Abstract：
:During dental erosion, tooth minerals are dissolved, leading to a softening of the surface and consequently to irreversible surface loss. Components from human saliva form a pellicle on the tooth surface, providing some protection against erosion. To assess the effect of different components and compositions of saliva on the protective potential of the pellicle against enamel erosion, we prepared four different kinds of saliva: human whole stimulated saliva (HS), artificial saliva containing only ions (AS), human saliva dialysed against artificial saliva, containing salivary proteins and ions (HS/AS), and human saliva dialysed against deionised water, containing only salivary proteins but no ions (HS/DW). Enamel specimens underwent four cycles of immersion in either HS, AS, HS/AS, HS/DW, or a humid chamber (Ctrl), followed by erosion with citric acid. During the cycling process, the surface hardness and the calcium released from the surface of the specimens were measured. The different kinds of saliva provided different levels of protection, HS/DW exhibiting significantly better protection than all the other groups (p < 0.0001). Different components of saliva, therefore, have different effects on the protective properties of the pellicle and the right proportions of these components in saliva are critical for the ability to form a protective pellicle.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Baumann T,Kozik J,Lussi A,Carvalho TSdoi
10.1038/srep34760subject
Has Abstractpub_date
2016-10-05 00:00:00pages
34760issn
2045-2322pii
srep34760journal_volume
6pub_type
杂志文章abstract：:Nuclear factor κB (NF-κB) plays an essential role in regulation of innate immunity. In mammals, NF-κB factors can form homodimers and heterodimers to activate gene expression. In insects, three NF-κB factors, Dorsal, Dif and Relish, have been identified to activate antimicrobial peptide (AMP) gene expression. However,...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep20654
更新日期：2016-02-05 00:00:00
abstract：:WRINKLED1 (WRI1), an APETALA2 (AP2)-type transcription factor, has been shown to be required for the regulation of carbon partitioning into fatty acid (FA) synthesis in plant seeds. To our knowledge, the regulatory network of WRI1 remains unknown in Prunus sibirica kernel (PSK), a novel woody biodiesel feedstock in Ch...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-39236-9
更新日期：2019-02-25 00:00:00
abstract：:Supercontinuum generation in Kerr media has become a staple of nonlinear optics. It has been celebrated for advancing the understanding of soliton propagation as well as its many applications in a broad range of fields. Coherent spectral broadening of laser light is now commonly performed in laboratories and used in c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-34344-4
更新日期：2018-11-21 00:00:00
abstract：:Probing the cellular structure of in vivo biological tissue is a fundamental problem in biomedical imaging and medical science. This work introduces an approach for analyzing diffusion magnetic resonance imaging data acquired by the novel tensor-valued encoding technique for characterizing tissue microstructure. Our a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-79748-3
更新日期：2021-01-08 00:00:00
abstract：:Angiopoietin-1 (Ang1) and Angiopoietin-2 (Ang2) are ligands for Tie2, an endothelial-specific receptor tyrosine kinase that is an essential regulator of angiogenesis. Here we report the identification, via expression cloning, of thrombomodulin (TM) as another receptor for Ang1 and Ang2. Thrombomodulin is an endothelia...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-18912-8
更新日期：2018-01-11 00:00:00
abstract：:A large amount of energy, perhaps twice the total amount of all other hydrocarbon reserves combined, is trapped within gas hydrate deposits. Despite emerging as a potential energy source for the world over the next several hundred years and one of the key factors in causing future climate change, gas hydrate is poorly...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-06717-8
更新日期：2017-07-25 00:00:00
abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-019-39693-2
更新日期：2019-04-17 00:00:00
abstract：:Increasing grain zinc (Zn) concentration of cereals for minimizing Zn malnutrition in two billion people represents an important global humanitarian challenge. Grain Zn in field-grown wheat at the global scale ranges from 20.4 to 30.5 mg kg-1, showing a solid gap to the biofortification target for human health (40 mg ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-07484-2
更新日期：2017-08-01 00:00:00
abstract：:Using the Ermakov-Lewis invariants appearing in KvN mechanics, the time-dependent frequency harmonic oscillator is studied. The analysis builds upon the operational dynamical model, from which it is possible to infer quantum or classical dynamics; thus, the mathematical structure governing the evolution will be the sa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-26759-w
更新日期：2018-05-30 00:00:00
abstract：:The role of marginal populations for the long-term maintenance of species' genetic diversity and evolutionary potential is particularly timely in view of the range shifts caused by climate change. The Centre-Periphery hypothesis predicts that marginal populations should bear reduced genetic diversity and have low evol...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep42416
更新日期：2017-02-10 00:00:00
abstract：:Higher and lower levels of alertness typically lead to a leftward and rightward bias in attention, respectively. This relationship between alertness and spatial attention potentially has major implications for health and safety. The current study examined alertness and spatial attention under simulated shiftworking co...
