Novel gain of function mutation in the SLC40A1 gene associated with hereditary haemochromatosis type 4.

abstract：BACKGROUND:Congestive heart failure (CHF) is a frequent complication of most diseases of the heart. CHF is associated with impairment in several aspects of the quality of life of patients, including mood and cognitive performance. Early reports indicated that patients with CHF display deficits in memory and other intel...

journal_title：Internal medicine journal

authors： Almeida OP,Flicker L

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Patients who suffer from acute IgE-mediated allergy to a cephalosporin antibiotic are frequently assumed to be at high risk of allergy to other cephalosporins and penicillins. AIM:To define cross-reactivity patterns in patients with confirmed allergy to a cephalosporin. METHODS:Subjects presenting with a h...

journal_title：Internal medicine journal

authors： Yuson C,Kumar K,Le A,Ahmadie A,Banovic T,Heddle R,Kette F,Smith W,Hissaria P

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Type 2 diabetes (T2D) in young adults is associated with a high risk of diabetes complications. AIMS:To investigated the demography and the emergence of complications of young adults with T2D in the central Auckland region where there has been substantial immigration. METHODS:In total, 310 young adults wit...

journal_title：Internal medicine journal

authors： Beig J,Khanolkar M,Cundy T

更新日期：2018-01-01 00:00:00

abstract：:Environmental exposures in the foetal period may predispose to autoimmunity. Aim of this study is to investigate whether seasonality in birth patterns exists in idiopathic inflammatory myopathies (IIM). We used Stata (StataCorp USA, version 13.0) and the user-written routine command 'circsummarise' to assess birth sea...

journal_title：Internal medicine journal

authors： Woodman R,Hakendorf P,Limaye V

更新日期：2016-05-01 00:00:00

abstract：AIM:To carry out an audit of the appropriateness of fresh-frozen plasma (FFP) and platelets (Plt) transfusion with reference to the Australian National Health and Medical Research Council/Australian Society of Blood Transfusion Clinical Practice Guidelines, and to assess the impact of a self-educating transfusion reque...

journal_title：Internal medicine journal

authors： Hui CH,Williams I,Davis K

更新日期：2005-05-01 00:00:00

abstract：:The incidence of tuberculosis in the non-indigenous Australian population is low. However, in this paper we report on three cases of cavitating disease, which seem to be associated with a common illicit drug habit namely smoking marijuana using a makeshift pipe or bong. There was a total of 34 positive contacts of the...

journal_title：Internal medicine journal

authors： Thu K,Hayes M,Miles S,Tierney L,Foy A

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Smartphones have become novel healthcare tools for patients with diabetes. However, it is uncertain whether the smartphone application support system helps in glycaemic control in patients with type 2 diabetes. AIMS:To evaluate the efficacy and plausibility of smartphone-based integrated online real-time di...

journal_title：Internal medicine journal

authors： Ku EJ,Park JI,Jeon HJ,Oh T,Choi HJ

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Cigarette smoking prevalence has been declining over decades in Western countries especially in higher socioeconomic groups. Employees of Australian hospitals span the socioeconomic spectrum, but there are few data on smoking prevalence from these workplaces. Because smoking is a health hazard, some argue th...

journal_title：Internal medicine journal

authors： Jones TE,Williams J

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The thiopurines azathioprine and 6-mercaptopurine are recommended for maintenance of remission in inflammatory bowel disease (IBD). Measurement of concentrations of the metabolites 6-thioguanine nucleotide and 6-methylmercaptopurine helps delineate interindividual variation in metabolism that may underlie va...

journal_title：Internal medicine journal

authors： Kennedy NA,Asser TL,Mountifield RE,Doogue MP,Andrews JM,Bampton PA

更新日期：2013-03-01 00:00:00

abstract：AIM:To study the sputum microbiology of patients admitted to a teaching hospital with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) with concomitant pneumonia. METHODS:This was a retrospective study in a tertiary university hospital in Hong Kong. All episodes of AECOPD with pneumonia, patient d...

journal_title：Internal medicine journal

authors： Ko FW,Lam RK,Li TS,Fok JP,Chan MC,Ng TK,Chan DP,Hui DS

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Stroke is an Australian health priority area causing considerable levels of disability. We report 90-day outcomes for a cohort of acute stroke patients in New South Wales (NSW), Australia prior to randomization to a large cluster randomized controlled trial (CRCT), the Quality in Acute Stroke Care (QASC) tri...

