Changing trends in diagnosis, staging, treatment and survival in lung cancer: comparison of three consecutive cohorts in an Australian lung cancer centre.

abstract：:It is generally accepted that the prevalence of food allergy has been increasing in recent decades, particularly in westernised countries, yet high-quality evidence that is based on challenge confirmed diagnosis of food allergy to support this assumption is lacking because of the high cost and potential risks associat...

journal_title：Internal medicine journal

authors： Tang ML,Mullins RJ

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) is a common cause of incidental liver test abnormalities. General practitioners (GP) have a key role in identifying people with NAFLD at risk of significant liver disease. Recent specialist guidelines emphasise the use of fibrosis algorithms or serum biomarkers rathe...

journal_title：Internal medicine journal

authors： Patel PJ,Banh X,Horsfall LU,Hayward KL,Hossain F,Johnson T,Stuart KA,Brown NN,Saad N,Clouston A,Irvine KM,Russell AW,Valery PC,Williams S,Powell EE

更新日期：2018-02-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) has been described as a cause of thrombotic microangiopathy, especially thrombotic thrombocytopenic purpura (TTP). Haemolytic-uraemic syndrome (HUS) is less frequent in SLE. We report a case of such an association during an episode of severe lupus nephritis in a young woman, who was ...

journal_title：Internal medicine journal

authors： Samson M,Audia S,Leguy V,Berthier S,Janikashvili N,Martin L,Bonnotte B,Lorcerie B

更新日期：2012-01-01 00:00:00

abstract：:Over the last 20 years, clinical medicine has witnessed rapid expansion in its underlying evidence base, greater demand for accountability in clinicians' use of limited resources and increasing societal expectation for health care that confers proven benefit at reasonable cost to all eligible recipients. Health servic...

journal_title：Internal medicine journal

authors： Scott I,Campbell D

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Medical school and resident training programmes offer different learning opportunities and outcomes. The aim of the study was to assess medical student and intern experience in common clinical procedures. METHODS:Interns employed in a metropolitan teaching hospital from 2000 to 2004 completed a survey of ex...

journal_title：Internal medicine journal

authors： Boots RJ,Egerton W,McKeering H,Winter H

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Long-term prognosis of acute coronary syndromes (ACS) in human immunodeficiency virus (HIV)-infected patients is unknown. AIMS:To compare outcomes after ACS in HIV-infected and uninfected patients. METHODS:Retrospective observational study. HIV cases were matched with two HIV-uninfected controls for age, s...

journal_title：Internal medicine journal

authors： Postigo A,Díez-Delhoyo F,Devesa C,Bruña V,Clavero-Olmos M,Vicent L,Juárez M,Sousa I,Fernández-Avilés F,Martínez-Sellés M

更新日期：2020-12-01 00:00:00

abstract：:The vulnerability of older people to serious underlying medical illness and adverse effects of psychotropics means that the safe and effective treatment of severe agitation can be lifesaving, the primary management goals being to create a safe environment for the patient and others, and to facilitate assessment and tr...

journal_title：Internal medicine journal

authors： Peisah C,Chan DK,McKay R,Kurrle SE,Reutens SG

更新日期：2011-09-01 00:00:00

abstract：:Large volume paracentesis is effective in relieving the symptoms of malignant ascites, but frequent procedures are often required. Permanent peritoneal ports are an alternative to repeated procedures. We describe our experience with the use of peritoneal ports in patients at Middlemore Hospital (Auckland, New Zealand)...

journal_title：Internal medicine journal

authors： Chen BS,Wong SHC,Hawkins S,Huggins L

更新日期：2018-12-01 00:00:00

abstract：:Vancomycin remains a clinically useful antibiotic despite the advent of several alternative drugs. Optimising vancomycin therapy with therapeutic drug monitoring is widely recommended. The aim of therapeutic drug monitoring is to help the clinician to achieve target pharmacodynamic parameters in the case of vancomycin...

journal_title：Internal medicine journal

authors： Avent ML,Vaska VL,Rogers BA,Cheng AC,van Hal SJ,Holmes NE,Howden BP,Paterson DL

更新日期：2013-02-01 00:00:00

abstract：:Mechanical ventilation as a resource is limited and may lead to poor outcomes in at-risk populations. Critical care supports may not be preferred by those at risk of deterioration in the COVID-19 setting. Patient-centred communication and shared decision-making should continue to remain central to clinical practice. ...

