Abstract:
:Autologous stem cell transplantation (ASCT) has a well-established role in the treatment of haematological malignancies. Stem cells are commonly collected following salvage chemotherapy although there may be advantages in collecting earlier in the disease course. A 'rainy day' harvest (RDH) refers to the collection of autologous haemopoietic stem cells for long-term storage. Although there are few data to support RDH, there is increasing evidence that such harvests are being carried out, creating storage pressures in stem cell laboratories across New South Wales. The Bone Marrow Transplant Network New South Wales conducted a three-staged exercise to develop consensus-based RDH guidelines. Using available evidence, guidelines were developed supporting RDH for specific patients with acute and chronic myeloid leukaemias, follicular and other lymphomas, and multiple myeloma. Physician agreement with these disease-specific guidelines ranged between 58 and 100%. These consensus guidelines will improve equity of access to appropriate RDH and assist the planning of future storage requirements in New South Wales.
journal_name
Intern Med Jjournal_title
Internal medicine journalauthors
Trotman J,Presgrave P,Kwan Y,Tiley C,Estell J,Watson AM,O'Brien TA,Peters Ddoi
10.1111/j.1445-5994.2008.01632.xsubject
Has Abstractpub_date
2008-04-01 00:00:00pages
229-34issue
4eissn
1444-0903issn
1445-5994pii
IMJ1632journal_volume
38pub_type
杂志文章abstract::Abstract Hyperammonaemic encephalopathy has been infrequently reported after both standard and high-dose chemotherapy for solid and haematological malignancies. It is important to consider this diagnosis for patients with unexplained behaviour changes or encephalopathy and this case report emphasizes this condition an...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2008.01772.x
更新日期:2008-10-01 00:00:00
abstract:BACKGROUND:A number of haematological malignancies can be cured by allogeneic stem cell transplantation but only approximately 30% of Australians have a suitable histocompatible related donor. Matched donors can be found on international registries of unrelated volunteers for a proportion of the remaining patients. For...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2006.01079.x
更新日期:2006-06-01 00:00:00
abstract::Clarithromycin is the most documented cytochrome P450 3A4 (CYP3A4) inhibitor to cause an adverse interaction with simvastatin. This particular case is of interest as rhabdomyolysis only occurred after an increase in the dose of clarithromycin. The patient developed raised cardiac biomarkers without any obvious cardiac...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.12464
更新日期:2014-07-01 00:00:00
abstract::This paper uses a case example to review the current legal status of advance directives, as well as their ethical rationale. We draw attention to ongoing efforts to institutionalize advance directives, and to some of the tractable and intractable reasons why advance directives are ineffective. We then introduce the co...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2005.00915.x
更新日期:2005-09-01 00:00:00
abstract::It is generally accepted that the prevalence of food allergy has been increasing in recent decades, particularly in westernised countries, yet high-quality evidence that is based on challenge confirmed diagnosis of food allergy to support this assumption is lacking because of the high cost and potential risks associat...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13362
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Inequalities in access to renal services and acute care for rural and remote populations in Australia have been described but not quantified. AIM:To describe: the coverage of renal disease management services in rural and remote Australia; and the characteristics of patients who had an aeromedical retrieval...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14716
更新日期:2020-08-01 00:00:00
abstract::Previous reports have noted an association between membranous nephropathy and focal segmental glomerulosclerosis with Guillain-Barre syndrome. We report a case of Campylobacter enteritis, which was complicated by both focal segmental glomerulosclerosis of the collapsing variety and Guillain-Barre syndrome, and propose...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2007.01458.x
更新日期:2007-10-01 00:00:00
abstract::Neuroimaging in dementia has focused on documenting any burden of vascular disease or excluding any reversible intracranial pathology. We review the use of computed tomography to examine for medial temporal lobe atrophy in dementia and compare this with a case series of such measurements from our memory clinic. Measur...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/j.1445-5994.2007.01598.x
更新日期:2008-02-01 00:00:00
abstract::A 22-year-old woman presented with methanol toxicity manifesting as headache, reduced conscious state and visual change after consuming home-made grappa. She progressed to a coma with fixed mydriasis and severe acidaemia (pH 6.55). She was treated with empirical antidote administration (intravenous ethanol) and enhanc...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13725
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Infections and antibiotic resistance patterns in patients attending regional Australian cancer centres are poorly described. AIMS:To document patient characteristics, infection types, patterns of antibiotic resistance and outcomes in all patients with cancer requiring inpatient management for suspected infe...
