When do we transfuse cryoprecipitate?

abstract：BACKGROUND:Management of acute ischaemic stroke is time critical. Reducing time to treatment with thrombolysis is strongly associated with improved outcomes in properly selected patients. However, there are barriers to ensuring timely treatment in the hospital setting. AIM:To determine if simple, no-cost protocol chan...

journal_title：Internal medicine journal

authors： Silsby M,Duma SR,Fois AF,Yin YWK,Koryzna J,Mahant N,Evans A,Fung VSC

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:The parenteral administration of oestradiol acutely protects against exercise-induced myocardial ischaemia in women, but whether this effect is sex-specific is not known. AIMS:The effects of acutely administered conjugated equine oestrogen on exercise-induced myocardial ischaemia in men with established cor...

journal_title：Internal medicine journal

authors： Davis SR,Bradbury J,Bell R,Johns JA

更新日期：2003-05-01 00:00:00

abstract：:The vulnerability of older people to serious underlying medical illness and adverse effects of psychotropics means that the safe and effective treatment of severe agitation can be lifesaving, the primary management goals being to create a safe environment for the patient and others, and to facilitate assessment and tr...

journal_title：Internal medicine journal

authors： Peisah C,Chan DK,McKay R,Kurrle SE,Reutens SG

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Glomerular M-type phospholipase A2 receptor (PLA2 R) is important for diagnosing idiopathic membranous nephropathy (IMN). The relation between glomerular PLA2 R expression and response to treatment remains to be explored. AIMS:We conducted the study to explore the positive rate and clinical significance of ...

journal_title：Internal medicine journal

authors： Liu H,Luo W,Gong S,Ding X

更新日期：2016-11-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) has been described as a cause of thrombotic microangiopathy, especially thrombotic thrombocytopenic purpura (TTP). Haemolytic-uraemic syndrome (HUS) is less frequent in SLE. We report a case of such an association during an episode of severe lupus nephritis in a young woman, who was ...

journal_title：Internal medicine journal

authors： Samson M,Audia S,Leguy V,Berthier S,Janikashvili N,Martin L,Bonnotte B,Lorcerie B

更新日期：2012-01-01 00:00:00

abstract：:The use of tissue-type plasminogen activator (t-PA) in ischaemic stroke outside of experienced stroke centres remains controversial. The aim of this study was to present the initial experience with t-PA in patients with ischaemic stroke at an institution with no prior experience in i.v. stroke thrombolysis and to comp...

journal_title：Internal medicine journal

authors： Bray JE,Coughlan K,Bladin C

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Asthma is associated with fixed airflow obstruction and an increased risk of death. The aim of this study was to relate asthma mortality and airflow obstruction to severity of asthma in a cohort of patients with chronic asthma studied over a 17-year period. METHODS:In 1980, asthma severity based on symptoms...

journal_title：Internal medicine journal

authors： Panizza JA,James AL,Ryan G,de Klerk N,Finucane KE

更新日期：2006-12-01 00:00:00

abstract：:During a pandemic when hospitals are stretched and patients need isolation, the role of hospital-in-the-home (HITH) providing acute medical care at home has never been more relevant. We aimed to define and address the challenges to acute home care services posed by the COVID-19 pandemic. Planning for service operation...

journal_title：Internal medicine journal

authors： Bryant PA,Rogers BA,Cowan R,Bowen AC,Pollard J,Hospital-in-the-Home Society Australasia.

更新日期：2020-10-01 00:00:00

abstract：:Here we report the case of a 69-year-old Chinese Han woman who presented with liver cirrhosis, diabetes mellitus, skin hyperpigmentation, hyperferritinaemia and high transferrin saturation. Subsequent genetic analyses identified a novel heterozygous mutation (p.Cys326Phe) in the SLC40A1 gene. This is the first report ...

journal_title：Internal medicine journal

authors： Chen SR,Yang LQ,Chong YT,Jie YS,Wu YK,Yang J,Lin GL,Li XH

更新日期：2015-06-01 00:00:00

abstract：:The purpose of this case-control study is to estimate the risks of Stevens-Johnson syndrome or toxic epidermal necrolysis associated with the use of specific drugs. The suspected cases were identified from the computerized hospital discharge file. We calculated crude relative risks and adjusted them for confounding by...

journal_title：Internal medicine journal

authors： Lin MS,Dai YS,Pwu RF,Chen YH,Chang NC

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Polyserositis (PS) is the inflammation, with effusion, of different serous membranes. It has been associated with different aetiologies, but the aetiology of PS remains unknown in a high percentage of patients. AIMS:The general objective of this retrospective study was to analyse the aetiology of PS cases s...