journal_title：Internal medicine journal

authors： Middleton S,Levi C,Ward J,Grimshaw J,Griffiths R,D'Este C,Dale S,Quinn C,Evans M,Cadilhac D,McElduff P

更新日期：2011-10-01 00:00:00

abstract：:The mortality rate post admission to hospital after successful resuscitation from out-of-hospital cardiac arrest is high, with significant variation between regions and individual institutions. While prehospital factors such as age, bystander cardiopulmonary resuscitation and total cardiac arrest time are known to inf...

journal_title：Internal medicine journal

authors： Stub D,Bernard S,Smith K,Bray JE,Cameron P,Duffy SJ,Kaye DM

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The parenteral administration of oestradiol acutely protects against exercise-induced myocardial ischaemia in women, but whether this effect is sex-specific is not known. AIMS:The effects of acutely administered conjugated equine oestrogen on exercise-induced myocardial ischaemia in men with established cor...

journal_title：Internal medicine journal

authors： Davis SR,Bradbury J,Bell R,Johns JA

更新日期：2003-05-01 00:00:00

abstract：:Cardiac involvement is not regarded as a feature of Henoch-Schönlein purpura (HSP). We report a patient with HSP who developed significant cardiac symptoms, which resolved with immunosuppression. We review previous cases of HSP with cardiac features, none of which showed a response to treatment, and discuss evidence t...

journal_title：Internal medicine journal

authors： Polizzotto MN,Gibbs SD,Beswick W,Seymour JF

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Bali, Indonesia, presents significant infectious and non-infectious health risks for Australian travellers. Understanding this spectrum of illnesses has the potential to assist clinicians in evaluating unwell returning travellers and guide provision of pre-travel advice. AIM:To describe the spectrum of illn...

journal_title：Internal medicine journal

authors： Sohail A,McGuinness SL,Lightowler R,Leder K,Jomon B,Bain CA,Peleg AY

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Quick Sepsis-related Organ Failure Assessment (qSOFA) is recommended for use by the most recent international sepsis definition taskforce to identify suspected sepsis in patients outside the Intensive Care Unit (ICU) at risk of adverse outcomes. Evidence of its comparative effectiveness with existing sepsis ...

journal_title：Internal medicine journal

authors： Li L,Rathnayake K,Green M,Shetty A,Fullick M,Walter S,Middleton-Rennie C,Meller M,Braithwaite J,Lander H,Westbrook JI

更新日期：2020-01-06 00:00:00

abstract：BACKGROUND:Frailty is common among acute hospital patients and might adversely affect recovery from inpatient cardiac arrest. AIM:To assess the relationship between hospital admission characteristics, including frailty, and discharge outcome after in-hospital cardiac arrest. METHODS:Prospectively collected data were ...

journal_title：Internal medicine journal

authors： Smith RJ,Reid DA,Santamaria JD

更新日期：2019-08-01 00:00:00

abstract：:Lymphangioleiomyomatosis (LAM) is a rare disease affecting women, classically involving the lungs. However, extrapulmonary manifestations also occur, including renal angiomyolipomas, retroperitoneal lymphangioleiomyomas and extrathoracic lymphadenopathy. The lung disease is hormone-responsive, but no information exist...

journal_title：Internal medicine journal

authors： Sandrini A,Silverstone E,Yates DH

更新日期：2011-12-01 00:00:00

abstract：AIM:Bigge Park Centre (BPC) is a sexual health clinic located in a socially disadvantaged area in Southwest Sydney. This served as a retrospective clinical audit, documenting patient demographics, identifying factors associated with virological, immunological and discordant responses, evaluating the centre's ability in...

journal_title：Internal medicine journal

authors： Hsu DC,Quin JW

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:The relationship between serum triglycerides (TG) level and the risk of coronary heart disease (CHD) mortality remains controversial. AIMS:To evaluate whether TG level is a risk factor for CHD in elderly people from general population, and to look for interactions between TG and other risk factors. METHODS...

