MicroRNA-107 contributes to post-stroke angiogenesis by targeting Dicer-1.

abstract：:For a high-performance cocatalyst-modified photocatalyst, an effective interfacial separation of photogenerated electron from its corresponding holes and its following reduction reaction at the active sites are highly required. However, it is difficult for a single-component cocatalyst to simultaneously realize the cr...

journal_title：Scientific reports

authors： Yu H,Tian J,Chen F,Wang P,Wang X

更新日期：2015-08-14 00:00:00

abstract：:Detection of subclinical mastitis (SCM) in its initial stage can save great economic losses, improve milk quality and animal welfare. We have developed a semiquantitative lateral flow assay for the detection of SCM in dairy cows targeting myeloperoxidase (MPO) enzyme of milk neutrophils. A competitive immunoassay form...

journal_title：Scientific reports

authors： Alhussien MN,Dang AK

更新日期：2020-07-07 00:00:00

abstract：:In this study, we evaluated the consequences of reducing Galectin-1 (Gal-1) in the tumor micro-environment (TME) of glioblastoma multiforme (GBM), via nose-to-brain transport. Gal-1 is overexpressed in GBM and drives chemo- and immunotherapy resistance. To promote nose-to-brain transport, we designed siRNA targeting G...

journal_title：Scientific reports

authors： Van Woensel M,Mathivet T,Wauthoz N,Rosière R,Garg AD,Agostinis P,Mathieu V,Kiss R,Lefranc F,Boon L,Belmans J,Van Gool SW,Gerhardt H,Amighi K,De Vleeschouwer S

更新日期：2017-04-27 00:00:00

abstract：:Bioerosion is a process with a high socio-economic impact that contributes to coastal retreat, and likely to increase with climate change. Whereas limestone bioerosion is well explained by a combination of mechanical and chemical pathways, the bioerosion mechanisms of silicates, which are harder and chemically more re...

journal_title：Scientific reports

authors： Daval D,Guyot F,Bolotov IN,Vikhrev IV,Kondakov AV,Lyubas AA,Bychkov AY,Yapaskurt VO,Cabié M,Pokrovsky OS

更新日期：2020-08-07 00:00:00

abstract：:Efficient interventions to reduce blood triglycerides are few; newer and more tolerable intervention targets are needed. Understanding the molecular mechanisms underlying blood triglyceride levels variation is key to identifying new therapies. To explore the role of epigenetic mechanisms on triglyceride levels, a bloo...

journal_title：Scientific reports

authors： Truong V,Huang S,Dennis J,Lemire M,Zwingerman N,Aïssi D,Kassam I,Perret C,Wells P,Morange PE,Wilson M,Trégouët DA,Gagnon F

更新日期：2017-09-11 00:00:00

abstract：:Fatal Familial Insomnia (FFI) is a genetic prion disease caused by a point mutation in the prion protein gene (PRNP) characterized by prominent thalamic atrophy, diffuse astrogliosis and moderate deposition of PrPSc in the brain. Here, for the first time, we demonstrate that the olfactory mucosa (OM) of patients with ...

journal_title：Scientific reports

authors： Redaelli V,Bistaffa E,Zanusso G,Salzano G,Sacchetto L,Rossi M,De Luca CM,Di Bari M,Portaleone SM,Agrimi U,Legname G,Roiter I,Forloni G,Tagliavini F,Moda F

更新日期：2017-04-07 00:00:00

abstract：:Thaumarchaeota and the gene encoding for a subunit of ammonia monooxygenase (amoA) are ubiquitous in Polar Seas, and some Thaumarchaeota also have a gene coding for ureC, diagnostic for urease. Using quantitative PCR we investigated the occurrence of genes and transcripts of ureC and amoA in Arctic samples from winter...

journal_title：Scientific reports

authors： Pedneault E,Galand PE,Potvin M,Tremblay JÉ,Lovejoy C

更新日期：2014-04-11 00:00:00

abstract：:Cartilage loss is a leading cause of disability among adults and effective therapy remains elusive. Neonatal chondrocytes (NChons) are an attractive allogeneic cell source for cartilage repair, but their clinical translation has been hindered by scarce donor availability. Here we examine the potential for catalyzing c...

journal_title：Scientific reports

authors： Lai JH,Kajiyama G,Smith RL,Maloney W,Yang F

更新日期：2013-12-19 00:00:00

abstract：:Neural networks can efficiently encode the probability distribution of errors in an error correcting code. Moreover, these distributions can be conditioned on the syndromes of the corresponding errors. This paves a path forward for a decoder that employs a neural network to calculate the conditional distribution, then...

journal_title：Scientific reports

authors： Krastanov S,Jiang L

更新日期：2017-09-08 00:00:00

abstract：:Chondrichthyes - sharks, rays, skates, and chimeras, are among the most threatened and data deficient vertebrate species. Global demand for shark and ray derived products, drives unregulated and exploitative fishing practices, which are in turn facilitated by the lack of ecological data required for effective conserva...

journal_title：Scientific reports

authors： Johri S,Solanki J,Cantu VA,Fellows SR,Edwards RA,Moreno I,Vyas A,Dinsdale EA

