the Haihe River Basin (HRB) in China were screened for acute toxicity using Chironomus dilutus. We fou...

journal_title：Scientific reports

authors： Zhu X,Shan B,Tang W,Zhang C

更新日期：2017-05-03 00:00:00

abstract：:Metabotropic glutamate receptor subtype 1 (mGluR1) is a crucial pharmacological target for several central nervous system disorders. In this study, we aimed to monitor in vivo regional changes of mGluR1 related to neuroinflammation in the brains of rats after pilocarpine-induced status epilepticus (PISE) using longitu...

journal_title：Scientific reports

authors： Yamasaki T,Fujinaga M,Mori W,Zhang Y,Wakizaka H,Nengaki N,Xie L,Hatori A,Zhang MR

更新日期：2017-11-02 00:00:00

abstract：:Obesity is a progressive, chronic disease, which can be caused by long-term miscommunication between organs. It remains challenging to understand how chronic dysfunction in a particular tissue remotely impairs other organs to eventually imbalance organismal energy homeostasis. Here we introduce RNAi Pulse Induction (R...

journal_title：Scientific reports

authors： Xu Y,Borcherding AF,Heier C,Tian G,Roeder T,Kühnlein RP

更新日期：2019-05-06 00:00:00

abstract：:Bacterial infection and sepsis are common complications of chronic kidney disease (CKD). A vicious cycle of increased gut permeability, endotoxemia, inadequate activation of the innate immune system and resulting innate immune dysfunction is hypothesized. We assessed endotoxemia, neutrophil function and its relation t...

journal_title：Scientific reports

authors： Lemesch S,Ribitsch W,Schilcher G,Spindelböck W,Hafner-Gießauf H,Marsche G,Pasterk L,Payerl D,Schmerböck B,Tawdrous M,Rosenkranz AR,Stiegler P,Kager G,Hallström S,Oettl K,Eberhard K,Horvath A,Leber B,Stadlbauer V

更新日期：2016-10-04 00:00:00

abstract：:Epidemiological studies using saliva have revealed relationships between the oral microbiome and many oral and systemic diseases. However, when collecting from a large number of participants such as a large-scale cohort study, the time it takes to collect saliva can be a problem. Mouth-rinsed water, which is water tha...

journal_title：Scientific reports

authors： Jo R,Nishimoto Y,Umezawa K,Yama K,Aita Y,Ichiba Y,Murakami S,Kakizawa Y,Kumagai T,Yamada T,Fukuda S

更新日期：2019-11-06 00:00:00

abstract：:The live attenuated yellow fever (YF) vaccine is a highly effective human vaccine and induces long-term protective neutralizing antibodies directed against the viral envelope protein E. The generation of such antibodies requires the help of CD4 T cells which recognize peptides derived from proteins in virus particles ...

journal_title：Scientific reports

authors： Koblischke M,Mackroth MS,Schwaiger J,Fae I,Fischer G,Stiasny K,Heinz FX,Aberle JH

更新日期：2017-08-21 00:00:00

abstract：:Mass spectrometry (MS) for the detection of proteins is an indispensable tool for evaluating the biological processes of the proteome. Proteomics frequently requires proteolysis of proteins into peptide fragments. Proteins can be refractory to ideal proteolysis at the sequence level rendering them difficult to analyze...

journal_title：Scientific reports

authors： Reyna C,Mba Medie F,Champion MM,Champion PA

更新日期：2016-09-14 00:00:00

abstract：:Because of the critical role of transportation in modern times, one of the most successful application areas of statistical physics of complex networks is the study of traffic dynamics. However, the vast majority of works treat transportation networks as an isolated system, which is inconsistent with the fact that man...

journal_title：Scientific reports

authors： Du WB,Zhou XL,Jusup M,Wang Z

更新日期：2016-01-21 00:00:00

abstract：:We report the fabrication of flower-like CuO nanostructured surfaces via submerged photo-synthesis of crystallites (SPSC), which requires only UV illumination in neutral water. In this paper, we discuss the reaction mechanism of the photochemical formation of the SPSC-fabricated CuO nanostructures in detail based on s...

journal_title：Scientific reports

authors： Nishino F,Jeem M,Zhang L,Okamoto K,Okabe S,Watanabe S

更新日期：2017-04-21 00:00:00

abstract：:Huntington's disease (HD) is a monogenetic neurodegenerative disorder that is caused by the expansion of a polyglutamine region within the huntingtin (HTT) protein, but there is still an incomplete understanding of the molecular mechanisms that drive pathology. Expression of the mutant form of HTT is a key aspect of d...

journal_title：Scientific reports

authors： Fodale V,Pintauro R,Daldin M,Altobelli R,Spiezia MC,Bisbocci M,Macdonald D,Bresciani A

更新日期：2020-12-17 00:00:00

abstract：:Recent studies have discovered an intriguing nonstationary relationship between El Ninõ-Southern Oscillation (ENSO) and the Western Pacific (WP) teleconnection pattern, one of the most prominent winter atmospheric circulation patterns in the North Pacific, with a regime-dependent interdecadal modulation of significant...

journal_title：Scientific reports

authors： Park YH,Kim BM,Pak G,Yamamoto M,Vivier F,Durand I

更新日期：2018-06-22 00:00:00

abstract：:This corrects the article DOI: 10.1038/srep44499. ...

journal_title：Scientific reports

authors： Korkali M,Veneman JG,Tivnan BF,Bagrow JP,Hines PDH

更新日期：2018-03-19 00:00:00