journal_title:Internal medicine journal
pub_type: 信件
doi:10.1111/imj.13646
更新日期:2018-03-01 00:00:00
abstract::Thrombotic microangiopathy (TMA) is a potentially fatal complication in solid organ and bone marrow transplant patients, with reported incidence of 0.5-3% and mortality of about 75%. To emphasise the importance of early diagnosis and prompt commencement of therapy results in improved clinical outcomes. A retrospective...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/imj.12048
更新日期:2013-03-01 00:00:00
abstract::Inappropriate polypharmacy and its associated harm pose a significant threat to older patients. The prescribing decisions of physicians greatly influence what other practitioners prescribe. Minimising medication-related harm requires physicians to adopt a systematic approach to the deliberate and judicious deprescribi...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/imj.12693
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Patients who suffer from acute IgE-mediated allergy to a cephalosporin antibiotic are frequently assumed to be at high risk of allergy to other cephalosporins and penicillins. AIM:To define cross-reactivity patterns in patients with confirmed allergy to a cephalosporin. METHODS:Subjects presenting with a h...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14229
更新日期:2019-08-01 00:00:00
abstract::Extramedullary haemopoiesis (EMH) is a complication commonly associated with beta-thalassaemia intermedia; it is frequently asymptomatic but can sometimes lead to symptomatic tumour-like masses. No guidelines or common consensus are available in literature regarding the different treatment strategies and only single c...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/imj.12386
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Anticipating the prospect of specific treatment, we studied a large group of Australians with Fabry's disease. AIMS:We aimed to: (i) document the clinical features of Fabry's disease in Australian patients, (ii) test the hypothesis that clinical features vary with specific mutation and blood group and (iii)...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1046/j.1445-5994.2002.00291.x
更新日期:2002-12-01 00:00:00
abstract:BACKGROUND:A Resuscitation Plan is a medically authorised order to use or withhold resuscitation interventions. Absence of appropriate resuscitation orders exposes patients to the risk of invasive medical interventions that may be of questionable benefit depending on individual circumstances. AIMS:To describe among ju...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14994
更新日期:2020-07-20 00:00:00
abstract:AIM:Bigge Park Centre (BPC) is a sexual health clinic located in a socially disadvantaged area in Southwest Sydney. This served as a retrospective clinical audit, documenting patient demographics, identifying factors associated with virological, immunological and discordant responses, evaluating the centre's ability in...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2009.01983.x
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND AND AIMS:Cardiac myxoma is a rare but important cause of stroke, which affects young people. More recently the diagnosis has been enhanced by the use of echocardiograms. We aimed to review the neurological presentations, including stroke, of cardiac myxoma in this modern era of diagnosis and management. MET...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/j.1444-0903.2004.00563.x
更新日期:2004-05-01 00:00:00
abstract::Based on the number of new cases (incidence), non-Hodgkin lymphoma is an increasingly common cancer in Australia and many developed countries. Until recently, mortality trends have been stable or slightly increasing. However, since the year 2000, mortality has decreased every year by an average of 5.1% per year (95% c...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2008.01809.x
更新日期:2008-12-01 00:00:00
abstract::This paper examines the differences between clinical and public health ethics and provides several examples of contemporary public health challenges that pose ethical questions. The relations among ethics, rights and obligations are explored, because public health philosophers propose these as different ways for publi...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/j.1445-5994.2004.00643.x
更新日期:2004-07-01 00:00:00
abstract:AIM:To carry out an audit of the appropriateness of fresh-frozen plasma (FFP) and platelets (Plt) transfusion with reference to the Australian National Health and Medical Research Council/Australian Society of Blood Transfusion Clinical Practice Guidelines, and to assess the impact of a self-educating transfusion reque...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2005.00803.x
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND:Clopidogrel is an antiplatelet drug increasingly used in the secondary prevention of atherosclerotic vascular events. Compared with aspirin, clopidogrel has marginal additional efficacy and similar safety, but carries a substantial price premium. It remains unclear whether its use is cost-effective. AIMS:(i...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2004.00697.x
更新日期:2004-12-01 00:00:00
abstract::Waldenström macroglobulinaemia (WM) is an indolent B-cell malignancy characterised by the presence of immunoglobulin M (IgM) paraprotein and bone marrow infiltration by clonal small B lymphocytes, plasmacytoid lymphocytes and plasma cells. The symptoms of WM are protean, often follow an asymptomatic phase and may incl...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13311
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:The international literature advocates for cancer screening in newly diagnosed patients with autoimmune myositis; however, there is no widely accepted consensus or guideline to outline the optimal cancer screening strategy and the evidence is currently insufficient to support any recommendation. AIM:Our stu...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13556
更新日期:2017-12-01 00:00:00
abstract::Sodium-glucose co-transporter 2 inhibitors (SGLT2i) are an increasingly prescribed class of medication for type 2 diabetes mellitus. Euglycaemic diabetic ketoacidosis (euDKA) has been reported in association with SGLT2i use. Clinicians need to understand how to recognise and treat this complication. We describe three ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13442
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Frailty is common among acute hospital patients and might adversely affect recovery from inpatient cardiac arrest. AIM:To assess the relationship between hospital admission characteristics, including frailty, and discharge outcome after in-hospital cardiac arrest. METHODS:Prospectively collected data were ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14159
更新日期:2019-08-01 00:00:00
abstract::Decompressive hemicraniectomy (DHC) has been shown to reduce mortality in malignant middle cerebral artery (MCA) infarction. Our primary objective was to compare 1-year mortality between patients receiving DHC for malignant MCA infarction at our institution based on hospital of origin. We retrospectively reviewed the ...
journal_title:Internal medicine journal
pub_type: 杂志文章,meta分析
doi:10.1111/imj.14050
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:The consumption of Energy Drinks (Edks), has increased significantly in the last years, with a growing market that is estimated to reach $61 billion by 2021 worldwide. Several studies demonstrated the physiological and pathological effects of these substances contained in Edks. The most common ingredient con...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/imj.14881
更新日期:2020-05-05 00:00:00
abstract:BACKGROUND: According to the International Prognostic Scoring System (IPSS), sole +8 is categorized as intermediate cytogenetic subgroup. But as some myelodysplastic syndrome (MDS) patients with +8 perhaps progress quickly to acute leukaemia and have shorter survival, some reports have suggested that +8 should be cate...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2009.02061.x
更新日期:2010-10-01 00:00:00
abstract::Lymphangioleiomyomatosis (LAM) is a rare disease affecting women, classically involving the lungs. However, extrapulmonary manifestations also occur, including renal angiomyolipomas, retroperitoneal lymphangioleiomyomas and extrathoracic lymphadenopathy. The lung disease is hormone-responsive, but no information exist...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2011.02593.x
更新日期:2011-12-01 00:00:00