Abstract:
:Systemic lupus erythematosus (SLE) has been described as a cause of thrombotic microangiopathy, especially thrombotic thrombocytopenic purpura (TTP). Haemolytic-uraemic syndrome (HUS) is less frequent in SLE. We report a case of such an association during an episode of severe lupus nephritis in a young woman, who was successfully treated with steroids, cyclophosphamide and especially plasma exchange with plasma replacement. This report highlights the importance of recognising atypical HUS in SLE patients by looking for schistocytes in case of haemolytic anemia with a negative antiglobulin test, in order to begin plasma exchange.
journal_name
Intern Med Jjournal_title
Internal medicine journalauthors
Samson M,Audia S,Leguy V,Berthier S,Janikashvili N,Martin L,Bonnotte B,Lorcerie Bdoi
10.1111/j.1445-5994.2011.02591.xsubject
Has Abstractpub_date
2012-01-01 00:00:00pages
95-8issue
1eissn
1444-0903issn
1445-5994journal_volume
42pub_type
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