Abstract:
:Recent increases in family planning (FP) use have been reported among women of reproductive age in union (WRAU) in Senegal. However, trends have not been monitored among harder-to-reach groups (including adolescents, unmarried and rural poor women), key to understanding whether FP progress is equitable. We combined data from six Demographic and Health Surveys conducted in Senegal between 1992/93 and 2014. We examined FP trends over time among WRAU and subgroups, and trends in knowledge of FP and intention to use among women with unmet need for FP. Our results show that percent demand satisfied is lower among rural poor women and adolescents than WRAU, although higher among unmarried women. Marked recent increases have been observed in all subgroups, however fewer than 50% of women in need of FP use modern contraception in Senegal. Knowledge of FP has risen steadily among women with unmet need; however, intention to use FP has remained stable at around 40% since 2005 for all groups except unmarried women (75% of whom intend to use). Significant progress in meeting the need for FP has been achieved in Senegal, but more needs to be done particularly to improve acceptability of FP, and to strategically target interventions toward adolescents and rural poor women.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Cavallaro FL,Benova L,Macleod D,Faye A,Lynch CAdoi
10.1038/srep41006subject
Has Abstractpub_date
2017-01-20 00:00:00pages
41006issn
2045-2322pii
srep41006journal_volume
7pub_type
杂志文章abstract::Physical reservoir computing approaches have gained increased attention in recent years due to their potential for low-energy high-performance computing. Despite recent successes, there are bounds to what one can achieve simply by making physical reservoirs larger. Therefore, we argue that a switch from single-reservo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-71549-y
更新日期:2020-09-02 00:00:00
abstract::Transcription factors (TFs) binding to specific DNA sequences or motifs, are elementary to the regulation of transcription. The gene is regulated by a combination of TFs in close proximity. Analysis of co-TFs is an important problem in understanding the mechanism of transcriptional regulation. Recently, ChIP-seq in ma...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43597
更新日期:2017-02-27 00:00:00
abstract::Chronic myeloid leukemia (CML) is characterized in the majority of cases by a t(9;22)(q34;q11) translocation, also called the Philadelphia chromosome, giving rise to the BCR-ABL1 fusion protein. Current treatment with tyrosine kinase inhibitors is directed against the constitutively active ABL1 domain of the fusion pr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00755-y
更新日期:2017-04-04 00:00:00
abstract::Amyloid precursor protein (APP) and its cleavage product amyloid β (Aβ) have been thoroughly studied in Alzheimer's disease. However, APP also appears to be important for neuronal development. Differentiation of induced pluripotent stem cells (iPSCs) towards cortical neurons enables in vitro mechanistic studies on hum...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29200
更新日期:2016-07-07 00:00:00
abstract::The prion protein (PrP) evolved from the subbranch of ZIP metal ion transporters comprising ZIPs 5, 6 and 10, raising the prospect that the study of these ZIPs may reveal insights relevant for understanding the function of PrP. Building on data which suggested PrP and ZIP6 are critical during epithelial-to-mesenchymal...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40313
更新日期:2017-01-18 00:00:00
abstract::Dendritic spines are the postsynaptic sites of most excitatory synapses in the brain, and spine enlargement and shrinkage give rise to long-term potentiation and depression of synapses, respectively. Because spine structural plasticity is accompanied by remodeling of actin scaffolds, we hypothesized that the filamento...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep32897
更新日期:2016-09-06 00:00:00
abstract::Singlet oxygen (1O2) is a type of reactive oxygen species involved in numerous physiological activities. We previously reported that 1O2-specific oxidation products are increased in patients with prediabetes, suggesting that measurement of 1O2 may be an important indicator of physiological and pathological conditions....
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-67155-7
更新日期:2020-06-30 00:00:00
abstract::It has been reported that non-selective autophagy of infected hepatocytes could facilitate the development of malaria in the liver stage, but the fate of parasites following selective autophagy of infected hepatocytes is still not very clear. Here, we confirmed that sporozoite infection can induce a selective autophag...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep38170
更新日期:2016-11-30 00:00:00
abstract::Within the last fifteen years, network theory has been successfully applied both to natural sciences and to socioeconomic disciplines. In particular, bipartite networks have been recognized to provide a particularly insightful representation of many systems, ranging from mutualistic networks in ecology to trade networ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep10595
更新日期:2015-06-01 00:00:00
abstract::Although increases in cardiovascular load (pressure overload) are known to elicit ventricular remodeling including cardiomyocyte hypertrophy and interstitial fibrosis, the molecular mechanisms of pressure overload or AngII -induced cardiac interstitial fibrosis remain elusive. In this study, serpinE2/protease nexin-1 ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37635
更新日期:2016-11-23 00:00:00
abstract::We show that through the wave energy conserved and reversible process of coherent interactions of scalar waves in a multi-channel system joint by a common junction, it is possible to generate outgoing waves only in certain channels by controlling the incoming waves. We refer to such processes as coherent perfect chann...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-14422-9
更新日期:2017-10-24 00:00:00
abstract::MicroRNA is responsible for the fine-tuning of fundamental cellular activities and human disease development. The altered availability of microRNAs, target mRNAs, and other types of endogenous RNAs competing for microRNA interactions reflects the dynamic and conditional property of microRNA-mediated gene regulation th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-13470-5
更新日期:2017-10-17 00:00:00
abstract::Secondary thrombocytosis (ST) is frequently observed in children with a variety of clinical conditions. The leading cause of ST is respiratory tract infection (RTI) in children. Nasopharyngeal aspirate samples were collected and assessed for common respiratory viruses. The relationships between virus infections and se...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep22964
