Abstract:
:In the present work, linoleic acid and oleic acid were isolated from Indonesian corn oil and palm oil and they were used to prepare monoacylglycerol derivatives as the antibacterial agent. Indonesian corn oil contains 57.74% linoleic acid, 19.88% palmitic acid, 11.84% oleic acid and 3.02% stearic acid. While Indonesian palm oil contains 44.72% oleic acid, 39.28% palmitic acid, 4.56% stearic acid and 1.54% myristic acid. The oleic acid was purified by using Urea Inclusion Complex (UIC) method and its purity was significantly increased from 44.72% to 94.71%. Meanwhile, with the UIC method, the purity of ethyl linoleate was increased from 57.74% to 72.14%. 1-Monolinolein and 2-monoolein compounds were synthesized via two-step process from the isolated linoleic acid and oleic acid, respectively. The preliminary antibacterial assay shows that the 1-monolinolein did not give any antibacterial activity against Staphylococcus aureus and Escherichia coli, while 2-monoolein showed weak antibacterial activity against Staphylococcus aureus.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Jumina J,Lavendi W,Singgih T,Triono S,Steven Kurniawan Y,Koketsu Mdoi
10.1038/s41598-019-47373-4subject
Has Abstractpub_date
2019-07-29 00:00:00pages
10941issue
1issn
2045-2322pii
10.1038/s41598-019-47373-4journal_volume
9pub_type
杂志文章abstract::Genetically engineered mouse cancer models allow tumors to be imaged in vivo via co-expression of a reporter gene with a tumor-initiating gene. However, differential transcriptional and translational regulation between the tumor-initiating gene and the reporter gene can result in inconsistency between the actual tumor...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep08053
更新日期:2015-01-27 00:00:00
abstract::Pulse generation often requires a stabilized cavity and its corresponding mode structure for initial phase-locking. Contrastingly, modeless cavity-free random lasers provide new possibilities for high quantum efficiency lasing that could potentially be widely tunable spectrally and temporally. Pulse generation in rand...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep18526
更新日期:2015-12-21 00:00:00
abstract::Tick-borne diseases are the most common vector-borne diseases in the United States, with serology being the primary method of diagnosis. We developed the first multiplex, array-based assay for serodiagnosis of tick-borne diseases called the TBD-Serochip. The TBD-Serochip was designed to discriminate antibody responses...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-21349-2
更新日期:2018-02-16 00:00:00
abstract::The quantum mechanical motion of electrons and nuclei in systems spatially confined to the molecular dimensions occurs on the sub-femtosecond to the femtosecond timescales respectively. Consequently, the study of ultrafast electronic and, in specific cases, nuclear dynamics requires the availability of light pulses wi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-60331-9
更新日期:2020-02-28 00:00:00
abstract::The catalytic and optical properties of metal nanoparticles can be combined to create platforms for light-driven chemical energy storage and enhanced in-situ reaction monitoring. However, the heavily damped plasmon resonances of many catalytically active metals (e.g. Pt, Pd) prevent this dual functionality in pure nan...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep17431
更新日期:2015-11-30 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-61010-5
更新日期:2020-03-03 00:00:00
abstract::A number of studies have shown that visible and near infrared spectroscopy (VIS-NIRS) offers a rapid on-site measurement tool for the determination of total contaminant concentration of petroleum hydrocarbons compounds (PHC), heavy metals and metalloids (HM) in soil. However none of them have yet assessed the feasibil...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-41161-w
更新日期:2019-03-14 00:00:00
abstract::Previous studies have documented that decompression led to endothelial dysfunction with controversial results. This study aimed to clarify the relationship between endothelial dysfunction, bubble formation and decompression rate. Rats were subjected to simulated air dives with one of four decompression rates: one slow...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33390
更新日期:2016-09-12 00:00:00
abstract::Archaeologically defined Upper Palaeolithic (UP, 45,000-10,000 years ago) "cultures" are often used as proxies to designate fossil populations. While recent genomic studies have partly clarified the complex relationship between European UP "cultures" and past population dynamics, they leave open numerous questions reg...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-78841-x
更新日期:2020-12-14 00:00:00
abstract::Emergence of multiple drug resistant strains of pathogenic bacteria calls for new initiatives to combat infectious diseases. Gold nanoparticles (AuNPs), because of their non-toxic nature and size/shape dependent optical properties, offer interesting possibility. Here we report the antibacterial efficacy of AuNPs of di...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09357-0
更新日期:2017-08-29 00:00:00
abstract::The association between cervical lymph node metastasis (LNM) and ultrasonographic features as well as BRAFV600E mutations in patients with papillary thyroid carcinoma (PTC) remained controversial. This study investigated the association between LNM and ultrasonographic features as well as BRAFV600E mutation in Chinese...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36171-z
更新日期:2019-01-11 00:00:00
abstract::The biodosimetric information is critical for evaluating the human health hazards caused by radon and its progeny. Here, we demonstrated that the formation of phosphorylated histone variant H2AX (γ-H2AX), p53-binding protein 1 (53BP1) and phosphorylated KRAB-associated protein 1 (pKAP-1) foci and their linear tracks i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep38295
更新日期:2016-12-06 00:00:00
abstract::Bone tissues have trabecular bone with a high bone turnover and cortical bone with a low turnover. The mechanisms by which the turnover rate of these bone tissues is determined remain unclear. Osteocytes secrete sclerostin, a Wnt/β-catenin signaling antagonist, and inhibit bone formation. We found that sclerostin expr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-70817-1
更新日期:2020-08-13 00:00:00
abstract::In this study, real-time and in-situ permittivity measurements under intense microwave electromagnetic fields are proposed as a powerful technique for the study of microwave-enhanced thermal processes in materials. In order to draw reliable conclusions about the temperatures at which transformations occur, we address ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-47296-0