journal_title：Internal medicine journal

authors： Mazza A,Tikhonoff V,Schiavon L,Casiglia E

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Current diagnostic tools are inadequate for reliable prediction of prostate cancer (PCa) aggressiveness in patients with localised disease. This results in many patients being exposed to potentially unnecessary invasive treatment and its associated morbidities. In order to develop appropriate treatment strat...

journal_title：Internal medicine journal

authors： Algotar AM,Thompson PA,Ranger-Moore J,Stratton MS,Hsu CH,Ahmann FR,Nagle RB,Stratton SP

更新日期：2012-04-01 00:00:00

abstract：:A prospective study of non-invasive ventilation at The Prince Charles Hospital outside of the intensive care unit from March 2015 to March 2016 was performed. Overall 69 patients were included. Acute hypercapnic respiratory failure was the most common indication (n = 59; 85%). 49 (71%) had multifactorial respiratory f...

journal_title：Internal medicine journal

authors： Smith DB,Tay GTP,Hay K,Antony J,Bell B,Kinnear FB,Curtin DL,Douglas J

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Interstitial lung disease (ILD) and pulmonary arterial hypertension (PAH) represent the leading causes of death in systemic sclerosis (SSc). Screening for these complications has assumed greater importance, but is not universal. The aim of this study is to determine the self-reported screening, diagnosis and...

journal_title：Internal medicine journal

authors： Mangat P,Conron M,Gabbay E,Proudman SM,Pulmonary Interstitial Vascular Organisational Taskforce (PIVOT).

更新日期：2010-07-01 00:00:00

abstract：:It is generally accepted that the prevalence of food allergy has been increasing in recent decades, particularly in westernised countries, yet high-quality evidence that is based on challenge confirmed diagnosis of food allergy to support this assumption is lacking because of the high cost and potential risks associat...

journal_title：Internal medicine journal

authors： Tang ML,Mullins RJ

更新日期：2017-03-01 00:00:00

abstract：:Common peroneal neuropathy (CPN) may develop unexpectedly in patients with underlying cancer. To clarify the underlying pathophysiology, clinical and neurophysiological data were prospectively collected from 10 oncology clinic patients referred for neurological assessment after the onset of foot weakness. In all patie...

journal_title：Internal medicine journal

authors： Simon NG,Kiernan MC

更新日期：2012-07-01 00:00:00

abstract：AIM:Premature discontinuation of antiplatelet therapy is an independent predictor of late stent thrombosis. We sought to determine the prevalence and predictors of premature discontinuation of antiplatelet therapy after drug-eluting stent implantation among patients in Asia. METHODS:A total of 207 consecutive patients...

journal_title：Internal medicine journal

authors： Poh CL,Chan MY,Lau C,Teo SG,Low AF,Tan HC,Lee CH

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, enters human cells by binding of its viral protein to the aminopeptidase angiotensin-converting enzyme 2 (ACE2). This has led to speculation whether treatment with renin-angiotensin system (RAS) inhibitors was asso...

journal_title：Internal medicine journal

authors： Koshy AN,Murphy AC,Farouque O,Ramchand J,Burrell LM,Yudi MB

更新日期：2020-12-01 00:00:00

abstract：:This review summarises the available clinical trials data investigating the effects of glucose lowering on mortality in patients admitted to hospital with acute myocardial infarction. The results of these studies are inconclusive with no clear evidence that this intervention has additional benefit over and above routi...

journal_title：Internal medicine journal

authors： Braatvedt GD

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Effective clinical handover has always been integral to delivering safe, high-quality care in medical wards. AIM:As handover activity increases in importance we wanted to explore the experience of physicians and trainee doctors. There is little research on internal medicine handover with even less based on ...

journal_title：Internal medicine journal

authors： Donnelly S,Dinesh D,Dew K,Stubbe M

更新日期：2019-05-01 00:00:00

abstract：:Haemophagocytic lymphohistiocytosis (HLH) is rare disorder characterised by immune activation leading to cytokine storm and end-organ failure. It is associated with poor prognosis. HLH is predominantly a disease of early childhood, where it often results from genetic defects that impair cytotoxic function of natural k...

journal_title：Internal medicine journal

authors： Lee WI,Talaulikar D,Cook MC

更新日期：2020-05-10 00:00:00