Whole genome and transcriptome sequencing of matched primary and peritoneal metastatic gastric carcinoma.

abstract：:Metabolic syndrome (MS) could be associated with liver function. Our study aimed to investigate the association between liver function and MS in a large cohort of Chinese men and women. We enrolled 32,768 ostensibly healthy participants. The associations between liver function and MS of both genders were analyzed sepa...

journal_title：Scientific reports

authors： Wang S,Zhang J,Zhu L,Song L,Meng Z,Jia Q,Li X,Liu N,Hu T,Zhou P,Zhang Q,Liu L,Song K,Jia Q

更新日期：2017-03-20 00:00:00

abstract：:Knowledge of the direct role humans have had in changing the landscape requires the perspective of historical and archaeological sources, as well as climatic and ecologic processes, when interpreting paleoecological records. People directly impact land at the local scale and land use decisions are strongly influenced ...

journal_title：Scientific reports

authors： Mensing SA,Schoolman EM,Tunno I,Noble PJ,Sagnotti L,Florindo F,Piovesan G

更新日期：2018-02-01 00:00:00

abstract：:Although it is known that malaria parasites proliferate in the midgut of mosquito vector, their detailed behaviors, from gamete maturation to formation of next generation sporozoite, have not been fully understood at cellular or molecular level. This is mainly attributed to technical difficulties of dissection and who...

journal_title：Scientific reports

authors： Mori T,Hirai M,Mita T

更新日期：2019-02-11 00:00:00

abstract：:Metastatic colorectal cancer is the fourth most common cause of cancer death. Current options in palliation such as hyperthermic intraperitoneal chemotherapy (HIPEC) present severe side effects. Recent research efforts suggested the therapeutic use of oxidant-enriched liquid using cold physical plasma. To investigate ...

journal_title：Scientific reports

authors： Freund E,Liedtke KR,van der Linde J,Metelmann HR,Heidecke CD,Partecke LI,Bekeschus S

更新日期：2019-01-24 00:00:00

abstract：:Split bull's eye (SBE) antennas exhibit much larger extraordinary optical transmission and strong polarization dependence rather than bull's eye (BE) antennas in the infrared range due to the introduced sub-wavelength slit. Here, we demonstrate a dual-split bull's eye (DSBE) antenna, which consists of two sub-waveleng...

journal_title：Scientific reports

authors： Yang M,Ren FF,Pu L,Xiao L,Sheng Y,Wang J,Lu H,Zheng Y,Shi Y

更新日期：2016-12-19 00:00:00

abstract：:Zika virus (ZIKV) is a recently re-emerged flavivirus transmitted to humans by mosquito bites but also from mother to fetus and by sexual intercourse. We here show that primary human endometrial stromal cells (HESC) are highly permissive to ZIKV infection and support its in vitro replication. ZIKV envelope expression ...

journal_title：Scientific reports

authors： Pagani I,Ghezzi S,Ulisse A,Rubio A,Turrini F,Garavaglia E,Candiani M,Castilletti C,Ippolito G,Poli G,Broccoli V,Panina-Bordignon P,Vicenzi E

更新日期：2017-03-10 00:00:00

abstract：:Paedomorphosis and metamorphosis are two major developmental processes that characterize the evolution of complex life cycles in many lineages. Whereas these processes were fixed in some taxa, they remained facultative in others, with alternative phenotypes expressed in the same populations. From a genetic perspective...

journal_title：Scientific reports

authors： Oromi N,Michaux J,Denoël M

更新日期：2016-08-18 00:00:00

abstract：:We design an optical scheme to generate hyperentanglement correlated with degrees of freedom (DOFs) via quantum dots (QDs), weak cross-Kerr nonlinearities (XKNLs), and linearly optical apparatuses (including time-bin encoders). For generating hyperentanglement having its own correlations for two DOFs (polarization and...

journal_title：Scientific reports

authors： Hong CH,Heo J,Kang MS,Jang J,Yang HJ

更新日期：2018-02-07 00:00:00

abstract：:The ability of metasurfaces to manipulate light at the subwavelength scale offers unprecedented functionalities for passive and active lasing devices. However, applications of metasurfaces to optical devices are rare due to fabrication difficulties. Here, we present quantum dot light emitting diodes (QDLEDs) with a me...

journal_title：Scientific reports

authors： Park Y,Kim J,Cho KS,Kim H,Lee MK,Lee JS,Kim UJ,Hwang SW,Brongersma ML,Roh YG,Park QH

更新日期：2017-11-07 00:00:00

abstract：:Crohn's disease (CD) has been associated with an increased consumption of n-6 polyunsaturated fatty acid (PUFA), while greater intake of n-3 PUFA has been associated with a reduced risk. We sought to investigate serum fatty acid composition in CD, and associations of fatty acids with disease activity, cytokines, and a...