更新日期:2016-03-11 00:00:00
abstract::In this work, we address the ubiquitous phenomenon of Fano resonances in bilayer graphene. We consider that this phenomenon is as exotic as other phenomena in graphene because it can arise without an external extended states source or elaborate nano designs. However, there are not theoretical and/or experimental studi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-16838-9
更新日期:2017-12-01 00:00:00
abstract::Diamond attracts considerable attention as a versatile and technologically useful material. For many demanding applications, such as recently emerged quantum optics and sensing, it is important to develop new routes for fabrication of diamond containing defects with specific optical, electronic and magnetic properties...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep14789
更新日期:2015-10-05 00:00:00
abstract::This paper investigates the possibility of saving a network that is predicted to have a cascading failure that will eventually lead to a total collapse. We model cascading failures using the recently proposed KQ model. Then predict an impending total collapse by monitoring critical slowing down indicators and subseque...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-25591-6
更新日期:2018-05-10 00:00:00
abstract::Least component-based delivery of drug-tagged-nanocarriers across blood-brain-barriers (BBB) will allow site-specific and on-demand release of therapeutics to prevent CNS diseases. We developed a non-invasive magnetically guided delivery of magneto-electric nanocarriers (MENCs), ~20 nm, 10 mg/kg, across BBB in C57Bl/J...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25309
更新日期:2016-05-04 00:00:00
abstract::Histone lysine acetyltransferase (KAT)-catalyzed acetylation of lysine residues in histone tails plays a key role in regulating gene expression in eukaryotes. Here, we examined the role of lysine side chain length in the catalytic activity of human KATs by incorporating shorter and longer lysine analogs into synthetic...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-69510-0
更新日期:2020-08-03 00:00:00
abstract::Oligomannose-type glycans on HIV-1 gp120 form a patch that is targeted by several broadly neutralizing antibodies (bnAbs) and that therefore is of interest to vaccine design. However, attempts to elicit similar oligomannose-specific bnAbs by immunizing with oligomannosidic glycoconjugates have only been modestly succe...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-64500-8
更新日期:2020-05-05 00:00:00
abstract::The anti-diabetic biguanide drugs metformin (METF) and phenformin (PHEN) may have anti-cancer effects. Biguanides suppress plasma growth factors, but nonetheless, the view that these mitochondrial inhibitors accumulate in tumor tissue to an extent that leads to severe energetic stress or alleviation of hypoxia-induced...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-10010-z
更新日期:2017-08-25 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-018-35437-w
更新日期:2018-11-22 00:00:00
abstract::Synthesis of homogenous glycans in quantitative yields represents a major bottleneck to the production of molecular tools for glycoscience, such as glycan microarrays, affinity resins, and reference standards. Here, we describe a combined biological/enzymatic synthesis that is capable of efficiently converting microbi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-15891-8
更新日期:2017-11-21 00:00:00
abstract::We utilized size-tunable gold nanoparticles (Au NPs) to investigate the toxicogenomic responses of the model organism Caenorhabditis elegans. We demonstrated that the nematode C. elegans can uptake Au NPs coated with or without 11-mercaptoundecanoic acid (MUA), and Au NPs are detectable in worm intestines using X-ray ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-33585-7
更新日期:2018-10-15 00:00:00
abstract::The weak correlation between pain and structural changes in knee osteoarthritis is widely reported. In a previous within-person, knee-matched case-control study among Caucasians, the severity of radiographic osteoarthritis (ROA) was strongly associated with both the presence of frequent knee pain and pain severity. We...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-19470-3
更新日期:2018-01-22 00:00:00
abstract::Recent studies have linked appearance of Paneth cells in colorectal adenomas to adenoma burden and male gender. However, the clinical importance of Paneth cells' associations with synchronous advanced adenoma (AA) and colorectal carcinoma (CRC) is currently unclear. We performed a comprehensive case-control study usin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep26129
更新日期:2016-05-18 00:00:00
abstract::Export of messenger ribonucleic acids (mRNAs) into the cytoplasm is a fundamental step in gene regulation processes, which is meticulously quality controlled by highly efficient mechanisms in eukaryotic cells. Yet, it remains unclear how the aberrant mRNAs are recognized and retained inside the nucleus. Using a new mo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep35380
更新日期:2016-11-02 00:00:00
abstract::Evaluations of restoration success usually focus on the structural aspects of ecosystems. Pollination, as an important functional aspect, is often overlooked. Here, the shifts in pollinator assemblage and pollen limitation in the desert shrub Caragana microphylla were examined along a restoration gradient in Horqin Sa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-17253-w
更新日期:2017-12-04 00:00:00
abstract::Maternal obesity and overnutrition during pregnancy and lactation can program an increased risk of obesity in offspring. In this context, improving maternal metabolism may help reduce the intergenerational transmission of obesity. Here we show that, in Sprague-Dawley rats, selectively altering obese maternal gut micro...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep20683
更新日期:2016-02-12 00:00:00
abstract::Bisphenol A (BPA), a member of the environmental endocrine disruptors (EDCs), has recently received increased attention because of its effects on brain insulin resistance. Available data have indicated that brain insulin resistance may contribute to neurodegenerative diseases. However, the associated mechanisms that u...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-07544-7
更新日期:2017-08-08 00:00:00
abstract::The ongoing global intensification of wheat production will likely be accompanied by a rising pressure of Fusarium diseases. While utmost attention was given to Fusarium head blight (FHB) belowground plant infections of the pathogen have largely been ignored. The current knowledge about the impact of soil borne Fusari...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-31544-w
更新日期:2018-09-03 00:00:00