Abstract：
:Astaxanthin is a ketocarotenoid produced by photosynthetic microalgae. It is a pigment of high industrial interest in acquaculture, cosmetics, and nutraceutics due to its strong antioxidant power. Haematococcus pluvialis, a fresh-water microalga, accumulates high levels of astaxanthin upon oxidative stress, reaching values up to 5% per dry weight. H. pluvialis accumulates astaxanthin in oil droplets in the cytoplasm, while the chloroplast volume is reduced. In this work, we investigate the biochemical and spectroscopic properties of the H. pluvialis pigment binding complexes responsible for light harvesting and energy conversion. Our findings demonstrate that the main features of chlorophyll and carotenoid binding complexes previously reported for higher plants or Chlamydomonas reinhardtii are preserved under control conditions. Transition to astaxanthin rich cysts however leads to destabilization of the Photosystems. Surprisingly, astaxanthin was found to be bound to both Photosystem I and II, partially substituting β-carotene, and thus demonstrating possible astaxanthin biosynthesis in the plastids or transport from the cytoplasm to the chloroplast. Astaxanthin binding to Photosystems does not however improve their photoprotection, but rather reduces the efficiency of excitation energy transfer to the reaction centers. We thus propose that astaxanthin binding partially destabilizes Photosystem I and II.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Mascia F,Girolomoni L,Alcocer MJP,Bargigia I,Perozeni F,Cazzaniga S,Cerullo G,D'Andrea C,Ballottari Mdoi
10.1038/s41598-017-16641-6subject
Has Abstractpub_date
2017-11-24 00:00:00pages
16319issue
1issn
2045-2322pii
10.1038/s41598-017-16641-6journal_volume
7pub_type
杂志文章abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-57442-8
更新日期：2020-01-15 00:00:00
abstract：:Bovine lactoferrin is a biglobular multifunctional iron binding glycoprotein that plays an important role in innate immunity against infections. We have previously demonstrated that selected peptides from bovine lactoferrin C-lobe are able to prevent both Influenza virus hemagglutination and cell infection. To deeper ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-10492-x
更新日期：2017-09-06 00:00:00
abstract：:It is common to find in the literature different values for the working voltage window (WVW) range for aqueous-based supercapacitors. In many cases, even with the best intentions of the widening the operating voltage window, the measured current using the cyclic voltammetry (CV) technique includes a significant contri...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-75851-7
更新日期：2020-11-05 00:00:00
abstract：:Reducing black carbon (BC), i.e. soot, in the atmosphere is a potential mitigation measure for climate change before revealing the effect of reducing anthropogenic carbon dioxide (CO2) because BC with shorter lifetime than CO2 absorbs solar and infrared radiation. BC has a strong positive radiative forcing in the atmo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-41181-6
更新日期：2019-03-14 00:00:00
abstract：:Hatching out from the zona pellucida (ZP) is a crucial step for blastocyst implantation and development. However, it is still unknown whether the location of the hatching site relative to the inner cell mass (ICM) affects embryo implantation and foetal development. Here, we classified hatching blastocysts into three c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-59424-2
更新日期：2020-02-12 00:00:00
abstract：:A variety of animals use Earth's magnetic field as a reference for their orientation behaviour. Although distinctive magnetoreception mechanisms have been postulated for many migrating or homing animals, the molecular mechanisms are still undefined. In this study, we found that zebrafish, a model organism suitable for...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep00727
更新日期：2012-01-01 00:00:00
abstract：:In the present study, we obtained population genetic data and forensic parameters of 30 InDel loci in Chinese Xibe ethnic group from northwestern China and studied the genetic relationships between the studied Xibe group and other reference groups. The observed heterozygosities ranged from 0.1704 at HLD118 locus to 0....
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep08260
更新日期：2015-02-05 00:00:00
abstract：:A larger amount of sequence data in private and public databases produced by next-generation sequencing put new challenges due to limitation associated with the alignment-based method for sequence comparison. So, there is a high need for faster sequence analysis algorithms. In this study, we developed an alignment-fre...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-40452-6
更新日期：2019-03-06 00:00:00
abstract：:Robust biomarker quantification is essential for the accurate diagnosis of diseases and is of great value in cancer management. In this paper, an innovative diagnostic platform is presented which provides automated molecularly imprinted solid-phase extraction (MISPE) followed by liquid chromatography-mass spectrometry...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep44298
更新日期：2017-03-17 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-74319-y
更新日期：2020-10-28 00:00:00
abstract：:CRISPR/Cas9-derived RNA-guided nucleases (RGNs) are DNA targeting systems, which are rapidly being harnessed for gene regulation and gene editing purposes in model organisms and cell lines. As bona fide gene delivery vehicles, viral vectors may be particularly fit to broaden the applicability of RGNs to other cell typ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep05105
更新日期：2014-05-29 00:00:00
abstract：:Ferritin has gained significant attention as a potential reporter gene for in vivo imaging by magnetic resonance imaging (MRI). However, due to the ferritin ferrihydrite core, the relaxivity and sensitivity for detection of native ferritin is relatively low. We report here on a novel chimeric magneto-ferritin reporter...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep26550
更新日期：2016-05-23 00:00:00
abstract：:Triboelectric charging is common in desert sandstorms and dust devils on Earth; however, it remains poorly understood. Here we show a charging mechanism of sands with the adsorbed water on micro-porous surface in wind-blown sand based on the fact that water content is universal but usually a minor component in most pa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01337
更新日期：2013-01-01 00:00:00
abstract：:Marek's disease virus (MDV) is a highly cell-associated alphaherpesvirus that causes deadly lymphomas in chickens. While vaccination protects against clinical symptoms, MDV field strains can still circulate in vaccinated flocks and continuously evolve towards greater virulence. MDV vaccines do not provide sterilizing ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-67951-1