journal_title：Internal medicine journal

authors： Losada I,González-Moreno J,Roda N,Ventayol L,Borjas Y,Domínguez FJ,Fernández-Baca V,García-Gasalla M,Payeras A

更新日期：2018-08-01 00:00:00

abstract：:Autologous stem cell transplantation (ASCT) has a well-established role in the treatment of haematological malignancies. Stem cells are commonly collected following salvage chemotherapy although there may be advantages in collecting earlier in the disease course. A 'rainy day' harvest (RDH) refers to the collection of...

journal_title：Internal medicine journal

authors： Trotman J,Presgrave P,Kwan Y,Tiley C,Estell J,Watson AM,O'Brien TA,Peters D

更新日期：2008-04-01 00:00:00

abstract：:Thrombotic microangiopathy (TMA) arises in a variety of clinical circumstances with the potential to cause significant dysfunction of the kidneys, brain, gastrointestinal tract and heart. TMA should be considered in all patients with thrombocytopenia and anaemia, with an immediate request to the haematology laboratory...

journal_title：Internal medicine journal

authors： Fox LC,Cohney SJ,Kausman JY,Shortt J,Hughes PD,Wood EM,Isbel NM,de Malmanche T,Durkan A,Hissaria P,Blombery P,Barbour TD

更新日期：2018-06-01 00:00:00

abstract：:It is generally accepted that the prevalence of food allergy has been increasing in recent decades, particularly in westernised countries, yet high-quality evidence that is based on challenge confirmed diagnosis of food allergy to support this assumption is lacking because of the high cost and potential risks associat...

journal_title：Internal medicine journal

authors： Tang ML,Mullins RJ

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Stroke is an Australian health priority area causing considerable levels of disability. We report 90-day outcomes for a cohort of acute stroke patients in New South Wales (NSW), Australia prior to randomization to a large cluster randomized controlled trial (CRCT), the Quality in Acute Stroke Care (QASC) tri...

journal_title：Internal medicine journal

authors： Middleton S,Levi C,Ward J,Grimshaw J,Griffiths R,D'Este C,Dale S,Quinn C,Evans M,Cadilhac D,McElduff P

更新日期：2011-10-01 00:00:00

abstract：AIMS:To measure factors associated with underuse of beta-blocker therapy after myocardial infarction (MI). METHODS:The Newcastle and Perth collaborating centres of the World Health Organization (WHO) MONICA project (to MONItor trends and determinants of Cardiovascular disease) systematically evaluated all patients adm...

journal_title：Internal medicine journal

authors： Nicholls SJ,McElduff P,Dobson AJ,Jamrozik KD,Hobbs MS,Leitch JW

更新日期：2001-09-01 00:00:00

abstract：:Growth hormone (GH) replacement therapy was recently recommended by the Pharmaceutical Benefits Advisory Committee (PBAC) for listing on the Pharmaceutical Benefits Scheme for adults with severe GH deficiency and impaired quality of life. This approval was significant for two reasons. First, the application was initia...

journal_title：Internal medicine journal

authors： Lipworth W,Ambler G,Burt MG,Fairchild J,Inder WJ,Werther G,Ho K

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The short Synacthen test is widely used to assess the hypothalamus pituitary adrenal axis in the outpatient setting. In the inpatient setting however, technical difficulties to adhere to the protocol may pose a challenge for using this test. AIMS:In this study we attempted to find the most suitable basal se...

journal_title：Internal medicine journal

authors： Tolkin L,Vidberg M,Munter G

更新日期：2020-08-24 00:00:00

abstract：:A retrospective review of patients receiving rituximab off label in a large teaching hospital was conducted between July 2002 and January 2006. The indication, dosing regimen, efficacy and cost of rituximab were evaluated. Rituximab was prescribed for three clinical indications; acute organ transplant rejection, post-...

journal_title：Internal medicine journal

authors： Sharma R,Koller L,Barclay P,Liddle C

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:IgE-mediated allergy to the wheat protein omega-5-gliadin (O5G) is associated with wheat-dependent exercise-induced anaphylaxis (WDEIA), where exercise acts as a cofactor, triggering anaphylaxis after wheat ingestion. The wider application of O5G-specific IgE (sIgE) testing has revealed that the manifestatio...

