Abstract:
:This corrects the article DOI: 10.1038/srep44499.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Korkali M,Veneman JG,Tivnan BF,Bagrow JP,Hines PDHdoi
10.1038/srep46959subject
Has Abstractpub_date
2018-03-19 00:00:00pages
46959issn
2045-2322pii
srep46959journal_volume
8pub_type
已发布勘误abstract::A polarized macrophage response into inflammatory (M1) or regenerative/anti-inflammatory (M2) phenotypes is critical in host response to multiple intracellular bacterial infections. Ehrlichia is an obligate Gram-negative intracellular bacterium that causes human monocytic ehrlichiosis (HME): a febrile illness that may...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-50320-y
更新日期:2019-10-01 00:00:00
abstract::We provide a proof for the necessity of quantizing fundamental interactions demonstrating that a quantum version is needed for any non trivial conservative interaction whose strength depends on the relative distance between two objects. Our proof is based on a consistency argument that in the presence of a classical f...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-47844-8
更新日期:2019-08-06 00:00:00
abstract::Glial fibrillary acidic protein expressing (GFAP+) glia modulate nociceptive neuronal activity in both the peripheral nervous system (PNS) and the central nervous system (CNS). Resident GFAP+ glia in dorsal root ganglia (DRG) known as satellite glial cells (SGCs) potentiate neuronal activity by releasing pro-inflammat...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-71073-z
更新日期:2020-08-25 00:00:00
abstract::A two-dimensional (2D) material placed on an atomically flat substrate can lead to the formation of surface nanobubbles trapping different types of substances. In this paper graphene nanobubbles of the radius of 7-34 nm with argon atoms inside are studied using molecular dynamics (MD). All modeled graphene nanobubbles...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-18226-9
更新日期:2017-12-20 00:00:00
abstract::Circular RNAs (circRNAs) are covalently closed circular non-coding RNAs. Due to their structure, circRNAs are more stable and have longer half-lives than linear RNAs making them good candidates for disease biomarkers. Despite the scientific relevance of these molecules, the study of circRNAs in non-model organisms is ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79781-2
更新日期:2021-01-11 00:00:00
abstract::Understanding mechanisms mediating tumor metastasis is crucial for diagnostic and therapeutic targeting. Here, we take advantage of a transparent embryonic zebrafish xenograft model (eZXM) to visualize and track metastatic cells in real time using selective plane illumination microscopy (SPIM) for up to 30 h. Injected...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-69956-2
更新日期:2020-08-06 00:00:00
abstract::In community ecology, it is important to understand the distribution of communities along environmental and spatial gradients. However, it is common for the residuals of models investigating those relationships to be very high (> 50%). It is believed that species' intrinsic characteristics such as rarity can contribut...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-76833-5
更新日期:2020-11-13 00:00:00
abstract::Controlling the angular momentum of spins with very short external perturbations is a key issue in modern magnetism. For example it allows manipulating the magnetization for recording purposes or for inducing high frequency spin torque oscillations. Towards that purpose it is essential to modify and control the angula...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep08511
更新日期:2015-02-17 00:00:00
abstract::Rheumatoid arthritis (RA) patients have been observed to be at a lower risk of developing Alzheimer's Disease (AD). Clinical trials have showed no relationship between nonsteroidal anti-inflammatory drug (NSAID) use and AD. The aim of this study was to establish if there is a causal link between RA and AD. A systemati...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/s41598-017-13168-8
更新日期:2017-10-09 00:00:00
abstract::We evaluated the performance of CSF biomarkers for predicting risk of clinical decline and conversion to dementia in non-demented patients with cognitive symptoms. CSF samples from patients in two multicentre longitudinal studies (ADNI, n = 619; BioFINDER, n = 431) were analysed. Aβ(1-42), tTau and pTau CSF concentrat...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-54204-z
更新日期:2019-12-13 00:00:00
abstract::Foaming negatively affects anaerobic digestion of food waste (FW). To identify the causes of foaming, reactor performance and microbial community dynamics were investigated in three mesophilic digesters treating FW. The digesters were operated under different modes, and foaming was induced with several methods. Prolif...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-14258-3
更新日期:2017-10-20 00:00:00
abstract::Previous studies have suggested that microRNA-107 (miR-107) regulates cell migration in tumor and promotes Hypoxia Inducible Factor 1α (HIF1α) regulated angiogenesis under hypoxia. We found that miR-107 was strongly expressed in ischemic boundary zone (IBZ) after permanent middle cerebral artery occlusion (pMCAO) in r...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13316
更新日期:2015-08-21 00:00:00
abstract::Transmembrane receptor clustering is a ubiquitous phenomenon in pro- and eukaryotic cells to physically sense receptor/ligand interactions and subsequently translate an exogenous signal into a cellular response. Despite that receptor cluster formation has been described for a wide variety of receptors, ranging from ch...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep28940
更新日期:2016-06-29 00:00:00
abstract::Antimicrobial peptides, produced by innate immune system of hosts in response to invading pathogens, are capable of fighting against a spectrum of bacteria, viruses, fungi, parasites and cancer cells. Here, a recombinant silkworm AMP Bmattacin2 from heterologous expression is studied, indicating a broad spectrum of an...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31149
更新日期:2016-08-09 00:00:00
abstract::In this work, we present a novel ascorbic acid (AA) sensor applied to the detection of AA in human sera and pharmaceuticals. A series of Au nanoparticles (NPs) and graphene oxide sheets (Au NP/GO) composites were successfully synthesized by reduction of gold (III) using sodium citrate. Then the Au NP/GO composites wer...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep07515
更新日期:2014-12-17 00:00:00
abstract::Obesity, often represented by higher body mass index (BMI), is not yet fully understood as a potential risk factor for poor clinical outcomes of prostate cancer (PCa) after radical prostatectomy (RP). This study aimed to evaluate the relationship between BMI and biochemical recurrence (BCR)-free survival in RP patient...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-30473-y
更新日期:2018-08-10 00:00:00
abstract::An increasing number of industrial applications need superstrength steels. It is known that refined grains and nanoscale precipitates can increase strength. The hardest martensitic steel reported to date is C0.8 steel, whose nanohardness can reach 11.9 GPa through incremental interstitial solid solution strengthening....
