Single versus double unrelated umbilical cord blood units for allogeneic transplantation in adults with advanced haematological malignancies: a retrospective comparison of outcomes.

abstract：BACKGROUND:The short Synacthen test is widely used to assess the hypothalamus pituitary adrenal axis in the outpatient setting. In the inpatient setting however, technical difficulties to adhere to the protocol may pose a challenge for using this test. AIMS:In this study we attempted to find the most suitable basal se...

journal_title：Internal medicine journal

authors： Tolkin L,Vidberg M,Munter G

更新日期：2020-08-24 00:00:00

abstract：:We hereby present two case reports of moderate coronavirus disease patients, suffering from profound hypoxaemia, further deteriorating later on. A schedule pre-planned awake prone position manoeuvres were executed during their hospital stay. Following this, the patients' saturation improved, later to be weaned from ox...

journal_title：Internal medicine journal

authors： Cohen D,Wasserstrum Y,Segev A,Avaky C,Negru L,Turpashvili N,Anani S,Zilber E,Lasman N,Athamna A,Segal O,Shenhav-Saltzman G,Segal G

更新日期：2020-08-01 00:00:00

abstract：:Minimisation of radiation exposure with cardiac imaging reduces the potential of secondary side effects. Radiation exposure from myocardial perfusion scintigraphy and computed tomography coronary angiography (CTCA) was compared. Overall doses were low with both modalities. Doses were lower in the CTCA group, but by on...

journal_title：Internal medicine journal

authors： Tsay IM,Subiakto I,Asrar Ul Haq M,Castles AV,Allman K,Hayat U,Rudd N,Barlis P,van Gaal W

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Neoadjuvant chemoradiation therapy (CRT) is standard of care treatment for locally advanced rectal cancer (LARC). A pathologic complete response (pCR) following CRT is an early indicator of treatment benefit and associated with excellent survival outcomes. As capecitabine replaces infusional 5-fluorouracil (...

journal_title：Internal medicine journal

authors： Loft M,Wong HL,Kosmider S,Lee M,Tie J,Wong R,Jones IT,Croxford M,Steel M,Faragher I,Guerrieri M,Christie M,Gibbs P

更新日期：2020-09-08 00:00:00

abstract：BACKGROUND:There are no sufficient data available on the use of febuxostat in patients undergoing dialysis. AIM:We investigated the efficacy and tolerability of febuxostat in gout patients on dialysis. METHODS:We retrospectively reviewed clinical and laboratory data available from a referral center from January 2012 ...

journal_title：Internal medicine journal

authors： Choi SY,Choi SW,Lee S,So MW,Oh JS,Lim DH

更新日期：2020-02-11 00:00:00

abstract：BACKGROUND:Population-based studies of the prevalence of all functional gastrointestinal disorders (FGID) using the Rome II criteria are lacking. It is also not certain whether subjects who meet the Rome II criteria for an FGID are different in terms of demographic and psychological characteristics from those subjects ...

journal_title：Internal medicine journal

authors： Boyce PM,Talley NJ,Burke C,Koloski NA

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Informed consent is a mainstay of clinical practice, with both moral and legal forces. Material disclosure about extreme treatments, however, is unlikely to convey the full impact of the experience of treatment. Informed consent may be flawed under such circumstances. The aims of this study were to compare e...

journal_title：Internal medicine journal

authors： Little M,Jordens CF,McGrath C,Montgomery K,Lipworth W,Kerridge I

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:The ACT Genetic Service at The Canberra Hospital evaluates the genetic risk of individuals for inherited diseases, and provides counselling and genetic testing where appropriate. AIM:To evaluate the current referral practice for patients with a personal and/or family history of breast and/or ovarian cancer,...

journal_title：Internal medicine journal

authors： Aitken L,Warwick L,Davis A

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Hypercholesterolaemia is a pivotal risk factor for cardiovascular and cerebrovascular disease and is treated with many effective lipid-lowering agents. Statins are often used alone or in combination with ezetimibe. Combination therapy is more effective because of its complementary approach, which has major b...

journal_title：Internal medicine journal

authors： Luo L,Yuan X,Huang W,Ren F,Zhu H,Zheng Y,Tang L

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:The relationship between serum triglycerides (TG) level and the risk of coronary heart disease (CHD) mortality remains controversial. AIMS:To evaluate whether TG level is a risk factor for CHD in elderly people from general population, and to look for interactions between TG and other risk factors. METHODS...