journal_title：Internal medicine journal

authors： Simpson N,Milnes S,Steinfort D

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Unrelated umbilical cord blood has emerged as an alternative stem cell source for allogeneic transplantation for patients with haematological malignancies, but in adults is limited by the low number of stem cells present in banked cord blood units. We report our experience with double cord blood transplants ...

journal_title：Internal medicine journal

authors： Bradstock K,Hertzberg M,Kerridge I,Svennilson J,George B,McGurgan M,Huang G,Antonenas V,Gottlieb D

更新日期：2009-11-01 00:00:00

abstract：:Legionella species are a common cause of community-acquired pneumonia, infrequently complicated by cavitary disease. We describe Legionella pneumophila pneumonia and abscess formation in an immunosuppressed patient receiving corticosteroid therapy for metastatic breast carcinoma. The predisposing role of corticosteroi...

journal_title：Internal medicine journal

authors： Guy SD,Worth LJ,Thursky KA,Francis PA,Slavin MA

更新日期：2011-10-01 00:00:00

abstract：:Almost everywhere in the body there are phospholipids, not only comprising the lipid bilayer of membranes, but also in the free state. What is seldom appreciated, except in respirology, is that these 'free' phospholipids are unusual in that many are highly surface active. Surface activity is a property of certain subs...

journal_title：Internal medicine journal

authors： Hills BA

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:The altered status of iron metabolism is reported in hereditary haemochromatosis and in non-alcoholic liver fatty disease. We investigated the relation between the H63D HFE mutation gene and non-alcoholic steatohepatitis (NASH). METHODS:We studied as outpatients, 272 Italian persons with NASH and compared t...

journal_title：Internal medicine journal

authors： Neri S,Pulvirenti D,Signorelli S,Ignaccolo L,Tsami A,Mauceri B,Misseri M,Interlandi D,Cutuli N,Castellino P

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:The clinical significance of extreme hyperferritinaemia has come under scrutiny with the increasing recognition of haemophagocytic lymphohistiocytosis (HLH) in adults. Most studies of hyperferritinaemia have focused on serum ferritin greater than 1000 μg/L, often in ambulatory patients. The conditions associ...

journal_title：Internal medicine journal

authors： Wormsbecker AJ,Sweet DD,Mann SL,Wang SY,Pudek MR,Chen LY

更新日期：2015-08-01 00:00:00

abstract：:The annual Leonard Ball Orations illustrate changing perspectives in Australia over 30 years on medical and social effects of misuse of alcohol and other substances. The first oration, in 1968, examined causal factors in the context of 'agent', 'purveyor' and 'host' and provided themes for subsequent orators. In regar...

journal_title：Internal medicine journal

authors： Mackay IR

更新日期：2001-08-01 00:00:00

abstract：AIMS:To measure factors associated with underuse of beta-blocker therapy after myocardial infarction (MI). METHODS:The Newcastle and Perth collaborating centres of the World Health Organization (WHO) MONICA project (to MONItor trends and determinants of Cardiovascular disease) systematically evaluated all patients adm...

journal_title：Internal medicine journal

authors： Nicholls SJ,McElduff P,Dobson AJ,Jamrozik KD,Hobbs MS,Leitch JW

更新日期：2001-09-01 00:00:00

abstract：:Individualised drug dosing has been shown to improve patient outcomes and reduce adverse drug events. One method of individualised medicine is the Bayesian approach, which uses prior information about how the population responds to therapy, to inform clinicians about how a specific individual is responding to their cu...

journal_title：Internal medicine journal

authors： Donagher J,Martin JH,Barras MA

更新日期：2017-05-01 00:00:00

abstract：AIM:To determine diagnostic rate, complications and patient tolerability of endobronchial ultrasound-guide sheath (EBUS-GS) and computed tomography (CT)-guided percutaneous core biopsy for peripheral lung lesions. METHODS:Lesions >1 cm diameter on CT were randomised to either EBUS-GS or CT-guided biopsy. Excluded were...

journal_title：Internal medicine journal

authors： Fielding DI,Chia C,Nguyen P,Bashirzadeh F,Hundloe J,Brown IG,Steinke K

更新日期：2012-08-01 00:00:00

abstract：:Perhexiline is a prophylactic anti-anginal agent that ameliorates the metabolic basis for myocardial ischaemia and is increasingly used in the management of acute coronary syndromes. No intravenous preparation is available and usual oral loading regimens require 2-3 days to achieve therapeutic drug levels. Two patient...