更新日期：2019-03-14 00:00:00

abstract：:Embryonic cryopreservation has a relatively low survival rate because of cytoskeletal damage. However, molecular anti-freezing mechanisms have been largely unexplored. This study investigated the significance of RhoA, involved in embryonic development, and the Rho/RhoA-associated kinase (ROCK) signalling pathway in cr...

journal_title：Scientific reports

authors： Gu M,Ni H,Sheng X,Pauciullo A,Liu Y,Guo Y

更新日期：2017-07-27 00:00:00

abstract：:Subsea hypersaline anoxic brine pools are among the most extreme habitable environments on Earth that offer clues to life on other planets. Brine is toxic to macrofauna as remotely operated vehicles commonly observe dead and preserved remains in brine pools. While brine pools are often assumed to be stable stratified ...

journal_title：Scientific reports

authors： Sawyer DE,Mason RA,Cook AE,Portnov A

更新日期：2019-01-15 00:00:00

abstract：:Biofilms are complex microbial communities that present serious contamination risks to our environment and health. In this study, atmospheric air plasma and airborne acoustic ultrasound technology were applied to inactivate Escherichia coli and Listeria innocua biofilms. Both technologies were efficient in controlling...

journal_title：Scientific reports

authors： Patange AD,Simpson JC,Curtin JF,Burgess CM,Cullen PJ,Tiwari BK

更新日期：2021-01-27 00:00:00

abstract：:Diets high in advanced glycation end products (AGEs) are thought to be detrimental to cardiovascular health. However, there remains uncertainty about the beneficial effect of a low AGE diet on cardiovascular risk factors and inflammatory markers in overweight individuals. We thus performed a randomised, double blind, ...

journal_title：Scientific reports

authors： Baye E,de Courten MP,Walker K,Ranasinha S,Earnest A,Forbes JM,de Courten B

更新日期：2017-06-23 00:00:00

abstract：:We present a table-top beamline providing a soft X-ray supercontinuum extending up to 370 eV from high-order harmonic generation with sub-13 fs 1300 nm driving pulses and simultaneous production of sub-5 fs pulses centered at 800 nm. Optimization of high harmonic generation in a long and dense gas medium yields a phot...

journal_title：Scientific reports

authors： Barreau L,Ross AD,Garg S,Kraus PM,Neumark DM,Leone SR

更新日期：2020-04-01 00:00:00

abstract：:In the present work, linoleic acid and oleic acid were isolated from Indonesian corn oil and palm oil and they were used to prepare monoacylglycerol derivatives as the antibacterial agent. Indonesian corn oil contains 57.74% linoleic acid, 19.88% palmitic acid, 11.84% oleic acid and 3.02% stearic acid. While Indonesia...

journal_title：Scientific reports

authors： Jumina J,Lavendi W,Singgih T,Triono S,Steven Kurniawan Y,Koketsu M

更新日期：2019-07-29 00:00:00

abstract：:Glomerular filtration rate (GFR) assessment is indicated before every administration of cisplatin. The optimal modality for this purpose [GFR measurement by urinary Creatinine Clearance (uCrCl) versus GFR estimation (eGFR) by the CKD-EPI formula versus both] is unclear. We investigated whether eGFR only is safe in thi...

journal_title：Scientific reports

authors： Klöckl MC,Kasparek AK,Riedl JM,Moik F,Mollnar S,Stotz M,Szkandera J,Terbuch A,Gerger A,Niedrist T,Pichler M,Bauernhofer T,Schilcher G,Zitta S,Rosenkranz AR,Friedl C,Stöger H,Posch F

更新日期：2020-07-08 00:00:00

abstract：:Anopheles gambiae and Aedes aegypti are perhaps the best studied mosquito species and important carriers of human malaria and arbovirus, respectively. Mosquitoes have daily rhythms in behaviors and show a wide range of activity patterns. Although Anopheles is known to be principally nocturnal and Aedes principally diu...

journal_title：Scientific reports

authors： Araujo MDS,Guo F,Rosbash M

更新日期：2020-03-19 00:00:00

abstract：:To evaluate the diagnostic accuracy of combined computed tomography colonography (CTC) and dual-energy iodine map imaging for detecting colorectal masses using high-pitch dual-source CT, compared with optical colonography (OC) and histopathologic findings. Twenty-eight consecutive patients were prospectively enrolled ...

journal_title：Scientific reports

authors： Sun K,Han R,Han Y,Shi X,Hu J,Lu B

更新日期：2018-02-28 00:00:00

abstract：:Glutamate dehydrogenase (GDH) is a key enzyme interlinking carbon and nitrogen metabolism. Recent discoveries of the GDH specific role in breast cancer, hyperinsulinism/hyperammonemia (HI/HA) syndrome, and neurodegenerative diseases have reinvigorated interest on GDH regulation, which remains poorly understood despite...

journal_title：Scientific reports

authors： Bera S,Rashid M,Medvinsky AB,Sun GQ,Li BL,Acquisti C,Sljoka A,Chakraborty A