journal_title：Internal medicine journal

authors： Le TA,Al Kindi M,Tan JA,Smith A,Heddle RJ,Kette FE,Hissaria P,Smith WB

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Timely administration of intravenous tissue plasminogen activator (IVtPA) for acute ischaemic stroke is associated with better clinical outcomes. Therefore, a coordinated hospital system of acute clinical assessment and neuroimaging will likely avoid delays in IV-tPA administration. AIM:In July 2007, we imp...

journal_title：Internal medicine journal

authors： Tai YJ,Weir L,Hand P,Davis S,Yan B

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Bronchodilator reversibility (BDR) and inhaled corticosteroid (ICS) use were assessed for volunteers who responded to an advertisement requesting current or ex-smokers who were experiencing breathlessness to attend for lung function testing. METHODS:One hundred and fifty-four volunteers responded. ...

journal_title：Internal medicine journal

authors： Reid DW,Soltani A,Johns DP,Bish R,Williams TJ,Burns GP,Walters EH

更新日期：2003-12-01 00:00:00

abstract：:Significant developments have occurred in the discipline of palliative care in the modern era. This paper shall explore those developments, challenge some widely held misconceptions about the role and daily practice of the discipline, highlight the growing recognition of the role of palliative care in non-malignant di...

journal_title：Internal medicine journal

authors： Brennan F

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Peptide receptor radionuclide therapy with 177 Lu-DOTATATE is a promising treatment for inoperable or metastatic neuroendocrine tumours (NET). In 2015, the NSW Ministry of Health provided funding for 177 Lu-DOTATATE treatment of NET under an evaluation framework. AIMS:To examine the safety and outcomes of N...

journal_title：Internal medicine journal

authors： Lin E,Chen T,Little A,Holliday L,Roach P,Butler P,Hosking E,Bailey E,Elison B,Currow D

更新日期：2019-10-01 00:00:00

abstract：:We hereby present two case reports of moderate coronavirus disease patients, suffering from profound hypoxaemia, further deteriorating later on. A schedule pre-planned awake prone position manoeuvres were executed during their hospital stay. Following this, the patients' saturation improved, later to be weaned from ox...

journal_title：Internal medicine journal

authors： Cohen D,Wasserstrum Y,Segev A,Avaky C,Negru L,Turpashvili N,Anani S,Zilber E,Lasman N,Athamna A,Segal O,Shenhav-Saltzman G,Segal G

更新日期：2020-08-01 00:00:00

abstract：INTRODUCTION:In patients with chronic idiopathic thrombocytopenic purpura (cITP), the platelet count tends to be quite variable and, in the majority of cases, specific therapy is not warranted on a regular basis. However, patients with low platelet count (<30 nL) or with bleeding complications would require therapy, su...

journal_title：Internal medicine journal

authors： Ramakrishna R,Rehman A,Ramakrishna S,Alexander W,Yeo WW

更新日期：2015-07-01 00:00:00

abstract：:Legionella species are a common cause of community-acquired pneumonia, infrequently complicated by cavitary disease. We describe Legionella pneumophila pneumonia and abscess formation in an immunosuppressed patient receiving corticosteroid therapy for metastatic breast carcinoma. The predisposing role of corticosteroi...

journal_title：Internal medicine journal

authors： Guy SD,Worth LJ,Thursky KA,Francis PA,Slavin MA

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:High inflammatory bowel disease (IBD) rates have been reported in Australasia, but no state-wide studies have yet been performed. AIM:This study estimates the 1-year incidence and point prevalence of IBD in the state of Tasmania, Australia. It also reports clinical outcomes after 12 months of diagnosis in a...

journal_title：Internal medicine journal

authors： Bhatia R,Yeoh SW,Vaz K,Studd C,Wilson J,Bell S,Otahal P,Venn A

更新日期：2019-05-01 00:00:00

abstract：AIM:To explore and detail clinical experiences of dabigatran, a novel anticoagulant, after it became available in New Zealand in July 2011. METHODS:A cohort of patients was recruited from Hutt Hospital and the two largest primary care practices in the Hutt Valley region. They were included if they took at least one do...

journal_title：Internal medicine journal

authors： Thorne K,Jayathissa S,Dee S,Briggs N,Taylor J,Reid S,De Silva K,Dean J

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:The association between the use of angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB) and mortality in end-stage renal disease (ESRD) patients lacks sufficient evidence. AIM:To investigate the efficacy of ACEI and ARB in ESRD patients. METHODS:This nationwide retrospect...

journal_title：Internal medicine journal

authors： Lee HF,See LC,Chan YH,Yeh YH,Wu LS,Liu JR,Tu HT,Wang CL,Kuo CT,Chang SH

更新日期：2018-09-01 00:00:00