journal_title：Internal medicine journal

authors： Philpott A,Chandy S,Morris R,Horowitz JD

更新日期：2004-06-01 00:00:00

abstract：:Interaction between doctors and the pharmaceutical industry is long-standing and ingrained in modern practice. Doctors-in-training are at a vulnerable stage of their careers, both in requiring knowledge and forming lasting relationships. There is evidence that limiting contact between industry and junior doctors has a...

journal_title：Internal medicine journal

authors： Pokorny AM,Gittins CB

更新日期：2015-10-01 00:00:00

abstract：:There is accumulating evidence that point-of-care delivery of clinical information such as evidence-based medicine, practice guidelines and drug information can streamline clinical practice and reduce preventable errors. In Australia, hospital-based physicians have -generally been slow to fully use these resources to ...

journal_title：Internal medicine journal

authors： Wilcox RA,Whitham EM

更新日期：2003-11-01 00:00:00

abstract：:Depression, ischaemic heart disease and cerebrovascular disease are important causes of morbidity and are among the leading contributors to global health burden. These conditions often occur in the same patient, resulting in considerably greater effect on health than combinations of chronic diseases without depression...

journal_title：Internal medicine journal

authors： Ziegelstein RC,Parakh K,Sakhuja A,Bhat U

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The 2001 National Health and Medical Research Council/Australasian Society of Blood Transfusion Clinical Practice Guidelines for cryoprecipitate are being updated, and cryoprecipitate has been incorporated into new Patient Blood Management modules. AIMS:This clinical audit sought to clarify current cryoprec...

journal_title：Internal medicine journal

authors： Anderson MA,Glazebrook B,Cutts B,Stevenson L,Bielby L,Borosak M

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Surveillance for colorectal neoplasia in inflammatory bowel disease (IBD) is widely practised despite a lack of convincing mortality reduction. The psychological impact of this approach is largely unexplored. AIM:To examine psychological well-being among IBD subjects undergoing colonoscopic surveillance for...

journal_title：Internal medicine journal

authors： Mountifield R,Bampton P,Prosser R,Mikocka-Walus A,Andrews JM

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Timor-Leste is one of the poorest countries in the world. The East Timor Hearts Fund is a charitable organisation involving Australian cardiologists providing outreach screening and access to cardiac interventions. AIMS:To assess ten years of clinical volume, demographics and patient outcomes. Our intention...

journal_title：Internal medicine journal

authors： Paratz ED,Mock N,Gutman SJ,Horton A,Creati L,Appelbe A,Eggleton S,Kushwaha V,da Silva Almeida IT,Monteiro A,Bayley N

更新日期：2020-07-01 00:00:00

abstract：:It has been stated that academic medicine is in a worldwide crisis. Is this decline in hospital academic practice a predictable consequence of modern clinical practice with its emphasis on community and outpatient-based services as well as a corporate health-care ethos or does it relate to innate problems in the train...

journal_title：Internal medicine journal

authors： Wilson A

更新日期：2007-11-01 00:00:00

abstract：:Chronic lead exposure is recognized as a potential cause of hyperuricaemia, kidney damage and hypertension. The fascinating story of lead poisoning and nephrotoxicity illustrates the utility of descriptive studies in the early elucidation of a new disease entity. The pursuit towards understanding lead nephropathy is p...

journal_title：Internal medicine journal

authors： Chow KM,Liu ZC,Szeto CC

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Management of acute ischaemic stroke is time critical. Reducing time to treatment with thrombolysis is strongly associated with improved outcomes in properly selected patients. However, there are barriers to ensuring timely treatment in the hospital setting. AIM:To determine if simple, no-cost protocol chan...

journal_title：Internal medicine journal

authors： Silsby M,Duma SR,Fois AF,Yin YWK,Koryzna J,Mahant N,Evans A,Fung VSC

更新日期：2019-11-01 00:00:00

abstract：:As the mortality rate from breast cancer decreases, the issues facing breast cancer survivors are becoming increasingly important. Survivors of all ages may face physical and psychosocial consequences of their diagnosis and treatments. However, the long-term fertility and menopause-related side-effects of adjuvant the...

journal_title：Internal medicine journal

authors： Friedlander M,Thewes B

更新日期：2003-08-01 00:00:00