journal_title：Scientific reports

authors： Scoville EA,Allaman MM,Adams DW,Motley AK,Peyton SC,Ferguson SL,Horst SN,Williams CS,Beaulieu DB,Schwartz DA,Wilson KT,Coburn LA

更新日期：2019-02-27 00:00:00

abstract：:In order to screen out an effective bone loss protectant from natural plant polyphenol and to elucidate the mechanism of the plant polyphenols that alleviate bone loss under simulated microgravity, the proliferation activities of 9 total polyphenol extracts from natural product (TPENP) on osteoblasts were measured. Po...

journal_title：Scientific reports

authors： Diao Y,Chen B,Wei L,Wang Z

更新日期：2018-08-24 00:00:00

abstract：:Phosphoinositides play important roles in numerous intracellular membrane pathways. Little is known about the regulation or function of these lipids in rod photoreceptor cells, which have highly active membrane dynamics. Using new assays with femtomole sensitivity, we determined that whereas levels of phosphatidylinos...

journal_title：Scientific reports

authors： He F,Agosto MA,Anastassov IA,Tse DY,Wu SM,Wensel TG

更新日期：2016-06-01 00:00:00

abstract：:Balance is a very important function that allows maintaining a stable stance needed for many daily life activities and for preventing falls. We investigated whether balance control could be improved by a placebo procedure consisting of verbal suggestion. Thirty healthy volunteers were randomized in two groups (placebo...

journal_title：Scientific reports

authors： Villa-Sánchez B,Emadi Andani M,Menegaldo G,Tinazzi M,Fiorio M

更新日期：2019-04-23 00:00:00

abstract：:In the fifty years since the postulation of Moore's Law, the increasing energy consumption in silicon electronics has motivated research into emerging devices. An attractive research direction is processing information via the phase of spin waves within magnonic-logic circuits, which function without charge transport ...

journal_title：Scientific reports

authors： Kanazawa N,Goto T,Sekiguchi K,Granovsky AB,Ross CA,Takagi H,Nakamura Y,Uchida H,Inoue M

更新日期：2017-08-11 00:00:00

abstract：:This work explores simulations of polarized discussions from a general and theoretical premise. Specifically the question of whether a plausible avenue exists for a subgroup in an online social network to find a disagreement beneficial and what that benefit could be. A methodological framework is proposed which repres...

journal_title：Scientific reports

authors： Garibay I,Mantzaris AV,Rajabi A,Taylor CE

更新日期：2019-12-09 00:00:00

abstract：:By employing a single AlGaN layer with low Al composition, high quality and uniformity AlGaN/GaN heterostructures have been successfully grown on Si substrates by metal-organic chemical vapor deposition (MOCVD). The heterostructures exhibit a high electron mobility of 2150 cm(2)/Vs with an electron density of 9.3 × 10...

journal_title：Scientific reports

authors： Cheng J,Yang X,Sang L,Guo L,Zhang J,Wang J,He C,Zhang L,Wang M,Xu F,Tang N,Qin Z,Wang X,Shen B

更新日期：2016-03-10 00:00:00

abstract：:Moonlighting proteins, including metabolic enzymes acting as transcription factors (TF), are present in a variety of organisms but have not been described in higher fungi so far. In a previous genome-wide analysis of the TF repertoire of the plant-symbiotic fungus Tuber melanosporum, we identified various enzymes, inc...

journal_title：Scientific reports

authors： Levati E,Sartini S,Bolchi A,Ottonello S,Montanini B

更新日期：2016-04-28 00:00:00

abstract：:Understanding source-sink dynamics is important for conservation management, particularly when climatic events alter species' distributions. Following a 2011 'marine heatwave' in Western Australia, we observed high recruitment of the endemic fisheries target species Choerodon rubescens, towards the cooler (southern) e...

journal_title：Scientific reports

authors： Cure K,Thomas L,Hobbs JA,Fairclough DV,Kennington WJ

更新日期：2017-08-17 00:00:00

abstract：:Speaking involves coordination of multiple neuromotor systems, including respiration, phonation and articulation. Developing non-invasive imaging methods to study how the brain controls these systems is critical for understanding the neurobiology of speech production. Recent models and animal research suggest that reg...

journal_title：Scientific reports

authors： Correia JM,Caballero-Gaudes C,Guediche S,Carreiras M

更新日期：2020-03-11 00:00:00

abstract：:We report a novel and facile method to synthesize sulfur-doped titanium oxide sheets and realize TiS2-TiO2 heterostructures by means of a sequential sulfurization and oxidation step in a dual-zone chemical vapor deposition furnace. The inclusion of chlorine and argon gases during the growth of such titanium-based comp...