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep36810
更新日期:2016-11-28 00:00:00
abstract::The Japanese macaque (Macaca fuscata) exhibits a species-specific communication sound called the "coo call" to locate group members and maintain within-group contact. Monkeys have been demonstrated to be capable of discriminating between individuals based only on their voices, but there is still debate regarding how t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep32042
更新日期:2016-08-23 00:00:00
abstract::The stratum corneum plays a crucial role in epidermal barrier function. Various changes occur in granular cells at the uppermost stratum granulosum during cornification. To understand the temporal details of this process, we visualized the cell shape and organelles of cornifying keratinocytes in a living human epiderm...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-62240-3
更新日期:2020-03-26 00:00:00
abstract::We compared the effects of 12-week programs of resistance training (RT), high-intensity interval aerobic training (HIAT), and moderate-intensity continuous aerobic training (MICT). The primary goal was to evaluate the therapeutic effects of the exercise modalities for the management of nonalcoholic fatty liver disease...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43029
更新日期:2017-02-22 00:00:00
abstract::Recent studies suggest a functional involvement of Epithelial-Mesenchymal Transition (EMT) in tumor chemoresistance. Specifically, EMT is associated with chemoresistance and poor prognosis in triple-negative breast cancer. However, no effective therapy targeting EMT has been developed. Here, we report that periostin, ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-22340-7
更新日期:2018-03-05 00:00:00
abstract::Starting from the dataset of the publication corpus of the APS during the period 1955-2009, we reconstruct the individual researchers trajectories, namely the list of the consecutive affiliations for each scholar. Crossing this information with different geographic datasets we embed these trajectories in a spatial fra...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep04860
更新日期:2014-05-07 00:00:00
abstract::Geriatric trauma is a major socio-economic problem, especially among the aging Japanese society. Geriatric people are more vulnerable to trauma than younger people; thus, their outcomes are often severe. This study evaluates the characteristics of geriatric trauma divided by age in the Japanese population. We evaluate...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-76149-4
更新日期:2020-11-05 00:00:00
abstract::The efficacy of different modalities of treating breast cancer is inhibited by several limitations such as off-targeted drug distribution, rapid drug clearance, and drug resistance. To overcome these limitations, we developed Lf-Doxo-PMNSs for combined chemo-MF-PTT. The PMNSs were synthesized by hydrothermal method an...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-62429-6
更新日期:2020-04-03 00:00:00
abstract::Impurities in superconductors and their induced bound states are important both for engineering novel states such as Majorana zero-energy modes and for probing bulk properties of the superconducting state. The high-temperature cuprates offer a clear advantage in a much larger superconducting order parameter, but the n...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep44107
更新日期:2017-03-10 00:00:00
abstract::Truffles (Tuber spp.) are the fruiting bodies of symbiotic fungi, which are prized food delicacies. The marked aroma variability observed among truffles of the same species has been attributed to a series of factors that are still debated. This is because factors (i.e. genetics, maturation, geographical location and t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-27620-w
更新日期:2018-06-18 00:00:00
abstract::The functions of purinergic P2 receptors (P2Rs) for extracellular adenosine triphosphate (ATP) are poorly understood. Here, for the first time, we show that activation of P2Rs in an important arousal region, the basal forebrain (BF), promotes wakefulness, whereas inhibition of P2Rs promotes sleep. Infusion of a non-hy...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-29103-4
更新日期:2018-07-16 00:00:00
abstract::Circulating tumor cells (CTCs) are important clinical indicators for prognosis and treatment efficacy. However, CTC investigation is hampered by their low number, making the establishment of permanent CTC lines very challenging. We derived and characterized nine CTC lines using blood samples from a patient with metast...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-34365-z
更新日期:2018-10-29 00:00:00
abstract::Bioluminescence resonance energy transfer (BRET) has been a vital tool for understanding G protein-coupled receptor (GPCR) function. It has been used to investigate GPCR-protein and/or -ligand interactions as well as GPCR oligomerisation. However the utility of BRET is limited by the requirement that the fusion protei...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-03486-2
更新日期:2017-06-09 00:00:00
abstract::Astaxanthin is a ketocarotenoid produced by photosynthetic microalgae. It is a pigment of high industrial interest in acquaculture, cosmetics, and nutraceutics due to its strong antioxidant power. Haematococcus pluvialis, a fresh-water microalga, accumulates high levels of astaxanthin upon oxidative stress, reaching v...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-16641-6
更新日期:2017-11-24 00:00:00