更新日期：2020-07-02 00:00:00
abstract：:A host of hormonal-metabolic alterations take place following exposure of cardiomyocytes to hypoxia and other noxious stimuli. Here, we demonstrate that exposure of cultured rat cardiomyocytes to lipopolysaccharide (LPS) resulted in upregulation (~1.5 fold) of oxidized low-density lipoprotein receptor-1 (LOX-1). There...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-55694-7
更新日期：2019-12-17 00:00:00
abstract：:Recent increases in family planning (FP) use have been reported among women of reproductive age in union (WRAU) in Senegal. However, trends have not been monitored among harder-to-reach groups (including adolescents, unmarried and rural poor women), key to understanding whether FP progress is equitable. We combined da...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep41006
更新日期：2017-01-20 00:00:00
abstract：:Chronic inflammation-associated bone destruction, which is observed in rheumatoid arthritis (RA) and periodontitis, is mediated by excessive osteoclastogenesis. We showed previously that γ-glutamyltranspeptidase (GGT), an enzyme involved in glutathione metabolism, acts as an endogenous activator of such pathological o...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35930
更新日期：2016-10-24 00:00:00
abstract：:We report on a highly efficient magneto-actuated cancer cell apoptosis method using a biaxial pulsed magnetic field configuration, which maximizes the induced magnetic torque. The light transmissivity dynamics show that the biaxial magnetic field configuration can actuate the magnetic nanoparticles with higher respons...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-11279-w
更新日期：2017-09-07 00:00:00
abstract：:Organic nanofibers have found various applications in optoelectronic devices. In such devices, exciton diffusion is a major aspect concerning their efficiency. In the case of singlet excitons, Förster transfer is the mechanism responsible for this process. Temperature and morphology are factors known to influence exci...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-32232-5
更新日期：2018-09-19 00:00:00
abstract：:CRISPR-Cas9/gRNA exhibits therapeutic efficacy against latent human immunodeficiency virus (HIV) genome but the delivery of this therapeutic cargo to the brain remains as a challenge. In this research, for the first time, we demonstrated magnetically guided non-invasive delivery of a nano-formulation (NF), composed of...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-40222-4
更新日期：2019-03-08 00:00:00
abstract：:During dental erosion, tooth minerals are dissolved, leading to a softening of the surface and consequently to irreversible surface loss. Components from human saliva form a pellicle on the tooth surface, providing some protection against erosion. To assess the effect of different components and compositions of saliva...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep34760
更新日期：2016-10-05 00:00:00
abstract：:Drosophila melanogaster is a promiscuous species that inhabits a large range of harsh environments including flooded habitats and varying temperature changes. To survive these environments, fruit flies have adapted mechanisms of tolerance that allow them to thrive. During exposure to anoxic stress, fruit flies and oth...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep09204
更新日期：2015-03-17 00:00:00
abstract：:Powdery mildew, a common cereal disease caused by the fungus Blumeria graminis, is a major limiting factor of barley production and genetic resistance is the most appropriate protection against it. To aid the breeding of new cultivars and their marketing, resistance genes can be postulated in homogeneous accessions. A...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-75978-7
更新日期：2020-11-03 00:00:00
abstract：:The G-protein coupled, protease-activated receptor 1 (PAR1) is a membrane protein expressed in astrocytes. Fine astrocytic processes are in tight contact with neurons and blood vessels and shape excitatory synaptic transmission due to their abundant expression of glutamate transporters. PAR1 is proteolytically-activat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep43606
更新日期：2017-03-03 00:00:00
abstract：:Graphene, a honeycomb lattice of carbon atoms ruled by tight-binding interaction, exhibits extraordinary electronic properties due to the presence of Dirac cones within its band structure. These intriguing singularities have naturally motivated the discovery of their classical analogues. In this work, we present a gen...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-15335-3
更新日期：2017-11-10 00:00:00
abstract：:The introduced oriental shrimp Palaemon macrodactylus has recently become widespread in temperate estuaries worldwide. However, this recent worldwide spread outside of its native range arises after a previous introduction to the US Pacific coast, where it was restricted for more than 30 years. Using a phylogeographic ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep05808
更新日期：2014-07-24 00:00:00
abstract：:In a large German community sample of adults, we investigated the association of chronic anxiousness with cardiovascular disease and mortality. Self-reported anxiousness from 11,643 German adults between 40 and 80 years of age from the Gutenberg Health Study (GHS) was analyzed over 5 years. Multivariable regression mo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69427-8
更新日期：2020-07-24 00:00:00
abstract：:Charge noise is critical in the performance of gate-controlled quantum dots (QDs). Such information is not yet available for QDs made out of the new material graphene, where both substrate and edge states are known to have important effects. Here we show the 1/f noise for a microscopic graphene QD is substantially lar...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep08142
更新日期：2015-01-30 00:00:00
abstract：:Microbial life below the seafloor has changed over geological time, but these changes are often not obvious, as they are not recorded in the sediment. Sulphur (S) isotope values in pyrite extracted from a Plio- to Holocene sequence of the Peru Margin (Ocean Drilling Program, ODP, Site 1229) show a down-core pattern th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-36943-7
更新日期：2019-01-24 00:00:00
abstract：:The macrophage migration inhibitory factor (MIF) is a cytokine that plays an important role in inhibiting the growth of pathogenic Mycobacterium tuberculosis (M.tb) and regulates immune responses against M.tb pathogen. MIF -173 G > C gene polymorphism may affect immunity in an individual and leads to susceptibility to...
journal_title：Scientific reports
pub_type： 杂志文章,meta分析
doi：10.1038/s41598-017-17308-y
更新日期：2017-12-05 00:00:00