更新日期：2020-10-05 00:00:00

abstract：:Hematopoietic stem cells (HSCs) maintain the entire blood system throughout life and are utilized in therapeutic approaches for blood diseases. Prospective isolation of highly purified HSCs is crucial to understand the molecular mechanisms underlying regulation of HSCs. The zebrafish is an elegant genetic model for th...

journal_title：Scientific reports

authors： Kobayashi I,Kondo M,Yamamori S,Kobayashi-Sun J,Taniguchi M,Kanemaru K,Katakura F,Traver D

更新日期：2019-10-02 00:00:00

abstract：:Werner syndrome (WS) is the canonical adult human progeroid ('premature aging') syndrome. Patients with this autosomal recessive Mendelian disorder display constitutional genomic instability and an elevated risk of important age-associated diseases including cancer. Remarkably few analyses of WS patient tissue and tum...

journal_title：Scientific reports

authors： Tokita M,Kennedy SR,Risques RA,Chun SG,Pritchard C,Oshima J,Liu Y,Bryant-Greenwood PK,Welcsh P,Monnat RJ

更新日期：2016-08-25 00:00:00

abstract：:We collected data from Kailuan cohort study from 2006 to 2011 to examine whether short-term effects of ambient temperature on heart rate (HR) and blood pressure (BP) are non-linear or linear, and their potential modifying factors. The HR, BP and individual information, including basic characteristics, life style, soci...

journal_title：Scientific reports

authors： Madaniyazi L,Zhou Y,Li S,Williams G,Jaakkola JJ,Liang X,Liu Y,Wu S,Guo Y

更新日期：2016-02-15 00:00:00

abstract：:Pesticides, including neonicotinoids, typically target pest insects by being neurotoxic. Inadvertent exposure to foraging insect pollinators is usually sub-lethal, but may affect cognition. One cognitive trait, spatial working memory, may be important in avoiding previously-visited flowers and other spatial tasks such...

journal_title：Scientific reports

authors： Samuelson EE,Chen-Wishart ZP,Gill RJ,Leadbeater E

更新日期：2016-12-13 00:00:00

abstract：:Metabolic syndrome (MS) and Framingham risk score (FRS) can be used for predicting the risk of developing cardiovascular diseases (CVD). Previous studies that compared FRS and MS have focused on high-income urban areas. This study focused on the comparison between FRS and MS when used in nomadic minorities in mountain...

journal_title：Scientific reports

authors： Yang W,Ma R,Zhang X,Guo H,He J,Mao L,Mu L,Hu Y,Yan Y,Liu J,Ma J,Li S,Ding Y,Zhang M,Zhang J,Guo S

更新日期：2018-11-07 00:00:00

abstract：:In the eyeblink conditioning paradigm, cerebellar Purkinje cells learn to respond to the conditional stimulus with an adaptively timed pause in its spontaneous firing. Evidence suggests that the pause is elicited by glutamate released from parallel fibers and acting on metabotropic receptors (mGluR7) which initiates a...

journal_title：Scientific reports

authors： Johansson F,Hesslow G

更新日期：2020-09-24 00:00:00

abstract：:Subcutaneous white adipose tissue (scWAT) is the major fat depot in humans and is a central player in regulating whole body metabolism. Skin exposure to UV wavelengths from sunlight is required for Vitamin D synthesis and pigmentation, although it is plausible that longer visible wavelengths that penetrate the skin ma...

journal_title：Scientific reports

authors： Ondrusova K,Fatehi M,Barr A,Czarnecka Z,Long W,Suzuki K,Campbell S,Philippaert K,Hubert M,Tredget E,Kwan P,Touret N,Wabitsch M,Lee KY,Light PE

更新日期：2017-11-27 00:00:00

abstract：:Considering the significance of mast cells (MCs) in the course of various physiological and pathological processes, and the pivotal role of endogenous molecules, i.e., cathelicidins and defensins as multifunctional modulators, the study examines the constitutive and cathelicidin LL-37/defensin hBD-2-induced expression...

journal_title：Scientific reports

authors： Agier J,Różalska S,Wiktorska M,Żelechowska P,Pastwińska J,Brzezińska-Błaszczyk E

更新日期：2018-08-06 00:00:00

abstract：:Polarization of macrophages is regulated through complex signaling networks. Correlating miRNA and mRNA expression over time after macrophage polarization has not yet been investigated. We used paired RNA-Seq and miRNA-Seq experiments to measure the mRNA and miRNA expression in bone marrow-derived macrophages over a t...

journal_title：Scientific reports

authors： Lu L,McCurdy S,Huang S,Zhu X,Peplowska K,Tiirikainen M,Boisvert WA,Garmire LX

更新日期：2016-12-16 00:00:00

abstract：:The development of artificial intelligence has led researchers to study the ethical principles that should guide machine behavior. The challenge in building machine morality based on people's moral decisions, however, is accounting for the biases in human moral decision-making. In seven studies, this paper investigate...

journal_title：Scientific reports

authors： Frank DA,Chrysochou P,Mitkidis P,Ariely D

更新日期：2019-09-11 00:00:00