journal_title：Internal medicine journal

authors： Mazza A,Tikhonoff V,Schiavon L,Casiglia E

更新日期：2005-10-01 00:00:00

abstract：:Association between tumour necrosis alpha inhibitors and weight gain has been reported. We examined weight change in our cohort of inflammatory bowel disease patients treated with infliximab (IFX) for over 12 months, its associations and financial implications. Two-thirds of patients gained weight during the course of...

journal_title：Internal medicine journal

authors： Kaazan P,Tan Z,Bednarz J,Hughes J,Grafton R,Andrews JM

更新日期：2020-09-01 00:00:00

abstract：:Carbimazole is a drug that is widely used for hyperthyroid disorders, such as Graves' disease. Agranulocytosis is a rare idiosyncratic adverse reaction to the drug which is potentially fatal. This report describes a patient with a history of successfully treated pyoderma gangrenosum, who developed agranulocytosis 3 we...

journal_title：Internal medicine journal

authors： Yip G,Ekinci E,Lee ST,Jerums G,Grossmann M

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Neutropenic fever is a frequently encountered complication when caring for cancer patients and can lead to intensive care admission, with high mortality rates in those patients who require invasive mechanical ventilation (IMV). Although hospital survival in this population has improved, long-term outcomes of...

journal_title：Internal medicine journal

authors： Mackintosh D,Way M,Reade MC,Dhanani J

更新日期：2020-05-01 00:00:00

abstract：:Decompressive hemicraniectomy (DHC) has been shown to reduce mortality in malignant middle cerebral artery (MCA) infarction. Our primary objective was to compare 1-year mortality between patients receiving DHC for malignant MCA infarction at our institution based on hospital of origin. We retrospectively reviewed the ...

journal_title：Internal medicine journal

authors： Smyth D,Weatherall M,Rosemergy I,Woon K,Lanford J

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:A number of haematological malignancies can be cured by allogeneic stem cell transplantation but only approximately 30% of Australians have a suitable histocompatible related donor. Matched donors can be found on international registries of unrelated volunteers for a proportion of the remaining patients. For...

journal_title：Internal medicine journal

authors： Bradstock KF,Hertzberg MS,Kerridge IH,Svennilson J,McGurgan M,Huang G,Antonenas V,Gottlieb DJ

更新日期：2006-06-01 00:00:00

abstract：:This paper examines the differences between clinical and public health ethics and provides several examples of contemporary public health challenges that pose ethical questions. The relations among ethics, rights and obligations are explored, because public health philosophers propose these as different ways for publi...

journal_title：Internal medicine journal

authors： Leeder SR

更新日期：2004-07-01 00:00:00

abstract：AIM:To evaluate New Zealand media articles on their coverage of key issues regarding health interventions and whether it is consistent with available evidence. METHODS:A retrospective analysis was carried out of all articles published in five New Zealand media sources over a 6-week period between 15 October and 26 Nov...

journal_title：Internal medicine journal

authors： Robinson C,Cutfield N,Mottershead J,Sharples K,Richards R,Kingan J,Ledgard C,Liyanage A,McLean J,Nahab F,Stewart F,Strachan S,Tucker K,Zhang Z

更新日期：2018-08-01 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) is a prevalent, chronic and heterogeneous endocrine condition, with reproductive, metabolic and psychological features. Insulin resistance and hyperandrogenaemia are the key pathophysiological hormonal abnormalities. Insulin resistance is a significant contributor to the reproductive a...

journal_title：Internal medicine journal

authors： Shorakae S,Boyle J,Teede H

更新日期：2014-08-01 00:00:00

abstract：:Lymphangioleiomyomatosis (LAM) is a rare disease affecting women, classically involving the lungs. However, extrapulmonary manifestations also occur, including renal angiomyolipomas, retroperitoneal lymphangioleiomyomas and extrathoracic lymphadenopathy. The lung disease is hormone-responsive, but no information exist...

journal_title：Internal medicine journal

authors： Sandrini A,Silverstone E,Yates DH

更新日期：2011-12-01 00:00:00

abstract：:Autoimmune inflammatory rheumatic diseases (AIIRD), such as rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis are often complicated by infection, which results in significant morbidity and mortality. The increased risk of infection is probably due to a combination of immunosuppressive effects of the...

journal_title：Internal medicine journal

authors： Wong PKK,Bagga H,Barrett C,Hanrahan P,Johnson D,Katrib A,Leder K,Marabani M,Pentony P,Riordan J,White R,Young L