journal_title：Scientific reports
pub_type： 临床试验,杂志文章
doi：10.1038/s41598-020-71800-6
更新日期：2020-09-11 00:00:00
abstract：:Antiretroviral therapy-naive HIV-1 infected infants experience poor viral containment and rapid disease progression compared to adults. Viral factors (e.g. transmitted cytotoxic T- lymphocyte (CTL) escape mutations) or infant factors (e.g. reduced CTL functional capacity) may explain this observation. We assessed CTL ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep29536
更新日期：2016-07-12 00:00:00
abstract：:Scrophularia striata, commonly known as figwort, is one of the most important medicinal plants that mainly grows in cold regions of the Zagros Mountains (West of Iran). Although the chemical composition of this plant species has not yet been explored, people living in Ilam province (W Iran) have used it for many years...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-52605-8
更新日期：2019-11-05 00:00:00
abstract：:Although early diagnosis and treatment reduce the risk of blindness from glaucoma, the decision on whether or not to begin treatment in patients with suspected glaucoma is often a dilemma because the majority of patients never develop definite glaucoma. A growing body of evidences suggests that posterior bowing of the...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-17843-8
更新日期：2018-01-15 00:00:00
abstract：:The pathophysiological actions of fatty acids (FAs) on Alzheimer's disease (AD), which are possibly mediated by genomic effects, are widely known; however, their non-genomic actions remain elusive. The aim of this study was to investigate the non-genomic mechanism of extra-cellular palmitic acid (PA) regulating beta-a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-04175-w
更新日期：2017-06-28 00:00:00
abstract：:Most dogs worldwide are free-ranging animals that form relationships mainly with conspecifics, yet research has focused mainly on the dog-human bond, leading to the hypothesis that dogs evolved specific abilities to form a unique relationship with humans. Although widespread, this hypothesis has not, as yet, been test...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-40164-x
更新日期：2019-03-05 00:00:00
abstract：:Arrays of sub-wavelength, sub-10 nm air-gap plasmonic ring resonators are fabricated using nanoimprinting. In near infra-red (NIR) range, the resonator supports a single dipole mode which is excited and identified via simple normal illumination and explored through transmission measurements. By controlling both latera...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep22305
更新日期：2016-02-29 00:00:00
abstract：:We construct two families of orthogonal product quantum states that cannot be exactly distinguished by local operation and classical communication (LOCC) in the quantum system of (2k+i) ⊗ (2l+j) (i, j ∈ {0, 1} and i ≥ j ) and (3k+i) ⊗ (3l+j) (i, j ∈ {0, 1, 2}). And we also give the tiling structure of these two famili...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep28864
更新日期：2016-07-05 00:00:00
abstract：:The therapeutic potential of nonthermal plasma for cancer treatment has been reported recently. The heterogeneity of cancer cells need to be addressed to design effective anticancer treatments. Here, we show that treatment with nonthermal atmospheric-pressure plasma dissolved in a liquid (liquid plasma) induces oxidat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep29020
更新日期：2016-07-01 00:00:00
abstract：:Hearing loss becomes increasingly common with age and affects quality of life. Recently, scientists have published articles about the relationship between metabolic disease and hearing loss. Metabolic disease was previously found to be highly related to an increase in alkaline phosphatase. Thus, there may be an indire...