journal_title：Scientific reports

authors： Etghani SA,Ansari E,Mohajerzadeh S

更新日期：2019-11-29 00:00:00

abstract：:Urothelial carcinoma (UC) is a common disease causing significant morbidity and mortality as well as considerable costs for health systems. Extensive aberrant methylation of DNA is broadly documented in early UC, contributing to genetic instability, altered gene expression and tumor progression. However the triggers i...

journal_title：Scientific reports

authors： Erichsen L,Seifert HH,Schulz WA,Hoffmann MJ,Niegisch G,Araúzo-Bravo MJ,Bendhack ML,Poyet C,Hermanns T,Beermann A,Hassan M,Theis L,Mahmood W,Santourlidis S

更新日期：2020-03-02 00:00:00

abstract：:High-k dielectric oxides are supposedly ideal gate-materials for ultra-high doping in graphene and other 2D-crystals. Here, we report a temperature-dependent electronic transport study on chemical vapor deposited-graphene gated with SrTiO₃ (STO) thin film substrate. At carrier densities away from charge neutrality poi...

journal_title：Scientific reports

authors： Saha S,Kahya O,Jaiswal M,Srivastava A,Annadi A,Balakrishnan J,Pachoud A,Toh CT,Hong BH,Ahn JH,Venkatesan T,Özyilmaz B

更新日期：2014-08-22 00:00:00

abstract：:The analysis of questionnaires often involves representing the high-dimensional responses in a low-dimensional space (e.g., PCA, MCA, or t-SNE). However questionnaire data often contains categorical variables and common statistical model assumptions rarely hold. Here we present a non-parametric approach based on Fishe...

journal_title：Scientific reports

authors： Har-Shemesh O,Quax R,Lansing JS,Sloot PMA

更新日期：2020-05-25 00:00:00

abstract：:The Zika virus (ZIKV) outbreak in the Americas and South Pacific poses a significant burden on human health because of ZIKV's neurotropic effects in the course of fetal development. Vaccine candidates against ZIKV are coming online, but immunological tools to study anti-ZIKV responses in preclinical models, particular...

journal_title：Scientific reports

authors： Chahal JS,Fang T,Woodham AW,Khan OF,Ling J,Anderson DG,Ploegh HL

更新日期：2017-03-21 00:00:00

abstract：:We quantitatively evaluated breast tumor movement and volume changes between magnetic resonance imaging (MRI) scans in prone and supine positions. Twenty-seven breast tumor patients who received neoadjuvant systemic therapy (NST) for breast-conserving surgery were studied. Before and after NST, MRI scans in prone and ...

journal_title：Scientific reports

authors： Wang CB,Lee S,Kim T,Hong D,Kim GB,Yoon GY,Kim HH,Kim N,Ko B

更新日期：2020-03-17 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Aponte-Santamaría C,Fischer G,Båth P,Neutze R,de Groot BL

更新日期：2017-12-05 00:00:00

abstract：:3,4-Methylenedioxymethamphetamine (MDMA), a common recreational drug, is known to cause serotonergic neurotoxicity in the brain. Dextromethorphan (DM) is a widely used antitussive reported to exert anti-inflammatory effect in vivo. In this study, we examined the long-term effect of MDMA on the primate serotonergic sys...

journal_title：Scientific reports

authors： Ma KH,Liu TT,Weng SJ,Chen CF,Huang YS,Chueh SH,Liao MH,Chang KW,Sung CC,Hsu TH,Huang WS,Cheng CY

更新日期：2016-12-12 00:00:00

abstract：:It is a significant challenge to regenerate full-thickness skin defects with sweat glands. Various skin substitutes have been developed to resolve this issue with minimal success. In this study, to yield a novel construct for in situ regeneration of sweat glands, the collagen-chitosan porous scaffold was combined with...

journal_title：Scientific reports

authors： Kolakshyapati P,Li X,Chen C,Zhang M,Tan W,Ma L,Gao C

更新日期：2017-12-15 00:00:00

abstract：:The objective of the study was to estimate if altered levels of alpha-synuclein can be detected in tear fluid of patients with Parkinson's disease (PD). Therefore, tear fluid samples of 75 PD patients, 75 control subjects and 31 atypical Parkinsonian patients were collected and analyzed in triplicates using an ultra-s...

journal_title：Scientific reports

authors： Maass F,Rikker S,Dambeck V,Warth C,Tatenhorst L,Csoti I,Schmitz M,Zerr I,Leha A,Bähr M,Lingor P

更新日期：2020-05-22 00:00:00

abstract：:Dogs (Canis familiaris) are the first animals to be domesticated by humans and the only ones domesticated by mobile hunter-gatherers. Wolves and humans were both persistent, pack hunters of large prey. They were species competing over resources in partially overlapping ecological niches and capable of killing each oth...

journal_title：Scientific reports

authors： Lahtinen M,Clinnick D,Mannermaa K,Salonen JS,Viranta S

更新日期：2021-01-07 00:00:00