更新日期:2019-07-25 00:00:00
abstract::Rice lines with slower starch digestibility provide opportunities in mitigating the global rise in type II diabetes and related non-communicable diseases. However, screening for low glycemic index (GI) in rice breeding programs is not possible due to time and cost constraints. This study evaluated the feasibility of u...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06026-0
更新日期:2017-07-19 00:00:00
abstract::Innate immunity has been extended to respond environmental pathogen other than microbial components. Here we explore a novel pollen/TLR4 innate immunity in allergic inflammation. In experimental allergic conjunctivitis induced by short ragweed (SRW) pollen, typical allergic signs, stimulated IL-33/ST2 signaling and ov...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep36150
更新日期:2016-10-31 00:00:00
abstract::Clostridial neurotoxins (CNTs), which include botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT), are the most potent toxins known to science and are the causative agents of botulism and tetanus, respectively. The evolutionary origins of CNTs and their relationships to other proteins remains an intriguing que...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-37647-8
更新日期:2019-02-07 00:00:00
abstract::The kidney is a high-energy demand organ rich in mitochondria especially renal tubular cells. Emerging evidence suggests that mitochondrial dysfunction, redox imbalance and kidney injury are interconnected. Artemether has biological effects by targeting mitochondria and exhibits potential therapeutic value for kidney ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80298-x
更新日期:2021-01-14 00:00:00
abstract::Despite the tremendous progress of quantum cryptography, efficient quantum communication over long distances (≥ 1000 km) remains an outstanding challenge due to fiber attenuation and operation errors accumulated over the entire communication distance. Quantum repeaters (QRs), as a promising approach, can overcome both...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep20463
更新日期:2016-02-15 00:00:00
abstract::Gene selection is an attractive and important task in cancer survival analysis. Most existing supervised learning methods can only use the labeled biological data, while the censored data (weakly labeled data) far more than the labeled data are ignored in model building. Trying to utilize such information in the censo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-13133-5
更新日期:2017-10-12 00:00:00
abstract::The sweetpotato whitefly Bemisia tabaci (Gennadius) was challenged with different combinations of matrine (insecticide) and Lecanicillium muscarium (entomopathogenic fungus). Our results revealed a synergistic relationship between matrine and L. muscarium on mortality and enzyme activities of B. tabaci. To illustrate ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46558
更新日期:2017-04-20 00:00:00
abstract::The increase in antibiotic resistant bacteria has raised global concern regarding the future effectiveness of antibiotics. Human activities that influence microbial communities and environmental resistomes can generate additional risks to human health. In this work, we characterized aquatic microbial communities and t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-48200-6
更新日期:2019-08-13 00:00:00
abstract::Thin waveguides such as graded-index lenses and fiber bundles are often used as imaging probes for high-resolution endomicroscopes. However, strong back-reflection from the end surfaces of the probes makes it difficult for them to resolve weak contrast objects, especially in the reflectance-mode imaging. Here we propo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-07024-y
更新日期:2017-07-26 00:00:00
abstract::Flexible thermoelectric generators (TEGs) can provide uninterrupted, green energy from body-heat, overcoming bulky battery configurations that limit the wearable-technologies market today. High-throughput production of flexible TEGs is currently dominated by printing techniques, limiting material choices and performan...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-41000-y
更新日期:2019-03-13 00:00:00
abstract::Human induced pluripotent stem cells (hiPSCs) are expected to be both a revolutionary cell source for regenerative medicine and a powerful tool to investigate the molecular mechanisms underlying human cell development in vitro. In the present study, we tried to elucidate the steroidogenic differentiation processes usi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-15485-4
更新日期:2017-11-09 00:00:00
abstract::Cardiac lipotoxicity is involved in the cardiac functional consequences associated with obesity. Therefore, the aim of this study was to explore whether changes in the mitochondrial lipid cardiac profile could reflect differences in cardiac function and structure in obese and non-obese rats with myocardial infarction ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36914-y
更新日期:2019-01-24 00:00:00
abstract::Genome engineering is a rapidly evolving field that benefits from the availability of different tools that can be used to perform genome manipulation tasks. We describe here the development of the Flp-TAL recombinases that can target genomic FRT-like sequences in their native chromosomal locations. Flp-TAL recombinase...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-74474-2
更新日期:2020-10-15 00:00:00
abstract::Idiopathic pulmonary fibrosis (IPF) is a progressive disease characterized by interstitial remodeling and pulmonary dysfunction. The etiology of IPF is not completely understood but involves pathologic inflammation and subsequent failure to resolve fibrosis in response to epithelial injury. Treatments for IPF are limi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-68336-0
更新日期:2020-07-15 00:00:00
abstract::The Thoroughbred horse has played an important role in both sporting and economic aspects of society since the establishment of the breed in the 1700s. The extensive pedigree and phenotypic information available for the Thoroughbred horse population provides a unique opportunity to examine the effects of 300 years of ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-24663-x
更新日期:2018-04-18 00:00:00
abstract::Liquid repellent surfaces typically work by keeping the fouling liquid in a metastable state, with trapped pockets of air between the substrate and the liquid. An alternative method with greater long-term stability utilizes liquid-impregnated surfaces, where the liquid being repelled slides over an immiscible liquid i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06621-1
更新日期:2017-07-20 00:00:00