journal_title：Scientific reports
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1038/s41598-020-60979-3
更新日期：2020-03-04 00:00:00
abstract：:When searching for food, foraging fishes expose themselves to hidden predators. The strategies that maximize the survival of foraging fishes are not well understood. Here, we describe a novel type of mobbing behaviour displayed by foraging Scolopsis affinis. The fish direct sharp water jets towards the hidden sessile ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep33187
更新日期：2016-09-12 00:00:00
abstract：:This study aimed to develop and validate a model for the preoperative prediction of the effectiveness of hysteroscopic resection of a uterine cesarean niche in patients with postmenstrual spotting. The predictive model was developed in a primary prospective cohort consisting of 208 patients with niche treated by hyste...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-74622-8
更新日期：2020-10-15 00:00:00
abstract：:The current standard of care for head and neck cancer includes surgical resection of the tumor followed by targeted head and neck radiation. This radiotherapy results in a multitude of negative side effects in adjacent normal tissues. Autophagy is a cellular mechanism that could be targeted to ameliorate these side ef...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep05206
更新日期：2014-06-06 00:00:00
abstract：:Recent work reveals that the extinction of conditioned fear depends upon the interval between conditioning and extinction. Extinction training that takes place within minutes to hours after fear conditioning fails to produce a long-term extinction memory, a phenomenon known as the immediate extinction deficit (IED). N...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-46010-4
更新日期：2019-07-01 00:00:00
abstract：:Propagation of oscillatory spike firing activity at specific frequencies plays an important role in distributed cortical networks. However, there is limited evidence for how such frequency-specific signals are induced or how the signal spectra of the propagating signals are modulated during across-layer (radial) and i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-26054-8
更新日期：2018-05-16 00:00:00
abstract：:Interleukin-27 (IL-27) is an important cytokine in inflammatory diseases, including coronary artery disease (CAD). To explore the precise role of IL-27 in CAD, we investigated the genetic association between IL27 and CAD in the GeneID Chinese Han population. A two-stage case control association analysis was performed ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep25782
更新日期：2016-05-12 00:00:00
abstract：:Invasive motor Cortex Stimulation (iMCS) was introduced in the 1990's for the treatment of chronic neuropathic orofacial pain (CNOP), although its effectiveness remains doubtful. However, CNOP is known to be a heterogeneous group of orofacial pain disorders, which can lead to different responses to iMCS. Therefore, th...
journal_title：Scientific reports
pub_type： 杂志文章,meta分析
doi：10.1038/s41598-020-64177-z
更新日期：2020-04-28 00:00:00
abstract：:Breast cancer brain metastasis (BCBM) remains a major clinical problem. Approximately 10-16% of patients with breast cancer develop brain metastases (BCBM). However, no systemic therapy has gained regulatory approval for the specific treatment of BCBM and this remains an area of persistent, unmet medical need. Rapid, ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-36874-3
更新日期：2019-01-24 00:00:00
abstract：:The unfolded protein response (UPR) not only resolves endoplasmic reticulum (ER) stress, but also regulates cellular physiological functions. In this study, we first linked the UPR to the physiological roles of brown adipose tissue (BAT). BAT is one of the tissues that control energy homeostasis in the body. Brown adi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep16580
更新日期：2015-11-16 00:00:00
abstract：:Bears are iconic mammals with a complex evolutionary history. Natural bear hybrids and studies of few nuclear genes indicate that gene flow among bears may be more common than expected and not limited to polar and brown bears. Here we present a genome analysis of the bear family with representatives of all living spec...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep46487
更新日期：2017-04-19 00:00:00