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Plasma homocysteine is elevated in patients with end-stage renal disease (ESRD) and is a risk factor for cardiovascular disease. Folic acid has been shown to partially reduce homocysteine levels in dialysis patients. It is not known whether vitamin B12 reduces homocysteine independent of folic acid in patien...

journal_title：Internal medicine journal

authors： Polkinghorne KR,Zoungas S,Branley P,Villanueva E,McNeil JJ,Atkins RC,McGrath BP,Kerr PG

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Quick Sepsis-related Organ Failure Assessment (qSOFA) is recommended for use by the most recent international sepsis definition taskforce to identify suspected sepsis in patients outside the Intensive Care Unit (ICU) at risk of adverse outcomes. Evidence of its comparative effectiveness with existing sepsis ...

journal_title：Internal medicine journal

authors： Li L,Rathnayake K,Green M,Shetty A,Fullick M,Walter S,Middleton-Rennie C,Meller M,Braithwaite J,Lander H,Westbrook JI

更新日期：2020-01-06 00:00:00

abstract：BACKGROUND/AIM:Families, especially in Chinese society, play a crucial role in care provision for relatives with schizophrenia, but the burden of caregiving has shown to cause significant distress among caregivers. The aim of the study is to assess the degree of stress and burden among caregivers of relatives with schi...

journal_title：Internal medicine journal

authors： Wan KF,Wong MMC

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Iatrogenic medication errors are a cause of medical morbidity and mortality. They result in significant cost to the Australian healthcare system each year. There is limited Australian evidence describing the iatrogenic errors occurring within the hospital system. AIMS:To examine and describe iatrogenic medi...

journal_title：Internal medicine journal

authors： Bourke EM,Greene S,Macleod D,Robinson J

更新日期：2020-06-15 00:00:00

abstract：BACKGROUND:Early involvement of palliative care and advance care planning improves quality of life outcomes and survival for patients with advanced lung cancer, however there are barriers to implementation. AIMS AND METHODS:A single-centre prospective audit reviewing "Goals of Care" (GOC) form completion and palliativ...

journal_title：Internal medicine journal

authors： Conduit C,Thompson M,Thomas R,Nott L,Wuttke M

更新日期：2020-03-23 00:00:00

abstract：:We report the first published case of aggressive diffuse large B-cell (non-Hodgkin) lymphoma in a 35-year-old pregnant woman who had Crohn disease and was taking long-term thiopurine therapy: the patient developed placental insufficiency, and there was intrauterine fetal death. ...

journal_title：Internal medicine journal

authors： Chen G,Crispin P,Cherian M,Dahlstrom JE,Sethna FF,Kaye G,Pavli P,Subramaniam K

更新日期：2016-01-01 00:00:00

abstract：:Autologous stem cell transplantation (ASCT) has a well-established role in the treatment of haematological malignancies. Stem cells are commonly collected following salvage chemotherapy although there may be advantages in collecting earlier in the disease course. A 'rainy day' harvest (RDH) refers to the collection of...

journal_title：Internal medicine journal

authors： Trotman J,Presgrave P,Kwan Y,Tiley C,Estell J,Watson AM,O'Brien TA,Peters D

更新日期：2008-04-01 00:00:00

abstract：AIMS:We sought to assess a broad array of possible precipitants of acute coronary syndromes (ACS) and evaluate their association with detectable inflammatory activation. METHODS AND RESULTS:Within a case-crossover design, using a standardised questionnaire, interviews among 348 ST-elevation myocardial infarction (44%)...

journal_title：Internal medicine journal

authors： Chew DP,Mattschoss S,Horsfall M,Astley C,Vaile JC,Joseph MX

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Many studies support the role of bilirubin as a cytoprotector in chronic inflammatory diseases, such as stroke and atherosclerosis. AIM:To investigate the relationship between serum total bilirubin levels and functional dependence in older adults. METHODS:Data from the National Health and Nutrition Examina...

journal_title：Internal medicine journal

authors： Kao TW,Chou CH,Wang CC,Chou CC,Hu J,Chen WL

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) is a common cause of incidental liver test abnormalities. General practitioners (GP) have a key role in identifying people with NAFLD at risk of significant liver disease. Recent specialist guidelines emphasise the use of fibrosis algorithms or serum biomarkers rathe...

journal_title：Internal medicine journal

authors： Patel PJ,Banh X,Horsfall LU,Hayward KL,Hossain F,Johnson T,Stuart KA,Brown NN,Saad N,Clouston A,Irvine KM,Russell AW,Valery PC,Williams S,Powell EE

更新日期：2018-02-01 00:00:00